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| 1 | Hybrid brightfield and darkfield transport of intensity approach for high-throughput quantitative phase microscopy显示文摘Transport of intensity equation(TIE)is a well-established non-interferometric phase retrieval approach that enables quantitative phase imaging(QPI)by simply measuring intensity images at multiple axially displaced planes.The advantage of a TIE-based QPI system is its compatibility with partially coherent illumination,which provides speckle-free imaging with resolution beyond the coherent diffraction limit.However,TIE is generally implemented with a brightfield(BF)configuration,and the maximum achievable imaging resolution is still limited to the incoherent diffraction limit(twice the coherent diffraction limit).It is desirable that TIE-related approaches can surpass this limit and achieve high-throughput[high-resolution and wide field of view(FOV)]QPI.We propose a hybrid BF and darkfield transport of intensity(HBDTI)approach for highthroughput quantitative phase microscopy.Two through-focus intensity stacks corresponding to BF and darkfield illuminations are acquired through a low-numerical-aperture(NA)objective lens.The high-resolution and large-FOV complex amplitude(both quantitative absorption and phase distributions)can then be synthesized based on an iterative phase retrieval algorithm taking the coherence model decomposition into account.The effectiveness of the proposed method is experimentally verified by the retrieval of the USAF resolution target and different types of biological cells.The experimental results demonstrate that the half-width imaging resolution can be improved from 1230 nm to 488 nm with 2.5×expansion across a 4×FOV of 7.19 mm2,corresponding to a 6.25×increase in space-bandwidth product from∼5 to∼30.2 megapixels.In contrast to conventional TIE-based QPI methods where only BF illumination is used,the synthetic aperture process of HBDTI further incorporates darkfield illuminations to expand the accessible object frequency,thereby significantly extending the maximum available resolution from 2NA to∼5NA with a∼5×promotion of the coherent diffraction limit.Given its capability for high-throughput QPI,the proposed HBDTI approach is expected to be adopted in biomedical fields,such as personalized genomics and cancer diagnostics. | Linpeng Lu Jiaji Li Yefeng Shu Jiasong Sun Jie Zhou Edmund Y.Lam Qian Chen Chao Zuo | 2022 | Advanced Photonics2022，4，5： | 2 |
| 2 | Effects of AlCoCrFeNiTi high-entropy alloy on microstructure and mechanical properties of pure aluminum显示文摘A new kind of AlCoCrFeNiTi high-entropy alloy(HEA)as a grain refiner was prepared by vacuum arc melting.In this work,the effects of HEA(1.0 wt.%,2.0 wt.%and 3.0 wt.%)on the microstructure and mechanical properties of pure aluminum were studied.The microstructure was characterized and examined by scanning electron microscope(SEM),energy dispersive X-ray spectroscopy(EDS),X-ray diffraction(XRD),electron probe micro-analyzer(EPMA)and transmission electron microscopy(TEM)to indicate the refining abilities and mechanism of HEA on pure aluminum.Results show that the addition of HEA refined both the macrostructure and microstructure of pure aluminum.When 1.0 wt.%HEA was added,most coarse columnar grains were refined into equiaxed crystals,and as the amount of HEA increased to 2.0 wt.%and3.0 wt.%,aluminum grains were further refined,and the grain boundaries were nearly indistinguishable.Moreover,the morphology ofα-Al transformed from coarse columnar crystals to equiaxed grains,and the mean size ofα-Al grains decreased from 374μm to 27μm.The Al3Ti,Al3Ni,and nano-phase precipitated from the aluminum alloy with HEA in the solidification.The typical rod-like nano-phases distributed interdendritic regions ofα-Al.The average length of nano-phases is 2568 nm,4372 nm,and 6907 nm and the average diameter is 112 nm,103 nm,and 92 nm when 1.0 wt.