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| 1 | Template-Free Synthesis of Ordered Mesoporous NiO/Poly (Sodium-4-Styrene Sulfonate) Functionalized Carbon Nanotubes Composite for Electrochemical Capacitors显示文摘We report the first example of a practical and efficient template-free strategy for synthesizing ordered mesoporous NiO/poly(sodium-4-styrene sulfonate)(PSS)functionalized carbon nanotubes(FCNTs)composites by calcining a Ni(OH)_(2)/FCNTs precursor prepared by refl uxing an alkaline solution of Ni(NH_(3))x^(2)+and FCNTs at 97 oC for 1 h.The morphology and structure were characterized by X-ray diffraction,scanning electron microscopy,and transmission electron microscopy.Thermal decomposition of the precursor results in the formation of ordered mesoporous NiO/FCNTs composite(ca.48 wt%NiO)with large specifi c surface area.Due to its enhanced electronic conductivity and hierarchical(meso-and macro-)porosity,composite simultaneously meets the three requirements for energy storage in electrochemical capacitors at high rate,namely,good electron conductivity,highly accessibleelectrochemical surface areas owing to the existence of mesopores,and efficient mass transport from the macropores.Electrochemical data demonstrated that the ordered mesoporous NiO/FCNTs composite is capable of delivering a specifi c capacitance(SC)of 526 F/g at 1 A/g and a SC of 439 F/g even at 6 A/g,and show a degradation of only ca.6%in SC after 2000 continuous charge/discharge cycles. | Changzhou Yuan Shenglin Xiong Xiaogang Zhang Laifa Shen Fang Zhang Bao Gao Linhao Su | 2009 | Nano Research2009，2，9： | 1 |
| 2 | Plant and animal positive-sense single-stranded RNA viruses encode small proteins important for viral infection in their negative-sense strand显示文摘Positive-sense single-stranded RNA(+ssRNA)viruses,the most abundant viruses of eukaryotes in nature,require the synthesis of negative-sense RNA(-RNA)using their genomic(positive-sense)RNA(+RNA)as a template for replication.Based on current evidence,viral proteins are translated via viral+RNAs,whereas-RNA is considered to be a viral replication intermediate without coding capacity.Here,we report that plant and animal+ssRNA viruses contain small open reading frames(ORFs)in their-RNA(reverse ORFs[rORFs]).Using turnip mosaic virus(TuMV)as a model for plant+ssRNA viruses,we demonstrate that small proteins encoded by rORFs display specific subcellularlocalizations,and confirm the presence of rORF2 in infected cells through mass spectrometry analysis.The protein encoded by TuMV rORF2 forms punctuate granules that are localized in the perinuclear region and co-localized with viral replication complexes.The rORF2 protein can directly interact with the viral RNA-dependent RNA polymerase,and mutation of rORF2 completely abolishes virus infection,whereas ectopic expression of rORF2 rescues the mutant virus.Furthermore,we show that several rORFs in the-RNA of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)have the ability to suppress type l interferon production and facilitate the infection of ve-sicular stomatitis virus.In addition,we provide evidence that TuMV might utilize internal ribosome entry sites to translate these small rORFs.Taken together,these findings indicate that the-RNA of+ssRNA vi-ruses can also have the coding capacity and that small proteins encoded therein play critical roles in viral infection,revealing a viral proteome larger than previously thought. | Pan Gong Qingtang Shen Mingzhen Zhang Rui Qiao Jing Jiang Lili Su Siwen Zhao Shuai Fu Yu Ma Linhao Ge Yaqin Wang Rosa Lozano-Durán Aiming Wang Fangfang Li Xueping Zhou | 2023 | Molecular Plant2023，16，11： | 0 |
| 3 | CH02 peptide promotes ex vivo expansion of umbilical cord blood-derived CD34+hematopoietic stem/progenitor cells显示文摘Umbilical cord blood(UCB)is an advantageous source for hematopoietic stem/progenitor cell(HSPC)transplantation,yet the current strategies for large-scale and cost-effective UCB-HSPC preparation are still unavailable.To overcome these obstacles,we systematically evaluate the feasibility of our newly identified CH02 peptide for ex vivo expansion of CD34^(+)UCB-HSPCs.We herein report that the CH02 peptide is specifically enriched in HSPC proliferation via activating the FLT3 signaling.Notably,the CH02-based cocktails are adequate for boosting 12-fold ex vivo expansion of UCB-HSPCs.Meanwhile,CH02-preconditioned UCB-HSPCs manifest preferable efficacy upon wound healing in diabetic mice via bidirectional orchestration of proinflammatory and anti-inflammatory factors.Together,our data indicate the advantages of the CH02-based strategy for ex vivo expansion of CD34^(+)UCB-HSPCs,which will provide new strategies for further development of large-scale HSPC preparation for clinical purposes. | Yiqi Yang Bihui Zhang Junye Xie Jingsheng Li Jia Liu Rongzhan Liu Linhao Zhang Jinting Zhang Zijian Su Fu Li Leisheng Zhang An Hong Xiaojia Chen | 2023 | Acta Biochimica et Biophysica Sinica2023，55，10： | 0 |
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