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| 1 | Diclofop-methyl affects microbial rhizosphere community and induces systemic acquired resistance in rice显示文摘Diclofop-methyl(DM),a widely used herbicide in food crops,may partly contaminate the soil surface of natural ecosystems in agricultural area and exert toxic effects at low dose to nontarget plants.Even though rhizosphere microorganisms strongly interact with root cells,little is known regarding their potential modulating effect on herbicide toxicity in plants.Here we exposed rice seedlings(Xiushui 63) to 100 μg/L DM for 2 to 8 days and studied the effects of DM on rice rhizosphere microorganisms,rice systemic acquired resistance(SAR) and rice-microorganisms interactions.The results of metagenomic 16 S rDNA Illumina tags show that DM increases bacterial biomass and affects their community structure in the rice rhizosphere.After DM treatment,the relative abundance of the bacterium genera Massilia and Anderseniella increased the most relative to the control.In parallel,malate and oxalate exudation by rice roots increased,potentially acting as a carbon source for several rhizosphere bacteria.Transcriptomic analyses suggest that DM induced SAR in rice seedlings through the salicylic acid(but not the jasmonic acid) signal pathway.This response to DM stress conferred resistance to infection by a pathogenic bacterium,but was not influenced by the presence of bacteria in the rhizosphere since SAR transcripts did not change significantly in xenic and axenic plant roots exposed to DM.The present study provides new insights on the response of rice and its associated microorganisms to DM stress. | Si Chen Xingxing Li Michel Lavoie Yujian Jin Jiahui Xu Zhengwei Fu Haifeng Qian | 2017 | Journal of Environmental Sciences2017，29，1： | 8 |
| 2 | Microarray,SAGE and their applications to cardiovascular diseases显示文摘The wealth of DNA data generated by the human genome project coupling with recently invented high-throughput gene expression profiling techniques has dramatically sped up the process for biomedical researchers on elucidating the role of genes in human diseases. One powerful method to reveal insight into gene functions is the systematic analysis of gene expression. Two popular high-throughput gene expression technologies, microarray and Serial Analysis of Gene Expression (SAGE) are capable of producing large amounts of gene expression data with the potential of providing novel insights into fundamental disease processes, especially complex syndromes such as cardiovascular disease, whose etiologies are due to multiple genetic factors and their interplay with the environment. Microarray and SAGE have already been used to examine gene expression patterns of cell-culture, animal and human tissues models of cardiovascular diseases. In this review, we will first give a brief introduction of microarray and SAGE technologies and point out their limitations. We will then discuss the major discoveries and the new biological insightsthat have emerged from their applications to cardiovascular diseases. Finally we will touch upon potential challenges and future developments in this area. | SHUI QING YE, TERA LAVOIE, DAVID C USHER, LI Q. ZHANG1 Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD 21224, USA2Department of Biological Science, University of Delaware, Newark, DE 19716, USA | 2002 | Cell Research2002，12，2： | 5 |
