|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 面向21世纪的卒中新定义:美国心脏病学会和美国卒中学会声明显示文摘尽管脑血管病有着全球性影响且对其病理生理学的认识有了很多进步,但是'卒中'这一术语在临床实践、临床研究或公共卫生评估中的定义却不一致。传统的定义依据于临床,却没有考虑到科学技术的进步。美国心脏协会(AHA)和美国卒中协会(ASA)卒中分会组织了写作小组,为21世纪卒中新定义撰写专家共识性声明。中枢神经系统(CNS)梗死,指由缺血所导致的脑、脊髓或视网膜的细胞死亡,是基于持续性损害的神经病理学、神经影像学和(或)临床证据。CNS梗死表现为一个临床谱:缺血性卒中特指伴有明显症状的CNS梗死,而静息性梗死根据定义指未引起已知的症状的梗死。卒中也还包括脑出血和蛛网膜下腔出血。新定义的卒中结合了临床和组织学标准,可被用于实践、研究和公共卫生评估。 | 俞羚 董荃 宋叶平 江静雯 李卉 刘亮贤 苏爱萍 李焰生 Sacco RL Kasner SE Broderick JP Caplan LR Connors JJ Culebras A Elkind MS George MG Hamdan AD Higashida RT Hoh BL Janis LS Kase CS Kleindorfer DO Lee JM Moseley ME Peterson ED Turan TN Valderrama AL Vinters HV | 2013 | 神经病学与神经康复学杂志2013，10，2： | 188 |
| 2 | Risk factors and natural history of breast cancer in younger Chinese women显示文摘AIM: To investigate the age differences in the risk factors, clinicopathological characteristics and patterns of treatment of female breast cancer patients. METHODS: Seven thousand one hundred and fiftytwo women with primary breast cancer from the Hong Kong Breast Cancer Registry were recruited after receiving patients' consent, they were asked to complete standardized questionnaires which captured their sociodemographic characteristics and risk factors associated with breast cancer development. Among them, clinicopathological data and patterns of treatment were further collected from medical records of 5523 patients with invasive breast cancers. Patients were divided into two groups according to the age at diagnosis: younger(< 40 years old) vs older patients(≥ 40 years old) for subsequent analyses.RESULTS: Analysis on the sociodemographic characteristics and exposure to risk factors were performed on 7152 women with primary breast cancer and the results revealed that younger patients were more likely to have unhealthy lifestyles; these include a lack of exercise(85.4% vs 73.2%, P < 0.001), having high stress in life(46.1% vs 35.5%, P < 0.001), having dairy/meat-rich diets(20.2% vs 12.9%, P < 0.001),having alcohol drinking habit(7.7% vs 5.2%, P = 0.002). Younger patients were also more likely to have hormone-related risk factors including nulliparity(43.3% vs 17.8%, P < 0.001) and an early age at menarche(20.7% vs 13.2%, P < 0.001). Analyses on clinicopathological characteristics and patterns of treatment were performed on 5523 women diagnosed with invasive breast cancer. The invasive tumours in younger patients showed more aggressive pathological features such as having a higher percentage of grade 3 histology(45.7% vs 36.5%, P < 0.001), having a higher proportion of tumours with lymphovascular invasion(39.6% vs 33.2%, P = 0.003), and having multifocal disease(15.7% vs 10.3%, P < 0.001); they received different patterns of treatment than their older counterparts.CONCLUSION: Younger patients in Hong Kong are more likely to encounter risk factors associated with breast cancer development and have more aggressive tumours than their older counterparts. | Winnie Yeo Hang-Mei Lee Amy Chan Emily YY Chan Miranda CM Chan Keeng-Wai Chan Sharon WW Chan Foon-Yiu Cheung Polly SY Cheung Peter HK Choi Josette SY Chor William WL Foo Wing-Hong Kwan Stephen CK Law Lawrence PK Li Janice WH Tsang Yuk Tung Lorna LS Wong Ting-Ting Wong Chun-Chung Yau Tsz-Kok Yau Benny CY Zee | 2014 | World Journal of Clinical Oncology2014，5，5： | 4 |
