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| 1 | Grey matter volume abnormalities in patients with bipolar I depressive disorder and unipolar depressive disorder:a voxelbased morphometry study显示文摘Bipolar disorder and unipolar depressive disorder(UD) may be different in brain structure. In the present study,we performed voxel-based morphometry(VBM) to quantify the grey matter volumes in 23 patients with bipolar I depressive disorder(BP1) and 23 patients with UD,and 23 age-,gender-,and educationmatched healthy controls(HCs) using magnetic resonance imaging. We found that compared with the HC and UD groups,the BP1 group showed reduced grey matter volumes in the right inferior frontal gyrus and middle cingulate gyrus,while the UD group showed reduced volume in the right inferior frontal gyrus compared to HCs. In addition,correlation analyses revealed that the grey matter volumes of these regions were negatively correlated with the Hamilton depression rating scores. Taken together,the results of our study suggest that decreased grey matter volume of the right inferior frontal gyrus is a common abnormality in BP1 and UD,and decreasedgrey matter volume in the right middle cingulate gyrus may be specifi c to BP1. | Yi Cai Jun Liu Li Zhang Mei Liao Yan Zhang Lifeng Wang Hongjun Peng Zhong He Zexuan Li Weihui Li Shaojia Lu Yuqiang Ding Lingjiang Li | 2015 | Neuroscience Bulletin2015，31，1： | 11 |
| 2 | Altered regional homogeneity in post-traumatic stress disorder: a resting-state functional magnetic resonance imaging study显示文摘Objective Little is known about the brain systems that contribute to vulnerability to post-traumatic stress disorder (PTSD). Comparison of the resting-state patterns of intrinsic functional synchronization, as measured by functional magnetic resonance imaging (fMRI), between groups with and without PTSD following a traumatic event can help identify the neural mechanisms of the disorder and targets for intervention. Methods Fifty-four PTSD patients and 72 matched traumatized subjects who experienced the 2008 Sichuan earthquake were imaged with blood oxygen level-dependent (BOLD) fMRI and analyzed using the measure of regional homogeneity (ReHo) during the resting state. Results PTSD patients presented enhanced ReHo in the left inferior parietal lobule and right superior frontal gyrus, and reduced ReHo in the right middle temporal gyrus and lingual gyrus, relative to traumatized individuals without PTSD. Conclusion Our findings showed that abnormal brain activity exists under resting conditions in PTSD patients who had been exposed to a major earthquake. Alterations in the local functional connectivity of cortical regions are likely to contribute to the neural mechanisms underlying PTSD. | Yan Yin Changfeng Jin Lisa T. Eyler Hua Jin Xiaolei Hu Lian Duan Huirong Zheng Bo Feng Xuanyin Huang Baoci Shan Qiyong Gong Lingjiang Li | 2012 | Neuroscience Bulletin2012，28，5： | 9 |
| 3 | Altered Motor-Striatal Plasticity and Cortical Functioning in Patients with Schizophrenia显示文摘Patients with schizophrenia undergo changes in brain plasticity. In the present study, we characterized motor cortical-striatal plasticity in such patients. Compared with the potentiation following high-frequency repetitive transcranial magnetic stimulation in the control group, the patients demonstrated impaired plasticity of corticostriatal motor-evoked potentials recorded from hand muscles.Notably, the loss of cortical plasticity was correlated with impaired motor learning in a rotary pursuit task. Moreover,the loss of plasticity was correlated with the symptoms of schizophrenia. The results suggest that the progression of schizophrenia is accompanied by altered cortical plasticity and functioning. | Dongsheng Zhou Feng Pang Shiyan Liu Ying Shen Lingjiang Liu Zezhong Fang Chuang Wang Zhenyu Hu Ti-Fei Yuan | 2017 | Neuroscience Bulletin2017，33，3： | 5 |
