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| 1 | The Chromosome-Level Reference Genome of Tea Tree Unveils Recent Bursts of Nonautonomous LTR Retrotransposons in Driving Genome Size Evolution显示文摘Dear Editor,The tea tree Camellia sinensis,a member of the genus Camellia in the Theaceae family,includes two major cultivated varieties,C.sinensis var.assamica(CSA\Assam type)and C.sinensis var.sinensis(CSS;Chinese type)(Ming and Bartholomew,2007).Due to the high economic importance of the tea tree,considerable efforts have been made to explore genetic basis of the biosynthesis of natural metabolites that determine health benefits and diverse tea flavors(Shi et al.,2011;Li et al.,2011;Li et al.,2015;Xia et aL,2017;Liu et al.,2019). | Qun-Jie Zhang Wei L i Kui Li Hong Nan Cong Shi Yun Zhang Zhang-Yan Dai Yang-Lei Lin Xiao-Lan Yang Yan Tong Dan Zhang Cui Lu Li-Ying Feng Chen-Feng Wang Xiao-Xin Liu Jian-An Huang Wen-Kai Jiang Xing-Hua Wang Xing-Cai Zhang Evan E.Eichler Zhong-Hua Liu and Li-Zhi Gao | 2020 | Molecular Plant2020，13，7： | 27 |
| 2 | Comparative effectiveness of i-SCAN^(TM) and high-definition white light characterizing small colonic polyps显示文摘AIM:To evaluate accuracy of in vivo diagnosis of adenomatous vs non-adenomatous polyps using i-SCAN digital chromoendoscopy compared with high-definition white light.METHODS:This is a single-center comparative effectiveness pilot study.Polyps(n = 103) from 75 averagerisk adult outpatients undergoing screening or surveillance colonoscopy between December 1,2010 and April 1,2011 were evaluated by two participating endoscopists in an academic outpatient endoscopy center.Polyps were evaluated both with high-definition white light and with i-SCAN to make an in vivo prediction of adenomatous vs non-adenomatous pathology.We determined diagnostic characteristics of i-SCAN and highdefinition white light,including sensitivity,specificity,and accuracy,with regards to identifying adenomatous vs non-adenomatous polyps.Histopathologic diagnosis was the gold standard comparison.RESULTS:One hundred and three small polyps,detected from forty-three patients,were included in the analysis.The average size of the polyps evaluated in the analysis was 3.7 mm(SD 1.3 mm,range 2 mm to 8 mm).Formal histopathology revealed that 54/103(52.4%) were adenomas,26/103(25.2%) were hyperplastic,and 23/103(22.3%) were other diagnoses include 'lymphoid aggregates','non-specific colitis,' and 'no pathologic diagnosis.' Overall,the combined accuracy of endoscopists for predicting adenomas was identical between i-SCAN(71.8%,95%CI:62.1%-80.3%) and high-definition white light(71.8%,95%CI:62.1%-80.3%).However,the accuracy of each endoscopist differed substantially,where endoscopist A demonstrated 63.0% overall accuracy(95%CI:50.9%-74.0%) as compared with endoscopist B demonstrating 93.3% overall accuracy(95%CI:77.9%-99.2%),irrespective of imaging modality.Neither endoscopist demonstrated a significant learning effect with i-SCAN during the study.Though endoscopist A increased accuracy using i-SCAN from 59%(95%CI:42.1%-74.4%) in the first half to 67.6%(95%CI:49.5%-82.6%) in the second half,and endoscopist B decreased accuracy using i-SCAN from 100%(95%CI:80.5%-100.0%) in the first half to 84.6%(95%CI:54.6%-98.1%) in the second half,neither of these differences were statistically significant.CONCLUSION:i-SCAN and high-definition white light had similar efficacy predicting polyp histology.Endoscopist training likely plays a critical role in diagnostic test characteristics and deserves further study. | Johanna L Chan Li Lin Michael Feiler Andrew I Wolf Diana M Cardona Ziad F Gellad | 2012 | World Journal of Gastroenterology2012，18，41： | 3 |
