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| 1 | Improvedendoscopicretrogradecholangiopancreatographybrushincreases diagnosticyieldofmalignantbiliarystrictures显示文摘AIM: To determine if a new brush design could im-prove the diagnostic yield of biliary stricture brushings. METHODS: Retrospective chart review was performed of all endoscopic retrograde cholangiopancreatography procedures with malignant biliary stricture brushing between January 2008 and October 2012. A standard wire-guided cytology brush was used prior to proto-col implementation in July 2011, after which, a new 9 French wire-guided cytology brush(Infinity sampling device, US Endoscopy, Mentor, OH) was used for all cases. All specimens were reviewed by blinded pa-thologists who determined whether the sample waspositive or negative for malignancy. Cellular yield was quantified by describing the number of cell clusters seen. RESULTS: Thirty-two new brush cases were compared to 46 historical controls. Twenty-five of 32 (78%) cases in the new brush group showed abnormal cellular find-ings consistent with malignancy as compared to 17 of 46(37%) in the historical control group(P = 0.0003). There was also a significant increase in the average number of cell clusters of all sizes(21.1 vs 9.9 clusters, P = 0.0007) in the new brush group compared to his-torical controls. CONCLUSION: The use of a new brush design for brush cytology of biliary strictures shows increased di-agnostic accuracy, likely due to improved cellular yield, as evidenced by an increase in number of cellular clus-ters obtained. | Shieh FK Luong-Player A Khara HS Liu H Lin F Shellenberger MJ Johal AS Diehl DL | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，7： | 4 |
| 2 | A calcineurin homologous protein inhibits GTPasestimulated Na-H exchange 显示文摘 | Lin X Barber DL | 1996 | Pro Natl Acad Sci USA1996，93，12： | 2 |
| 3 | Partial stapled hemorrhoidopexy versus eireular stapled hemorrhoidopexy for grade HI-IV prolapsing hemorrhoids : a two- year prospeetive controlled study 显示文摘 | Lin HC Ren DL He QL | 2012 | Teeh Col- oproetol2012，16，： | 1 |
| 4 | Stage 2 specific and differential expression of gap junctions in the mouse ovary: connexin specific roles in follicular regulation 显示文摘 | Wright CS Becker DL Lin JS | 2001 | Reproduction2001，121，1： | 1 |
| 5 | Chemokine receptor expression profiles in nasopharyngeal carcinoma and their association with metastasis and radiotherapy显示文摘 | Ou DL Chen CL Lin SB | 2006 | J Pathol2006，210，3： | 1 |
| 6 | Mechanical Properties and Microstructure of AZ31 Mg Alloy Processed by Two-step Equal Channel Angular Extrusion显示文摘 | Jin L Lin D L Mao DL | 2005 | Material Letter2005，59，： | 1 |
| 7 | Prone position ventilation induces sustained improvement in oxygenation in patients with acute respiratory distress syndrome who have a large shunt显示文摘 | Lee DL Chiang HT Lin SL | 2002 | Crit Care Med2002，30，7： | 1 |
| 8 | The distinct mechanisms of the antitumor activity of emodin in different types of cancer显示文摘 | Wei WT Lin SZ Liu DL | 2013 | On- col Rep2013，30，6： | 1 |
| 9 | Controlling potassium channel activities: Interplay between the membrane and intracellular factors 显示文摘 | Yi BA Minor DL Jr Lin YF | 2001 | Proc Natl Acad Sci USA2001，98，11： | 1 |
| 10 | Regulation of insulin-like growth factor-I messenger ribonucleic acid expression in Leydig cells显示文摘 | Lin T Wang DL Calkins JH | 1990 | Molecular and Cellular Endocrinology1990，73，： | 1 |
| 11 | Supercritical carbon dioxide ex- tract of Physalis peruviana induced cell cycle arrest and apopto- sis in human lung cancer H661 cells显示文摘 | Wu S J Chang SP Lin DL | 2009 | Food Chem Toxicol2009，47，6： | 1 |
| 12 | Isotopic analogs as internal standards for quantitative analyses by GC/MS-evaluation of cross-contribution to ions designated for the analyte and the isotopic internal standard 显示文摘 | Chang WT Lin DL Liu RH | 2001 | Forensic Sci Int2001，121，3： | 1 |
| 13 | Klebsiella pneumoniae liver abscess associated with septic endophthalmitis 显示文摘 | Liu YC Cheng DL Lin CL | 1986 | Arch Intern Med1986，146，10： | 1 |
| 14 | Interleukin-6 induces androgen responsiveness in prostate cancer cells through upregulation of androgen receptor expression 显示文摘 | Lin DL Whitney MC Yao Z | 2001 | Clin Cancer Res2001，7，： | 1 |
| 15 | Ethanol and acetaldehyde metabolism in chinese with different aldehyde dehydrogenase- 2 genotypes显示文摘 | Luu SU Wang MF Lin DL | 1995 | Proc Natl Sci Count Repub China B1995，19，3： | 1 |
| 16 | Matrix effects in the liquid chromatography-tandem mass spectrometry method of analysis显示文摘 | Liu HC Lin DL McCurdy HH | 2013 | Forensic Science Review2013，25，12： | 1 |
| 17 | ZEB1promotes epithelial-mesenchymal transition in cervical cancer metastasis显示文摘 | Ran J Lin DL Wu RF | 2015 | Fertil Steril2015，103，6： | 1 |
| 18 | Regulation of embryo implantation by nitric oxide in mouse显示文摘Intrauterine injection and zymography were used to investigate the effect of nitric oxide (NO) on embryo implantation in mice. On day 3, one uterine horn of female pregnant mice was injected intraluminally with various doses of nitric oxide synthase (NOS) inhibitor, N-nitro-L-arginine methyl ester (L-NAME), while the contralateral horn served as control. Animals were sacrificed by cervical dislocation on day 7 of gestation, and the number of implanted embryos in each horn was calculated. The results showed that lower doses (0.05mg L-NAME) did not inhibit implantation significantly (P > 0.05), but high doses (0.2 mg L- NAME) resulted in a significant reduction in the number of implanted embryos (P < 0.05). Co-administration of SNP, a generator of NO, with L-NAME would reverse the anti-implantation effect of L-NAME. To further understand the precise mechanism of NO in implantation, matrix metallo-proteinase (MMPs) activities were detected by gelatin zymography. The reduction in the number of implanted | Zhang, X Wang, HM Lin, HY Li, QL Liu, DL Qian, D Liu, GY Zhu, C | 2002 | Chinese Science Bulletin2002，47，17： | 1 |
| 19 | Apoptosis of terminally differentiated chondrocytes in culture显示文摘 | Gibson G Lin DL Roque M | 1997 | Exp Cell Res1997，223，6： | 1 |
| 20 | A novel anti-CD146 monoclonal antibody,AA98,inhibits angiogenesis and tumor growth显示文摘 | Yan XY Lin Y Yang DL | 2003 | Blood2003，102，： | 1 |
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