|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Preliminary results of FeO mapping using Imaging Interferometer data from Chang'E-1显示文摘Information about the variability,and spatial distribution of iron abundance is important to understand lunar geological history and for future resource utilization. In this paper we present a preliminary model to produce an iron abundance map using images taken by an Imaging Interferometer on board the satellite Chang'E-1. Compared with the Clementine UVVIS images,the images from the Chang'E-1 satellite also allowed for the extraction of FeO abundance distributions on the Moon. However,the prelimi-nary model results suggest an underestimation of ~2 wt.% for the FeO content of the mare region and an overestimation of ~3 wt.% for the highland region. | LING ZongCheng ZHANG Jiang LIU JianZhong ZHANG WenXi BIAN Wei REN Xin MU LingLi LIU JianJun LI ChunLai | 2011 | Chinese Science Bulletin2011，56，4： | 15 |
| 2 | Chang'E-1 Lunar Mission:An Overview and Primary Science Results显示文摘Chang'E-1 is the first lunar mission in China,which was successfully launched on Oct.24th,2007.It was guided to crash on the Moon on March 1,2009,at 52.36°E,1.50°S,in the north of Mare Fecunditatis.The total mission lasted 495 days,exceeding the designed life-span about four months.1.37Terabytes raw data was received from Chang'E-1.It was then processed into 4Terabytes science data at different levels.A series of science results have been achieved by analyzing and applicating these data,especially 'global image of the Moon of China's first lunar exploration mission'.Four scientific goals of Chang'E-1 have been achieved.It provides abundant materials for the research of lunar sciences and cosmochemistry.Meanwhile these results will serve for China's future lunar missions. | Ouyang Ziyuan Li Chunlai Lu Chang Liu Jianzhong Zou Yongliao Zhang Hongbo Jianjun Zuo Wei Su Yah Wen Weibin Bian Wei Zhao Baochang Wang Jianyu Yang Jianfeng Chang Jin Wang Huanyu Zhang Xiaohui Wang Shijin Wang Min Ren Xin Mu Lingli Kong Deqing Wang Xiaoqian Wang Fang Geng Liang Zhang Zhoubin Zheng Lei Zhu Xinying Zheng Yongchun Li Junduo Zou Xiaoduan Xu Chun Shi Shuobiao Gao Yifei Gao Guannan | 2010 | 空间科学学报2010，30，5： | 11 |
| 3 | Preliminary results of TiO_2 mapping using Imaging Interferometer data from Chang'E-1显示文摘The distribution of titanium abundance on the lunar surface is important knowledge for lunar geologic studies and future resource utilization.In this paper,we develop a preliminary model based on'ground truths'from Apollo and Luna sample-return sites to produce a titanium abundance map from Chang’E-1 Imaging Interferometer(IIM) images.The derived TiO2 abundances are validated with Clementine UVVIS results in several regions,including lunar highlands neighboring the Apollo 16 landing site,and high-Ti and low-Ti maria near the standard site of Mare Serenitatis(MS2) .The validation results show that TiO2 abundances modeled with Chang’E-1 IIM data are overestimated for highlands(~0.7 wt.%) and low-Ti maria(~1.5 wt.%) and underestimated for high-Ti maria(~0.8 wt.%). | LING ZongCheng ZHANG Jiang LIU JianZhong ZHANG WenXi ZHANG GuangLiang LIU Bin REN Xin MU LingLi LIU JianJun LI ChunLai | 2011 | Chinese Science Bulletin2011，56，20： | 10 |