| 4 | Adaptive detection for distributed targets in Gaussian noise with Rao and Wald tests显示文摘The problem of adaptively detecting a range distributed target or targets in Gaussian interference is considered in this paper.It is assumed that a set of secondary data is available.Firstly,we derive the adaptive Rao and Wald tests with one-step detection algorithm,and find that both of them are of the same asymptotic performance as the GLRT one.Secondly,the Rao and Wald tests are derived by resorting to the two-step design strategy.To our surprise,our derivations show that all the Rao,Wald and GLR tests in the two-step design strategy are equivalent.Thirdly,the property assessments are presented.It is shown that these new detectors guarantee CFAR property with respect to the Gaussian noise.Finally,simulation results show that these results are accurate. | SHUAI XiaoFei KONG LingJiang YANG JianYu | 2012 | Science China(Information Sciences)2012，55，6： | 5 |
| 5 | Altered functional connectivity networks of hippocampal subregions in remitted late-onset depression:a longitudinal resting-state study显示文摘在迟了生活的消沉(LLD ) 的海马趾的畸形的地区性的特性在以前的研究被表明了。在这研究,我们寻求了检验功能的连接(FC ) 在汇寄的迟了发作的消沉(rLOD ) 的海马趾的分区的模式, LLD 的一种特殊子类型。十四个 rLOD 病人和 18 健康控制象功能的磁性的回声成像在基线并且在 21 月后续扫描的休息状态一样经历了临床、认知的评估。每马头鱼尾的怪兽被划分成三部分,角 ammonis (CA ) ,有牙齿的回转,和 subicular 建筑群,然后六个基于种子的海马趾的分区网络被建立。六个网络的纵的变化直接随着时间的过去在 rLOD 和控制组之间被比较。从基线到后续,在左 CA 的连接给更大的衰落看到双边的以后的 cingulate cortex/precuneus (PCC/PCUN ) ,但是出现的 rLOD 组与正面的外皮(双边的中间的前额的 cortex/anterior cingulate 外皮和增补马达区域) 增加了恰好海马趾的分区网络的连接。进一步的关联词分析表明在在左 CA 和 PCC/PCUN 之间的 FC 的纵的变化断然在标志位形式测试与纵的变化被相关( r = 0.624 , P = 0.017 )并且位跨度测试( r = 0.545 , P = 0.044 )在 rLOD 组得分。这些结果可以提供卓见进在 rLOD 病人位于认知机能障碍下面的 neurobiological 机制。 | Zan Wang Yonggui Yuan Feng Bai Hao Shu Jiayong You Lingjiang Li Zhijun Zhang | 2015 | Neuroscience Bulletin2015，31，1： | 4 |
| 6 | Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia显示文摘Dear Editor,Schizophrenia is a chronic and debilitating brain disorder,which has a strong genetic component with heritability ranging from 66%to 85%[1,2].Currently,antipsychotic drugs remain the most effective treatment for the psychotic symptoms of schizophrenia[3].Because of the severe sideeffects of first-generation antipsychotics(FGAs),secondgeneration antipsychotics(SGAs)have become more widely used in the treatment of schizophrenia. | Liansheng Zhao Huijuan Wang Yamin Zhang Jinxue Wei Peiyan Ni Hongyan Ren Gang Li Qiang Wang Gavin P Reynolds Weihua Yue Wei Deng Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Yinfei Li Hua Yu Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Jeremy Coid Dai Zhang Chao Chen Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Neuroscience Bulletin2019，35，6： | 3 |
| 7 | Testing the role of genetic variation of the MC4R gene in Chinese population in antipsychotic-induced metabolic disturbance显示文摘Antipsychotic-induced metabolic disturbance(AIMD) is a common adverse effect of antipsychotics with genetics partly underpinning variation in susceptibility among schizophrenia patients. Melanocortin4 receptor(MC4 R) gene, one of the candidate genes for AIMD, has been under-studied in the Chinese patients. We conducted a pharmacogenetic study in a large cohort of Chinese patients with schizophrenia. In this study, we investigated the genetic variation of MC4 R in Chinese population by genotyping two SNPs(rs489693 and rs17782313) in 1,991 Chinese patients and examined association of these variants with the metabolic effects that were often observed to be related to AIMD. Metabolic measures, including body mass index(BMI), waist circumference(WC), glucose, triglyceride, high-density lipoprotein(HDL), and low-density lipoprotein(LDL) levels were assessed at baseline and after 6-week antipsychotic treatment. We found that interaction of SNP×medication status(drug-na?ve/medicated) was significantly associated with BMI, WC, and HDL change %, respectively. Both SNPs were significantly associated with baseline BMI and WC in the medicated group. Moderate association of rs489693 with WC, Triglyceride, and HDL change % were observed in the whole sample. In the drug-na?ve group, we found recessive effects of rs489693 on BMI gain more than 7%, WC and Triglyceride change %, with AA incurring more metabolic adverse effects. In conclusion, the association between rs489693 and the metabolic measures is ubiquitous but moderate. Rs17782313 is less involved in AIMD. Two SNPs confer risk of AIMD to patients treated with different antipsychotics in a similar way. | Yamin Zhang Hongyan Ren Qiang Wang Wei Deng Weihua Yue Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Dai Zhang Liansheng Zhao Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Science China(Life Sciences)2019，62，4： | 3 |
