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| 1 | Hydrocarbon accumulation characteristics of beachbar sandstones in the southern slope of the Dongying Sag, Jiyang Depression, Bohai Bay Basin, China显示文摘A number of beach-bar sandstone reservoir beds are developed in the upper fourth member of the Eocene Shahejie Formation(Ess4) on the southern slope of the Dongying Sag. Based on the analysis of seismic and logging data, with characterization and petrographic studies of core and cutting samples, this paper analyzes the hydrocarbon accumulation characteristics in two typical blocks of the Boxing and Wangjiagang oilfields, especially reservoir bed heterogeneity and migration conditions that influence oil and gas distribution, calculates the index of reservoir bed quality(IRQ) with a mathematical method, and discusses the relationship between driving force and resistance of hydrocarbon accumulation. Taking into account the characteristics of thin interbeds in beach-bar sandstones, an experimental model simulated the characteristics of hydrocarbon migration and accumulation in thin interbedded sandstones with reservoir bed heterogeneity. The results showed that hydrocarbon distribution and properties were extremely non-uniform. Reservoir bed and migration conditions controlled hydrocarbon accumulation in beach-bar sandstones. IRQ is above 0.4 in the main hydrocarbon region. Sand body distribution, structural configuration and fault systems controlled the direction of regional migration and location of hydrocarbon accumulation. Simulation experiments indicated that the change of driving force for hydrocarbon migration affected selective accumulation mechanisms. Hydrocarbon moved vertically along fault zones to the reservoir and resulted in the distribution of hydrocarbon in the reservoir. Two kinds of hydrocarbon accumulation models exist in the study area. One is a hydrocarbon accumulation model controlled by reservoir bed heterogeneity and the second is a hydrocarbon accumulation model controlled by a complex migration system with faults connecting sandbodies. Finally, different exploration strategies should be adopted for the detailed exploration for beach-bar sandstone reservoirs according to different geological backgrounds. | Guo Song Tan Lijuan Lin Chengyan Li Hongnan Lü Xiuxiang Wang Hongtao | 2014 | Petroleum Science2014，11，2： | 4 |
| 2 | 3-D consistency dynamic constitutive model of concrete显示文摘Based on the consistency-viscoplastic constitutive model,the static William-Warnke model with three-parameters is modified and a consistency-viscoplastic William-Warnke model with three-parameters is developed that considers the effect of strain rates. Then,the tangent modulus of the consistency viscoplastic model is introduced and an implicit backward Elure iterative algorithm is developed. Comparisons between the numerical simulations and experimental data show that the consistency model properly provides the uniaxial and biaxial dynamic behaviors of concrete. To study the effect of strain rates on the dynamic response of concrete structures,the proposed model is used in the analysis of the dynamic response of a simply-supported beam and the results show that the strain rate has a significant effect on the displacement and stress magnitudes and distributions. Finally,the seismic responses of a 278 m high arch dam are obtained and compared by using the linear elastic model,as well as rate-independent and rate-dependent William-Warnke three-parameter models. The results indicate that the strain rate affects the first principal stresses,and the maximal equivalent viscoplastic strain rate of the arch dam. Numerical calculations and analyses reveal that considering the strain rate is important in the safety assessments of arch dams located in seismically active areas. | Xiao Shiyun,Li Hongnan and Lin Gao School of Hydraulic Engineering,Dalian University of Technology,Dalian 116024,China | 2010 | Earthquake Engineering and Engineering Vibration2010，9，2： | 4 |
