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| 1 | Conceptualizing and Measuring Economic Resilience of Resource-based Cities: Case Study of Northeast China显示文摘This paper develops a conceptual model and an indicator system for measuring economic resilience of resource-based cities based on the theory of evolutionary resilience and the related concepts of persistence, adaptation, and transformation. Nineteen resource-based cities in Northeast China were analyzed using the indicator system. The results showed that Liaoning and Jilin provinces had higher economic resilience than Heilongjiang Province. Panjin, Benxi, and Anshan in Liaoning Province were the top three cities, while Shuangyashan and other coal-based cities in Heilongjiang Province ranked last. Metals-and petroleum-based cities had significantly higher resilience than coal-based cities. The differences in persistence, adaptability, transformation, and resilience among resource-based cities decreased since the introduction of the Northeast Revitalization Strategy in 2003. Forestry-based cities improved the most in terms of resilience, followed by metals-based and multiple-resource cities; however, resilience dropped for coal-based cities, and petroleum-based cities falling the most. The findings illustrate the importance and the way to develop a differentiated approach to improve resilience among resource-based cities. | TAN Juntao ZHANG Pingyu LO Kevin LI Jing LIU Shiwei | 2017 | Chinese Geographical Science2017，27，3： | 27 |
| 2 | Drug resistance and new therapies in colorectal cancer显示文摘Colorectal cancer(CRC) is often diagnosed at an advanced stage when tumor cell dissemination has taken place. Chemo-and targeted therapies provide only a limited increase of overall survival for these patients. The major reason for clinical outcome finds its origin in therapy resistance. Escape mechanisms to both chemo-and targeted therapy remain the main culprits. Here, we evaluate major resistant mechanisms and elaborate on potential new therapies. Amongst promising therapies is α-amanitin antibodydrug conjugate targeting hemizygous p53 loss. It becomes clear that a dynamic interaction with the tumor microenvironment exists and that this dictates therapeutic outcome. In addition, CRC displays a limited response to checkpoint inhibitors, as only a minority of patients with microsatellite instable high tumors is susceptible. In this review, we highlight new developments with clinical potentials to augment responses to checkpoint inhibitors. | Kevin Van der Jeught Han-Chen Xu Yu-Jing Li Xiong-Bin Lu Guang Ji | 2018 | World Journal of Gastroenterology2018，24，34： | 21 |
| 3 | Lane departure warning systems and lane line detection methods based on image processing and semantic segmentation:A review显示文摘Recently,the development and application of lane line departure warning systems have been in the market.For any of the systems,the key part of lane line tracking,lane line identification,or lane line departure warning is whether it can accurately and quickly detect lane lines.Since 1990 s,they have been studied and implemented for the situations defined by the good viewing conditions and the clear lane markings on road.After then,the accuracy for particular situations,the robustness for a wide range of scenarios,time efficiency and integration into higher-order tasks define visual lane line detection and tracking as a continuing research subject.At present,these kinds of lane marking line detection methods based on machine vision and image processing can be divided into two categories:the traditional image processing and semantic segmentation(includes deep learning)methods.The former mainly involves feature-based and model-based steps,and which can be classified into similarity-and discontinuity-based ones;and the model-based step includes different parametric straight line,curve or pattern models.The semantic segmentation includes different machine learning,neural network and deep learning methods,which is the new trend for the research and application of lane line departure warning systems.This paper describes and analyzes the lane line departure warning systems,image processing algorithms and semantic segmentation methods for lane line detection. | Weiwei Chen Weixing Wang Kevin Wang Zhaoying Li Huan Li Sheng Liu | 2020 | Journal of Traffic and Transportation Engineering(English Edition)2020，7，6： | 14 |
