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| 1 | 抑郁症的非药物治疗:系统性综述与证据图显示文摘背景抑郁症非药物治疗的疗效比较目前仍然不清楚。方法我们对一些系统性综述作了概述,回顾了随机对照试验(RCT),比较抑郁症非药物治疗的有效性和认知行为治疗(CBT)。对多个电子数据库在2016年2月之前发表的所有文献进行了检索,不限制语言。成对的评阅人进行资料纳入、数据提炼并评估偏倚的风险。在适用的时候进行了荟萃分析。结果我们收录了367项RCT,纳入了约2000名患者,进行了11种治疗,导出17项独立的头对头比较。通过标准化的量表评估,发现CBT、自然疗法、行为干预与躯体活动干预可以降低抑郁的严重程度。然而,这些非药物干预的相对疗效仍然缺乏。这些干预对临床缓解和复发的效果不清楚。CBT的发生率比抗抑郁药物更低。局限性由于证据缺乏一致性、证据不清或偏倚风险高,导致证据的质量只是低到中等,限制了我们研究结果的可信度。结论抑郁症的非药物治疗能减少抑郁症状,在轻度到重度抑郁症患者中,应当合并抗抑郁药物治疗,一同进行。对于非药物治疗的选择,应当根据患者的价值观、偏好、临床和社会因素来与患者共同作出决定。 | Wigdan H Farah Mouaz Alsawas Maria Mainou Fares Alahdab Magdoleen H Farah Ahmed T Ahmed Essa A Mohamed Jehad Almasri Michael R Gionfriddo Ana Castaneda-Guarderas Khaled Mohammed Zhen Wang Noor Asi Craig N Sawchuk Mark D Williams Larry J Prokop M Hassan Murad Annie LeBlanc | 2017 | 英国医学杂志中文版2017，20，11： | 2 |
| 2 | Changes in interverte-bral disc cross-sectional area with bed rest and space flight显示文摘 | LeBlanc A D Evans H J Schneider V S | 1994 | Spine(Phila Pa 1976)1994，19，7： | 1 |
| 3 | Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight显示文摘 | Lang T LeBlance A Evans H | 2004 | J Bone Miner Res2004，19，6： | 1 |
| 4 | Human mesenchymal stem cells do not differentiate into cardiomyocytes in a cardiac ischemic xenomodel显示文摘 | Grinnemo K H Mansson Broberg A Leblanc K | 2006 | Ann Med2006，38，2： | 1 |
| 5 | Fiber grating sensors 显示文摘 | A D Kersey M A Davis H J Patrick M LeBlanc K P Koo C G Askins M A Putnam E J Friebele | 1997 | Lightwave Technology1997，15，8： | 1 |
| 6 | An ecological assessment of bisphenol A : Evidence from comparative biology 显示文摘 | Crain D A Eriksen M Iguchi T Jobling S Laufer H LeBlanc G A Guillette Jr L J | 2007 | Reproductive Toxicology2007，24，2： | 1 |
| 7 | Apo2L/TRAIL and its death and decoy receptors显示文摘 | LeBlanc H N Ashkenazi A | 2003 | Cell Death Differ2003，10，： | 1 |
| 8 | Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight显示文摘 | LANG T F LEBLANC A D EVANS H J | 2004 | Journal of Bone and Mineral Research2004，19，6： | 1 |
| 9 | Self-Assembling Three-Dimensional Colloidal Photonic Crystal Structure with High Crystalline Quality 显示文摘 | YE Y H LEBLANC F HACHE A | 2001 | Applied Physics Letters2001，78，1： | 1 |
| 10 | Horizontal Connections for Precast Concrete Stear Wails Under Cyclic Deformations-Part 1 : Mild Steel Connecti,ms显示文摘 | Soudki K A Rizkalla S H LeBlanc B | 1995 | PCI Journal1995，40，4： | 1 |
| 11 | Interactions of methyl farnesoate and related compounds with a crustacean retinoid X receptor显示文摘 | WANG Y H LEBLANC G A | 2009 | Molecular and Cellular Endocrinology2009，309，1： | 1 |
| 12 | Horizontal connec- tions for precast concrete shear walls subjected to cycle deformations part 1 :mild steel connections显示文摘 | Soudki K A Rizkalla S H LeBlanc B | 1995 | PCI Jour- nal1995，40，4： | 1 |
| 13 | Cloning and characterization of the retinoid X receptor from a primitive crustacean Daphnia magna 显示文摘 | Wang Y H Wang G LeBlanc G A | 2007 | Gen Comp Endocrinol2007，150，2： | 1 |
| 14 | Horizontal con-nections for precast concrete shear walls subjected to cy-clic deformations part 1 : mild steel connections显示文摘 | Soudki K A Rizkalla S H LeBlanc B | | PCIJournal \995 4{)(4)0，7896，： | 1 |
| 15 | Fiber grating sensors显示文摘 | KERSEY A D DAVIS M A PATRICK H J LeBLANC M KOO K P ASKINS C G PUTNAM M A FRIEBELE E J | 1997 | Journal Lightwave Technology1997，15，8： | 1 |
| 16 | Fiber grating sensors显示文摘 | Kersey A D Davis H J Patrick M LeBlanc | 1997 | J Lightwave Technol1997，15，8： | 1 |
| 17 | Human mesen?chymal stem cells do not differentiate into cardiomyocytes in a cardiac ischemic xenomodel显示文摘 | Grinnemo K H Mansson-Broberg A Leblanc K | 2006 | Ann Med2006，38，2： | 1 |
| 18 | The phytomining and environmental significance of hyperaccumulation of thallium by Iberis intermedia from southern France显示文摘 | Leblanc M Petit D Detain A Robinson B H Brooks R R | 1999 | Econ Geol1999，94，1： | 1 |
| 19 | Horizontalconnections for precast concrete shear walls subjected tocyclic deformations part 1: Mild steel connections 显示文摘 | Soudki K A Rizkalla S H LeBlanc B | 1995 | PCI Journal1995，40，4： | 1 |
| 20 | Apo2L/TRAIL and its death and decoy recptors 显示文摘 | LeBlanc H N Ashkenazi A | 2003 | Cell Death Differ2003，10，1： | 1 |
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