| 4 | Data Analysis of Chang'E-1 Gamma-Ray Spectrometer and Global Distribution of U,K,and Th Elemental Abundances显示文摘Gamma 光线分光计(GRS ) 是 Chang'E-1 (CE-1 ) 上的主要收费载重之一月亮的探查,主要试图在月亮的表面上检测元素的丰富和分布。在 03:58 在 2007 年 11 月 28 日,它执行了月亮的 gamma 光线的第一观察。2008 年 10 月 24 日,有效 gamma 光线系列的 2105 h 被 CE-1 GRS 获得了,它盖住月亮的整个表面。这份报纸主要描述处理由使用导出元素的丰富的过程和 CE-1 GRS 时间系列改正了系列的方法的数据:首先,到进为印射的象素的箱数据;然后,执行累积系列的背景扣除并且获得元素的一个山峰区域;并且最后,当模特儿使用元素的丰富倒置生产元素的丰富。在这些上基于比 EPR 在 5s 处理方法, U 的全球丰富地图, K,和 Th。在在 near-EPR 海底山下面的岩浆结晶化压力和融化的条件之间的关联暗示来源吗? | ZOU Yongliao ZHANG Liyan LIU Jianzhong MU Lingli REN Xin ZHANG Guangliang CHANG Jin YAN Jun ZHANG Nan ZHANG Hongbo LU Chang LIU Jianjun ZUO Wei SU Yan WEN Weibin BIAN Wei WANG Min XU Chun LI Chunlai OUYANG Ziyuan | 2011 | Acta Geologica Sinica(English Edition)2011，85，6： | 6 |
| 5 | Cratering process and morphological features of the Xiuyan impact crater in Northeast China显示文摘By using crater impact morphological theory and mathematics modeling,the paper studies the cratering process and morphological features of the Xiuyan Crater in Northeast China based on remote sensing imagery,digital elevation model(DEM)and drilling and measuring data.The results show that:1)Simulated calculation indicates the diameter of the transient crater was1406±12 m and the depth was 497±4 m.The diameter of the final crater was 1758±15 m and the depth was 374.5±3.5 m;the thickness of the breccia lens was 188.5±0.5 m.The data is basically the same as previous drilling data.2)Preliminary determination of the size of Xiuyan impactor:The diameter at about 55 m for an iron meteorite,and about 115 m for a stony meteorite.3)The depth-to-diameter ratio is 0.143,similar to the typical simple crater.The circularity index of the Xiuyan Crater is0.884,indicating erosion and degradation.4)The distribution pattern of radial fractures has priority in NW-SE and WNW-ESE and these fractures control the development and evolution of drainage inside the crater. | WANG XinYuan LUO Lei GUO HuaDong MU LingLi LI Chao JI Wei CAI Heng | 2013 | Science China Earth Sciences2013，56，10： | 4 |
| 6 | Global detection of large lunar craters based on the CE-1 digital elevation model显示文摘坑,月亮的表面的最重要的特征之一,因为他们为我们提供表面单位以及关键地质的信息的相对年龄,广泛地被研究了。关于月亮和另外的行星的身体的算法(CDA ) 专注于从形象数据检测他们的坑察觉的研究,而是检测使用的大坑的计算费用想象使这些 CDA 不切实际。这篇论文介绍一条新途径给利用一个数字举起模型而不是图象的坑察觉;这启用大坑的充分自动的全球察觉。坑被地面属性,然后 thresholding 描出地面属性的地图被用来把地志的数据转变成一幅二进制图象,最后,坑被从二进制图象使用 Hough 变换检测。由使用建议算法,我们生产了所有坑的一个目录在月亮的表面上的直径的 10 km 并且分析了他们的分发和人口特征。 | Lei LUO Lingli MU Xinyuan WANG Chao LI Wei JI Jinjin ZHAO Heng CAI | 2013 | Frontiers of Earth Science2013，7，4： | 3 |
| 7 | Implementation of a reference-scaled average bioequivalence approach for highly variable generic drug products of agomelatine in Chinese subjects显示文摘The aim of this study was to apply the reference-scaled average bioequivalence(RSABE)approach to evaluate the bioequivalence of 2 formulations of agomelatine,and to investigate the pharmacokinetic properties of agomelatine in Chinese healthy male subjects.This was performed in a single-dose,randomized-sequence,open-label,four-way crossover study with a one-day washout period between doses.Healthy Chinese males were randomly assigned to receive 25 mg of either the test or reference formulation.The formulations were considered bioequivalent if 90% confidence intervals(CIs)for the log-transformed ratios and ratio of geometric means(GMR)of AUC and C_(max) of agomelatine were within the predetermined bioequivalence range based on RSABE method.Results showed that both of the90% CIs for the log-transformed ratios of AUC and C_(max) of 7-desmethyl-agomelatine and 3-hydroxyagomelatine were within the predetermined bioequivalence range.The 90% CIs for natural logtransformed ratios of C_(max) ,AUC_(0–t)and AUC_(0–∞) of agomelatine(104.42–139.86,101.33–123.83 