|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Complications of modern pancreaticoduodenectomy:A systematic review and meta-analysis显示文摘Background:In the past decades,the perioperative management of patients undergoing pancreaticoduo-denectomy(PD)has undergone major changes worldwide.This review aimed to systematically determine the burden of complications of PD performed in the last 10 years.Data sources:A systematic review was conducted in PubMed for randomized controlled trials and ob-servational studies reporting postoperative complications in at least 100 PDs from January 2010 to April 2020.Risk of bias was assessed using the Cochrane RoB2 tool for randomized studies and the method-ological index for non-randomized studies(MINORS).Pooled complication rates were estimated using random-effects meta-analysis.Heterogeneity was investigated by subgroup analysis and meta-regression.Results:A total of 20 randomized and 49 observational studies reporting 63229 PDs were reviewed.Mean MINORS score showed a high risk of bias in non-randomized studies,while one quarter of the ran-domized studies were assessed to have high risk of bias.Pooled incidences of 30-day mortality,overall complications and serious complications were 1.7%(95%CI:0.9%-2.9%;I 2=95.4%),54.7%(95%CI:46.4%-62.8%;I 2=99.4%)and 25.5%(95%CI:21.8%-29.4%;I 2=92.9%),respectively.Clinically-relevant postopera-tive pancreatic fistula risk was 14.3%(95%CI:12.4%-16.3%;I 2=92.0%)and mean length of stay was 14.8 days(95%CI:13.6-16.1;I 2=99.3%).Meta-regression partially attributed the observed heterogeneity to the country of origin of the study,the study design and the American Society of Anesthesiologists class.Conclusions:Pooled complication rates estimated in this study may be used to counsel patients scheduled to undergo a PD and to set benchmarks against which centers can audit their practice.However,cautious interpretation is necessary due to substantial heterogeneity. | Stamatios Kokkinakis Evangelos I Kritsotakis Neofytos Maliotis Ioannis Karageorgiou Emmanuel Chrysos Konstantinos Lasithiotakis | 2022 | Hepatobiliary & Pancreatic Diseases International2022，21，6： | 2 |
| 2 | Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide显示文摘 | Sinnberg T Lasithiotakis K Niessner H | 2009 | J Invest Dermatol2009，129，6： | 1 |
| 3 | Combined targeting of MAPK and AKT signalling pathways is a promising strategy for mela- noma treatment显示文摘 | Meier F Busch S Lasithiotakis K | 2007 | Br J Dermatal2007，156，6： | 1 |
| 4 | Differential telomerase expression in idiopathic pulmonary fibrosis and non- small cell lung cancer 显示文摘 | Antoniou KM Samara KD Lasithiotaki I | 2013 | Oncol Rep2013，30，6： | 1 |
| 5 | Application of an independent parallel reactions model on the annealing kinetics to irradiated graphite waste显示文摘 | Lasithiotakis M Marsden B Marrow J | 2008 | J Nucl Mater2008，，381： | 1 |
| 6 | Hyperther- mic isolated limb perfusion for recurrent melanomas and soft tissue sarcomas: feasibility and reproducibility in a multi-institutional Hellenic collaborative study 显示文摘 | Lasithiotakis K Economou G Gogas H | 2010 | Oncol Rep2010，23，4： | 1 |
| 7 | The inci dence and mortality of cutaneous melanoma in Southern Ger- many~ trends by anatomic site and pathologic characteristics, 1976 to 2003 显示文摘 | Lasithiotakis KG Leiter U Gorkievicz R | 2006 | Cancer2006，107，6： | 1 |
| 8 | Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells显示文摘 | Lasithiotakis K G Sinnberg T W Schittek B | 2008 | J Invest Dermatol2008，128，8： | 1 |
| 9 | Differential te- lomerase expression in idiopathic pulmonary fibrosis and non - small cell lung cancer显示文摘 | Antoniou KM Samara KD Lasithiotaki I | 2013 | Oncol Rep2013，30，6： | 1 |
| 10 | Clear cell sar- coma of the jejunum : a case report 显示文摘 | Lasithiotakis K Protonotarios A Lazarou V | 2013 | World J Surg Oncol2013，11，： | 1 |
| 11 | Meta-analysis of randomized trials on single-incision laparoscopic versus conventional laparoscopic appendectomy显示文摘 | Stavros A. Antoniou Oliver O. Koch George A. Antoniou Konstantinos Lasithiotakis George E. Chalkiadakis Rudolph Pointner Frank A. Granderath | 2013 | The American Journal of Surgery2013，，： | 1 |
| 12 | Determinants of sur- vival in patients with brain metastases from cutaneous melanoma 显示文摘 | Staudt M Lasithiotakis K Leiter U | 2010 | Br J Cancer2010，102，8： | 1 |
| 13 | Inhibition of PI3K-AKT -mTOR signaling sensitizes melanoma cells to cisplatin andtemozolomide显示文摘 | SinnbergT Lasithiotakis K Niessner H | 2009 | J Invest Dermatol2009，129，6： | 1 |
| 14 | inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide显示文摘 | Sinnberg T Lasithiotakis K Niessner H | 2009 | J Invest Dermatol2009，129，6： | 1 |
| 15 | Age and gender are significant independent predictors of survival in primary cutaneous melanoma 显示文摘 | Lasithiotakis K Leiter U Meier F | 2008 | Cancer2008，112，8： | 1 |
| 16 | LigaSure ver- sus damp-and-tie thyroidectomy for benign nodular disease 显示文摘 | Petrakis IE Kogerakis NE Lasithiotakis KG | 2004 | Head Neck2004，26，10： | 1 |
| 17 | Combined inhibition of MAPK and roTOR signaling inhibits growth, induces cell death, and abrogates in vasive growth of melanoma cells显示文摘 | Lasithiotakis KG Sinnberg TW Schittek B | 2008 | J Invest Dermatol2008，128，8： | 1 |
| 18 | Cutaneous melanoma in the elderly : epidemiology, prognosis and treatment 显示文摘 | Lasithiotakis KG Petrakis IE Garbe C | 2010 | Melanoma Res2010，20，： | 1 |
| 19 | Age and gender are significant independent predictors of survival in primary cutaneous melanoma显示文摘 | Lasithiotakis K Leiter U Meier F | 2008 | Cancer2008，112，8： | 1 |
| 20 | Inhibition of PI3K- AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide 显示文摘 | Sinnberg T Lasithiotakis K Niessner H | 2009 | J Invest Dermatol2009，129，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员