| 3 | AFLP markers distinguish an early mutant of Flameseedless grape显示文摘 | Scott KD Ablett EM Lee LS | 2000 | Euphytica2000，113，： | 1 |
| 4 | Appearance and aflatoxin contents of raw and dry roasted peanut kennels显示文摘 | Lee LS Cucullu AF Goldblatt LA | 1968 | Food Technol1968，22，： | 1 |
| 5 | Identification of a minimal domain of 5 S ribosomal' RNA sufficient for high affinity interactions with the RNA-specific zinc fingers of transcription factor ⅢA显示文摘 | Neely LS Lee BM Xu J | 1999 | J Mol Biol1999，291，： | 1 |
| 6 | A prospective study to compare the diagnostic performance of breast elastography versus conventional breast ultrasound 显示文摘 | Leong LC Sire LS Lee YS | 2010 | Clin Radiol2010，65，11： | 1 |
| 7 | Placental expression of DC-SIGN may mediate intrauterine vertical transmission of HIV 显示文摘 | Soilleux EJ Morris LS Lee B | 2001 | J Pathol2001，195，5： | 1 |
| 8 | Cytology from pancreatic cysts has marginal utility in surgical decision-making 显示文摘 | Maker AV Lee LS Rant CP | 2008 | Ann Surg Oncol2008，15，11： | 1 |
| 9 | Efficacy and safety of diphenylcyclopropenone among Chinese patients with steroid resistant and extensive alopecia areata显示文摘 | Luk NM Chiu LS Lee KC | 2013 | J Eur Acad Dermatol Venereol2013，27，3： | 1 |
| 10 | Increased muscular challenge in older adults during obstructed gait显示文摘 | Hahn ME Lee HJ Chou LS | 2005 | Gait Posture2005，22，4： | 1 |
| 11 | EUS-guided fine needle aspiration of pancreatic cysts: a retrospective analysis of complica- tions and their predictors 显示文摘 | Lee LS Saltzman JR Bounds BC | 2005 | Clin Gastroenterol Hepatol2005，3，3： | 1 |
| 12 | Antigenic diversity of Neisse- ria meningitidis isolated in Taiwan between 1995 and 2002 显示文摘 | Yang CY Lee YS Huang LS | 2006 | Scand J Infect Dis2006，38，4： | 1 |
| 13 | Cytology from pancreatic cysts has marginal utility in surgical decision-making 显示文摘 | Maker AV Lee LS Raut CP | 2008 | Ann Surg Oncol2008，15，11： | 1 |
| 14 | Central nervous infection in patients with systemic lupus erythematosus显示文摘 | Hung JJ Ou LS Lee WJ | 2005 | J Rheumatol2005，32，1： | 1 |
| 15 | Hypolipidemie and antioxidant properties of phenolic compound-rich extracts from white ginseng (Panax ginseng) in cholesterol-fed rabbits 显示文摘 | Lee LS Won CW Hong HD | 2013 | Molecules2013，18，12： | 1 |
| 16 | A prospective study to compare the diagnostic performance of breast elastography versus conventional breast ultrasound显示文摘 | Leong LC Sim LS Lee YS | | 0，，11： | 1 |
| 17 | The frequency of amniotic fluid increases as a function of the duration of labor 显示文摘 | Lee KA Mi LS Jin YH | 2011 | The Journal of Maternal-Fetal & Neonatal Medicine2011，24，7： | 1 |
| 18 | Phosphatidylinositol 3'-kinase activation leads to multidrug resistance protein-1 expression and subsequent chemoresistance in advanced prostate cancer cells 显示文摘 | Lee JT Jr Steelman LS MeCubrey JA | 2004 | Cancer Res2004，64，22： | 1 |
| 19 | Mass spectrometric analysis of tumor necrosis factor receptorassociated factor 1 ubiquitination mediated by cellular inhibitor of apoptosis 显示文摘 | Lee LS Hong US Lee TH | 2004 | Proteomics2004，4，11： | 1 |
| 20 | A muhicenter noncomparative clinical study on midface rejuvenation using a nonabsorbable poly- propylene mesh : evaluation of efficacy and safety 显示文摘 | Pak CS Chang LS Lee H | 2015 | Arch Plast Surg2015，42，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员