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| 1 | Analyses of prognostic indices of chronic liver failure caused by hepatitis virus显示文摘AIM: To analyze the related indices about the prognosesof chronic liver failure caused by hepatitis virus.METHODS: Retrospectively reviewed 320 cases of chronic liver failure caused by hepatitis viruses. An improved group and an ineffective group (IG) were made to compare and analyze their clinical manifestations, laboratory examination indices and complications. Logistic regression was also carried out. RESULTS: There were significant differences (P<0.05) between the improved group and the IG upon such indices as age, bilirubin, prothrombin time, albumin, alpha fetoprotein, the size of liver and complications (P<0.05). The regression formula was as follows: P = 1/(1+e-y)(y= 1.7262-0.0948X1+2.9846X2+0.6992X3+ 1.6019X4+2.0398X5). (Note: X1-Prothrombin activity; X2-digestive tract hemorrhage; X3-hepatic encephalopathy; X4-hepatorenal syndrome; X5-pulmonary infection.).CONCLUSION: Laboratory examination such as bilirubin, prothrombin time and alpha fetoprotein can be regarded as indices of the prognoses of chronic liver failure caused by hepatitis. Moreover, the regression equation can evaluate prognoses more comprehensively and direct our treatments. | Xiao-MaoLi LinMa Yue-BoYang Zhong-JieShi Shui-ShengZhou | 2005 | World Journal of Gastroenterology2005，11，18： | 14 |
| 2 | Pregnant woman with fulminant hepatic failure caused by hepatitis B virus infection: A case report显示文摘AIM: To report the experience in successfully treating pregnant women with severe hepatitis.METHODS: Comprehensive medical treatments were performed under strict monitoring.RESULTS: Pregnant woman with severe hepatitis was successfully rescued.CONCLUSION: Vital measures taken in the treatment of pregnant women with severe hepatitis include termination of the pregnancy at a proper time and control of various complications, such as disseminated intravascular coagulation (DIC), hepatorenal syndrome, hepatic encephalopathy and infection. | Yue-BoYang Xiao-MaoLi Zhong-JieShi LinMa | 2004 | World Journal of Gastroenterology2004，10，15： | 10 |
| 3 | Abnormal Alterations of Cortical Thickness in 16 Patients with Type 2 Diabetes Mellitus: A Pilot MRI Study显示文摘这研究的目的是调查服的外皮的厚度的目的用一个整个大脑在类型 2 糖尿病 mellitus ( T2DM )变化基于大脑印射系统的外皮的厚度磁性的回声成像( MRI ) .Methods 高度分辨率三维的T1加权的快宠坏的坡度记起的回响先生图象从 16 个病人被获得与 T2DM ,以及从 16 正常控制。外皮的厚度印射的整个大脑被产生,并且每个大脑区域的外皮的厚度用由 Freesurfer 软件的一个自动化标记的系统根据兴趣(ROI ) 的旋转基于的区域是计算的。我们作为 covariates 由协变性的分析在每个大脑区域把吝啬的外皮的厚度与年龄和性别作比较。在整个大脑上的外皮的厚度的地区性的差别被吝啬的外皮的厚度分析显示出的基于表面的外皮的 thickness.Results 的分析比较在有 T2DM 的病人的双边的大脑(左:2. | ZhiyeChen XiujuanZang MengqiLiu MengyuLiu JinfengLi ZhaoyanGu LinMa | 2017 | Chinese Medical Sciences Journal2017，32，2： | 3 |
| 4 | Two New Sequiterpenoids from Helicteres angustifolia显示文摘A new sesquiterpenoid lactone, 3,6,9-trimethyl-pyrano[2,3,4-de]chromen-2-one (1) and a novel sesquiterpenoid quinone, 6-[2-(5-acetyl-2,7-dimethyl-8-oxo-bicyclo[4.2.0]octa-1,3,5- trien-7-yl)-2-oxo-ethyl]-3,9-dimethylnaphtho[1,8-bc]pyran-7,8-dione (2) together with a known perezone (3) were isolated from the roots of Helicteres angustifolia. The structures were elucidated as mainly on the basis of 1D and 2D NMR spectroscopic data. | XinDongGUO ZhiShuHUANG YaDanBAO LinKunAN LinMA LianQuanGU | 2005 | Chinese Chemical Letters2005，16，1： | 3 |
| 5 | Brain-derived neurotrophic factor promotes pulmonary artery endothelial cells proliferation and inflammatory cytokines secretion显示文摘Pulmonary hypertension(PH)is a progressive disease caused by pathological vascular remodeling of arterial vessels and elevated pulmonary artery pressure that result in pressure overload of the heart right ventricle eventually causing its failure.Pulmonary artery endothelial cells(PAECs)dysfunction and local inflammation play important roles in the development of PH.Recent studies suggested that neurotrophin growth factors,particularly brain-derived neurotrophic factor(BDNF)and its high-affinity receptor TrkB,were significantly increased in the PAECs under the hypoxia condition.The aim of this study was to explore the possible effects of BDNF on PAECs. | Jin Haifeng Guo Linma Jiang Yang Ma Yong Shen Lei Yao Lijie | 2021 | 解剖学杂志2021，44，S01： | 1 |
