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| 1 | 培美曲塞或多西他赛联合卡铂治疗吉非替尼耐药的晚期肺腺癌患者的疗效显示文摘目的:观察培美曲塞或多西他赛联合卡铂治疗吉非替尼耐药的晚期肺腺癌患者的疗效和安全性。方法:56例吉非替尼耐药的晚期(Ⅲ~Ⅳ期)肺腺癌患者中,28例采用培美曲塞联合卡铂化疗(培美曲塞组),28例采用多西他赛联合卡铂化疗(多西他赛组),21 d为1个化疗周期,2个化疗周期后评估疗效及不良反应,并进行长期随访。结果:2组近期疗效相比,差异无统计学意义(P=0.159);2组的治疗有效率、疾病控制率、无进展生存期及总生存时间相比,差异均无统计学意义(P>0.05)。培美曲塞组Ⅲ、Ⅳ度白细胞减少、中性粒细胞减少、血小板减少、恶心呕吐的发生率均较多西他赛组下降(P<0.05)。结论:培美曲塞联合卡铂与多西他赛联合卡铂治疗吉非替尼耐药的晚期肺腺癌患者疗效相当,但培美曲塞联合卡铂方案的不良反应更轻,更值得临床推广。 | 亓妍文 LALLOO MBIBRAHIM 王丽萍 | 2020 | 郑州大学学报(医学版)2020，55，2： | 10 |
| 2 | Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs 显示文摘 | Lalloo U Fox A Belvisi M | 1995 | J Appl Physiol1995，79，4： | 1 |
| 3 | Life expectancy in hereditary cancer predisposing diseases:an observational study显示文摘 | Wilding A Ingham SL Lalloo F | | 0，，04： | 1 |
| 4 | Risks of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers显示文摘 | M Ahmed F Lalloo A Howell | 2010 | Breast Canc- er Research2010，12，1： | 1 |
| 5 | Non-operative management of haemobilia显示文摘 | Singh B Lalloo S | 2001 | Br J Surg2001，88，8： | 1 |
| 6 | Serological speciation of human schistosome infections by ELISA with a panel of three antigens显示文摘 | Turner P Lalloo K Bligh J | 2004 | Pathol2004，57，： | 1 |
| 7 | Occupational exposures and chronic obstructive pulmonary disease: a hospital based case - control study 显示文摘 | Govender N Lalloo UG Naidoo RN | 2011 | Thorax2011，66，7： | 1 |
| 8 | Budesonide and formoterol in a singer inhaler improves asthma control compared with increasing the dose of corticosteroid in adults with mild-to-moderate asthma显示文摘 | Lalloo UG Malolepszy J Kozma D | 2003 | Chest2003，123，： | 1 |
| 9 | Increased neutro- phils and cytokines, TNF - alpha and IL - 8, in induced sputum of non - asthmatic patients with chronic dry cough 显示文摘 | JATAKANON A LALLOO U G LIM S | 1999 | Thorax1999，54，3： | 1 |
| 10 | New Antituberculous Drugs in Development显示文摘 | Umesh G. Lalloo Anish Ambaram | 2010 | Current HIV / AIDS Reports2010，，3： | 1 |
| 11 | BRCA1,BRCA2 and TP53 mutations in very early-onset breast cancer with associated risks to relatives显示文摘 | Lalloo F Varley J Moran A | 2006 | Eur J Cancer2006，42，8： | 1 |
| 12 | Recent advances in the medical and surgical treatment of multi-drug resistant tuberculosis显示文摘 | Lalloo UG Naidoo R Ambaram A | 2006 | Curr Opin Pulm Med2006，12，3： | 1 |
| 13 | Case report: Abdominal cocoon associated with tuberculous pelvic inflammatory disease显示文摘 | Lalloo S Krishna D Maharajh J | 2002 | Br J Radiol2002，75，： | 1 |
| 14 | Endovascular treatment of very small intracranial aneurysms 显示文摘 | Ioannidis I Lalloo S Corkill R | 2010 | J Neurosurg2010，112，： | 1 |
| 15 | Management of venomous bites and stings in British Mihtary Personnel deployed in Iraq, Mghanistan and Cyprus显示文摘 | Lamb L Ross DA Lalloo DG | 2008 | J R Army Med Corps2008，154，4： | 1 |
| 16 | Increased neutrophils and cy- tokines,TNF-a and IL-8, in induced sputum of non-asthmatic pa- tients with chronic dry cough显示文摘 | Jatak anon A Lalloo UG Lim S | 1999 | Thorax1999，54，3： | 1 |
| 17 | Risk assessment and management of high risk familial breast cancer 显示文摘 | Evans DGR Lalloo F | 2002 | J Med Genet2002，39，12： | 1 |
| 18 | Low sensitivity of a nested polymerase chain reaction using in oropharyngeal washings for the diagnosis of pneumocystis pneumonia in HIV-infected patients显示文摘 | Nyamande K Lalloo VG York D | 2005 | Chest2005，128，： | 1 |
| 19 | Bradykinin-evoked sensitization of airway sensory nerves: a mecha- nism for ACE-inhibitor cough 显示文摘 | Fox AJ Lalloo UG Belvisi MG | 1996 | Nat Med1996，2，7： | 1 |
| 20 | A downstream process for production of a viable and stable Bacillus aquaculture biological agent显示文摘 | LALLOO R MAHARAJH D GORGENS J | 2010 | Appl Microbiol Biotechnol2010，86，2： | 1 |
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