and97.90–117.94)were within the RSABE acceptance limits,and 3-hydroxy-agomelatine(105.55–123.03,101.95–109.10 and 101.72–108.70)and 7-desmethyl-agomelatine(104.50–125.23,102.36–111.50 and101.62–110.64)were within the FDA bioequivalence definition intervals(0.80–1.25 for AUC and0.75–1.33 for C_(max)).The RSABE approach was successful in evaluating the bioequivalence of these two formulations. | Fang Tang Rui Zhou Zeneng Cheng Guoping Yang Aiqiao Chen Zhi Liu Hongyi Tan Shuang Yang Sanwang Li Lingli Mu Peng Yu | 2016 | Acta Pharmaceutica Sinica B2016，6，1： | 2 |
| 8 | New techniques of on-line biological sample processing and their application in the field of biopharmaceutical analysis显示文摘Biological sample pretreatment is an important step in biological sample analysis. Due to the diversity of biological matrices, the analysis of target substances in these samples presents significant challenges to sample processing. To meet these emerging demands on biopharmaceutical analysis, this paper summarizes several new techniques of on-line biological sample processing: solid phase extraction, solid phase micro-extraction, column switching, limited intake filler, molecularly imprinted solid phase extraction,tubular column, and micro-dialysis. We describe new developments, principles, and characteristics of these techniques, and the application of liquid chromatography–mass spectrometry(LC–MS) in biopharmaceutical analysis with these new techniques in on-line biological sample processing. | Jie Peng Fang Tang Rui Zhou Xiang Xie Sanwang Li Feifan Xie Peng Yu Lingli Mu | 2016 | Acta Pharmaceutica Sinica B2016，6，6： | 1 |
| 9 | Intracellular pharmacokinetic study of zidovudine and its phosphorylated metabolites显示文摘Zidovudine(AZT), the first drug approved by the US Food and Drug Administration for the treatment of human immunodeficiency virus(HIV) infection, is metabolized in the host cells to 5′-AZT triphosphate(AZT-TP) which inhibits HIV reverse transcriptase. As the pharmacokinetics of AZT and its phosphorylated metabolites in human peripheral blood mononuclear cells(h PBMCs) is limited, the aim of this study was to determine the pharmacokinetic parameters of AZT and its phosphorylated metabolites in h PBMCs from 12 healthy Chinese male subjects after a single oral dose of 600 mg of AZT. Blood samples were collected prior to drug administration, then at 0.5, 1, 1.5, 2, 2.5, 3, 3.5, 4, 5, 6, 8 and 10 h after drug administration. Mononuclear cells collected by Ficoll-Hypaque density gradient centrifugation were used for determination of AZT and metabolites [AZT monophosphate(AZT-MP), AZT diphosphate(AZT-DP) and AZT-TP] and the plasma was used to evaluate the pharmacokinetics of AZT. Plasma concentration of AZT peaked within 0.583 h and intracellular concentrations of AZT, AZT-MP, AZT-DP and AZT-TP peaked within 1.083, 1.500, 1.417 and 1.583 h, respectively. AZT in plasma was eliminated rapidly with t1/2of 2.022 h, and AZT-MP, AZT-DP and AZT-TP were eliminated with t1/2of 13.428,8.285 and 4.240 h, respectively. The plasma concentration of the phosphorylated metabolites was not quantifiable. | Lingli Mu Rui Zhou Fang Tang Xingling Liu Sanwang Li Feifan Xie Xiang Xie Jie Peng Peng Yu | 2016 | Acta Pharmaceutica Sinica B2016，6，2： | 1 |
| 10 | Comparison of Neuroprotec- tive Effects of Flavonoids, Terpenoids and their Combinations from Ginkgo biloba on Ischemia- Reperfusion Injured Mice 显示文摘 | Mu Lingli Kou Junping Zhu Danni | 2007 | Pharm Biol2007，45，9： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员