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| 1 | Nationwide trends and predictors of inpatient mortality in 83884 transjugular intrahepatic portosystemic shunt显示文摘AIM: To evaluate and validate the national trends and predictors of in-patient mortality of transjugular intrahepatic portosystemic shunt(TIPS) in 15 years.METHODS: Using the National Inpatient Sample which is a part of Health Cost and Utilization Project, we identified a discharge-weighted national estimate of 83884 TIPS procedures performed in the United States from 1998 to 2012 using international classification of diseases-9 procedural code 39.1. The demographic, hospital and co-morbility data were analyzed using a multivariant analysis. Using multi-nominal logistic regression analysis, we determined predictive factors related to increases in-hospital mortality. Comorbidity measures are in accordance to the Comorbidity Software designed by the Agency for Healthcare Research and Quality.RESULTS: Overall, 12.3% of patients died during hospitalization with downward trend in-hospitalmortality with the mean length of stay of 10.8 ± 13.1 d. Notable, African American patients(OR = 1.809 vs Caucasian patients, P < 0.001), transferred patients(OR = 1.347 vs non-transferred, P < 0.001), emergency admissions(OR = 3.032 vs elective cases, P < 0.001), patients in the Northeast region(OR = 1.449 vs West, P < 0.001) had significantly higher odds of inhospital mortality. Number of diagnoses and number of procedures showed positive correlations with in-hospital death(OR = 1.249 per one increase in number of procedures). Patients diagnosed with acute respiratory failure(OR = 8.246), acute kidney failure(OR = 4.359), hepatic encephalopathy(OR = 2.217) and esophageal variceal bleeding(OR = 2.187) were at considerably higher odds of in-hospital death compared with ascites(OR = 0.136, P < 0.001). Comorbidity measures with the highest odds of in-hospital death were fluid and electrolyte disorders(OR = 2.823), coagulopathy(OR = 2.016), and lymphoma(OR = 1.842).CONCLUSION: The overall mortality of the TIPS procedure is steadily decreasing, though the length of stay has remained relatively constant. Specific patient ethnicity, location, transfer status, primary diagnosis and comorbidities correlate with increased odds of TIPS in-hospital death. | Edward Wolfgang Lee Andrew Kuei Sammy Saab Ronald W Busuttil Francisco Durazo Steven-Huy Han Mohamed M El-Kabany Justin P Mc Williams Stephen T Kee | 2016 | World Journal of Gastroenterology2016，22，25： | 7 |
| 2 | 急性缺血性脑卒中后低脉压与不良预后相关显示文摘众所周知,脉压与心脏功能、动脉僵硬度、体液状态和血管事件有关。该研究旨在探讨基于中国台湾地区脑卒中登记资料的急性缺血性脑卒中(acute ischemic stroke,AIS)患者入院时脉压的预后作用。 | 刘莉 叶鹏 Tang SC Yin JH Liu CH Sun MH Lee JT Sun Y Hsu CS Sun MC Lin CH Chen CH Lien LM Muo CH Jeng JS Hsu CY | 2017 | 中华高血压杂志2017，25，7： | 5 |
| 3 | 前额叶损伤患者的风险决策认知障碍显示文摘目的探讨前额叶眶部(OBF)和背外侧(DLF)损伤对风险决策认知加工的影响,验证OBF参与风险决策认知加工过程的假说。方法OBF损伤患者21例,DLF损伤患者19例以及健康对照组(HC)40名,采用风险决策任务,比较各组执行风险决策的能力。结果组内与奖赏后相比,惩罚后HC组的风险选择频率显著下降(分别为0.68±0.16和0.54±0.23,P<0.01),表现为惩罚后风险选择的抑制效应;DLF损伤组患者在惩罚后的风险选择频率亦有显著下降(分别为0.72±0.22和0.63±0.25,P<0.05);而OBF损伤组患者在惩罚后风险选择的抑制效应消失(分别为0.79±0.19和0.82±0.18,P>0.05)。与HC组比较,OBF损伤组患者在奖赏后和惩罚后的风险选择频率均显著升高(奖赏后分别为0.68±0.16和0.79±0.19,惩罚后分别为0.54±0.23和0.82±0.18;P<0.05),而DLF损伤组患者无显著变化(奖赏后分别为0.68±0.16和0.72±0.22,惩罚后分别为0.54±0.23和0.63±0.25;P>0.05)。结论OBF和DLF在人类的风险决策认知加工过程存在分离。OBF损伤后的患者追求高奖赏,惩罚后风险选择的抑制效应消失,而DLF损伤组患者的风险决策能力正常。OBF可能参与了奖赏/惩罚认知加工过程,是风险决策认知加工和处理的重要脑区。 | 席春华 傅先明 汪凯 牛朝诗 Lee Tatia MC 孟玉 朱春燕 杜静 | 2006 | 中华医学杂志2006，86，45： | 3 |