%,2.0 wt.%and 3.0 wt.%HEA were added to the pure aluminum,respectively.The ultimate tensile strength(UTS)and yield strength(YS)were improved in all samples,whereas the elongation(El)was decreased with increasing HEA concentration.When 3.0 wt.%HEA was added into the aluminum melt,the UTS was improved by 145.2%from62 MPa to 152 MPa,the YS was increased by 173.8%from 42 MPa to 115 MPa,and the El was decreased by 33.3%from 39%to 26%. | Qinglin Li Shang Zhao Xuepeng Bao Yushi Zhang Yuqian Zhu Chuangzao Wang Yefeng Lan Yuxin Zhang Tiandong Xia | 2020 | Journal of Materials Science & Technology2020，52，17： | 2 |
| 3 | Impaired Autophagy in Hilar Mossy Cells of the Dentate Gyrus and Its Implication in Schizophrenia显示文摘Schizophrenia(SCZ) is a complex disease that has been regarded as a neurodevelopmental,synaptic or epigenetic disorder.Here we provide evidence that neurodegeneration is implicated in SCZ.The DTNBP1(dystrobrevin-binding protein 1) gene encodes dysbindin-1and is a leading susceptibility gene of SCZ.We previously reported that the dysbindin-1C isoform regulates the survival of the hilar glutamatergic mossy cells in the dentate gyrus,which controls the adult hippocampal neurogenesis.However,the underlying mechanism of hilar mossy cell loss in the dysbindin-1-deficient sandy(sdy) mice(a mouse model of SCZ) is unknown.In this study,we did not observe the apoptotic signals in the hilar mossy cells of the sdy mice by using the TUNEL assay and immunostaining of cleaved caspase-3or necdin,a dysbindin-1- and p53-interacting protein required for neuronal survival.However,we found that the steady-state level of LC3-Ⅱ,a marker of autophagosomes,was decreased in the hippocampal formation in the mice lacking dysbindin-1C.Furthermore,we observed a significant reduction of the cytosolic LC3-Ⅱ puncta in the mossy cells of sdy mice.In addition,overexpression of dysbindin-1C,but not 1A,in cultured cells increased LC3-Ⅱ level and the LC3 puncta in the transfected cells.These results suggest that dysbindin-1C deficiency causes impaired autophagy,which is likely implicated in the pathogenesis of SCZ. | Yefeng Yuan Hao Wang Zongbo Wei Wei Li | 2015 | Journal of Genetics and Genomics2015，42，1： | 2 |
| 4 | Review on Additive Manufacturing of Single-Crystal Nickel-based Superalloys显示文摘The conventional fabrication process for single-crystal nickel-based superalloy materials is directional solidifica-tion,which is classified as casting.With the rapid development of additive manufacturing(AM)technologies,a novel process for fabricating single-crystal superalloys has become possible.This article reviews recent research on the AM of single-crystal nickel-based superalloys.Laser AM technologies,particularly directed energy deposition,are mainly used to repair single-crystal materials.Electron beam powder bed fusion is an innovative method for the direct fabrication of single-crystal materials.Accordingly,the mechanisms of single-crystal formation during AM are analyzed to elucidate the potential of this process route.Furthermore,this article discusses the challenges faced by AM for single-crystal fabrication,and provides perspectives on the trends of future developments. | Yang Li Xiaoyu Liang Yefeng Yu Dongfang Wang Feng Lin | 2022 | Chinese Journal of Mechanical Engineering(Additive Manufacturing Frontiers)2022，1，1： | 2 |
| 5 | Gas lubrication analy- sis method of step-dimpled face mechanical seals 显示文摘 | Bai Shaoxian Peng Xudong Li Yefeng | 2012 | ASME J Tribo12012，134，01： | 1 |
| 6 | Effect of rare earth cerium addition on the microstructure and tensile properties of hypereutectic Al-20% Si alloy显示文摘 | Li Qinglin Xia Tiandong Lan Yefeng | | 0，，： | 1 |