| 3 | Human viral pathogens are pervasive in wastewater treatment center aerosols显示文摘Wastewater treatment center(WTC) workers may be vulnerable to diseases caused by viruses, such as the common cold, influenza and gastro-intestinal infections. Although there is a substantial body of literature characterizing the microbial community found in wastewater, only a few studies have characterized the viral component of WTC aerosols,despite the fact that most diseases affecting WTC workers are of viral origin and that some of these viruses are transmitted through the air. In this study, we evaluated in four WTCs the presence of 11 viral pathogens of particular concern in this milieu and used a metagenomic approach to characterize the total viral community in the air of one of those WTCs. The presence of viruses in aerosols in different locations of individual WTCs was evaluated and the results obtained with four commonly used air samplers were compared.We detected four of the eleven viruses tested, including human adenovirus(h Ad V),rotavirus, hepatitis A virus(HAV) and Herpes Simplex virus type 1(HSV1). The results of the metagenomic assay uncovered very few viral RNA sequences in WTC aerosols, however sequences from human DNA viruses were in much greater relative abundance. | Evelyne Brisebois Marc Veillette Vanessa Dion-Dupont Jacques Lavoie Jacques Corbeil AlexANDer Culley Caroline Duchaine | 2018 | Journal of Environmental Sciences2018，30，5： | 5 |
| 4 | Effect of temperature in the conversion of methanol to olefins (MTO) using an extruded SAPO-34 catalyst显示文摘methanol-to-olefin (MTO ) 反应在凳子规模被调查,用渗出的催化剂的改正床反应堆商业 SAPO-34 创作了(65 重量百分比, wt-%) 在一个非结晶的 SiO2 矩阵(35 wt-%) 嵌入。质地性质,酸味和纯 SAPO-34 和它的渗出的形式(E-SAPO-34 ) 的水晶结构被分析,结果显示挤出步没影响催化剂的性质。随后, E-SAPO-34 在在 300 半胱氨酸和 500 之间的一个温度范围被测试,胱氨酸是 5 f rGO 上的高密度的 AgNPs 结果到快反应( 393 ? nA/s )并且恢复率( 399 ? nA/s )与甚至在 1 的低偏导的电压的优秀周期的稳定性?[ V ]由于吗有效?? | Ignacio Jorge Castellanos-Beltran Gnouyaro Palla Assima Jean-Michel Lavoie | 2018 | Frontiers of Chemical Science and Engineering2018，12，2： | 5 |
| 5 | Dynamics of hepatic and intestinal cholesterol and bile acid pathways: The impact of the animal model of estrogen deficiency and exercise training显示文摘Plasma cholesterol level is determined by a complex dynamics that involves transport lipoproteins which levels are tightly dependent on how the liver and the intestine regulate cholesterol and biliary acid metabolism. Regulation of cholesterol and biliary acids by the liver and the intestine is in turn coupled to a large array of enzymes and transporters that largely influence the inflow and the outflow of cholesterol and biliary acids through these organs. The activity of the key regulators of cholesterol and biliary acids may be influenced by several external factors such as pharmacological drugs and the nutritional status. In recent years, more information has been gathered about the impact of estrogens on regulation of cholesterol in the body. Exposure to high levels of estrogens has been reported to promote cholesterol gallstone formation and women are twice as likely as men to develop cholesterol gallstones. The impact of estrogen withdrawal, such as experienced by menopausal women, is therefore of importance and more information on how the absence of estrogens influence cholesterol regulation is started to come out, especially through the use of animal models. An interesting alternative to metabolic deterioration due to estrogen deficiency is exercise training. The present review is intended to summarize the present information that links key regulators of cholesterol and biliary acid pathways in liver and intestine to the absence of estrogens in an animal model and to discuss the potential role of exercise training as an alternative. | Jean-Marc Lavoie | 2016 | World Journal of Hepatology2016，8，23： | 4 |
