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80篇 您的检索式:作者名="Lima MA"
    题名 作者 年代 出处 被引量
1Innate and adaptive immune responses toward nanomedicines显示文摘Since the commercialization of the frst liposomes used for drug delivery,Doxil/Caelyx® and Myocet®,tremendous progress has been made in understanding interactions between nanomedicines and biological systems.Fundamental work at the interface of engineering and medicine has allowed nanomedicines to deliver therapeutic small molecules and nucleic acids more effciently.While nanomedicines are used in oncology for immunotherapy or to deliver combinations of cytotoxics,the clinical successes of gene silencing approaches like patisiran lipid complexes(Onpattro®)have paved the way for a variety of therapies beyond cancer.In parallel,the global severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic has highlighted the potential of mR NA vaccines to develop immunization strategies at unprecedented speed.To rationally design therapeutic and vaccines,chemists,materials scientists,and drug delivery experts need to better understand how nanotechnologies interact with the immune system.This review presents a comprehensive overview of the innate and adaptative immune systems and emphasizes the intricate mechanisms through which nanomedicines interact with these biological functions.Iara Maíra de Oliveira Viana Sabrina Roussel Joan Defrêne Eliana Martins Lima Frédéric Barabé Nicolas Bertrand 2021Acta Pharmaceutica Sinica B2021,11,4:5
2Brainstem gliomas--retrospective analysis of 86 patients显示文摘Ueoka DI Nogueira J Campos JC Maranhao Filho P Ferman S Lima MA 2009中国神经肿瘤杂志2009,7,3:3
3Interstitial cells of Cajal in chagasic megaesophagus 显示文摘de Lima MA Cabrine - Santos M Tavares MG 2008Ann Diagn Pathol2008,12,4:1
4MTRR 66A>G polymorphism as maternal risk factor for Down syndrome:a meta-analysis显示文摘Amorim MR Lima MA 2013Genet Test Mol Biomarkers2013,17,1:1
5Medical education content required for kernicterus risk recognition显示文摘de Lima GM Porto MA da Cunha AL 2012Iran J Pediatr2012,22,2:1
6Climate and small ro- dent dynamics in semi-arid Chile : the role of lateral and vertical perturbations and intra-specific processes 显示文摘Lima M Previtali MA Meserve PL 2006Climate Research2006,30,2:1
7Neonatal cardiac rhabdo- myoma: Case report and clinical epidemiologic consideration 显示文摘Lima RV Tortes MA Hernandez SF 1998Arch Inst Cardiol Mex1998,7,68:1
8P2X 7receptor activity regulation:the role of CD44proteoglycan GAG chains显示文摘Moura GE Lucena SV Lima MA 2015Cell Death Dis2015,266,:1
9Traumatic subdural hygromas: proposed pathogenesis based classification 显示文摘Zanini MA de Lima Resende LA de Souza Faleiros AT 2008J Trauma2008,64,3:1
10Dynamic mutation and human disorders: the spinocerebellar ataxias显示文摘Costa Lima MA Pimentel MM 2004Int J Mol Med2004,13,2:1
11Expression of the Fas-ligand gene in ejaculated sperm from adolescents with and without varicocele 显示文摘DEL GIUDICE PT LIMA SB CENEDEZE MA 2010Assist Reprod Genet2010,27,23:1
12Thyroid peroxidase and thyroglobulin expression in normal human thyroid glands显示文摘Lima MA Gontijo VA Schmitt FCL 1998Endocr Pathol1998,9,:1
13Less Delta mt DNA4977 than normal in various types of tumors suggests that cancer cells are essentially free of thismutation显示文摘Dani MA Dani SU Lima SP 2004Genet Mol Res2004,3,3:1
14Seizures and their outcome in progressive multifocal leukoencephalopathy显示文摘Lima MA Drislane FW Koralnik IJ 2006Neurology2006,66,2:1
15Relationship between α5β1 and expression of cellular proteins c-Myc,Bcl-2 and Bax in gastric carcinomas显示文摘Lima MA Ferreira MV Barros MA 0,,02:1
16Human papillomavirus genotype attribution in invasive cervical cancer:a retrospective cross-sectional worldwide study显示文摘de Sanjose S Quint WG Alemany L Geraets DT Klaustermeier JE Lloveras B Tous S Felix A Bravo LE Shin HR Vallejos CS de Ruiz PA Lima MA Guimera N Clavero O Alejo M Llombart-Bosch A Cheng-Yang C Tatti SA Kasamatsu E Iljazovic E Odida M Prado R Seoud M Grce M Usubutun A Jain A Suarez GA Lombardi LE Banjo A Menéndez C Domingo EJ Velasco J Nessa A Chichareon SC Qiao YL Lerma E Garland SM Sasagawa T Ferrera A Hammouda D Mariani L Pelayo A Steiner I Oliva E Meijer CJ AlJassar WF Cruz E Wright TC Puras A Llave CL Tzardi M Agorastos T Garcia-Barriola V Clavel C Ordi J Andújar M Castellsagué X Sánchez GI Nowakowsld AM Bornstein J Mu(n)oz N Bosch FX Retrospective International Survey and HPV Time Trends Study Group 2010Lancet Oncol2010,11,11:1
17Factors associated withrecurrence of cervical intraepithelial neoplasia after conization inHIV -infected and noninfected women 显示文摘Lodi CT Michelin MA Lima MI 2011Arch Gynecol Obstet2011,284,1:1
18Expression of the Fas-ligand gene in ejaculated sperm Irom adolescents with and without varicocele显示文摘Del Giudice PT Lima SB Cenedeze MA 2010J Assist Reprod Genet2010,27,23:1
19Atherosclerotic plaque characteriza- tion by muhidetector row computed tomography angiography 显示文摘Cordeiro MA Lima JA 2006J Am Coll Cardiol2006,,8:1
20Mechanisms of secondary degenation in the central nervous system during acute neural disorders and white matter damage fJ1 显示文摘Guimaraes JS Freire MA Lima RR 2009Rev Neurol2009,48,6:1
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