| 8 | A cellular automaton model for a bridge traffic bottleneck显示文摘A cellular automaton (CA) model is proposed in this paper to analyze a bridge traffic bottleneck. The simulation results with this model show that there are several phase transitions in the traffic average density, velocity and flow for each lane under a periodic boundary condition. An unstable phase in the traffic average density and velocity for the upstream and downstream lanes of the bridge is shown in a range of initial traffic densities. The critical points of the phase transitions and the phenomenon of the unstable phase found in the simulation are also explained with the mean-field theory. | Shifa Xiao Lingjiang Kong Muren Liu | 2005 | Acta Mechanica Sinica2005，21，3： | 2 |
| 9 | A short 8-item scale for measuring consumers’ local–global identity显示文摘 | Lingjiang Tu Adwait Khare Yinlong Zhang | 2011 | International Journal of Research in Marketing2011，，1： | 2 |
| 10 | Magnetoresistance of the thin film ferromagnetic nanoconstrictions显示文摘The magnetoresistance and I-V characteristics at different temperatures of the thin film ferromagnetic nanoconstrictions of variable width (from 20 to 250 nm) and 10 nm thicknesses, fabricated by electron beam lithography and vacuum thin film deposition are compared. The magnetoresistance and resistance of the thin film ferromagnetic nanoconstrictions are not related to the width of the nanoconstrictions. Instead the resistance of the local nano-region in the middle of the thin film ferromagnetic nanoconstriction has only a minor role compared to that of the two microscale thin film ferromagnetic electrodes, which contribute the majority of the measured resistance. The magnetoresistances of the thin film ferromagnetic nanoconstrictions and a 0.2 cm × 0.8 cm thin ferromagnetic film deposited under the same conditions were also compared; the thin film ferromagnetic nanoconstrictions have higher magnetoresistances than the thin ferromagnetic film, which implies that the measured magnetoresistance of the thin film ferromagnetic nanoconstrictions comes mainly from the local nano-region in their centers. In conclusion, the measured magnetoresistance of the whole sample is similar to the anisotropic magnetoresistance, because the resistance of the two microscale thin film ferromagnetic electrodes is much higher than that of the local nano-region in the middle of the samples. Comparing the experimental results for the thin film ferromagnetic nanoconstrictions and the thin ferromagnetic film reveals that the magnetoresistance of the local nano-region in the middle of the sample is much higher than that of the two microscale thin film ferromagnetic electrodes attached to it. | CHENG Hao YANG Wei LIU Hong WANG LingJiang | 2012 | Chinese Science Bulletin2012，57，5： | 2 |
| 11 | Thermal comfort in winter incorporating solar radiation effects at high altitudes and performance of improved passive solar design-Case of Lhasa显示文摘The solar incidence on an indoor environment and its occupants has significant impacts on indoor thermal comfort.It can bring favorable passive solar heating and can result in undesired overheating(even in winter).This problem becomes more critical for high altitudes with high intensity of solar irradiance,while received limited attention.In this study,we explored the specific overheating and rising thermal discomfort in winter in Lhasa as a typical location of a cold climate at high altitudes.First,we evaluated the thermal comfort incorporating solar radiation effect in winter by field measurements.Subsequently,we investigated local occupant adaptive responses(considering the impact of direct solar irradiance).This was followed by a simulation study of assessment of annual based thermal comfort and the effect on energy-saving potential by current solar adjustment.Finally,we discussed winter shading design for high altitudes for both solar shading and passive solar use at high altitudes,and evaluated thermal mass shading with solar louvers in terms of indoor environment control.The results reveal that considerable indoor overheating occurs during the whole winter season instead of summer in Lhasa,with over two-thirds of daytime beyond the comfort range.Further,various adaptive behaviors are adopted by occupants in response to overheating due to the solar radiation.Moreover,it is found that the energy-saving potential might be overestimated by 1.9 times with current window to wall ratio requirements in local design standards and building codes due to the thermal adaption by drawing curtains.The developed thermal mass shading is efficient in achieving an improved indoor thermal environment by reducing overheating time to an average of 62.2% during the winter and a corresponding increase of comfort time. | Lingjiang Huang Jian Kang | 2021 | Building Simulation2021，14，6： | 1 |
