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| 1 | Efficacy and safety of FIREHAWK abluminal groove filled biodegradable polymer sirolimus-eluting stents for the treatment of long coronary lesions: nine-month angiographic and one-year clinical results from TARGET I trial lona cohort显示文摘 | XU Bo GAO Run-lin ZHANG Rui-yan WANG Hai-chang LI Zhan-quan YANG Yue-jin MA Chang-sheng HAN Ya-ling Alexandra J. Lansky HUO Yong LI Wei Martin B. Leon | 2013 | Chinese Medical Journal2013，，6： | 8 |
| 2 | Meta-analysis of the effects of 1-methylcyclopropene(1-MCP)treatment on climacteric fruit ripening显示文摘1-Methylcyclopropene(1-MCP)is an inhibitor of ethylene perception that is widely used to maintain the quality of several climacteric fruits during storage.A large body of literature now exists on the effects of 1-MCP on climacteric fruit ripening for different species and environmental conditions,presenting an opportunity to use meta-analysis to systematically dissect these effects.We classified 44 ripening indicators of climacteric fruits into five categories:physiology and biochemistry,quality,enzyme activity,color,and volatiles.Meta-analysis showed that 1-MCP treatment reduced 20 of the 44 indicators by a minimum of 22%and increased 6 indicators by at least 20%.These effects were associated with positive effects on delaying ripening and maintaining quality.Of the seven moderating variables,species,1-MCP concentration,storage temperature and time had substantial impacts on the responses of fruit to 1-MCP treatment.Fruits from different species varied in their responses to 1-MCP,with the most pronounced responses observed in rosaceous fruits,especially apple,European pear fruits,and tropical fruits.The effect of gaseous 1-MCP was optimal at 1μl/l,with a treatment time of 12–24 h,when the storage temperature was 0℃for temperate fruits or 20℃for tropical fruits,and when the shelf temperature was 20℃,reflecting the majority of experimental approaches.These findings will help improve the efficacy of 1-MCP application during the storage of climacteric fruits,reduce fruit quality losses and increase commercial value. | Jing Zhang Yuanchun Ma Chao Dong Leon A.Terry Christopher B.Watkins Zhifang Yu Zong-Ming(Max)Cheng | 2020 | Horticulture Research2020，7，1： | 7 |
| 3 | Cloning and DNA sequence of plasmid determinant iss, coding for increased serum survival and surface exclusion, which has homology with lambda DNA显示文摘 | Chuba PJ Leon MA Banerjee A | 1989 | Mol Gen Genet1989，216，23： | 1 |
| 4 | Risk factors for abdomnal scar endometrosis after obstetric hysterotomies acase controlstudy 显示文摘 | de OIiveira MA de Leon AC Freire EC | 2007 | Acta Obstet GynecolScand2007，86，1： | 1 |
| 5 | Tau oligomers and aggregation in Alzheimer' s disease 显示文摘 | Meraz-Rios MA Lira-De Leon KI Campos-Pena V | 2010 | J Neurochem2010，112，6： | 1 |
| 6 | Preliminary evidence ofan adolescent HIV/AIDS peer education program显示文摘 | Mahat G Scoloveno MA De Leon T | 2008 | J PediatrNurs2008，23，5： | 1 |
| 7 | Chronic cerebrospinal venous insufficiency is not associated with multiple sclerosis and its severity:a blind-veri- fied study 显示文摘 | Leone MA Raymkulova O Naldi P | 2013 | PLoSOne2013，8，56： | 1 |
| 8 | Early diagnosis of candidiasis in non-neutropenic critically ill patients显示文摘 | Nolla-Salas M Leon MA | 2004 | J Infect2004，48，2： | 1 |
| 9 | Hydrogen peroxide stimulates salicylic acid biosynthesis in tobacco显示文摘 | Leon J Lawton MA Raskin I | 1995 | Plant Physiol1995，，108： | 1 |
