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| 1 | Encapsulating peritoneal sclerosis显示文摘Encapsulating peritoneal sclerosis(EPS) is a debilitating condition characterized by a fibrocollagenous membrane encasing the small intestine, resulting in recurrent small bowel obstructions. EPS is most commonly associated with long-term peritoneal dialysis, though medications, peritoneal infection, and systemic inflammatory disorders have been implicated. Many cases remain idiopathic. Diagnosis is often delayed given the rarity of the disorder combined with non-specific symptoms and laboratory findings. Although cross-sectional imaging with computed tomography of the abdomen can be suggestive of the disorder, many patients undergo exploratory laparotomy for diagnosis. Mortality approaches 50% one year after diagnosis. Treatment for EPS involves treating the underlying condition or eliminating possible inciting agents(i.e. peritoneal dialysis, medications, infections) and nutritional support, frequently with total parenteral nutrition. EPSspecific treatment depends on the disease stage. In the inflammatory stage, corticosteroids are the treatment of choice, while in the fibrotic stage, tamoxifen may be beneficial. In practice, distinguishing between stages may be difficult and both may be used. Surgical intervention, consisting of peritonectomy and enterolysis, is timeconsuming and high-risk and is reserved for situations in which conservative medical therapy fails in institutions with surgical expertise in this area. Herein we review the available literature of the etiology, pathogenesis, diagnosis, and treatment of this rare, but potentially devastating disease. | Christopher J Danford Steven C Lin Martin P Smith Jacqueline L Wolf | 2018 | World Journal of Gastroenterology2018，24，28： | 13 |
| 2 | 曹雪涛院士科研团队论文荣膺中国百篇最具影响国际学术论文--长链非编码RNA1nc-DC通过STAT3调控人DC的分化和功能显示文摘树突状细胞(DC)是免疫系统中重要的抗原提呈细胞,其成熟和功能状态决定着免疫应答的走向和强度。哺乳动物基因组能够转录产生大量的长链非编码RNA(long noncoding RNA,IncRNA),其在免疫系统中的功能还知之甚少。
曹雪涛院十科研团队王品副教授课题组采用了转录组芯片二代测序高通量筛选方法、RNA-pulldown、ChIP-seq等技术展开了对IncRNA在DC分化和功能中作用的研究,发现并鉴定了特异性高表达于DC的1ncRNA,命名为1nc-DC,其可通过抑制STAT3去磷酸化,从而促进DC分化和功能。该研究成果发表于Science杂志[2014,344(6181):310-313],并于2015年12月被评为“中国百篇最具影响国际学术论文”。 | wang p xue y han y lin l wu c xu s jiang z xu j liu q cao x | 2016 | 中国肿瘤生物治疗杂志2016，23，1： | 10 |
| 3 | 欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。 | 刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F | 2018 | 中华高血压杂志2018，26，4： | 3 |
| 4 | Ultrasonic tissue characterization evaluates myocardial viability and ischemia in patients with coronary artery disease显示文摘 | LIN L C YEN R F HWANG J J | 2000 | Ultrasound Med Biol2000，26，5： | 2 |
| 5 | Assessment of menopause-induced myocardial changes by integrated backscatter during inotropic stimulation and atropine injection显示文摘 | HO Y L LIN L C YEN M L | 2002 | Ultrasound Med Biol2002，28，7： | 2 |
| 6 | Ultrasonic tissue characterization with integrated backscatter during inotropic stimulation显示文摘 | WU C C LIU Y B LIN L C | 2000 | Ultrasound Med Biol2000，26，9： | 2 |
| 7 | A new LDA-based face recognition system which can solve the small sample size problem 显示文摘 | Chen L F Liao H Y M Lin J C | 2000 | Pattern Recognition2000，33，10： | 1 |
| 8 | Modeling and High -precision Control of a Ball-screw-drive Stage 显示文摘 | Chen C L Jang M J Lin K C | 2004 | Precision Engineering2004，28，： | 1 |
| 9 | Acetyl danshenxinkun a from Salvia miltiorrhiza 显示文摘 | Lin Y L Liu C Y Chen T H etal | 2003 | J Chin Med2003，14，： | 1 |
| 10 | Rainbow trout has two genes for growth hormone显示文摘 | Agellon L B Davies S L Lin C M | 1988 | Mol Rep Develop1988，1，： | 1 |
| 11 | Strategic shotgun proteomics approach for efficient construction of an expression map of targeted protein families in hepatoma cell lines显示文摘 | Lee C L Hsiao H H Lin C W | 2003 | Proteomics2003，3，12： | 1 |
| 12 | Vital staining of cardiac myocytes during embryonic stem cell cardiogenesis in vitro显示文摘 | LIN W I SAMUELSON L C | 1996 | Circ Res1996，78，4： | 1 |
| 13 | A mesh reconstruction algorithm driven by an intrinsic property of a point cloud显示文摘 | Lin H W Tai C L Wang G J | 2004 | Computer-Aided Design2004，36，1： | 1 |
| 14 | Low-density parity-check coded recording systems with run-length-limited constraints显示文摘 | Chen H Y Lin M C Ueng Y L | 2008 | IEEE Transactions on Magnetics2008，44，9： | 1 |
| 15 | Time-dependent effects of intermittent hydrostatic pressure on aeticular chondrocyte type II collagen and aggrecan mRNA expression显示文摘 | SMITH R L LIN J TRINDADE M C | 2000 | J Reha bil Res Dev2000，37，2： | 1 |
| 16 | MR Imaging of non-alcoholic Wernicke encephalopathy:a follow-up study显示文摘 | 2hong C lin L Fei G | 2005 | AJNR Am J Neuroradiol2005，26，9： | 1 |
| 17 | Liquefaction of CCA-treated wood and elimination of metals from the solvent by precipitation显示文摘 | LIN L Z HSE C Y | 2005 | Holzforschung2005，59，3： | 1 |
| 18 | On the Marcinkiewicz integral with variable kernels显示文摘 | DING Y LIN C C SHAO S L | 2004 | Indiana Univ Math J2004，53，： | 1 |
| 19 | A new experimental approach to evaluate friction in ring test显示文摘 | WANG J P LIN F L HUANG B C | 2008 | Journal of Materials Processing Technology2008，197，13： | 1 |
| 20 | Impetus for Action: A Culture Analysis Justice and Organizational Citizenship Behavior in Chinese Society 显示文摘 | FARH J L EARLE C LIN S C | 1997 | Administrative Science Quarterly1997，42，3： | 1 |
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