| 4 | Analyzing Industrial Structure Evolution of Old Industrial Cities Using Evolutionary Resilience Theory:A Case Study in Shenyang of China显示文摘The recession and revitalization of old industrial cities concerns urban industrial evolution and its characteristics. Based on the theory of evolutionary resilience, we developed an analytical framework for the industrial structure evolution of old industrial cities, and applied the framework to a case study in Shenyang. The following conclusions are drawn. First, since 1978, Shenyang's industrial growth capacity has shown fluctuation between ‘contraction-expansion'. As the secondary industry has a much stronger expansionary and contractionary capacity for growth, this results in lacking stability leading to industrial structure transformation. Second, since 1999, the orientation towards a high-end manufacturing industry in Shenyang has weakened, and the evolution of the new and old growth path is characterized by low-end orientation. Third, since 2007, Shenyang's industrial innovation output capacity has dropped sharply which has been significantly affected by scientific and technological personnel and enterprise-owed science and technology institutions and to a less extent by R&D expenditure. We applied the resilience theory to study the industrial evolution of an old industrial city, explored new study perspectives on industrial evolution and verified the applicability of the resilience theory. This paper provides a scientific reference for understanding the recent deceleration in economic growth in the Northeast old industrial base, and for exploring new paths toward revitalization. | GUAN Haoming LIU Wenxin ZHANG Pingyu LO Kevin LI Jing LI Liangang | 2018 | Chinese Geographical Science2018，28，3： | 12 |
| 5 | Calcium signaling and T-type calcium channels in cancer cell cycling显示文摘Regulation of intracellular calcium is an important signaling mechanism for cell proliferation in both normal and cancerous cells. In normal epithelial cells, free calcium concentration is essential for cells to enter and accomplish the S phase and the M phase of the cell cycle. In contrast, cancerous cells can pass these phases of the cell cycle with much lower cytoplasmic free calcium concentrations, indicating an alternative mechanism has developed for fulfilling the intracellular calcium requirement for an increased rate of DNA synthesis and mitosis of fast replicating cancerous cells. The detailed mechanism underlying the altered calcium loading pathway remains unclear; however, there is a growing body of evidence that suggests the T-type Ca2+ channel is abnormally expressed in cancerous cells and that blockade of these channels may reduce cell proliferation in addition to inducing apoptosis. Recent studies also show that the expression of T-type Ca2+ channels in breast cancer cells is proliferation state dependent, i.e. the channels are expressed at higher levels during the fast-replication period, and once the cells are in a non-proliferation state, expression of this channel isminimal. Therefore, selectively blocking calcium entry into cancerous cells may be a valuable approach for preventing tumor growth. Since T-type Ca2+ channels are not expressed in epithelial cells, selective T-type Ca2+ channel blockers may be useful in the treatment of certain types of cancers. | James T Taylor Xiang-Bin Zeng Jonathan E Pottle Kevin Lee Alun R Wang Stephenie G Yi lennifer A S Scruggs Suresh S Sikka Ming Li | 2008 | World Journal of Gastroenterology2008，14，32： | 12 |
| 6 | Species of Botryosphaeriaceae involved in grapevine dieback in China显示文摘Botryosphaeria dieback is a serious disease problem for table and grape wine production worldwide.The disease however,has been less well-studied in China.In this study,we surveyed Botryosphaeria dieback in 72 vineyards of 20 grape-growing regions in China and found that Botryosphaeria dieback occurs in 18 out of 20 provinces.Morphological and multi-gene phylogenetic analyses confirmed that Botryosphaeria dothidea,Diplodia seriata,Lasiodiplodia theobromae and Neofusicoccum parvum are associated with different grapevine dieback symptoms.This study also revealed considerable differences in the geographical distribution of Botryosphaeriaceae species in China with Lasiodiplodia theobromae and Neofusicoccum parvum occurring only in subtropical monsoon climate regions,Diplodia seriata occurring only in temperate monsoon climate regions,and Botryosphaeria dothidea occurring in both temperate and subtropical monsoon climate regions.Analysis of 26 isolates showed that there is little genetic variation within species.Koch’s postulates were satisfied for all species,and pathogenicity testing showed that among the 25 major cultivars growing in China,none was resistant to the four taxa.The current paper represents the first detailed report on Botryosphaeria dieback of grapevines in China. | Ji-Ye Yan Yue Xie Wei Zhang Yong Wang Jian-Kui Liu Kevin D.Hyde Robert C.Seem Guo-Zhen Zhang Zhong-Yue Wang Sheng-Wei Yao Xian-Jin Bai Asha J.Dissanayake You-Liang Peng Xing-Hong Li | 2013 | Fungal Diversity2013，，4： | 11 |