| 7 | A Hydrodynamic laser surface-textured gas mechanical face seal 显示文摘 | Bai Shaoxian Peng Xudong Li Yefeng | 2010 | Tribology Letters2010，38，： | 1 |
| 8 | A Hydrodynamic Laser Surface-Textured Gas Mechanical Face Seal显示文摘 | Shaoxian Bai Xudong Peng Yefeng Li Songen Sheng | 2010 | Tribology Letters2010，，2： | 1 |
| 9 | Effect of in situ '/-A1203 particles on the microstructure of hypereutectic A1-20% Si alloy 显示文摘 | Li Qinglin Xia Tiandong Lan Yefeng | 2013 | Journal of Alloys and Compounds2013，557，： | 1 |
| 10 | A hydrodynamic laser surface textured gas mechanical face seal 显示文摘 | Bai Shaoxian Peng Xudong Li Yefeng | 2010 | Tribology Letters2010，38，2： | 1 |
| 11 | A hydrodynamic laser surface-textured gas mechanical face seal 显示文摘 | Bai Shaoxian Peng Xudong Li Yefeng | 2010 | Tribology Letters2010，38，2： | 1 |
| 12 | A parallel line detection algorithm based on HMM decoding显示文摘 | ZHENG YEFENG LI HUIPING DOERMANN D | 2005 | IEEE Transactions on Pattern Analysis and Machine Intelligence2005，27，5： | 1 |
| 13 | Research on internal damping algorithm of marine inertial navigation system显示文摘 | Li Kui Liu Fang Xu Yefeng | 2011 | Intelligent Computing and Information Science2011，135，： | 1 |
| 14 | A parallel-line detection algorithm based on HMM decoding显示文摘 | Yefeng Zheng Huiping Li David Doermann | 2005 | IEEE Trans on PAMI2005，27，5： | 1 |
| 15 | A hydrodynamic laser surface-textured gas mechanical face seal显示文摘 | Bai Shaoxian Peng Xudong Li Yefeng | 2010 | Tribol Letters2010，38，2： | 1 |
| 16 | A Hy- drodynamic Laser Surface Textured Gas Mechanical Face Seal显示文摘 | Bai Shaoxian Peng Xudong Li Yefeng | 2010 | Tribology Letters2010，38，2： | 1 |
| 17 | A hydrodynamic laser surface textured gas mechanical face seal 显示文摘 | Bai Shaoxian Peng Xudong Li Yefeng | 2010 | Tribology Letters2010，38，2： | 1 |
| 18 | A hydro- dynamic laser surface-textured gas mechanical face seal 显示文摘 | Bai Shaoxian Peng Xudong Li Yefeng | 2010 | Tribology Letters2010，38，2： | 1 |
| 19 | Synchronous Synthesis and Immobilization of Metal Phthalocyanine for Aerobic Oxidation of Styrene显示文摘In this study,the precursor 4-(4-carboxy-phenoxy)phthalonitrile(CPPN)was first bonded onto the silica gel surface modified with poly(glycidyl methacrylate)(PGMA)(PGMA/SiO2)to prepare CPPN-PGMA/SiO2,and metal phthalocyanine(MPc;M=Co,Fe,Cu,Mn)was supported on the PGMA/SiO2 surface to prepare MPc-PGMA/SiO2 by synchronous synthesis and immobilization with phthalonitrile and metal salt in the solution.The chemical composition and surface morphology were characterized by the Fourier transform infrared(FTIR)spectroscopy,UV-Vis spectroscopy,scanning electron microscopy(SEM),X-ray photoelectron spectroscopy(XPS),and thermogravimetry analysis(TGA).The catalytic performance of MPc-PGMA/SiO2 in epoxidation of styrene was also investigated with molecular oxygen acting as the oxidant.The results show that MPc-PGMA/SiO2 can efficiently and selectively catalyze molecular oxygen for oxidation of styrene to styrene oxide under mild conditions.However,the catalytic activity differs substantially depending on the central metal,and a highest catalytic activity is achieved by CoPc-PGMA/SiO2.The CoPc-PGMA/SiO2 amount and temperature can also affect the catalytic oxidation of styrene,and at normal atmospheric pressure,a maximum conversion rate of styrene(99%)and selectivity of styrene oxide(53%)are obtained using 0.1 g of CoPc-PGMA/SiO2(22.61μmol of CoPc)at 100℃ for 6 h.CoPc-PGMA/SiO2 also has excellent reusability,and the conversion rate of styrene is still over 90%after 5 cycles. | Liu Yefeng LüYing Li Zeyu Shen Yue Wang Ruixin | 2020 | China Petroleum Processing & Petrochemical Technology2020，22，4： | 1 |
| 20 | A parallelline detection algorithm based on HMM decoding显示文摘 | Zheng Yefeng Li Huiping Doermann D | 2005 | IEEE Trans on PAMI2005，27，5： | 1 |
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