| 10 | Effect of neuromuscular blockade on the elastic properties of the lungs, thorax, and total respiratory system in anesthetized pigs 显示文摘 | Putenseu C Leon MA Putensen-Himmer G | 1994 | Crit Care Med1994，22，12： | 1 |
| 11 | Hydrogen peroxide stimulates salicylic acid biosynthesis in tobacco 显示文摘 | LEON J LAWTON MA RASKIN I | 1995 | Plant Physiol1995，108，： | 1 |
| 12 | Effects of corticosteroids in very low birth weight newborns dependent on mechanical ventilation显示文摘 | Mataloun MM Leone CR Gibelli MA | 2005 | Clinics2005，60，2： | 1 |
| 13 | Serum caffeine concentrations in preterm neonates显示文摘 | LEON A E MICHIENZI K MA C X | 2007 | Am J Perinatol2007，24，1： | 1 |
| 14 | Mycobacterium tuberculosis ESAT-6 exhibits aunique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis显示文摘 | De Leon J Jiang G Ma Y | 2012 | J Biol Chem2012，287，44： | 1 |
| 15 | STAT3 and AKT signaling pathways mediate oncogenic role of NRSF in hepatocellular carcinoma显示文摘Neuron-restrictive silencer factor(NRSF)is a zinc finger protein that acts as a negative transcriptional regulator by recruiting histone deacetylases and other co-factors.It plays a crucial role in nervous system development and is recently reported to be involved in tumorigenesis in a tumor type-dependent manner;however,the role of NRSF in hepatocellular carcinoma(HCC)tumorigenesis remains unclear.Here,we found that NRSF expression was up-regulated in 27 of 49 human HCC tissue samples examined.Additionally,mice with conditional NRSF-knockout in the liver exhibited a higher tolerance against diethylnitrosamine(DEN)-induced acute liver injury and were less sensitive to DEN-induced HCC initiation.Our results showed that silencing NRSF in HepG2 cells using RNAi technology significantly inhibited HepG2 cell proliferation and severely hindered their migration and invasion potentials.Our results demonstrated that NRSF plays a pivotal role in promoting DEN-induced HCC initiation via a mechanism related to the STAT3 and AKT signaling pathways.Thus,NRSF could be a potential therapeutic target for treating human HCC. | Ming Ma Yunhe Zhou Ruilin Sun Jiahao Shi Yutong Tan Hua Yang Mengjie Zhang Ruling Shen Leon Xu Zhugang Wang Jian Fei | 2020 | Acta Biochimica et Biophysica Sinica2020，52，10： | 1 |
| 16 | Non-polymer-based paclitaxel-coated coronary stents for the treatment of patients with de novo coronary lesions: angiographic follow-up of the DELIVER clinical trial显示文摘 | Lansky AJ Costa RA Mintz GS Tsuchiya Y Midei M Cox DA O'Shaughnessy C Applegate RA Cannon LA Mooney M Farah A Tannenbaum MA Yakubov S Kereiakes DJ Wong SC Kaplan B Cristea E Stone GW Leon MB Knopf WD O'Neill WW DELIVER Clinical Trial Investigators | 2004 | Circulation2004，109，16： | 1 |
| 17 | The origin of the spinal subdural space: ultrastructure findings显示文摘 | Reina MA De Leon Casasola O López A | 2002 | Anesth Analg2002，94，4： | 1 |
| 18 | The origin of the spinal subdural space : ultrasiruclurefindings 显示文摘 | Reina MA de Leon Casasola O Lopez A | 2002 | Anesth Analg2002，94，4： | 1 |
| 19 | Nodular myofibroblastic stromal hyperplasia of the mammary gland as an accurate name for pseudoangiomatous stromal hyperplasia of the mammary gland显示文摘 | Leon ME Leon MA Ahuja J | 2002 | Breast J2002，8，5： | 1 |
| 20 | Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomy显示文摘 | Zhou YF Leon MB Waclawiw MA | 1996 | N Engl J Med1996，335，： | 1 |
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