| 12 | Performance analysis of GLRT-based adaptive detector for distributed targets in compound-Gaussian clutter显示文摘 | SHUAI Xiaofei KONG Lingjiang YANG Jianyu | 2010 | Signal Processing2010，90，1： | 1 |
| 13 | Adaptive detector design of MIMO radar with unknown covariance matrix显示文摘The problem of detecting signal with multiple input mul-tiple output (MIMO) radar in correlated Gaussian clutter dominated scenario with unknown covariance matrix is dealt with. The gen-eral MIMO model, with widely separated sub-arrays and co-located antennas at each sub-array, is adopted. Firstly, the generalized likelihood ratio test (GLRT) with known covariance matrix is ob-tained, and then the Rao and Wald detectors are devised, which have proved that the Rao and Wald test coincide with GLRT detec-tor. To make the detectors fully adaptive, the secondary data with signal-free will be collected to estimate the covariance. The per-formance of the proposed detector is analyzed, however, it is just ancillary. A thorough performance assessment by several numer-ical examples is also given, which has considered the sense with co-located antennas configure of transmitters and receivers array. The results show that the performance the proposed adaptive de-tector is better than LJ-GLRT, and the loss can be acceptable in comparison to their non-adaptive counterparts. | Lingjiang Kong Guolong Cui Xiaobo Yang Jianyu Yang | 2010 | Journal of Systems Engineering and Electronics2010，21，6： | 1 |
| 14 | High- frequency rTMS treatment increases white matter FA in the left middle frontal gyrus in young patients with treatment-re- sistant depression 显示文摘 | Hongjun Peng Huirong Zheng Lingjiang Li | 2012 | Journal of Affective Disorders2012，136，： | 1 |
| 15 | CP-based MIMO OFDM radar IRCI free range reconstruction using real orthogonal designs显示文摘In this paper, we propose a range reconstruction method for a frequency-band shared multipleinput multiple-output(MIMO) orthogonal frequency-division multiplexing(OFDM) radar with sufficient cyclic prefix(CP) by using real orthogonal designs. Compared with the application of complex orthogonal designs in our previous work, the application of real orthogonal designs can significantly reduce the number of the all-zero-valued pulses in a coherent processing interval(CPI) for each transmitter and increase the efficiency of radar transmitters. Meanwhile, it still maintains the advantages of full spatial diversity without inter-range-cell interference(IRCI). We also apply the rate-1 real orthogonal designs for different numbers of transmitters and pulses for range reconstruction without any idleness of radar transmitters. Simulation results are presented to illustrate the performances of the OFDM pulse design and the CP-based MIMO OFDM radar using real orthogonal designs. | Tianxian ZHANG Xiang-Gen XIA Lingjiang KONG | 2017 | Science China(Information Sciences)2017，60，2： | 1 |
| 16 | A- daptive Detection in Compound-Gaussian Clutter with In- verse Gaussian Texture显示文摘 | CHEN Sijia KONG Lingjiang and YANG Jianyu | 2013 | Progress in Electromagnetics Research M2013，，28： | 1 |
| 17 | Development and validetion of the generic quality of life inventory in China显示文摘 | Derson Yang Hao Wei | 1997 | Quality of Life Research1997，6，4： | 1 |
| 18 | The reationship between objective life status and subjective life satisfaction with quality of life显示文摘 | Derson Yang Hao Wei | 1998 | Behavioral Medicine1998，23，2： | 1 |
| 19 | Progress in immunopharmacologic study of Ypingfeng Powder 显示文摘 | Hong Lingjiang Xin Hongtao | 2000 | Chinese Journal of Integrated Traditional and Western Medici2000，6，2： | 1 |
| 20 | Performance analysis of GLRT-based adaptive detector for distributed targets in compound-Gaussian clutter 显示文摘 | Shuai Xiaofei Kong Lingjiang Yang Jianyu | 2010 | Signal Processing2010，90，： | 1 |
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