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| 1 | Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis显示文摘Wnt/ 尾 - catenin 调整与肿瘤有关的细胞的功能开始和前进,房间增长,区别,幸存,和粘附。尾 -Catenin 独立的 Wnt 小径被建议了调整房间极性和移植,包括转移。在这评论,我们在肿瘤前进讨论 catenin 依赖的尾 - 和独立人士发信号小径的可能的角色,与他们 Rho 家庭 GTPases,改变的细胞骨架,和与房间房间粘附和 cilia/ciliogenesis 的关系的规定上的一个重音。 | Shih-Lei Lai Andy J Chien Randall T Moon | 2009 | Cell Research2009，19，5： | 15 |
| 2 | TALEN-based generation of a cynomolgus monkey disease model for human microcephaly显示文摘基因在非人类的首领编辑可以为在人探索病原学和遗传上基于的神经病学的混乱的治疗学的策略导致珍贵模型。然而,仔细在人模仿病理学、行为的赤字的神经病学的混乱的一个猴子模型成功地还没被产生了。Microcephalin 1 (MCPH1 ) 在人的大脑,和智力迟钝伴随的 MCPH1 变化原因头小畸型的进化被含有。这里,我们产生了用抄写带 biallelic MCPH1 变化的一只 cynomolgus 猴子(Macaca fascicularis ) 像使活跃之物的受动器核酸酶。猴子概括了大多数在病人观察的重要临床的特征,包括在头圆周,早熟的染色体冷凝作用(PCC ) ,语料库 callosum 的发育不全和上面的手足 spasticity 的显著减小。而且,在变异的真皮的成纤维细胞的 MCPH1 的 overexpression 救了 PCC 症候群。这个猴子模型可以帮助我们阐明在人的头小畸型并且更好的致病的 MCPH1 的角色在首领大脑尺寸的进化理解这蛋白质的功能。 | Qiong Ke Weiqiang Li Xingqiang Lai Hong Chen Lihua Huang Zhuang Kang Kai Li Jie Ren Xiaofeng Lin Haiqing Zheng Weijun Huang Yunhan Ma Dongdong Xu Zheng Chen Xinming Song Xinyi Lin Min Zhuang Tao Wang Fengfeng Zhuang Jianzhong Xi Frank Fuxiang Mao Huimin Xia Bruce T Lahn Qi Zhou Shihua Yang Andy Peng Xiang | 2016 | Cell Research2016，26，9： | 13 |
| 3 | Coronavirus as a possible cause of severe acute respiratory syndrome显示文摘 | Peris J S M Lai S T Poon L L M | 2003 | Lancet2003，361，： | 2 |
| 4 | Coronavirus as a possible cause of severe respiratory syndrome显示文摘 | PERIS J S M LAI S T POON L L M | 2003 | Lancet2003，361，9366： | 2 |
| 5 | SARS study group:coro-navirus as a possible cause of severe acute respiratory syndrome显示文摘 | Peiris J S Lai S T Poon L L | 2003 | Lancet2003，361，： | 2 |
| 6 | Corrosion protection of magnesium by electroactive polypyrrole/paint coatings显示文摘 | Truong V T Lai P K Moore B T | 2000 | Synthetic Metals2000，111，： | 2 |
| 7 | Fuzzy weighting optimization with several objective function in structual design显示文摘 | Shih C J Lai T K | 1994 | Computer & Structures1994，52，5： | 2 |
| 8 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 9 | Excited - state properties of dioxorhenium(V) generation and reactivity of dioxorhenium(Ⅵ) 显示文摘 | Che C M Chung W C Lai T F | 1989 | Inorg Chem1989，28，： | 1 |
| 10 | Upregulation of stromal cell-derived factor 1 (SDF-1) expression in microvasculature endothelial cells in retinal ischemia-reperfusion injury显示文摘 | Lai P Li T Yang J | 2008 | Graefe''s Arch Clin Exp Ophthalmol2008，246，12： | 1 |
| 11 | Banana biomass as potential renewable energy resource: A Malaysian case study 显示文摘 | TOCK J Y LAI C L LEE K T | 2010 | Renewable and Sustainable Energy Re- views2010，14，2： | 1 |
| 12 | Application of evolutionary programming to reative power planning comparison with nonlinear programming approach显示文摘 | LAI L L MAJ T | 1997 | IEEE Trans on Power System1997，12，1： | 1 |
| 13 | The influence of green innovation performance on corporate advantage in Taiwan显示文摘 | Chen Y S Lai S B Wen C T | 2006 | Journal of Business Ethics2006，67，： | 1 |
| 14 | A Systematic Data Integration Techniquefor Mold - Surface Polishing Processes Planning显示文摘 | Lai H Y Huang C T | 2007 | Internation-al Journal of Advanced Manufacturing Technology2007，31，： | 1 |
| 15 | Surface and catalytic properties of doped tin oxide nanoparticles显示文摘 | Wang C T Lai D L Chen M T | 2010 | Applied Surface Science2010，257，： | 1 |
| 16 | Dentification of novel DNA methylation markers in cervical cancer显示文摘 | Lai H C Lin Y W Huang T H M | | 0，，01： | 1 |
| 17 | Implication of light sources and microbial activities on degradation of sulfonamides in water and sediment from a marine shrimp pond显示文摘 | Lai H T Wang T S Chou C C | | 0，，8： | 1 |
| 18 | Real-time frequency and harmonic evaluation using artificial neural networks显示文摘 | LAI L L TSE C T CHAN W L | 1999 | IEEE Transactions on Power Delivery1999，14，1： | 1 |
| 19 | Similarity in percent body fat between white and Vietnamese women:Implication for a universal definition of obesity显示文摘 | Ho-Pham L T Lai T Q Nguyen N D | 2010 | Obesity(Silver Spring)2010，18，6： | 1 |
| 20 | Revised recommenda- tions on screening for chloroquine and hydroxychloroquine reti- nopathy显示文摘 | Marmor M F Kenner U Lai T Y | 2011 | Ophthalmology2011，118，2： | 1 |
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