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| 1 | Experimental study of“Tong Xia”purgative method in ameliorating lung injury in acute necrotizing pancreatitis显示文摘AIM To investigate the role of tumor necrosisfactor(TNF)in lung injury during acutenecrotizing pancreatitis(ANP),and thetherapeutic effect of'Tong Xia'purgativemethod in minimizing the severity of lung injury.METHODS Fourteen canines were randomlydivided into 3 groups:the'Tong Xia'treatmentgroup(n = 5)using Dachengqitang;salinecontrol group(n = 5),and the sham operationgroup(n = 4).TNF activity in serum and inbronchoalveolar lavage fluid(BALF),the serumendotoxin levels were measured,and theseverity of lung injury evaluated.RESULTS Elevation of TNF activity was moreprominent in BALF than in serum.TNF activity inserum at 6 and 12 hours and in BALI:wassignificantly decreased in the'Tong Xia'treatment group than in the saline control one(q=21.11,q=12.07,q=9.03,respectively,P<0.01)and the lung injury was significantlyalleviated at 12 hours as compared with that inthe saline group,manifested as amelioration otthe lung wet/ dry weight ratio,decrease inprotein concentration and neutrophils count inBALF,and improvement of pulmonaryinflammatory changes.A positive correlationwas demonstrated between serum TNF activity and endotoxin level.CONCLUSION Hypersecretion of TNF is shownto be one of the major causes of lung injuryduring ANP;'Tong Xia'purgative method couldalleviate the degree of lung injury mediated byTNF. | Xia Q Jiang JM Gong X Chen GY Li L Huang ZW | 2000 | World Journal of Gastroenterology2000，6，1： | 31 |
| 2 | The first internal-tide deposits found in China显示文摘NOT until Gao Zhenzhong and Eriksson studied the Ordovician of Fincastle area, Appalachi-ans, the USA in 1990, did sedimentologist recognize internal-tide deposits in the ancientrecord and begin to use the term of 'internal-tide deposit'. In the Ordovician of Fincastlearea, two facies are recognized: (i) bidirectional cross-laminated very fine grained | Gao, ZZ He, YB Li, JM Li, WF Luo, SS Wang, ZZ | 1997 | Chinese Science Bulletin1997，42，13： | 5 |
| 3 | 急性病毒性肝炎的全球负担及其与社会经济发展状态的关系(1990—2019)显示文摘【据Journal of Hepatology 2021年5月报道】题:急性病毒性肝炎的全球负担及其与社会经济发展状态的关系(1990—2019)(作者Zeng DY等)急性病毒性肝炎(AVH)是全球重要的公共卫生健康问题,但由于全球病毒性肝炎防治重心在于后果严重的慢性乙型肝炎(CHB)以及慢性丙型肝炎(CHC),而关于AVH的研究进展有限。随着最近针对病毒性肝炎的疫苗和治疗方法的进展,需要对AVH的负担进行更深入的了解,从而为全球干预策略提供依据。来自福建医科大学第一附属医院肝病科的Zeng等通过全球疾病负担2019数据库(Global Burden of Disease Study 2019)收集4种主要AVH类型的年龄标准化发病率和伤残调整生命年(DALY)率数据,包括A、B、C和E型急性肝炎,并将数据以性别、社会人口指数(SDI)水平、国家和地区进行分层,描述社会经济发展状态(以SDI为代表)与AVH负担的关联性。 | ZENG DY LI JM LIN S | 2021 | 临床肝胆病杂志2021，37，6： | 4 |
| 4 | 肠道微生态失调与高血压的关系显示文摘新出现的证据表明,肠道菌群是维持生理动态平衡的关键,该研究旨在验证微生态失衡的肠道菌群与高血压相关这一假设,因为遗传、环境和膳食因素对肠道菌群和血压有很大影响。方法:从2种高血压模型大鼠和一个小队列患者人群的粪便样本中提取细菌DNA,用于细菌基因组的分析. | 刘莉 叶鹏 Yang T Santisteban MM Rodriguez V Li E Ahmari N Carvajal JM Zadeh M Gong M Qi Y Zubcevic J Sahay B Pepine CJ Raizada MK Mohamadzadeh M | 2015 | 中华高血压杂志2015，23，5： | 4 |
| 5 | Phytoremediation of soil metals显示文摘 | Rufus L Chaney Minnie Malik Yin M Li Sally L Brown Eric P Brewer J Scott Angle Alan JM Baker | 1997 | Current Opinion in Biotechnology1997，，3： | 2 |
