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| 1 | Brain metastasis of hepatocellular carcinoma:A case report and review of the literature显示文摘Hepatocellular carcinoma (HCC) is one of the most frequent malignancies in the world. It is more common in far eastern countries and relatively rare in the United States and western European countries where at autopsy it accounts for only 1-2% of malignant rumors, The disease is usually manifested in the the 6^th and 7^th decade of life. HCC is one of the highly malignant neoplasms, Extrahepatic metastases are seen in 64% of patients with HCC. The lungs, regional lymph nodes, kidney, bone marrow and adrenals are common sites of HCC metastasis^[1-3], But, metastasis to brain and skull is extremely rare. Table I shows some of the reported cases of HCC with brain metastasis. These case reports reaffirms the complex and multidisciplinary care of these patients^[4-5]. | Bilge Tunc Levent Filik Irsel Tezer-Filik Burhan Sahin | 2004 | World Journal of Gastroenterology2004,10,11: | 4 |
| 2 | Association between Helicobacter pylori and liver-to-spleen ratio: a randomized-controlled single-blind study显示文摘 | Zeynal Do?an Levent Filik Bilal Ergül Murat Sarikaya Erdem Akbal | 2013 | European Journal of Gastroenterology & Hepatology2013,,1: | 3 |
| 3 | The Efficacy of Two‐Week Quadruple First‐Line Therapy with Bismuth, Lansoprazole, Amoxicillin, Clarithromycin on H elicobacter pylori Eradication: A Prospective Study显示文摘 | Bilal Ergül Zeynal Do?an Murat Sarikaya Levent Filik | 2013 | Helicobacter2013,,6: | 2 |
| 4 | Effect of interferon and ribavirin combined with amantadine in interferon and ribavirin non-responder patients with chronic hepatitis C (genotype 1)显示文摘AIM: To evaluate the efficacy of amantadine plus interferonalpha and ribavirin in non-responder patients with chronic hepatitis C.METHODS: Twenty-six non-responder patients received the regimen of IFN-α-2a at a dose of 6 million units three times a week, 1 000-1 200 mg of ribavirin daily, and 200 mg of amantadine daily in divided doses over 48 wk. After the end of treatment, at the 72nd wk, a sustained viral response rate was determined.RESULTS: An early (after 12 wk of therapy) response was seen in 34.6% (9/26) of patients. Response rate at the 24th wk was 42.3% (11/26). End of treatment response (ETR) was 53.8% (14/26). Sustained viral response (SVR) was 42.3% (11/26). There was a statistically significant difference between 0 and 12 wk (P = 0.04), 0 and 24 wk (P = 0.01), 0 and 48 wk (P = 0.00), and 0 and 72 wk (P = 0.001). No patient had severe adverse effects during the treatment.CONCLUSION: Combination regimen of interferon-α,ribavirin and amantadine can enhance sustained viral response on IFN-α and ribavirin non-responder patients with HCV. Triple therapy with amantadine should be evaluated in further studies. | Dilek Oguz Bahattin Cicek Levent Filik Bulent Odemis Mesut Kilic Engin Altintas Neslihan Zengin Emin Altiparmak | 2005 | World Journal of Gastroenterology2005,11,4: | 1 |
| 5 | Monocyte chemotactic protein-1 gene polymorphism and spontaneous bacterial peritonitis显示文摘I read with great interest the article by Gbele et al published in issue 44 of World J Gastroenterol 2009.The results of their study indicate that-2518 Monocyte chemotactic protein-1(MCP-1)genotype AA is a risk factor for spontaneous bacterial peritonitis in patients with alcoholic cirrhosis.However,there are some items that need to be discussed. | Levent Filik | 2010 | World Journal of Gastroenterology2010,16,7: | 1 |
| 6 | Differentiation of Behcet's disease from inflammatory bowel diseases:Anti-saccharomyces cerevisiae antibody and anti-neutrophilic cytoplasmic antibody显示文摘The differential diagnosis of Behcet's disease(BD) from inflammatory bowel disease(IBD) is sometimes difficult and challenging.Hereby,we suggested the utility of anti-saccharomyces cerevisiae antibody(ASCA) and anti-neutrophilic cytoplasmic antibody(p-ANCA) in the differential diagnosis of BD from IBD. | Levent Filik Ibrahim Biyikoglu | 2008 | World Journal of Gastroenterology2008,14,47: | 1 |
| 7 | Association between Helicobacter pylori and liver-to-spleen ratio: a randomized-controlled single-blind study显示文摘 | Zeynal Do?an Levent Filik Bilal Ergül Murat Sarikaya Erdem Akbal | 2013 | European Journal of Gastroenterology & Hepatology2013,,1: | 1 |
| 8 | Acute pancreatitis induced by Viburnum opulus juice in a patient with urolithiasis显示文摘Dear editorViburnum opulus(V.opulus) is a common plathroughout the world especially grown in EuropNorthern Africa and Asia[1].It is used usually homeopathy to reduce smooth muscle tightness relieve general muscle cramping or women’s menstrcramps[1,2].It also is given for prevention and treatmeof urolithiasis.However,there is no enough data | Zuhal Dag Galip Akturk Levent Filik | 2014 | Asian Pacific Journal of Tropical Biomedicine2014,4,10: | 0 |