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| 1 | 曹雪涛院士科研团队论文荣膺中国百篇最具影响国际学术论文--长链非编码RNA1nc-DC通过STAT3调控人DC的分化和功能显示文摘树突状细胞(DC)是免疫系统中重要的抗原提呈细胞,其成熟和功能状态决定着免疫应答的走向和强度。哺乳动物基因组能够转录产生大量的长链非编码RNA(long noncoding RNA,IncRNA),其在免疫系统中的功能还知之甚少。
曹雪涛院十科研团队王品副教授课题组采用了转录组芯片二代测序高通量筛选方法、RNA-pulldown、ChIP-seq等技术展开了对IncRNA在DC分化和功能中作用的研究,发现并鉴定了特异性高表达于DC的1ncRNA,命名为1nc-DC,其可通过抑制STAT3去磷酸化,从而促进DC分化和功能。该研究成果发表于Science杂志[2014,344(6181):310-313],并于2015年12月被评为“中国百篇最具影响国际学术论文”。 | wang p xue y han y lin l wu c xu s jiang z xu j liu q cao x | 2016 | 中国肿瘤生物治疗杂志2016，23，1： | 10 |
| 2 | A concise survey of scheduling with time-dependent processing times显示文摘 | Cheng T C E Ding Q Lin B M T | 2004 | European Journal of Operational Research2004，152，： | 1 |
| 3 | Delay-range-dependent stability for systems with time-varying delay显示文摘 | He Y Wang Q G Lin C | 2007 | Automatica2007，43，： | 1 |
| 4 | Adhesion mechanisms of the mussel ioot proteins mfp-1 and mfp-3 显示文摘 | Lin Q Gourdon D Sun C | 2007 | Proc Natl Acad Sci US A2007，104，10： | 1 |
| 5 | Evaluating Carbon Dioxide Emissions in International Trade of China显示文摘 | Lin B Q Sun C W | 2010 | Energy Policy2010，38，： | 1 |
| 6 | Heterotrimeric G proteins regulate nitrogen-use efficiency in rice 显示文摘 | Sun H Y Qian Q Wu K Luo J J Wang S S Zhang C W Ma Y F Liu Q Huang X Z Yuan Q B Han R X Zhao M Dong G J Guo L B Zhu X D Gou Z H Wang W Wu Y J Lin H X Fu X D | 2014 | Nature Genetics2014，46，4： | 1 |
| 7 | Effect of pokeweed antiviral protein (PAP) on the infection of plant virus 显示文摘 | Chen Z C White R F Antoniw J F and Lin Q | 1991 | Plant Pathology1991，40，： | 1 |
| 8 | Hydrogen suifide attenuates epithelial-mesenchymal transition of human alveolar epithelial cells显示文摘 | FANG L P LIN Q TANG C S | 2010 | Pharmacol Res2010，6，4： | 1 |
| 9 | Amorphous TiO2 films with high refractive index deposited by pulsed bias arc ion plating显示文摘 | Zhang M Lin G Q Dong C | 2007 | Surface and Coatings Technol2007，201，1617： | 1 |
| 10 | Consumer information search when making investment decisions 显示文摘 | Lin Q C Lee J | 2004 | Financial Services Review2004，13，4： | 1 |
| 11 | An improvement on multivariable PID controller design via iterative LMI approach 显示文摘 | Lin C Wang Q G Lee T H | 2004 | Auto- matica2004，40，3： | 1 |
| 12 | Characterization of a novel envelope protein(VP281)of shrimp white spot syndrome virus by mass spectrometry显示文摘 | HUANG C ZHANG X LIN Q | | 0，，： | 1 |
| 13 | Phase constituents and microstructure of laser cladding Al2O3/Ti3Al reinforced ceramic layer on titanium alloy显示文摘 | Li J N Chen C Z Lin Z Q | | 0，，14： | 1 |
| 14 | Numerical simulations on relationships between gas velocity and overpressure of gas explosions in ducts显示文摘 | Zhu C J Lin B Q Hong Y D | 2013 | Disaster Advances2013，6，1： | 1 |
| 15 | A concise survey of scheduling with time-dependent processing times显示文摘 | Cheng T C E Ding Q Lin B M T | 2004 | European Journal of Operational Research2004，152，： | 1 |
| 16 | Robust normalization and stability of uncertain descriptor system with norm bounded perturbations显示文摘 | LIN C WANG Q G LEE T H | 2005 | IEEE Transactions on Automatic Control2005，50，4： | 1 |
| 17 | The isolation and characterization of Pik,a rice blast resistance gene which emerged after rice domestication显示文摘 | Zhai C Lin F Dong Z Q | 2010 | New Phytologist2010，189，1： | 1 |
| 18 | The Synthesis of Ni-Zn Ferrite by Wet Method显示文摘 | Lin C H Chen S Q | 1983 | Chinese J Mater Sci1983，14，1： | 1 |
| 19 | A novel pathway for mammary epithelial cell invasion induced by the helix - loop - helix protein显示文摘 | Desprez PY Lin C Q Thomasset N | 1998 | Cell Biol1998，18，： | 1 |
| 20 | A concise survey of scheduling with time-dependent processing times显示文摘 | Cheng T C E Ding Q Lin B M T | 2004 | European Journal of Operational Research2004，152，1： | 1 |
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