| 7 | Review of the biological and engineering aspects of algae to fuels approach显示文摘Current biofuel production relies on limited arable lands on the earth,and is impossible to meet the biofuel demands.Oil producing algae are alternative biofuel feedstock with potential to meet the world’s ambitious goal to replace fossil fuels.This review provides an overview of the biological and engineering aspects in the production and processing technologies and recent advances in research and development in the algae to fuels approach.The article covers biology,selection and genetic modification of algae species and strains,production systems design,culture media and light management,harvest and dewatering,downstream processing,and environment and economic assessment.Despite the many advances made over several decades,commercialization of algal fuels remains challenging chiefly because of the techno-economic constraints.Technological breakthroughs in all major aspects must take place before commercial production of algal fuels becomes economically viable. | Paul Chen Min Min Yifeng Chen Liang Wang Yecong Li Qin Chen Chenguang Wang Yiqin Wan Xiaoquan Wang Yanling Cheng Shaobo Deng Kevin Hennessy Xiangyang Lin Yuhuan Liu Yingkuan Wang Blanca Martinez Roger Ruan | 2009 | International Journal of Agricultural and Biological Engineering2009，2，4： | 9 |
| 8 | 行波光电二极管级联阵列输出功率合成研究显示文摘针对未来光载无线通信所需的高功率、大带宽的光电探测器,提出了一种行波光电二极管级联阵列功率合成电路.先将行波光电二极管级联,再按照阵列式结构将多组级联的光电二极管组合起来,实现射频功率合成,以获得高功率、大带宽的射频信号.采用EDA工具,对该光电转换射频功率合成电路进行仿真模拟.仿真结果表明,该功率合成电路可以有效地将各光电二极管的射频输出信号进行功率合成,功率合成后的信号带宽显著增加,仿真结果与理论分析完全一致.此外,电路分析表明,增加该功率合成电路中的高阻微带线的特性阻抗可以有效提高其输出射频信号的带宽. | 文化锋 聂秋华 刘太君 徐铁峰 应祥岳 CLARK Kevin LI Ying-feng | 2015 | 光子学报2015，44，3： | 7 |
| 9 | Digital synthesis of histological stains using micro-structured and multiplexed virtual staining of label-free tissue显示文摘Histological staining is a vital step in diagnosing various diseases and has been used for more than a century to provide contrast in tissue sections,rendering the tissue constituents visible for microscopic analysis by medical experts.However,this process is time consuming,labour intensive,expensive and destructive to the specimen.Recently,the ability to virtually stain unlabelled tissue sections,entirely avoiding the histochemical staining step,has been demonstrated using tissue-stain-specific deep neural networks.Here,we present a new deep-learning-based framework that generates virtually stained images using label-free tissue images,in which different stains are merged following a micro-structure map defined by the user.This approach uses a single deep neural network that receives two different sources of information as its input:(1)autofluorescence images of the label-free tissue sample and(2)a“digital staining matrix”,which represents the desired microscopic map of the different stains to be virtually generated in the same tissue section.This digital staining matrix is also used to virtually blend existing stains,digitally synthesizing new histological stains.We trained and blindly tested this virtual-staining network using unlabelled kidney tissue sections to generate micro-structured combinations of haematoxylin and eosin(H&E),Jones’silver stain,and Masson’s trichrome stain.Using a single network,this approach multiplexes the virtual staining of label-free tissue images with multiple types of stains and paves the way for synthesizing new digital histological stains that can be created in the same tissue cross section,which is currently not feasible with standard histochemical staining methods. | Yijie Zhang Kevin de Haan Yair Rivenson Jingxi Li Apostolos Delis Aydogan Ozcan | 2020 | Light(Science & Applications)2020，9，1： | 7 |