| 4 | Roles of paroxetine and corticosterone on adult mammalian ciliary body cell proliferation显示文摘背景在成年哺乳动物的视网膜的神经发生通常被废除,并且这显示再生 capacity.Despite 的视网膜缺乏这,有在保留学习在调查二药,皮质脂酮和 paroxetine 的效果瞄准了的在场的神经原的 potential.The 的睫的上皮的nestin积极的房间的一张小人口,在老鼠是的睫的 body.Methods 成年人 Sprague-Dawley 的房间增长上给车辆,皮质脂酮, paroxetine ,或两个 | WANG Hua LAU Benson WM YAU Suk-yu LI Suk-yee LEUNG Nelson WANG Ning-li TANG Siu-wa LEE Tatia MC SO Kwok-fai | 2010 | Chinese Medical Journal2010，，10： | 2 |
| 5 | 有症状无功能的胰腺神经内分泌肿瘤并发不可切除的肝转移病人有手术指征吗显示文摘对进展期胰腺神经内分泌肿瘤,即使存在不可切除的肝转移,依然可以存活数年,而非数月。理论上,我们应该姑息性切除这类病人有症状的原发性神经内分泌肿瘤,然而,切除伴肝转移病人的原发胰腺肿瘤的效果和可行性鲜有报道。2000年起,作者对病理证实的胰腺内分泌肿瘤伴发肝转移病人进行前瞻性研究,对原发胰腺肿瘤进行切除,肝转移病灶行肝动脉栓塞化疗。结果13例病人进行了上述治疗,其中7例行胰十二指肠切除术,6例行胰尾切除并脾脏切除术,无术中死亡,胰腺肿瘤大小平均8cm(3-19cm)。 | Hung JS Chang MC Lee PH | 2009 | 中华肝胆外科杂志2009，15，4： | 2 |
| 6 | A prospective feasibility study of sub-millisievert abdominopelvic CT using iterative reconstruction in Crohn’s disease显示文摘 | Siobhan B O’Neill Patrick D Mc Laughlin Lee Crush Owen J O’Connor Sebastian R Mc Williams Orla Craig Anne Marie Mc Garrigle Fiona O’Neill Jackie Bye Max F. Ryan Fergus Shanahan Michael M Maher | 2013 | European Radiology2013，，： | 2 |
| 7 | c - JUN expression and apoptotic cell death in kainite- induced temporal lobe epilepsy显示文摘 | Rho JL Woo YJ | 2001 | J Korean Med Sci2001，16，5： | 1 |
| 8 | Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcino -ma显示文摘 | Lee HZ Hsu SL Liu MC | 2001 | Eur J Pharmacology2001，431，3： | 1 |
| 9 | Maternal influences on adult blood pressure of SHR: a singlepup cross-fostering study显示文摘 | MC Carty R Lee JH | 1996 | Physiol Behav1996，59，： | 1 |
| 10 | Laparoscopic nephroureterctomy with bladder-cuff resection techniques and outcomes显示文摘 | Tan BJ Ost MC Lee BE | 2005 | Endourol2005，19，6： | 1 |
| 11 | Cognitive effects of hormone therapy in men with prostate cancer:a review显示文摘 | Nelson CJ Lee JS Gamboa MC | 2008 | Cancer2008，113，： | 1 |
| 12 | Tuberculosis susceptibility of diabetic mice 显示文摘 | Martens GW Arikan MC Lee J | 2007 | Am J Respir Cell Mol Biol2007，37，5： | 1 |
| 13 | Adenosquamous/squamous cell carcinoma of the gallbladder 显示文摘 | Chan KM Yu MC Lee WC | 2007 | J Surg Oncol2007，95，2： | 1 |
| 14 | Retroperitoneal liposar- comas: the experience of a tertiary Asian center显示文摘 | Lee SY Goh BK Teo MC | 2011 | World J Surg Oneol2011，9，： | 1 |
| 15 | Hilar cholangiocarcinoma: Comparative study with sonography, and CT显示文摘 | Choi BL Lee JH Han MC | 1989 | Radiology1989，172，： | 1 |
| 16 | calcium/calmodulin kinase Ⅱ activity of hippocampus in kainite-induced epilepsy显示文摘 | Lee MC Ban SS Woo YJ | 2001 | J Korean Med Sci2001，16，： | 1 |
| 17 | Caspase-3-dependent apoptosis in vascularsmooth muscle cell by proteasome inhibition显示文摘 | Kim SC Rho MC Lee HS | 2003 | J Cardiol Pharmol2003，42，4： | 1 |
| 18 | Giant colonic lipomaas lead point for intermittent colo-colonic intussusception 显示文摘 | ROGERS SOJR LEE MC ASHLEY SW | 2002 | Surgery2002，131，： | 1 |
| 19 | Bi-directional protein transport between the ER and Golgi显示文摘 | Lee MC Miller EA Goldberg J | 2004 | Annu Rev Cell Dev Biol2004，20，： | 1 |
| 20 | A creep apparatus to explore the quenching and aging phenomena of PVC films显示文摘 | Lee H H D Mc Garry F J | 1991 | Journal of Materials Science1991，26，1： | 1 |
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