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| 1 | Risk factors for colonoscopic perforation: A population-based study of 80118 cases显示文摘AIM: To assess the incidence and risk factors associated with colonic perforation due to colonoscopy. METHODS: This was a retrospective cross-sectional study. Patients were retrospectively eligible for inclusion if they were 18 years and older and had an inpatient or outpatient colonoscopy procedure code in any facility within the Geisinger Health System during the period from January 1, 2002 to August 25, 2010. Data are presented as median and inter-quartile range, for continuous variables, and as frequency and percentage for categorical variables. Baseline comparisons across those with and without a perforation were made using the two-sample t -test and Pearson's χ2 test, as appropriate.RESULTS: A total of 50 perforations were diagnosed out of 80118 colonoscopies, which corresponded to an incidence of 0.06% (95%CI: 0.05-0.08) or a rate of 6.2 per 10000 colonoscopies. All possible risk factors associated with colonic perforation with a P -value < 0.1 were checked for inclusion in a multivariable logbinomial regression model predicting 7-d colonic perforation. The final model resulted in the following risk factors which were significantly associated with risk of colonic perforation: age, gender, body mass index, albumin level, intensive care unit (ICU) patients, inpatient setting, and abdominal pain and Crohn's disease as indications for colonoscopy. CONCLUSION: The cumulative 7 d incidence of colonic perforation in this cohort was 0.06%. Advanced age and female gender were significantly more likely to have perforation. Increasing albumin and BMI resulted in decreased risk of colonic perforation. Having a colonoscopy indication of abdominal pain or Crohn's disease resulted in a higher risk of colonic perforation. Colonoscopies performed in inpatients and particularly the ICU setting had substantially greater odds of perforation. Biopsy and polypectomy did not increase the risk of perforation and only three perforations occurred with screening colonoscopy. | Uzair Hamdani Raza Naeem Fyeza Haider Pardeep Bansal Michael Komar David L Diehl H Lester Kirchner | 2013 | World Journal of Gastroenterology2013，19，23： | 9 |
| 2 | Comparison between hepaticojejunostomy and hepaticoduodenostomy after excision of choledochal cyst in children:a cohort study显示文摘Objective Hepaticojejunostomy(HJ)and hepaticoduodenostomy(HD)are commonly used biliary reconstruction techniques after choledochal cyst excision.HD has been suggested to be a more physiologic alternative during reconstruction.The objective of this study is to compare operative time,hospital stay,morbidity(leak,cholangitis,ileus,and obstruction),and mortality between HJ and HD after cyst excision.Methods This is a 14-year retrospective cohort study of pediatric patients(≤18 years old)who underwent choledochal cyst excision and subsequent biliary reconstruction at the Philippine Children’s Medical Center.Data were taken from inpatient charts,operative technique,OPD logbook,readmission,and OPD charts.results There were 122 patients:56%HD and 44%HJ.Majority were female(72%),with 1:2.6 male to female ratio.The average age was 36.1 months,with a mean follow-up of 32.8 months(range 6 months-14 years).The most common cyst was type I(87%).Operative time was longer for HJ compared with HD(321.3 vs 203.6 min;p=0.000).Hospital stay was longer with HJ compared with HD(7.7 vs 6.8 days;p=0.002).Mortality rate was low at 1.6%while morbidity was at 13.9%in both groups.Although morbidity was higher among those who underwent HD,there was no significant difference between the two procedures.Anastomotic leak(4%)and cholangitis(7.4%)were observed in HD,and ileus(7.4%)was observed in the HJ group.Conclusions In our series,HD provided less operative time and hospital stay than with HJ.We did not observe bile gastritis after HD as compared with others.It is suggested that longer follow-up is needed to confirm such findings. | Johann Paulo Suico Guzman Leandro L Resurreccion III Marcus Lester R Suntay Renato G Bernaldez | 2019 | World Journal of Pediatric Surgery2019，2，2： | 2 |
