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| 1 | Opportunistic screening for atrial fibrillation with a single lead device in geriatric patients显示文摘Objective To determine the diagnostic yield of repeated screening for atrial fibrillation(AF)among geriatric patients.Methods A pragmatic prospective cohort study into applying opportunistic screening for AF with a handheld single lead ECG device(SLD)in a geriatric cohort.Consecutive patients of 65 years old and older visiting the geriatric outpatient clinic were eligible for inclusion.A 12 lead ECG was performed,followed by measurements with the SLD during every visit to the geriatric outpatient clinic.A frailty index was based on the accumulation of deficits model.Results 478 patients were eligible.Patients were excluded if they did not give informed consent(17 patients),had a pacemaker or implantable cardioverter defibrillator(20 patients),or had incomplete medical files(two patients).After exclusion,439 patients participated in this study.The mean age was 78 years(range 65 to 100 years),54%were female.AF was known in 89 patients(20%),first detected on the baseline ECG in four patients(1%)and first detected with the SLD in 20 patients(5%)during follow up visits.Sensitivity of the SLD was 90.0%,specificity 99.0%,negative predictive value 99.7%,and positive predictive value 73.5%.Most patients(82%)with AF were frail and 53%were severely frail.Conclusion Repeated screening in geriatric patients has a five times higher diagnostic yield than usual care.It was easily combined with usual care.Because of the positive predictive value of 73.5%,it remains necessary to confirm AF with a 12 lead ECG or 24-h Holter monitoring. | Lennaert AR Zwart Rene WMM Jansen Jacob H Ruiter Tjeerd Germans Suat Simsek Martin EW Hemels | 2020 | Journal of Geriatric Cardiology2020，17，3： | 1 |
| 2 | Short-term vitamin D3 supplementation lowers plasma renin activity in patients with stable chronic heart failure: An open-label, blinded end point, randomized prospective trial (VitD-CHF trial)显示文摘 | Nicolas F. Schroten Willem P.T. Ruifrok Lennaert Kleijn Martin M. Dokter Herman H. Silljé Hiddo J. Lambers Heerspink Stephan J.L. Bakker Ido P. Kema Wiek H. van Gilst Dirk J. van Veldhuisen Hans L. Hillege Rudolf A. de Boer | 2013 | American Heart Journal2013，，2： | 1 |
| 3 | LONG-TERM RIGOROUS NUMERICAL INTEGRATION OF NAVIER-STOKES EQUATION BY NEWTON-GMRES ITERATION显示文摘The recent result of an orbit continuation algorithm has provided a rigorous method for long-term numerical integration of an orbit on the unstable manifold of a periodic solution.This algorithm is matrix-free and employs a combination of the Newton-Raphson method and the Krylov subspace method.Moreover,the algorithm adopts a multiple shooting method to address the problem of orbital instability due to long-term numerical integration.The algorithm is described through computing the extension of unstable manifold of a recomputed Nagata′s lowerbranch steady solution of plane Couette flow,which is an example of an exact coherent state that has recently been studied in subcritical transition to turbulence. | Julius Rhoan T.Lustro Lennaert van Veen Genta Kawahara | 2013 | Transactions of Nanjing University of Aeronautics and Astronautics2013，30，3： | 0 |
| 4 | 瓦赫宁根大学研究中心Orion大楼显示文摘0rion大楼是瓦赫宁根大学研究中心的第二栋中央学术大楼。这是一栋具有极高灵活性和效率性的大楼.用以应对该大学未来不断增长的空间需求。像一般的学术大楼一样.这座大楼内部设计有食堂、演讲厅.指令区和实验室。建筑师对不同空间类型的分布进行了合理的安排:最繁忙的空间——如咖啡厅、饭店、演讲厅——都尽可能地设在一层.而那些需要高度依赖科技设备的空间——如实验室等——尽量设在大楼的顶层,直接位于设备安装区域下面。 | Joost Ector Max Pape Stijn Rademakers Lennaert van Capelleveen Sander Visscher Lesley Bijholt Nejra Vaizovic Rena Logara Joost van der Linden Arja Hoogstad Sabine Alders Luca Sandri Maarten van Nierop Damion Schwarzkachel | 2012 | 中国建筑装饰装修2012，，11： | 0 |
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