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1Event-related potentials in a Go/Nogo task of abnormal response inhibition in heroin addicts显示文摘Inhibitory control dysfunction is regarded as a core feature in addicts.The major objective of this study was to explore the time course of response inhibition in chronic heroin addicts and provide the neurophysiological evidence of their inhibitory control dysfunction.The amplitudes and latencies of ERP components were studied in fourteen heroin addicts(mean duration of heroin use being(13.54±5.71) years(Mean±SD),average abstinence being((4.67±6.44) months)) and fourteen matched healthy controls with a visual Go/Nogo task.Our results showed that heroin addicts demonstrated significantly larger Go-N2 amplitudes which results in a decreased N2 Go/Nogo effect,but no statistically significant differences were found between heroin addicts and controls in P3.The ERP data suggest that fronto-central areas of heroin addicts were impaired during the inhibition process(200-300 ms) and over-activated to targets.The impaired early process might reflect an abnormal conflict monitoring process in heroin addicts.These results consolidate the inhibitory control dysfunction hypothesis in chronic heroin users.YANG Bo1,YANG SuYong2,ZHAO Lun3,YIN LiuHua1,LIU Xu1& AN ShaSha1 1 Laboratory of Psychology,School of Sociology,China University of Political Science and Law,Beijing 102249,China 2 National Key Laboratory of Cognitive Neurosciences and Learning,Beijing Normal University,Beijing 100875,China 3 Institute of Language,Xuzhou Normal University,Xuzhou 221116,China 2009Science China(Life Sciences)2009,52,8:15
2False belief reasoning in the brain: An ERP study显示文摘Understanding others mind and interpersonal interaction are the cognitive basis of successful social interactions. People's mental states and behaviors rely on their holding beliefs for self and others. To investigate the neural substrates of false belief reasoning, the 32 channels event-related potentials (ERP) of 14 normal adults were measured while they understood false-belief and true belief used de-ceptive appearance task. After onset of the false-belief or true-belief questions, N100, P200 and late negative component (LNC) were elicited at centro-frontal sites. Compared with true belief, false belief reasoning elicited significant declined LNC in the time window from 400 to 800 ms. The source analysis of difference wave (False minus True) showed a dipole located in the middle cingulated cortex. These findings show that false belief reasoning probably included inhibitive process.WANG YiWen1,2,3, LIU Yan2, GAO YanXia2, CHEN Jing2, ZHANG Wenxin2 & LIN ChongDe3 1 Research Center of Learning Science, Southeast University, Nanjing 210096, China 2 School of Psychology, Shandong Normal University, Jinan 250014, China 3 The State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China 2008Science China(Life Sciences)2008,51,1:7
3Global perception depends on coherent work of bilateral visual cortices: Transcranial magnetic stimulation (TMS) studies显示文摘Previous research suggests that the right and left hemispheres dominate global and local perception of hierarchical patterns, respectively. The current work examined whether global perception of hierarchi-cal stimuli requires coherent work of bilateral visual cortices using transcranial magnetic stimulation (TMS). Subjects discriminated global or local properties of compound letters in Experiment 1. Reaction times were recorded when single-pulse real TMS or sham TMS was delivered over the left or right visual cortex. While a global precedence effect (i.e., faster responses to global than local targets and stronger global-to-local interference than the reverse) was observed, TMS decreased global-to-local interference whereas increased local-to-global interference. Experiment 2 ruled out the possibility that the effects observed in Experiment 1 resulted from perceptual learning. Experiment 3 used compound shapes and observed TMS effect similar to that in Experiment 1. Moreover, TMS also slowed global RTs whereas speeded up local RTs in Experiment 3. Finally, the TMS effects observed in Experiments 1 and 3 did not differ between the conditions when TMS was applied over the left and right hemispheres. The results support a coherence hypothesis that global perception of compound stimuli depends upon the co-herent work of bilateral visual cortices.ZHANG Xin1 & HAN ShiHui1,2 1 Department of Psychology, Peking University, Beijing 100871, China 2 Learning & Cognition Lab, Capital Normal University, Beijing 100875, China 2007Science China(Life Sciences)2007,50,4:2
4of classifiers : theory, algorithms, and their application to human-computer interaction 显示文摘COHEN I COZMAN Semisupervised learning F G SEBE N etal 2004IEEE Transactions on Pattern Analysis and Machine Intelligence2004,26,12:1
5HER-2/neu expression as a predictor of response to neoadjuvant docetaxel in patients with operable breast carcinoma显示文摘Learn P A Yeh I T McNutt M 2005Cancer2005,103,11:1
6Preliminary resulm from a prospective analysis of 1194 laparoscopic - assisted colectomies显示文摘Bennett CL Stryker SJ Ferreira MR :The learning curve for laparoscopic colorectal surgery 1997Arch Surg1997,132,:1
7Strategic Investment and Technology Spillovers显示文摘NORI TARUI AND STEPHEN POLASKY.Environmental Regulation with Learning 0,,:1
8Laparoscopic hepatic resection using saline-enhanced electrocautery permits short hospital stays显示文摘Learn PA Bowers SP Watkins KT 2006J Gastrointest Surg2006,10,3:1
9A Wavelet Packet Approach to Transient Signal Classification显示文摘Learned Rachel E Willsky Alan S 1995Applied and Computational Harmonic Analysis1995,,2:1
10The fourth New Zealand cataract and refractive surgery survey: 2007 显示文摘Pick ZS Learning DV Elder MJ 2008Clin Experiment Ophthalmol2008,36,:1
11Highprevalence of peripheral retinal vascular anomalies infamily members of patients with familial exudativevitreoretinopathy 显示文摘Kashani AH Learned D Nudleman E 2014Ophthalmology2014,121,1:1
12Ribosomal SNA Variation Within and Among Plant Population显示文摘Schaal B A Learn G H Jr 1988Ann Missouri Bot Gard1988,,:1
13HER-2 expressing as a predictor of response to neoadjuvant docetaxel in patient with operable breast carcinoma显示文摘Learn PA Yehi T Mu Nuttm 2005Cancer2005,103,11:1
14HER-2/neu expression as a predictor of response to neoadjuvant docetaxel in patients with operable breast carcinoma显示文摘Learn PA Yeh IT McNutt M 2005Cancer2005,103,11:1
1584显示文摘Bate E Hommes J Duvivier R Problem-based learning (PBL): Getting the most out of your students-their roles and respon- sibilities: AMEE Guide No 2014Medical Teacher2014,36,1:1
16Voluntary control of heart rate and rhythm in subjects with premature ventricular contractions显示文摘 Miller NE Learned 1977Brit Heart J1977,39,:1
17Impairments After a Binge Regimen of Methamphetamine in Rats: Possible Involve - ment of Striatal Dopamine 显示文摘Alicia Izquierdo Annabelle Reversal-Specific Learning M Belcher Loft Scott 2010Neuropsyehopharmacology2010,35,:1
18Guest editorial Vapnik-chervonen- kis(VC) learning theory and its applications显示文摘Learning V C V 1999IEEE Transactions on Neural Netwoks1999,10,5:1
19Rates and patterns of chloro- plast DNA evolution显示文摘Clegg M T Gaut B S Learn G H 1994Proceedings of the National Academy of Sciences1994,91,15:1
20Peripheral neuropathy induced by metronidazole显示文摘 1994Ann Pharmacother1994,28,4:1
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