| 6 | Nanoengineered Shear-Thinning Hydrogel Barrier for Preventing Postoperative Abdominal Adhesions显示文摘More than 90%of surgical patients develop postoper-ative adhesions,and the incidence of hospital re-admissions can be as high as 20%.Current adhesion barriers present limited efficacy due to difficulties in application and incompatibility with minimally invasive interventions.To solve thisclinical limitation,we developed an injectable and sprayable shear-thinning hydrogel barrier(STHB)composed of silicate nanoplatelets and poly(ethylene oxide).We optimized this technology to recover mechanical integrity after stress,enabling its delivery though inject-able and sprayable methods.We also demonstrated limited cell adhesion and cytotoxicity to STHB compositions in vitro.The STHB was then tested in a rodent model of peritoneal injury to determine its e cacy preventing the formation of postoperative adhesions.After two weeks,the peritoneal adhesion index was used as a scoring method to determine the formation of postoperative adhesions,and STHB formulations presented superior e cacy compared to a commercially available adhesion barrier.Histological and immunohistochemical examination showed reduced adhesion formation and minimal immune infiltration in STHB formulations.Our technology demonstrated increased e cacy,ease of use in complex anatomies,and compatibility with di erent delivery methods,providing a robust universal platform to prevent postoperative adhesions in a wide range of surgical interventions. | Guillermo U.Ruiz-Esparza Xichi Wang Xingcai Zhang Sofia Jimenez-Vazquez Liliana Diaz-Gomez Anne-Marie Lavoie Samson Afewerki Andres AFuentes-Baldemar Roberto Parra-Saldivar Nan Jiang Nasim Annabi Bahram Saleh Ali K.Yetisen Amir Sheikhi Thomas H.Jozefiak Su Ryon Shin Nianguo Dong Ali Khademhosseini | 2021 | Nano-Micro Letters2021，13，12： | 2 |
| 7 | Enhanced peel resistance of fiber reinforced phenolic foams显示文摘 | Hongbin Shen Andre J. Lavoie Steven R. Nutt | 2003 | Composites Part A2003，，10： | 2 |
| 8 | Preventable death evaluation of the appropriateness of the on-site trauma care provided by urgencies-santé physicians显示文摘 | Boukas S Lavoie A | 1995 | J Trauma1995，39，： | 1 |
| 9 | The impact of premorbidconditions on temporal pattern and location of adult blunt trauma hospital deaths显示文摘 | Bergeron E Lavoie A | 2007 | J Trauma2007，63，： | 1 |
| 10 | Predictors and timing of hypotension and bradycardia after carotid artery stenting显示文摘 | Lavoie P Rutledge J Dawoud MA | 2008 | AJNR Am J Neuroradiol2008，29，10： | 1 |
| 11 | Solubilization of cyclosporin A in dextran-g-polyethyleneglycolalkyl ether polymeric micelles显示文摘 | Francis M F Lavoie L Winnik F M | 2003 | Eur J Pharm Biopharm2003，56，3： | 1 |
| 12 | Monitoring the earthquake activity in an area with shale gas potential in Southeastern New Brunswick, Canada显示文摘 | Lamontagne M Lavoie D Ma S Burke KBS Bastow I | 2015 | Seismological Research Letters2015，86，4： | 1 |
| 13 | Ultrasound as a deterrent to Rattus norvegicus显示文摘 | Lavoie GK Glahn JF | 1977 | J Stored Prod Res1977，13，1： | 1 |
| 14 | Prednisone prevents atrial fibrillation promotion by atrial tachyeardia remodeling in dogs 显示文摘 | Shiroshita-Takeshita A Brundel BJ Lavoie J | 2006 | Cardiovasc Res2006，69，4： | 1 |
| 15 | In vivo activity of mutacin B-Ny266显示文摘 | MOTA-MEIRA M MORENCY H LAVOIE M C | 2005 | J Antimicrob Chemother2005，56，5： | 1 |
| 16 | On the kinematic design of spherical 3-dof parallel manipulators显示文摘 | Gosselin C M Lavoie E | 1993 | The International Journal of Robotics Research1993，12，4： | 1 |
| 17 | Effects of systemic corticoRteroids on cutaneous histamine secretion and histamine-R releasing factor in patients with chronic idiopathic urticaria显示文摘 | Paradis L Lavoie A Brunet C | 1996 | Clin Exp Allergy1996，26，： | 1 |
| 18 | Conformational changes of pediocin in an aqueous medium monitored by Fourier transform infrared spectroscopy: a biological im- plication显示文摘 | Helene Gaussier Marc Lavoie Muriel Subirade | 2003 | International Journal of Biological Macromolecules2003，32，12： | 1 |
| 19 | Cardiopulmonary resuscitation:Errors- made by prehospital emergency medical personnel显示文摘 | Liberman M Lavoie A Mulder D | 1999 | Resuscitation1999，42，1： | 1 |
| 20 | Pedunculopontine nucleus in the squirrel monkey:cholinergic and glutamatergic projections to the substantia nigra显示文摘 | Parent A | 1994 | J Comp Neurol1994，344，2： | 1 |
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