| 10 | Distributional responses to climate change for alpine species of Cyananthus and Primula endemic to the Himalaya-Hengduan Mountains显示文摘Global warming increases the vulnerability of plants, especially alpine herbaceous species, to local extinction. In this study, we collected species distribution information from herbarium specimens for ten selected Cyananthus and Primula alpine species endemic to the Himalaya-Hengduan Mountains(HHM).Combined with climate data from WorldClim, we used Maximum Entropy Modeling(MaxEnt) to project distributional changes from the current time period to 2070. Our predictions indicate that, under a wide range of climate change scenarios, the distributions of all species will shift upward in elevation and northward in latitude; furthermore, under these scenarios, species will expand the size of their range. For the majority of the species in this study, habitats are available to mitigate upward and northward shifts that are projected to be induced by changing climate. If current climate projections, however, increase in magnitude or continue to increase past our projection dates, suitable habitat for future occupation by alpine species will be limited as we predict range contraction or less range expansion for some of the species under more intensified climate scenarios. Our study not only underscores the value of herbarium source information for future climate model projections but also suggests that future studies on the effects of climate change on alpine species should include additional biotic and abiotic factors to provide greater resolution of the local dynamics associated with species persistence under a warming climate. | Xie He Kevin S. Burgess Lian-Ming Gao De-Zhu Li | 2019 | Plant Diversity2019，41，1： | 7 |
| 11 | A Review of Technical Advances,Barriers,and Solutions in the Power to Hydrogen(P2H)Roadmap显示文摘Power to hydrogen(P2H)provides a promising solution to the geographic mismatch between sources of renewable energy and the market,due to its technological maturity,flexibility,and the availability of technical and economic data from a range of active demonstration projects.In this review,we aim to provide an overview of the status of P2H,analyze its technical barriers and solutions,and propose potential opportunities for future research and industrial demonstrations.We specifically focus on the transport of hydrogen via natural gas pipeline networks and end-user purification.Strong evidence shows that an addition of about 10%hydrogen into natural gas pipelines has negligible effects on the pipelines and utilization appliances,and may therefore extend the asset value of the pipelines after natural gas is depleted.To obtain pure hydrogen from hydrogen-enriched natural gas(HENG)mixtures,end-user separation is inevitable,and can be achieved through membranes,adsorption,and other promising separation technologies.However,novel materials with high selectivity and capacity will be the key to the development of industrial processes,and an integrated membrane-adsorption process may be considered in order to produce high-purity hydrogen from HENG.It is also worth investigating the feasibility of electrochemical separation(hydrogen pumping)at a large scale and its energy analysis.Cryogenics may only be feasible when liquefied natural gas(LNG)is one of the major products.A range of other technological and operational barriers and opportunities,such as water availability,byproduct(oxygen)utilization,and environmental impacts,are also discussed.This review will advance readers’understanding of P2H and foster the development of the hydrogen economy. | Guoping Hu Chao Chen Hiep Thuan Lu Yue Wu Congmin Liu Lefu Tao Yuhan Men Guangli He Kevin Gang Li | 2020 | Engineering2020，6，12： | 7 |
| 12 | A DEA-TOPSIS METHOD FOR MULTIPLE CRITERIA DECISION ANALYSIS IN EMERGENCY MANAGEMENT显示文摘A hybrid approach of DEA (data envelopment analysis) and TOPSIS (technique for order performance (preference) by similarity to ideal solution) is proposed for multiple criteria decision analysis in emergency management.Two DEA-based optimization models are constructed to facilitate identifying parameter information regarding criterion weights and quantifying qualitative criteria in TOPSIS.An emergency management case study utilizing data from the Emergency Management Australia (EMA) Disasters Database is provided to demonstrate the feasibility of the proposed analysis procedure. | Ye CHEN Kevin W. LI Haiyan XU Sifeng LIU | 2009 | Journal of Systems Science and Systems Engineering2009，18，4： | 6 |
| 13 | 粉煤灰合成沸石及其在重金属废水处理中的应用显示文摘以粉煤灰为原料,经碱溶液处理后,晶化得到沸石类产品。样品进行XRD,N2吸附脱附,SEM等技术进行表征。XRD结果表明该方法可以合成得到P型沸石的晶型结构;N2吸附脱附结果显示样品的BET约30~50cm2/g,与原粉煤灰相比有显著提高;SEM结果表明在粉煤灰玻璃球体表面长出沸石类的多孔结构。将该方法得到的一系列样品用于含有500ppm Ni2+的模拟重金属废水中,表明该材料具有很好的重金属处理效果,饱和吸附量在20~50mg/g,达到商业沸石处理水平,具有很好的市场应用空间。 | 于家琳 杨阳 Kevin Li 徐冬 郭桦 刘汉强 | 2016 | 粉煤灰综合利用2016，0，2： | 6 |
