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17篇 您的检索式:作者名="Ledwaba"
    题名 作者 年代 出处 被引量
1Molecular genetics of human cervical cancer:role of papillomavirus and the apoptotic cascade显示文摘LEDWABA T DLAMINI Z MAICKER S 2004Biol Chem2004,385,8:1
2Viremia and drug resistance among HIV-1 patients on antiretroviral treatment: a cross-sectional study in Soweto,South Africa显示文摘El-Khatib Z Ekstrom AM Ledwaba J 0,,:1
3Effectiveness of 25-hydroxycholecalciferol in the prevention of tibial dyschondroplasia in Ross cockerels depends on dietary calcium level显示文摘Ledwaba M F Roborson K D 2003Poultry Sci2003,82,:1
4Molecular genetics of human cervical cancer:role of papillomavirus and the apoptotic cascade显示文摘Ledwaba T Dlamini Z Naicker S 2004Biol Chem2004,385,8:1
5Molecular genetics of human cervical cancer:role of papillomavirus and the apoptotic cascade显示文摘Ledwaba T Dlamini Z Maicker S 2004Biol Chem2004,385,:1
6Drug resistance patterns among HIV infected children and adults failing Kaletra-based regimens in South Africa显示文摘Hunt G Ledwaba J El-Khatib Z 2009Antivir Ther2009,141,:1
7Effectiveness of twenty-five hydroxycholecalciferol in the prevention of tibial dyschondroplasia in ross cockerels depends on dietary calcium level显示文摘Ledwaba M F Roberson K D 2003Poult Sci2003,82,:1
8Molecular genetics of hu- man cervical cancer: role of papillomavirus and the apoptotic cas- cade显示文摘Ledwaba T Dlamini Z Naicker S 2004Biol Chem2004,385,8:1
9Lactic acidosis and symptomatic hyperlactataemia in a randomized trial of first-line therapy in HIV-infected adults in South Africa显示文摘Dlamini J Ledwaba L Mokwena N 2011Antivir Ther2011,16,60:1
10Molecular genetics of human cervical cancer:role of papilloma virus and the apoptotic cascade显示文摘Ledwaba T Dlamini Z NalckerS 2004Biol Chem2004,385,8:1
11Molecular genetics of human cervical cancer:role of papillomavirus and the apoptotic cascade显示文摘Ledwaba T Dlamini Z Naicker S 2004Biol Chem2004,385,:1
12Pre-ART levels of inflammation and coagulation markers are strong predictors of death in a South African cohort with advanced HIV disease显示文摘Ledwaba L Tavel JA Khabo P 0,,:1
13Molecular genetics of human cervical cancer: role of papillomavirus and the apoptotic cascade 显示文摘Ledwaba T Dlamini Z Naicker S 2004Biol Chem2004,385,8:1
14Viremia and drug re- sistance among HIV-1 patients on antiretroviral treatment:a cross- sectional study in Soweto, South Africa 显示文摘El-Khatib Z Ekstrom AM Ledwaba J 2010AIDS2010,24,11:1
15Pre-ART levels of inflammation and coagulation markers are strong predictors of death in a South African cohort with advanced HIV disease显示文摘Ledwaba L Tavel JA Khabo P 0,,:1
16Molecular genetics of human cervical cancer:role of papillomavirus and the apoptotic cascade显示文摘Ledwaba T Dlamini Z Naicker S 2004Biol Chem2004,385,8:1
17Solvent-solvent fractionations of Combretum erythrophyllum(Burch.) leave extract: Studies of their antibacterial, antifungal, antioxidant and cytotoxicity potentials显示文摘Objective: To evaluate the biological activities of Combretum erythrophyllum(C. erythrophyllum) leaf extracts against infectious diseases' pathogenesis and their cytotoxicity potentials. Methods: Powdered leaf material(300 g) of C. erythrophyllum was extracted(1:10 w/v) using acetone to obtain the crude extract. Liquid-liquid fractionation was performed on the crude acetone extract(30 g) using solvents of different polarity. The bioautographic method was used to detect the inhibition of bacterial and fungal growth by active compounds present in the crude and fractions. The extracts were then tested on bacterial strains: Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa; fungal strains: Candida albicans(C. albicans), Cryptococcus neoformans, and Aspergillus fumigatus, by microtitre dilution method for MIC determination. Results: The extracts MIC values ranged between 0.08–2.50 mg/m L against the tested pathogens. Water fraction had the highest activity against bacteria strains, while the fungal assay revealed crude acetone extract and ethyl acetate fraction to be active against C. albicans(1.25 mg/m L), dichloromethane extract against C. albicans and Aspergillus fumigatus(0.16 mg/m L). Extract fractions showed a good antioxidant activity via DPPH, ABTS and hydroxyl radical scavenging assays, in the order: ethyl acetate > water > acetone > dichloromethane > hexane. The toxicity level of crude extract and fractions evaluated in Vero monkey kidney cells ranged from 34–223 μg/m L, while doxorubicin(IC_(50) = 7.19 μg/m L) served as the positive control. Conclusions: It can be concluded that the extracts of C. erythrophyllum are safe for medicinal use in folk medicine for treating infectious and stress related diseases.Fanyana M.Mtunzi Ikechukwu P.Ejidike Imelda Ledwaba Aroke Ahmed Vusumzi E.Pakade Michael J.Klink Sekomeng J.Modise 2017Asian Pacific Journal of Tropical Medicine2017,10,7:0
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