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| 1 | Malate transported from chloroplast to mitochondrion triggers production of ROS and PCD in Arabidopsis thaliana显示文摘规划房间死亡(PCD ) 是一个基本生物过程。在马赛克死亡 1 的缺乏(MOD1 ) ,质体局部性的 enoyl-ACP reductase,导致反应的氧种类(ROS ) 和 PCD 的累积,它能被 mitochondrial 建筑群压制我变化,从叶绿体显示一个信号到线粒体。然而,这个信号尚待被阐明。在这研究,通过克隆并且分析一系列 mod1 suppressors,我们揭示调整 mitochondrial ROS 和扳机 PCD 的产生的一条全面细胞器通讯小径。我们证明在 PLASTIDIAL NAD 依赖的 MALATE 脱氢酶(plNAD-MDH ) 的变化, chloroplastic DICARBOXYLATE TRANSPORTER 1 (DiT1 ) 并且(mMDH1 ) MITOCHONDRIAL MALATE 脱氢酶 1 能各在 mod1 救 ROS 累积和 PCD 显型,经由 malate 梭从叶绿体表明直接通讯到线粒体。进一步的研究证明这些元素在不同光周期条件下面在氧化还原作用动态平衡和植物生长起关键作用。而且,我们表明 ROS 水平和 PCD 显著地在房间,它能是戏剧性地稀释了由的对待 malate 的 HeLa 被增加人的基因 MDH2 击倒, Arabidopsis mMDH1 的 ortholog。这些结果揭开在植物和动物系统的一条保存导致 malate 的 PCD 小径,革命化我们在细胞器之间的通讯的理解。 | Yannan Zhao Lilan Luo Jiesi Xu Peiyong Xin Hongyan Guo Jian Wu Lin Bai Guodong Wang Jinfang Chu Jianru Zuo Hong Yu Xun Huang Jiayang Li | 2018 | Cell Research2018，28，4： | 24 |
| 2 | Regulation of mitochondrial NAD pool via NAD^+ transporter 2 is essential for matrix NADH homeostasis and ROS production in Arabidopsis显示文摘Reactive oxygen species(ROS) play a crucial role in numerous biological processes in plants, including development, responses to environmental stimuli, and programmed cell death(PCD). Deficiency in MOSAIC DEATH 1(MOD1), a plastid-localized enoyl-ACP reductase essential for de novo fatty acid biosynthesis in Arabidopsis thaliana, leads to the increased malate export from chloroplasts to mitochondria, and the subsequent accumulation of mitochondria-generated ROS and PCD. In this study, we report the identification and characterization of a mod1 suppressor, som592. SOM592 encodes mitochondrion-localized NAD^+ transporter 2(NDT2). We show that the mitochondrial NAD pool is elevated in the mod1 mutant. The som592 mutation fully suppressed mitochondrial NADH hyper-accumulation, ROS production, and PCD in the mod1 mutant, indicating a causal relationship between mitochondrial NAD accumulation and ROS/PCD phenotypes. We also show that in wild-type plants, the mitochondrial NAD+uptake is involved in the regulation of ROS production in response to continuous photoperiod. Elevation of the alternative respiration pathway can suppress ROS accumulation and PCD in mod1, but leads to growth restriction. These findings uncover a regulatory mechanism for mitochondrial ROS production via NADH homeostasis in Arabidopsis thaliana that is likely important for growth regulation in response to altered photoperiod. | Lilan Luo Yajun He Yannan Zhao Qian Xu Jian Wu Haiyan Ma Hongyan Guo Lin Bai Jianru Zuo Jian-Min Zhou Hong Yu Jiayang Li | 2019 | Science China(Life Sciences)2019，62，8： | 5 |
| 3 | Electrochemical degradation of perfluorooctanoic acid (PFOA) by Ti/SnO 2 –Sb, Ti/SnO 2 –Sb/PbO 2 and Ti/SnO 2 –Sb/MnO 2 anodes显示文摘 | Hui Lin Junfeng Niu Shiyuan Ding Lilan Zhang | 2012 | Water Research2012，，7： | 2 |
| 4 | Research into Development Dilemmas of MOOC in China' s Higher Education and Its Countermeasures显示文摘The Massive Open Online Courses( MOOC) originated in Europe and America has been a new channel obtaining know ledge and an important learning mode in the age of big data. The development of MOOC brings about far- reaching impact on sharing and constructing the high quality education resources in the w orld,w hich may present great challenges to traditional teaching mode. Considering China's higher education environment and MOOC 's particular characteristics,this paper summarizes the development dilemmas of MOOC in China's higher educational environment and discusses the countermeasures as w ell as finds a suitable w ay for the development of informatization education. | Zhai Xuesong Lin Lilan | 2014 | 学术界2014，，3： | 2 |