| 14 | The RppC-AvrRppC NLR-effector interaction mediates the resistance to southern corn rust in maize显示文摘Southern corn rust(SCR),caused by the fungal pathogen Puccinia polysora,is a major threat to maize pro-duction worldwide.Efficient breeding and deployment of resistant hybrids are key to achieving durable control of SCR.Here,we report the molecular cloning and characterization of RppC,which encodes an NLR-type immune receptor and is responsible for a major SCR resistance quantitative trait locus.Further-more,we identified the corresponding avirulence effector,AvrRppC,which is secreted by P.polysora and triggers RppC-mediated resistance.Allelic variation of AvrRppC directly determines the effectiveness of RppC-mediated resistance,indicating that monitoring of AvrRppC variants in the field can guide the rational deployment of RppC-containing hybrids in maize production.Currently,RppC is the most frequently deployed SCR resistance gene in China,and a better understanding of its mode of action is crit-ical for extending its durability. | Ce Deng April Leonard James Cahill Meng Lv Yurong Li Shawn Thatcher Xueying Li Xiaodi Zhao Wenjie Du Zheng Li Huimin Li Victor Llaca Kevin Fengler Lisa Marshall Charlotte Harris Girma Tabor Zhimin Li Zhiqiang Tian Qinghua Yang Yanhui Chen Jihua Tang Xintao Wang Junjie Hao Jianbing Yan Zhibing Lai Xiaohong Fei Weibin Song Jinsheng Lai Xuecai Zhang Guoping Shu Yibo Wang Yuxiao Chang Weiling Zhu Wei Xiong Juan Sun Bailin Li Junqiang Ding | 2022 | Molecular Plant2022，15，5： | 6 |
| 15 | Inferring the Tree of Life of the order Cypriniformes, the earth's most diverse clade of freshwater fishes: Implications of varied taxon and character sampling显示文摘The phylogenetic relationships of species are fundamental to any biological investigation, including all evolutionary studies. Accurate inferences of sister group relationships provide the researcher with an historical framework within which the attributes or geographic origin of species (or supraspecific groups) evolved. Taken out of this phylogenetic context, interpretations of evolutionary processes or origins, geographic distributions, or speciation rates and mechanisms, are subject to nothing less than a biological experiment without controls. Cypriniformes is the most diverse clade of freshwater fishes with estimates of diversity of nearly 3,500 species. These fishes display an amazing array of morphological, ecological, behavioral, and geographic diversity and offer a tremendous opportunity to enhance our understanding of the biotic and abiotic factors associated with diversification and adaptation to environments. Given the nearly global distribution of these fishes, they serve as an important model group for a plethora of biological investigations, including indicator species for future cli-matic changes. The occurrence of the zebrafish, Danio rerio, in this order makes this clade a critical component in understanding and predicting the relationship between mutagenesis and phenotypic expressions in vertebrates, including humans. With the tremendous diversity in Cypriniformes, our understanding of their phylogenetic relationships has not proceeded at an acceptable rate, despite a plethora of morphological and more recent mo-lecular studies. Most studies are pre-Hennigian in origin or include relatively small numbers of taxa. Given that analyses of small numbers of taxa for molecular characters can be compromised by peculiarities of long-branch attraction and nodal-density effect, it is critical that significant progress in our understanding of the relationships of these important fishes occurs with increasing sampling of species to mitigate these potential problems. The recent Cypriniformes Tree of Life initiative is an effort to achieve this goal with morphological and molecular (mitochondrial and nuclear) data. In this early synthesis of our understanding of the phylogenetic relationships of these fishes, all types of data have contributed historically to improving our understanding, but not all analyses are complementary in taxon sampling, thus precluding direct understanding of the impact of taxon sampling on achieving accurate phylogenetic inferences. However, recent molecular studies do provide some insight and in some instances taxon sampling can be implicated as a variable that can influence sister group relationships. Other instances may also exist but without inclusion of more taxa for both mitochondrial and nuclear genes, one cannot distinguish between inferences being dictated by taxon sampling or the origins of the molecular data. | Richard L. MAYDEN Kevin L. TANG Robert M. WOOD Wei-Jen CHEN Mary K. AGNEW Kevin W. CONWAY Lei YANG Andrew M. SIMONS Henry L. BART Phillip M. HARRIS Junbing LI Xuzhen WANG Kenji SAITOH Shunping HE Huanzhang LIU Yiyu CHEN Mutstmi NISHIDA Masaki MIYA | 2008 | 植物分类学报2008，46，3： | 5 |