| 3 | 欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。 | 刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F | 2018 | 中华高血压杂志2018，26，4： | 3 |
| 4 | Vital staining of cardiac myocytes during embryonic stem cell cardiogenesis in vitro显示文摘 | LIN W I SAMUELSON L C | 1996 | Circ Res1996，78，4： | 1 |
| 5 | An integrated reverse engineering approach to reconstructing free- form surfaces显示文摘 | CHEN L C LIN G C I | 1997 | CIMS1997，10，1： | 1 |
| 6 | A secure nonrepudiable threshold proxy signature scheme with known signers显示文摘 | Hwang M S Lin I C Lu E J L | 2000 | International Journal of Informatica2000，11，2： | 1 |
| 7 | The red cell immune system 显示文摘 | SIEGEL I LIN T L GIEICHER | 1981 | Lancet1981，12，2： | 1 |
| 8 | Expression of angiopoietins and vascular endothelial growth factors and their clinical significance in acute myeloid leukemia显示文摘 | Hou H A Chou W C Lin L I | 2008 | Leuk Res2008，32，6： | 1 |
| 9 | Ganoderiol F,a ganoderma triterpene,induces senescence in hepatoma HepG2 cells显示文摘 | CHANG U M LI C H LIN L I | 2006 | Life Sci2006，79，12： | 1 |
| 10 | Composition of polyphenol in fresh tea leaves and associations of their oxygen-radical-absorbing capacity with antipro liferative actions in fibroblast cells显示文摘 | LIN Y L JUAN I M CHEN Y L eT al | 1996 | J Agile Food Chem1996，44，： | 1 |
| 11 | Renal Cavernous Hemangioma: a case report 显示文摘 | Huang C L Lin I L Chen W P | 2009 | Chin J Radiol2009，34，： | 1 |
| 12 | Anticancer activity of botanical alkyl hydroquinones attributed to topoisomerase II poisoning显示文摘 | Huang C P Fang W H Lin L I | 2008 | Toxicology and Applied Pharmacology2008，227，3： | 1 |
| 13 | Effects of transglutaminase treatment on the thermal properties of soy protein isolates显示文摘 | Chuan-He Tang Zhong Chen Lin l i el al | 2006 | Food Research International2006，，39： | 1 |
| 14 | HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen显示文摘 | Li N Zhao D Kirschbaum M Zhang C Lin C L Todorov I | 2008 | Proc Natl Acad Sci USA2008，105，： | 1 |
| 15 | The red cell immune system显示文摘 | Sieael I Lin T L Gleichan N | 1981 | Lancet1981，2，： | 1 |
| 16 | Cyber Java Monopoly:Game-based ap- proach of collaborative programming language learning显示文摘 | Hsiao I H Lin Y L | 2008 | 2008，，： | 1 |
| 17 | Haemolymph parameters of Pacific white shrimp (Litopenaeus vannamei) infected with Taura syndrome virus显示文摘 | Song Y L Yu C I Lien T W Huang C C Lin M N | 2003 | Fish Shellfish Immunol2003，14，4： | 1 |
| 18 | A Concordance Correlation Coefficient to Evaluate Repro-ducibility显示文摘 | Lin L I | 1989 | Biometrics1989，45，1： | 1 |
| 19 | Anti-platelet aggregation constituents from Gynura elliptica显示文摘 | Lin W Y Teng C M Tsai I L | 2000 | Phytochemistry2000，53，8： | 1 |
| 20 | Synthesis of M acM illan catalyst tailored with ionic liq u id as a recoverable catalystfor asymmetric D iels-A lder reaction显示文摘 | Nino A D B o rto lin i O M aiuolo L e t a l | 2011 | Tetrahedron L e tt2011，52，： | 1 |
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