| 5 | Effective shape-controlled synthesis of gallium selenide nanosheets by vapor phase deposition显示文摘The controlled synthesis of large and uniform gallium selenide(GaSe)crystals is crucial for its various applications based on the attractive properties of this emerging material.In this work,vapor phase growth of high-quality monolayer GaSe nanosheets with multiple shape and size is achieved by tuning the Ga/GaSe ratio in the precursor.A theoretical model based on density functional theory calculations and kinetic Wulff construction theory describe the observed shape evolution of the GaSe nanosheets.Results show that the Ga/Se ratio plays a critical role in the evolution of the domain shape and size.Moreover,the as-grown GaSe nanosheets show improved performance with photoresponse time less than 0.7 ms and responsibility up to 3,000 AW.This study presents a previously unexplored strategy for the controlled growth of two-dimensional(2D)GaSe nanosheets for promising applications in next-generation optoelectronics. | Lilan Tan Qingbo Liu Yufeng Ding Xiaogang Lin Wei Hu Meng-Qiu Cai Hong Zhou | 2020 | Nano Research2020，13，2： | 2 |
| 6 | Electrochemical degradation of perfluorooctanoic acid (PFOA) by Ti/SnO 2 –Sb, Ti/SnO 2 –Sb/PbO 2 and Ti/SnO 2 –Sb/MnO 2 anodes显示文摘 | Hui Lin Junfeng Niu Shiyuan Ding Lilan Zhang | 2012 | Water Research2012，，7： | 1 |
| 7 | Examining effective ways of encouraging students to speak in class显示文摘 | | 2003 | Foreign Language Teaching and Research Press2003，26，1： | 1 |
| 8 | Sonar Image Target Detection for Underwater Communication System Based on Deep Neural Network显示文摘Target signal acquisition and detection based on sonar images is a challenging task due to the complex underwater environment.In order to solve the problem that some semantic information in sonar images is lost and model detection performance is degraded due to the complex imaging environment,we proposed a more effective and robust target detection framework based on deep learning,which can make full use of the acoustic shadow information in the forward-looking sonar images to assist underwater target detection.Firstly,the weighted box fusion method is adopted to generate a fusion box by weighted fusion of prediction boxes with high confidence,so as to obtain accurate acoustic shadow boxes.Further,the acoustic shadow box is cut down to get the feature map containing the acoustic shadow information,and then the acoustic shadow feature map and the target information feature map are adaptively fused to make full use of the acoustic shadow feature information.In addition,we introduce a threshold processing module to improve the attention of the model to important feature information.Through the underwater sonar dataset provided by Pengcheng Laboratory,the proposed method improved the average accuracy by 3.14%at the IoU threshold of 0.7,which is better than the current traditional target detection model. | Lilan Zou Bo Liang Xu Cheng Shufa Li Cong Lin | 2023 | Computer Modeling in Engineering & Sciences2023，137，12： | 0 |
| 9 | Information Technology and the Construction of New English Teaching Model in China显示文摘The role that information technology plays in foreign language teaching is no longer confined to assisting teachers to impart knowledge. This paper aims at construction of new English teaching model based on information technology. The author adopted ethnographic research to observe 8 classes and the findings of this study suggest that until frontline teachers deepen their understanding of information technology and change their philosophy of teaching can a successful implementation of the new teaching model be ensured. | Zhang Weihong Lin Lilan | 2015 | 学术界2015，，2： | 0 |
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