| 16 | Automated defect analysis in electron microscopic images显示文摘Electron microscopy and defect analysis are a cornerstone of materials science,as they offer detailed insights on the microstructure and performance of a wide range of materials and material systems.Building a robust and flexible platform for automated defect recognition and classification in electron microscopy will result in the completion of analysis orders of magnitude faster after images are recorded,or even online during image acquisition.Automated analysis has the potential to be significantly more efficient,accurate,and repeatable than human analysis,and it can scale with the increasingly important methods of automated data generation.Herein,an automated recognition tool is developed based on a computer vison–based approach;it sequentially applies a cascade object detector,convolutional neural network,and local image analysis methods.We demonstrate that the automated tool performs as well as or better than manual human detection in terms of recall and precision and achieves quantitative image/defect analysis metrics close to the human average.The proposed approach works for images of varying contrast,brightness,and magnification.These promising results suggest that this and similar approaches are worth exploring for detecting multiple defect types and have the potential to locate,classify,and measure quantitative features for a range of defect types,materials,and electron microscopic techniques. | Wei Li Kevin G.Field Dane Morgan | 2018 | npj Computational Materials2018，，1： | 5 |
| 17 | Gut microbiota mediated molecular events and therapy in liver diseases显示文摘Gut microbiota is a community of microorganisms that reside in the gastrointestinaltract. An increasing number of studies has demonstrated that the gutliveraxis plays a critical role in liver homeostasis. Dysbiosis of gut microbiota cancause liver diseases, including nonalcoholic fatty liver disease and alcoholic liverdisease. Preclinical and clinical investigations have substantiated that themetabolites and other molecules derived from gut microbiota and diet interactionfunction as mediators to cause liver fibrosis, cirrhosis, and final cancer. This effecthas been demonstrated to be associated with dysregulation of intrahepaticimmunity and liver metabolism. Targeting these findings have led to thedevelopment of novel preventive and therapeutic strategies. Here, we review thecellular and molecular mechanisms underlying gut microbiota-mediated impacton liver disease. We also summarize the advancement of gut microbiota-basedtherapeutic strategies in the control of liver diseases. | Xiaoqiang Qi Ming Yang Joseph Stenberg Rahul Dey Leslie Fogwe Muhammad Shawkat Alam Eric TKimchi Kevin F Staveley-O'Carroll Guangfu Li | 2020 | World Journal of Gastroenterology2020，26，48： | 5 |
| 18 | Impact of time to surgery from injury on postoperative infection and deep vein thrombosis in periprosthetic knee fractures显示文摘Purpose:Periprosthetic fracture (PPF) is a serious complication that occurs in 0.3%-2.5% of all total knee arthroplasties used to treat end-stage arthritis. To our knowledge, there are no studies in the literature that evaluate the association between time to surgery after PPF and early postoperative infections or deep vein thrombosis (DVT). This study tests our hypothesis that delayed time to surgery increases rates of postoperative infection and DVT after PPF surgery.Methods:Our study cohort included patients undergoing PPF surgery in the American College of Surgeons National Surgical Quality Improvement Program database (2006-2015). The patients were dichotomized based on time to surgery: group 1 with time ≤2 days and group 2 with time >2 days. A 2-by-2 contingency table and Fisher's exact test were used to evaluate the association between complications and time to surgery groups, and multivariate logistic regression was used to adjust for demographics and known risk factors.Results:A total of 263 patients (80% females) with a mean age of 73.9 ± 12.0 years were identified receiving PPF surgery, among which 216 patients were in group 1 and 47 patients in group 2. Complications in group 1 included 3 (1.4%) superficial infections (SI), 1 (0.5%) organ space infection (OSI), 1 (0.5%) wound dehiscence (WD), and 4 (1.9%) deep vein thrombosis (DVT);while complications in group 2 included 1 (2.1%) SI, 1 (2.1%) OSI, 1 (2.1%) DVT, and no WD. No significant difference was detected in postoperative complications between the two groups. However, patients in group 2 were more likely (p = 0.0013) to receive blood transfusions (57.5%) than those in group 1 (32.4%).Conclusion:Our study indicates patients with delayed time to surgery have higher chance to receive blood transfusions, but no significant difference in postoperative complications (SI, OSI, WD, or DVT) between the two groups. | Sung Ro Lee Kevin Shrestha Jackson Staggers Peng Li Sameer M.Naranje Ashish Shah | 2018 | Chinese Journal of Traumatology2018，21，6： | 5 |
