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11篇 您的检索式:作者名="Landsmann"
    题名 作者 年代 出处 被引量
1Epigenetic and non-epigenetic mode of SIRT1 action during oocyte meiosis progression显示文摘Background: SIRT1 histone deacetylase acts on many epigenetic and non-epigenetic targets. It is thought that SIRT1 is involved in oocyte maturation;therefore, the importance of the ooplasmic SIRT1 pool for the further fate of mature oocytes has been strongly suggested. We hypothesised that SIRT1 plays the role of a signalling molecule in mature oocytes through selected epigenetic and non-epigenetic regulation.Results: We observed SIRT1 re-localisation in mature oocytes and its association with spindle microtubules.In mature oocytes, SIRT1 distribution shows a spindle-like pattern, and spindle-specific SIRT1 action decreasesα-tubulin acetylation. Based on the observation of the histone code in immature and mature oocytes, we suggest that SIRT1 is mostly predestined for an epigenetic mode of action in the germinal vesicles(GVs) of immature oocytes. Accordingly, BML-278-driven trimethylation of lysine K9 in histone H3 in mature oocytes is considered to be a result of GV epigenetic transformation.Conclusions: Taken together, our observations point out the dual spatiotemporal SIRT1 action in oocytes,which can be readily switched from the epigenetic to non-epigenetic mode of action depending on the progress of meiosis.Jan Nevoral Lukas Landsmann Miriam Stiavnicka Petr Hosek Jiri Moravec Sarka Prokesova Hedvika Rimnacova Eliska Koutna Pavel Klein Kristyna Hoskova Tereza Zalmanova Tereza Fenclova Jaroslav Petr Milena Kralickova 2019Journal of Animal Science and Biotechnology2019,10,4:3
2Establishment of callus and cell suspension cultures of Opunia ficus-indica显示文摘Llamoca-Zarate Studart-Guimaraes R M Landsmann C J 1999Plant Cell Tissue & Organ Culture1999,58,2:2
3Change of RBC-stiffness and Relaxation-time in Diabetic and Non-diabetic Poad Patients During Treatment with Ginkgo Biloba Extract EGB 761 显示文摘ARTMANN G LANDSMANN B LI L A 1995B iorheology1995,32,:1
4Smart Inorganic Surfactants: More than Surface Tension显示文摘Steve Landsmann Martin Wessig Marius Schmid Helmut C?lfen Sebastian Polarz 2012Angew. Chem. Int. Ed2012,,24:1
5Design consideration and probes for fluorescence resonance energy transfer studies显示文摘Sinev M Landsmann P Sineva E 0,,03:1
6Somaclonal variation in Solanum tuberosum detected at the molecular level显示文摘J. Landsmann H. Uhrig 1985Theoretical and Applied Genetics1985,,3:1
7Credibility evaluation for the exponential dispersion family显示文摘Landsmann Z 1999Insurance: Mathematics and Economics1999,24,1:1
8Plasmocytoma of the ureter a rare cause of hydronephrosis : ease report and re- view of the literature 显示文摘Landsmann S Todorov J Streitberg UV 2009Aktuelle Urol2009,40,:1
9Children's understanding of notations as domains of knowledge versus referential-communicative tools显示文摘Landsmann L T Karmiloff-Smith A 1992Cognitive Development1992,7,3:1
10Design consideration and probes for fluorescence resonance energy transfer studies显示文摘SINEV M LANDSMANN P SINEVA E 2000Bioconjug Chem2000,11,:1
11Somaclonal variation in Solanum tuberosum detected at the molecular level显示文摘 Uhrig H 1985Theoretical & Applied Genetics1985,71,3:1
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