| 3 | Predicting the Useof Pirated Software:A Contingency Model IntegratingPerceived Risk with the Theory of Planned Behavior显示文摘 | Liao Chechen Lin Hongnan Liu Yuping | 2010 | Journal of Business Ethics2010，91，2： | 1 |
| 4 | Therapeutic effect of ketogenic diet treatment on type 2 diabetes显示文摘Diet plays an important role in diabetes development.The effect of ketogenic diet on type 2 diabetes remains elusive.In this study,we collect diabetes related physiological parameters and abdominal MRI images to evaluate the effect of ketogenic diet after 3-months of consecutive treatment.Ketogenic diet mitigates the diabetes symptom inferring from the statistically significant reduction of key diabetic physiological parameters such as Hemoglobin A1c(HbA1c)concentration,Triglyceride(TG),Fasting blood glucose(FBG),Body Mass Index(BMI),and adipose tissue volume.Moreover,we propose a new parameter to quantify the treating effect of ketogenic diet since Slope and Offset of Oral Glucose Tolerance Test(SOOGTT)incorporate more sampling points by fitting OGTT(Oral Glucose Tolerance Test)curve.SOOGTT shows statistically significant(P<0.001)treating effect of ketogenic diet on type 2 diabetes.We use artificial intelligence to segment adipose tissue for treatment evaluation,which shows that ketogenic diet reduces the amount of adipose tissue. | Fang Li Yang Shen Qun Chen Xingyu Li Hongnan Yang Canyang Zhang Jinjun Lin Zhicheng Du Chenyao Jiang Chengming Yang Dongmei Yu Peiwu Qin | 2022 | Journal of Future Foods2022，2，2： | 0 |
| 5 | Recombinant human thrombopoietin prior to mobilization chemotherapy facilitates platelet recovery in autologous transplantation in patients with lymphoma:Results of a prospective randomized study显示文摘Background:Chemotherapy plus granulocyte colony-stimulating factor (GCSF) regimen is one of the available approaches to mobilize peripheral blood progenitor cells (PBPCs).It causes thrombocytopenia and delays leukapheresis.This study aimed to evaluate the role of recombinant human thrombopoietin (rhTPO) before mobilization chemotherapy in facilitating leukapheresis in patients with lymphoma.Methods:In this randomized open-label phase 2 trial, patients were randomly assigned in a 1:2 ratio to receive mobilization with rhTPO plus GCSF in combination with chemotherapy (the rhTPO plus GCSF arm) or GCSF alone in combination with chemotherapy (the GCSF alone arm).The recovery of neutrophils and platelets and the amount of platelet transfusion were monitored.Results:Thirty patients were enrolled in this study between March 2016 and August 2018. Patients in the rhTPO plus GCSF arm (n = 10) had similar platelet nadir after mobilization chemotherapy (P=0.878) and similar amount of platelet transfusion (median 0 vs.1 unit,P=0.735) when compared with the GCSF alone arm (n = 20). On the day of leukapheresis, the median platelet count was 86 ×10^(9)/L (range 18-219) among patients who received rhTPO and 73 ×10^(9)/L (range 42-197) among those who received GCSF alone (P=0.982). After the use of rhTPO, the incidence of platelet count <75 ×10^(9)/L on the day of leukapheresis did not decrease significantly (30.0% vs. 50.0%,P=0.297).Platelet recovery after PBPC transfusion was more rapid in the rhTPO plus GCSF arm (median 8.0 days [95% confidence interval 2.9-13.1] to platelets ≥50 ×10^(9)/L vs. 11.0 days [95% confidence interval 8.6-13.4],P=0.011).The estimated total cost of the mobilization and reconstitution phases per patient was similar between the two treatmtent groups (P=0.362 andP=0.067,respectively).Conclusions:Our findings indicate that there was no significant clinical benefit of rhTPO use in facilitating mobilization of progenitor cells,but it may promote platelet recovery in the reconstitution phase after high-dose therapy.Trial registration:This trial has been registered in Clinicaltrials.gov as NCT03014102. | Hongnan Mo Peng Liu Yan Qin Xiaohui He Xiaohong Han Jiarui Yao Weicai Su Shuxiang Zhang Le Tang Fengyi Zhao Lin Gui Sheng Yang Jianliang Yang Shengyu Zhou Zhishang Zhang Yuankai Shi | 2021 | Chronic Diseases and Translational Medicine2021，7，3： | 0 |
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