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| 1 | Flexibility in the order of action and in the enzymology of the nuclease, polymerases, and ligase of vertebrate non-homologous DNA end joining: relevance to cancer, aging, and the immune system显示文摘加入的 Nonhomologous 脱氧核糖核酸结束(NHEJ ) 是为在人的房间并且在多细胞的优核质的双海滨脱氧核糖核酸裂缝的修理的主要小径。双海滨裂缝的原因经常碎裂在损坏的地点的脱氧核糖核酸,导致在那里的信息的损失。NHEJ 不恢复失去的信息并且可以将切除另外的核苷酸在修理过程期间。修理大量 overhang 并且损坏配置的能力反映 NHEJ 的核酸酶,聚合酶,和连接酶的灵活性。单个部件的灵活性也解释 NHEJ 能在修理脱氧核糖核酸结束的任何给定的对的方法的大数字。局部地,在 NHEJ 的地点,修理可以贡献癌症和老化的信息的损失,而是由 NHEJ 的行动保证染色体的全部片断没被失去。 | Michael R Lieber Haihui Lu Jiafeng Gu Klaus Schwarz | 2008 | Cell Research2008，18，1： | 5 |
| 2 | Perioperative glucose management and outcomes in liver transplant recipients: A qualitative systematic review显示文摘AIM To investigate the relationship between post-liver transplantation(LT) glycemic control and LT outcomes. METHODS A qualitative systematic review on relevant prospective interventions designed to control glucose levels including insulin protocols. Studies investigating an association between glycemic control and post-LT outcomes such as mortality, graft rejection, and infection rate were reviewed. Pub Med, EMBASE, and other databases were searched through October 2016. RESULTS Three thousands, six hundreds and ninety-two patients from 14 studies were included. Higher mortality rate was seen when blood glucose(BG) ≥ 150 mg/dL(P = 0.05). BG ≥ 150 mg/dL also led to higher rates of infection. Higher rates of graft rejection were seen at BG > 200 mg/dL(P < 0.001). Mean BG ≥ 200 mg/dL was associated with more infections(P = 0.002).Nurse-initiated protocols and early screening strategies have shown a reduction in negative post-LT outcomes.CONCLUSION Hyperglycemia in the perioperative period is associated with poor post-LT outcomes. Only a few prospective studies have designed interventions aimed at managing post-LT hyperglycemia, post-transplant diabetes mellitus(PTDM) and their impact on post-LT outcomes. | Prani Paka Sarah R Lieber Ruth-Ann Lee Chirag S Desai Robert E Dupuis Alfred Sidney Barritt | 2018 | World Journal of Transplantation2018，8，3： | 2 |
| 3 | ATT Filament Winding Technology显示文摘 | D Noss R Lieber | 2002 | Chemical Fibers International2002，52，6： | 1 |
| 4 | Single-Nanowire Electrically Driven Lasers显示文摘 | X Duan Y Huang R Agarwal CM Lieber | 2003 | Nature2003，421，： | 1 |
| 5 | Architecture of selected muscles of the arm and forearm:anatomy and implications for tendon transfer 显示文摘 | Lieber R L Jacobson M D Fazeli BM | 1992 | J HandSurg (Am)1992，17，5： | 1 |
| 6 | Hypoxia-inducible factor-1 ( HIF-113 )is upregulated in a HIF-1 t-dependent manner in 518A2 human melanoma cells under hypoxic conditions显示文摘 | Mandl M KapeUer B Lieber R | 2013 | Biochem Biophys Res Commun2013，434，1： | 1 |
| 7 | The mechanism of double-strand DNA break repair by the non-homologous DNA end-joining pathway显示文摘 | Lieber M R | 2010 | Annu Rev Biochem2010，79，1： | 1 |
| 8 | Mechanism a-and regulation of human nonhomologous DNA end joining 显示文摘 | LIEBER M R MA Y PANNICKE U | 2003 | Nature Rev Mol Cell Biol2003，4，： | 1 |
| 9 | Reproduction of mucosal disease with cytopathogenic bovine viral diarrhea virus selected in vitro 显示文摘 | Moenning V Frey H R Lieber E | 1990 | Vet Rec1990，，127： | 1 |
| 10 | Density and hydration of fresh and fixed skeletal muscle显示文摘 | Ward S R Lieber R L | 2005 | J Biomech2005，38，11： | 1 |
| 11 | Reservoir quality modeling of tight-gas sands in Wamsutter field:Integration of diagenesis, petroleum systems, and production data显示文摘 | Tobin R C McClain T Lieber R B | 2010 | AAPG Bulletin2010，94，8： | 1 |
| 12 | Global and local architecture of the mammalian microRNA-transcription factor regulatory network显示文摘 | Shalgi R Lieber D Oren M | 2007 | PLoS Comput Biol2007，3，7： | 1 |
| 13 | Single-nanowire electrically driven lasers 显示文摘 | DUAN Xiang-feng HUANG Yu AGARWAL R LIEBER C M | 2003 | Nature2003，421，： | 1 |
| 14 | In vivo measurement of human wrist extensor muscle sarcomere length changes显示文摘 | Lieber R L Loren G J | 1994 | J Neurophysiol1994，71，3： | 1 |
| 15 | Skeletal myosinⅡstructure and function 显示文摘 | Lutz G J Lieber R L | 1999 | Exerc Sport Sci Rev1999，27，： | 1 |
| 16 | Lasing in single cadmium sulfide nanowire optical cavities 显示文摘 | AGARWAL R BARRELET C J LIEBER C M | 2005 | Nano Lett2005，5，5： | 1 |
| 17 | Mechanism and regulation of human non-homologous DNA end-joining 显示文摘 | LIEBER M R MA Y PANNICKE U | 2003 | Nat Rev Mol Cell Biol2003，4，9： | 1 |
| 18 | Veterans affairs cooperative study polyenylphosph-atidylcholine in alcoholic liver disease显示文摘 | Lieber CS Weiss DG Groszmann R | 2013 | Clin Exp Res2013，27，1： | 1 |
| 19 | The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway显示文摘 | LIEBER M R | 2010 | Annual Review of Biochemistry2010，79，1： | 1 |
| 20 | A review of clinical and pathological prostatitis syndromes显示文摘 | Roberts R O Lieber M M Bostwick D G | 1997 | Urology1997，49，： | 1 |
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