| 6 | Thermodynamic Aspect in Synthesis of AlN Powders by Carbothermal Reduction and Nitridation Process显示文摘A thermodynamical calculation shows that AlN powders were synthesized in the process bythe overall reaction Al2O3(s)+3C(s)+N2(g)=2AlN(s)+3CO(g) and its minimum reaction tem-perature T0=1852 K, if all reactants and products were in standard states. ln the practicalexperiments, AlN phase appeared obviously at only 1300℃, the major reasons are related to thepartial pressure of its gaseous product pco and the mixed free energy. The synthesis temperaturecould be lowered by either increasing N2 flow rate or elevating N2 pressure. On the other hand,as the temperature decreases, the equilibrium constant Km also reduces, and the reducing ratestrongly depends on the temperature: the lower the temperature, the higher the rate. | Dai, XM Li, QF Ding, MQ Tian, JM | 1999 | Journal of Materials Science & Technology1999，15，1： | 2 |
| 7 | Nrf2, a multi organ protector 显示文摘 | Lee JM Li J Johnson DA | 2005 | FASEB J2005，19，9： | 1 |
| 8 | CT features of pulmonary alveolar proteinosis显示文摘 | Holbert JM Costello P Li W | 2001 | Am J Roentgenol2001，176，5： | 1 |
| 9 | Nrf2,a multi-organ protector?显示文摘 | LEE JM LI J JOHNSON DA | 2005 | FASEB J2005，19，9： | 1 |
| 10 | Antisense oligonucleotide targeting the transforming growth factor β1 increases expression of specific genes and functions of Leydig cells显示文摘 | Roy CL Leduque P Li JY Seaz JM Langlois D | 1998 | Eur J Biochem1998，257，2： | 1 |
| 11 | Nematophin, a novel antimicrobial substance produced by Xenorhabdus nematophilus (Enterobactereaceae) 显示文摘 | Li JX Chen GH Webster JM | 1997 | Can J Microbiol1997，43，： | 1 |
| 12 | Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development显示文摘 | Li F Wang X Capasso JM | 1996 | J Mol Cell cardiol1996，28，8： | 1 |
| 13 | Contact-dependent stimulation of monocytic cells and neutrophils by stimulated human T-cell clones显示文摘 | Li JM Isler P Dayer JM | 1995 | Immunology1995，84，： | 1 |
| 14 | Dissimilar immunogenicities ofhuman papillomavirus E7 and adenovirus E1A proteins influenceprimary tumor development显示文摘 | Routes JM Ryan S Li H | 2000 | Virology2000，277，1： | 1 |
| 15 | The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by mi-croRNAs显示文摘 | Abrahante JE Daul AL Li M Volk ML Tennessen JM MillerEA | 2003 | Dev Cell2003，4，5： | 1 |
| 16 | Hypoxia inducible factors in cancer stem cells显示文摘 | Heddlestan JM Li Z Lathia JD | 2010 | Br J Cancer2010，102，5： | 1 |
| 17 | Analysis of the fungi community in multiple- and single-grains Zaopeifrom a Luzhou-flavor liquor distillery in western China 显示文摘 | Shi S Zhang L Wu ZY Zhang WX Deng Y Zhong FD Li JM | 2011 | World JMicrobiol Biotechnol2011，27，： | 1 |
| 18 | Combinatorial modification of multiple lignin traits in trees through multigene cotransformation 显示文摘 | Li L Zhou Y Cheng X Sun J Marita JM Ralph J Chiang VL | 2003 | Proc Natl Acad Sci USA2003，100，8： | 1 |
| 19 | How to manage acute promyelocytic leukemia显示文摘 | Mi JQ Li JM Shen ZX | 2012 | Leukemia2012，26，8： | 1 |
| 20 | Confidentidentification of 3-nitrotyrosine modifications in massspectral data across multiple mass spectrometryplatforms显示文摘 | Li B Held JM Schilling B | 2011 | J Proteomics2011，74，： | 1 |
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