|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 2 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 3 | Molecular phylogenetics of Squamata: the position of snakes, amphisbaenians, and dibamids, and the root of the squamate tree显示文摘 | Townsend T M Larson A Louis E | 2004 | Systematic Biology2004，53，5： | 1 |
| 4 | SAUNA--A system for automatic sampling, processing, and analysis of radioactive xenon显示文摘 | RINGBOM A LARSON T AXELSSON A | 2003 | Nuel Instrum Methods A2003，508，： | 1 |
| 5 | Nephrectomy induced chronic renal insufficiency is associated with increased risk of cardiovascular death and death from any cause in patients with localized cT1b renal masses显示文摘 | WEIGHT C J LARSON B T FERGANY A F | 2010 | J Urol2010，183，4： | 1 |
| 6 | Identification of mRNAs expressed in tumor infiltrating lymphocytes by a strategy for rapid and high through put screening显示文摘 | Li B Chang T Larson A | 2000 | Gene2000，255，2： | 1 |
| 7 | Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson’s disease: an open-label, phase I trial显示文摘 | William J Marks Jill L Ostrem Leonard Verhagen Philip A Starr Paul S Larson Roy AE Bakay Robin Taylor Deborah A Cahn-Weiner A Jon Stoessl C Warren Olanow Raymond T Bartus | 2008 | Lancet Neurology2008，，5： | 1 |
| 8 | SAUNA: A system for automatic sampling processing and analysis of radioac- tive xenon显示文摘 | RINGBOM A LARSON T AXELSSON A | 2003 | Nuclear Instruments and Methods in Physics Re- search Section A2003，508，3： | 1 |
| 9 | Ne- phrectomy induced chronic renal insufficiency is associ- ated with increased risk of cardiovascular death and death from any cause in patients with localized cTlb re- nal masses显示文摘 | Weight C J Larson B T Fergany A F | 2010 | J Urol2010，183，4： | 1 |
| 10 | Calcium carbonate saturation index and alkalinity interpretations 显示文摘 | LARSON T E BUSWELL A M | 1942 | Journal of American Water Works Association1942，34，11： | 1 |
| 11 | Nephrectomy induced chronic renal insufficiency is associated with increased risk of cardiovascular death and death from any cause in pa- tients with localized cTlb renal masses 显示文摘 | Weight C J Larson B T Fergany A F Gao T Lane B R Campbell S C | 2010 | J Urol2010，183，： | 1 |
| 12 | Feeding value of wet distillers byproducts for finishing ruminants显示文摘 | Larson E M Stock R A Klopfenstein T J | 1993 | Journal of Animal Science1993，71，： | 1 |
| 13 | Hybrid plasmonic magnetic nanoparticles as molecular specific agents for MRI/optical imaging and photothermal therapy of cancer cells显示文摘 | Larson T A James B Aaron J | 2007 | Nanotechnology2007，18，32： | 1 |
| 14 | Molecular phylogeneties of Squamata : the position of snakes, am- phisbaenians ,and dibamids ,and the root of the squamate tree显示文摘 | TOWNSEND T M LARSON A LOUIS E | 2004 | Systematic Biology2004，53，5： | 1 |
| 15 | SPARC gene expression is repressed in human urothelial cells (UROtsa) exposed to or malignantly transformed by cadmium or arsenite显示文摘 | Larson J Yasmin T Sens D A | 2010 | Toxicol Lett2010，199，2： | 1 |
| 16 | AUNA: A system for automatic sampling, processing and analysis of radioactive xenon显示文摘 | RINGBOM A LARSON T AXELSSON A | 2003 | Nuclear Instruments and Methods in Physics Research A2003，508，： | 1 |
| 17 | Identification of mRNAs expressedin tumuor-infiltrating lymphocytes by a strategy for rapid and highthroughput screening显示文摘 | Li B Chang T Larson A | 2000 | Gene2000，255，2： | 1 |
| 18 | A heuristic approach to warehouse layout with class based storage 显示文摘 | Larson T N March H Kusiak A | 1997 | IIE Transactions1997，29，： | 1 |
| 19 | Diagnosing groups : The pooling, management, and im- pact of shared and unshared case information in team - based medical decision making 显示文摘 | Larson J R Christensen C Franz T M Abbott A S | 1998 | Journal of Personal- ity & Social Psychology1998，，75： | 1 |
| 20 | A prospective study of the accu- racy of 18Fluorodeoxyglueose positron emission tomography (18FDG PET) in identifying sites of metastasis prior to pelvic exenteration 显示文摘 | Husain A Akhurst T Larson S | 2007 | Gynecol Oncol2007，106，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员