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147篇 您的检索式：作者名="Lens A"

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	题名	作者	年代	出处	被引量
1	临床上有显著门静脉高压症的患者口服抗HCV药物治疗后的血流动力学变化及临床结果显示文摘【据Journal of Hepatology 2020年5月报道】题:临床上有显著门静脉高压症的患者口服抗HCV药物治疗后的血流动力学变化及临床结果(作者Lens S等)在使用直接抗病毒药物治疗的丙型肝炎肝硬化患者中,有显著临床意义的门静脉高压症(CSPH,HVPG≥10 mm Hg)在持续病毒学应答(SVR)24周后持续存在。这些患者仍有失代偿的风险。然而,长期配对的临床和血流动力学数据不适用于该人群。	武彤辛桂杰 LENS S BAIGES A ALVARADO E	2020	临床肝胆病杂志2020，36，9：	8
2	Aplastic anemia and severe pancytopenia during treatment with peg-interferon,ribavirin and telaprevir for chronic hepatitis C显示文摘Telaprevir and Boceprevir are the first direct acting antivirals approved for chronic hepatitis C in combination with peg-interferon alfa and ribavirin.Pancytopenia due to myelotoxicity caused by these drugs may occur,but severe hematological abnormalities or aplastic anemia(AA) have not been described.We collected all cases of severe pancytopenia observed during triple therapy with telaprevir in four Spanish centers since approval of the drug in 2011.Among 142 cirrhotic patients receiving treatment,7 cases of severe pancytopenia(5%) were identified and three were consistent with the diagnosis of AA.Mean age was 59 years,five patients had compensated cirrhosis and two patients had severe hepatitis C recurrence after liver transplantation.Severe pancytopenia was diagnosed a median of 10 wk after the initiation of therapy.Three patients had pre-treatment hematological abnormalities related to splenomegaly.In six patients,antiviral treatment was interrupted at the onset of hematological abnormalities.Two patients died due to septic complications and one patient due to acute alveolar hemorrhage.The remaining patients recovered.Severe pancytopenia and especially AA,are not rare during triple therapy with telaprevir in patients with advanced liver disease.Close monitoring is imperative in this setting to promptly detect serious hematological disorders and to prevent further complications.	Sabela Lens Jose L Calleja Ana Campillo Jose A Carrion Teresa Broquetas Christie Perello Juan de la Revilla Zoe Marino Maria-Carlota Londono Jose M Sanchez-Tapias Alvaro Urbano-Ispizua Xavier Forns	2015	World Journal of Gastroenterology2015，21，17：	4
3	Anti-CTLA4 monoclonal antibody Ipilimumab in the treatment of metastatic melanoma:recent findings显示文摘	Lens M Ferrucci PF Testori A		0，，2：	1
4	An efficient integration of algorithms to evaluate the quality of free form surfaces显示文摘	Lennings A F Peters J G Vergeest J S M	1995	Computer & Graphics1995，19，6：	1
5	Quantitative flow cytometry can distinguish betweennormal and leukaemic B-cell precursors 显示文摘	FarahatN Lens D Zomas A	1995	BrJ Haematol1995，91，：	1
6	Coating of anionic surfactants onto poly(ethylene)surfaces studied with X-ray photoelection spectroscopy显示文摘	Lens J P Terlingen J A	1998	Langmuir1998，14，12：	1
7	Long-term competition between sulfate reducing and methanogenic bacteria in uasb reactors treating volatile fatty acids显示文摘	Lens P Visser A	1998	Biotechnology and Bioengineering1998，57，6：	1
8	Direct and indirect effects: Classical and bootstrap estimates of variability 显示文摘	BOI LEN K A STINE R	1990	Sociological Methodology1990，20，1：	1
9	Prevalence of malnutrition in a mid-long term stay unit显示文摘	Argente Pla M Garc侏a Malpartida K Len De Zayas B	2014	NutrHosp2014，31，2：	1
10	Cluster structure of anaerobic aggregates of an expanded granular sludge bed reactor显示文摘	Gonzalez-Gil G Lens P N L Aelst A	2001	Applied and Environmental Microbiology2001，67，：	1
11	Notes on hydrated cement fractals investigated by SANS显示文摘	Ficker T Len A Nemecp	2007	Journal of Physics D Applied Physics2007，40，13：	1
12	Valgancielovir as pre- emptive therapy for cytomegalovims infection in allogeneic haemato- poietie stem cell transplant recipients 显示文摘	Ruiz-Camps I Len O de la Cdmm'a R	2011	Antivir Ther2011，16，7：	1
13	The anti-apoptotic factor Bcl-2can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF显示文摘	Tardivel A Tinel A Lens S	2004	Eur J immunol2004，34，2：	1
14	Performance of a sulfide-oxidizing expanded-bed reactor supplied with dis- solved oxygen 显示文摘	Janssen A J H Ma S C Lens P	1997	Biotechnol Bioeng1997，53，1：	1
15	Frequency-scalSuable SiGe bipolar RF front-end design 显示文摘	Osama Shana ' a Ivan Linscott Len Tyler	2001	IEEE J Solid-State Circuits2001，36，6：	1
16	Perform- ance of a sulfide - oxidizing expanded - bed reactor sup- plied with dissolved oxygen显示文摘	Janssen A J H Ma S N Lens P Lettinga G	1997	Biotechnol Bioeng1997，53，01：	1
17	Efficacy of two meth- ods for red ueing postbypass afterdrop显示文摘	Rajek A Len hard t R Sess let DI etal	2000	Anesthesiology2000，92，2：	1
18	Pharnmeokinetic model selectionfor target controlled assessment of three parameter sets显示文摘	Coetzee J F Len J B Wium C A	1995	Anesthesiology1995，82，6：	1
19	Biotechnological treatment of sulfate-rich wastewaters 显示文摘	Lens P N L Visser A Janssen A J H	1998	Critical Reviews in Environmental Science and Technology1998，28，1：	1
20	Anti - CTLA4 monoclonal anti- body Ipilimumab in the treatment of metastatic melanoma: recent findings显示文摘	Lens M Ferrucci PF Testori A	2008	Recent Pat Antieancer Drug Discov2008，3，2：	1

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