| 3 | ACE I/D poly- morphism study in a Cuban hypertensive population 显示文摘 | Osmel CN Miguel S C Lester L | 2007 | Clin Chim Acta2007，378，12： | 1 |
| 4 | Photopolymerizationkinetics and structure development of templated lyotropic liquidcrystalline systems显示文摘 | LESTER C L COLSON C D GUYMON C A | 2001 | Macromolecules2001，34，13： | 1 |
| 5 | Customer Loyalty to One Service Worker:Should It be Discouraged?显示文摘 | ROVE LILIANA L JOHNSON LESTER W | 2006 | International Journal of Researeh in Marketing2006，23，1： | 1 |
| 6 | Muskmelon fruit soluble acid invertase and sucrose phosphate synthase activity and polypeptide profiles during growth and maturation显示文摘 | LESTER G E ARIAS L S L LIM M G | 2001 | J Amer Soc Hort Sci2001，126，： | 1 |
| 7 | Acceleration ofpolyacrylamide photopolymerization using lyotropic liquid crystaltemplates显示文摘 | LESTER C L SMITH S M GUYMON C A | 2001 | Macromolecules2001，34，： | 1 |
| 8 | A recent history of metal accumulation in the sediments of the Thames Estuary,United Kingdom显示文摘 | Wiese S B O Macleod C L Lester J N | 1997 | Estuaries1997，20，3： | 1 |
| 9 | A recent history of metal accu- mulation in the sediments of the Thames Estuary,United Kingdom 显示文摘 | Wiese S B O Macleod C L Lester J N | 1997 | Estuaries1997，20，3： | 1 |
| 10 | Developing a selective breeding plan for penaeid shrimp mariculture 显示文摘 | Lester L J | 1983 | Aquaculture1983，33，： | 1 |
| 11 | From generic restoration to specific restoration strategies显示文摘 | LESTER H F LION K L LIU C C | | 0，，2： | 1 |
| 12 | The sphingoid long chain base phytosphingosine activates AGC- type protein kinases in Saccharomyces cerevisiae in- cluding Ypkl, Ypk2, and Sch9 显示文摘 | Liu K Zhang X Lester R L | 2005 | J Biol Chem2005，280，22： | 1 |
| 13 | Supplement foliarpotassium applications during muskmelon fruit developmentcan improve fruit quality,ascorbic acid,and beta-carotenecontents显示文摘 | LESTER G E JIFON J L ROGERS G | 2005 | J Am Soc Horti Sci2005，130，4： | 1 |
| 14 | Sugars in developing and mature fruits of several watermelon cμLtivars显示文摘 | Lester Paul L D | 1981 | J Amer Soe Hort Sci1981，106，3： | 1 |
| 15 | Determination of endocrine disrupters in sewage treatment and receiving waters显示文摘 | Rachel L Gomes Mark D Scrimshaw John N Lester | 2003 | Trends in Analytical Chemistry2003，22，10： | 1 |
| 16 | A recent history of metal accumulation in the sdiments of the Thames Estuary, United Kingdom显示文摘 | Wiese S B O Macleod C L Lester J N | 1997 | Estuaries1997，20，3： | 1 |
| 17 | Muskmelon fruit soluble acid invertase and sucrose phosphate synthase activity and polypeptide profiles during growth and maturation显示文摘 | LESTER G E ARIAS L S LIM M G | 2001 | J Amer Soc Hort Sci2001，126，2： | 1 |
| 18 | Sphingolipids with inositolphosphate-containing head groups显示文摘 | Lester R L Dickson R C | 1993 | Adv Lipid Res1993，26，： | 1 |
| 19 | Development of a patient experience questionnaire for primary care mental health 显示文摘 | Mavaddat N Lester HE Tait L | 2009 | Qual Saf Health Care2009，18，2： | 1 |
| 20 | Habitat complexity facilitates eo- existenee in a tropical ant community 显示文摘 | Sarty M Abbott K L Lester P J | 2006 | Oeeologia2006，149，3： | 1 |
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