| 6 | Diagnostic value of minimum apparent diffusion coefficient values in prediction of neuroepithelial tumor grading显示文摘 | ZhiyeChen LinMa XinLou ZhenhongZhou | 2010 | J Magn Reson Imaging2010，，6： | 1 |
| 7 | Synthesis and Characterization of Novel Multifunctional Acylthiourea Polymers显示文摘Several thiourea polymers have been synthesized through the reaction of diamine with 1, 4- or 1, 3- benzenedicarbonyl chloride and ammonium thiocyanate by solid-liquid phase transfer catalysis of polyethylene glycol-400 (PEG-400). The polymers were characterized and identified by elemental analysis, IR, 1HNMR and GPC. The multifunctional polymers have potential value as an ideal support for immobilized enzymes. | XuePuMAO JinFengHUANG ZhiFangDUAN ZhiYunDU ZhiShuHUANG LinMA LianQuanGU | 2005 | Chinese Chemical Letters2005，16，5： | 1 |
| 8 | Effect of crude fraclions of psoraleacorylifolia seed extract on bone calcification显示文摘 | Miura H Nishida H Linma M | 1996 | Plata Med1996，62，2： | 1 |
| 9 | Amphiregulin Antisense RNA Delivered by Adnovirus Suppresses Growth of Breast Cancer Cells In Vitro and In Vivo显示文摘OBJECTIVE To investigate the therapeutic potential of amphiregulin antisense RNA delivered by adenoviral vector in a human breast cancer model.METGODS Human amphiregulin cDNA was subcloned in the opposite orientation to the cytomegaloviral promoter and inserted into an El/E3-deleted type 5 adenoviral vector to obtain an AdA4 construct which expresses amphiregulin antisense mRNA. Both in vitro and in vivo antiproliferative effects of the antisense RNA were studied by infecting transformed human breast epithelial NS2T2A1 cells and tumors.RESULTS Amphiregulin protein expression was inhibited dramatically in the NS2T2A1 cells after infection with AdA4. The in vitro cell growth was inhibited significantly at day 4 post-AdA4 infection compared with control empty virus AdCl at a MOI of 200 and 400 pfu/cell to 69.3% and 49.8%, respectively (P<0.02, P<0.005). After 3 intra-tumoral injections of 10^9 pfu AdA4, tumor volumes were reduced to 40.6% of that of the control group at day 35 (P<0.005).CONCLUSION The transfer of amphiregulin RNA antisense by adenoviral vector is effective for amphiregulin targeting strategy, leading to an inhibition of in vitro cell proliferation and in vivo tumor growth in this breast cancer model. | LinMa VoahangyRandrianarison FabienCalvo | 2005 | Chinese Journal of Clinical Oncology2005，2，2： | 0 |
| 10 | Trigeminal Ganglioneuroma in the Middle-posterior Cranial Fossa: a Case Report显示文摘GANGLIONEUROMA is considered as the most mature and noninvasive form of neuroblastic tumors.It derives from neural crest cells,and can arise from wherever sympathetic tissue exists,1 including neck,posterior mediastinum,adrenal gland,retroperitoneum and pelvis.The two most common locations for this tumor are retroperitoneum and | TingWang LinMa Xin Lou BoBu | 2017 | Chinese Medical Sciences Journal2017，32，2： | 0 |
| 11 | The Effect of Combining Fast Neutron and Photon Irradiation on the Human Osteosarcoma OS-732 Cell Line显示文摘OBJECTIVE To determine the lethal effect of combining fast neutron with photon radiation on the OS-732 cell line. METHODS We examined the effect of irradiation by fast neutrons, photons and a mixed beam (fast neutrons plus photons) on the lethality and colony forming ability of the OS-732 cell line at different times. RESULTS Following a single irradiation close, the lethality was markedly strong at 24, 48 and 72 h in the group treated with fast neutrons alone and in the mixed beam group in which there was a high proportion of fast neutrons. CONCLUSION The lethal effect of a fast neutron and mixed beam with a high proportion of fast neutrons on the OS-732 cell line is highly significant. These studies provide guidance for the clinical application of fast neutrons for osteosarcoma treatment. | LinchunFeng LinMa JingxiangHuang DongYang YingxuanWang MingxueSun JinhuaTang WeikeChang ChengxiangLiu | 2005 | Chinese Journal of Clinical Oncology2005，2，3： | 0 |