| 19 | Air quality monitoring using mobile microscopy and machine learning显示文摘Rapid,accurate and high-throughput sizing and quantification of particulate matter(PM)in air is crucial for monitoring and improving air quality.In fact,particles in air with a diameter of≤2.5μm have been classified as carcinogenic by the World Health Organization.Here we present a field-portable cost-effective platform for high-throughput quantification of particulate matter using computational lens-free microscopy and machine-learning.This platform,termed c-Air,is also integrated with a smartphone application for device control and display of results.This mobile device rapidly screens 6.5 L of air in 30 s and generates microscopic images of the aerosols in air.It provides statistics of the particle size and density distribution with a sizing accuracy of~93%.We tested this mobile platform by measuring the air quality at different indoor and outdoor environments and measurement times,and compared our results to those of an Environmental Protection Agency–approved device based on beta-attenuation monitoring,which showed strong correlation to c-Air measurements.Furthermore,we used c-Air to map the air quality around Los Angeles International Airport(LAX)over 24 h to confirm that the impact of LAX on increased PM concentration was present even at 47 km away from the airport,especially along the direction of landing flights.With its machinelearning-based computational microscopy interface,c-Air can be adaptively tailored to detect specific particles in air,for example,various types of pollen and mold and provide a cost-effective mobile solution for highly accurate and distributed sensing of air quality. | Yi-Chen Wu Ashutosh Shiledar Yi-Cheng Li Jeffrey Wong Steve Feng Xuan Chen Christine Chen Kevin Jin Saba Janamian Zhe Yang Zachary Scott Ballard Zoltán Göröcs Alborz Feizi Aydogan Ozcan | 2017 | Light(Science & Applications)2017，6，1： | 5 |
| 20 | Phyllosticta species associated with citrus diseases in China显示文摘Phyllosticta species associated with diseases of four commercial Citrus species grown in China are reported.Totally,496 Phyllosticta strains were isolated from mandarins(Citrus reticulata),pomeloes(C.maxima),oranges(C.sinensis)and lemons(C.limon)in the main citrus producing regions across China,and 74 strains were selected for phylogenetic analysis.Analyses inferred from the sequences of internal transcribed spacer region(ITS1,5.8S nrDNA and ITS2),partial translation elongation factor 1-alpha(TEF1)and partial actin gene(ACT),showed these representative Phyllosticta isolates clustered in four distinct clades corresponding to three known,and one undescribed species.The newly resolved taxon,Phyllosticta citrichinaensis was isolated from leaves and fruits of all four Citrus species and is introduced in this paper.This taxon caused minor damage,showing irregular spots or freckles.Phyllosticta citriasiana,associated with tan spot of pomeloes,was isolated only from pomeloes,and never from lemons,mandarins and oranges.Phyllosticta citricarpa,the citrus black spot pathogen,which is presently subjected to phytosanitary legislation in the EU and United States,was isolated from lemons,mandarins and oranges,but never from pomeloes.The isolates of P.citricarpa clustered in two subclades,one from mandarins,the other from oranges and lemons.P.capitalensis was isolated from all four Citrus species as an endophyte,causing false melanose,or together with P.citricarpa or P.citriasiana.Morphological,cultural and biochemical characters were consistent with the results of phylogenetic analysis.In addition,a specific primer pair Pca8/ITS4 was designed and selected,and its corresponding PCR procedure was developed for the detection of P.citriasiana in this study. | Xinghong Wang Guoqing Chen Feng Huang Jingze Zhang Kevin D.Hyde Hongye Li | 2012 | Fungal Diversity2012，，1： | 5 |
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