| 12 | Synthesis of New Benzoimidazole Derivatives显示文摘The reactions of cryptotanshinone and tanshinone IIA with cadaverine and putrescine were investigated. Six new compounds, four with imidazole functional groups and two with oxazole groups, were obtained. The possible reaction mechanism was proposed. | LinKunAN XianZhangBU ZhiShuHUANG LinMA LianQuanGU AlbertS.C.CHAN YueMingLI | 2005 | Chinese Chemical Letters2005，16，1： | 0 |
| 13 | Analysis of the Survival Rate with Cervical Cancer Using ^137Cs and ^192Ir Aftedoading Brachytherapy显示文摘OBJECTIVE To analyze and compare the survival rate for stages Ⅱ and Ⅲ cervical cancer treated by external irradiation plus ^137Cs or ^192Ir. METHODS The patients with cervical cancer were treated by external irradiation plus ^137Cs (group A, 427 patients) or plus ^192Ir (group B, 156 patients). There were 170 stage Ⅱ cases and 413 stage Ⅲ cases. The number of cancer types were as follows: squamous cell carcinoma, 524; adenocarcinoma, 34; and adenosquamous cell carcinoma, 25. The two groups received the same external irradiation using 8 or 10 MV of X-ray. After the whole pelvis received 25-35 Gy, the focus was given a total of 45-55 Gy by four divided fields. Intracavitary irradiation was performed with one fraction of 6-7 Gy in reference dose at A point every week and a total dose of 40-60 Gy with 6-8 fractions for group A; every fraction of 5-6 Gy in reference dose of A point and total dose of 30-42 Gy with 5-7 fractions for group B.RESULTS The 5-year survival rate of stage Ⅱ and Ⅲ, and total were 82.9%, 62.2%, and 67.2% for group A respectively and 85.1%, 61.5% and 69.2% for group B respectively. There were significant differences between stage Ⅱ and Ⅲ in each group (P< 0.05) but there were no differences in the 5-year survival rate between the two groups (P> 0.05). The late complications of the therapy were rectitis and urocystitis and with an incidence rate of 7.3% and 6.3% for group A and 9.6% and 9.0% for group B (P> 0.05). CONCLUSION The long-term survival rate and complications of stages Ⅱ and Ⅲ cervical cancer are similar when treated with external irradiation plus ^137Cs or plus ^192Ir. | GuixioZhou GuoxiongChen DemeiMa JianpingSun LinMa | 2004 | Chinese Journal of Clinical Oncology2004，1，2： | 0 |
| 14 | Integrating Parallelizing Compilation Technologies for SMP Clusters显示文摘In this paper, a source to source parallelizing complier system, AutoPar, is presentd. The system transforms FORTRAN programs to multi-level hybrid MPI/OpenMP parallel programs. Integrated parallel optimizing technologies are utilized extensively to derive an effective program decomposition in the whole program scope. Other features such as synchronization optimization and communication optimization improve the performance scalability of the generated parallel programs, from both intra-node and inter-node. The system makes great effort to boost automation of parallelization.Profiling feedback is used in performance estimation which is the basis of automatic program decomposition. Performance results for eight benchmarks in NPB1.0 from NAS on an SMP cluster are given, and the speedup is desirable. It is noticeable that in the experiment, at most one data distribution directive and a reduction directive are inserted by the user in BT/SP/LU. The compiler is based on ORC, Open Research Compiler. ORC is a powerful compiler infrastructure, with such features as robustness, flexibility and efficiency. Strong analysis capability and well-defined infrastructure of ORC make the system implementation quite fast. | Xiao-BingFeng LiChen Yi-RanWang Xiao-MiAn LinMa Chun-LeiSang Zhao-QingZhang | 2005 | Journal of Computer Science & Technology2005，20，1： | 0 |
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