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| 1 | Prognostic value of endothelial dysfunction in type 1 diabetes mellitus显示文摘Patients with diabetes mellitus are at high risk of developing atherosclerosis, associated with higher rates of micro and macro vascular involvement such as coronary artery disease and renal disease. The role of hyperglycemia to induce synthesis of reactive oxygen species by the oxidation of glucose, leading to an increased production of advanced glycosylation end products, as well as inflammation and oxidative stress has been proposed as a possible mechanism in the pathogenesis of endothelial dysfunction(ED). The interaction between C-peptide- the connecting segment of pro-insulin-and nitric oxide in vasodilation is also discussed. Therefore, endothelial dysfunction has been identified as an early marker of vascular disorder in type 1 and type 2 diabetes mellitus. In some other diseases, ED has been considered an independent predictor of vascular disease, regardless of the method used. Studies have demonstrated the importance of endothelial dysfunction as an useful tool for identifying the risk of vascular complications in patients with type 1 diabetes mellitus, particularly as regards to renal impairment. The aim of this review is to clarify the prognostic value of endothelial dysfunction as a marker of vascular disease in these subjects. | Ana Marice Ladeia Raphael Ribeiro Sampaio Maiara CostaHita Luis F Adan | 2014 | World Journal of Diabetes2014，5，5： | 2 |
| 2 | Non-pharmacological management of pediatric functional abdominal pain disorders:Current evidence and future perspectives显示文摘Functional abdominal pain disorders(FAPDs) are an important and prevalent cause of functional gastrointestinal disorders among children, encompassing the diagnoses of functional dyspepsia, irritable bowel syndrome, abdominal migraine, and the one not previously present in Rome Ⅲ, functional abdominal pain not otherwise specified. In the absence of sufficiently effective and safe pharmacological treatments for this public problem, non-pharmacological therapies emerge as a viable means of treating these patients, avoiding not only possible side effects, but also unnecessary prescription, since many of the pharmacological treatments prescribed do not have good efficacy when compared to placebo. Thus, the present study provides a review of current and relevant evidence on non-pharmacological management of FAPDs, covering the most commonly indicated treatments, from cognitive behavioral therapy to meditation, acupuncture, yoga, massage, spinal manipulation, moxibustion, and physical activities. In addition, this article also analyzes the quality of publications in the area, assessing whether it is possible to state if non-pharmacological therapies are viable, safe, and sufficiently well-based for an appropriate and effective prescription of these treatments. Finally, it is possible to observe an increase not only in the number of publications on the non-pharmacological treatments for FAPDs in recent years, but also an increase in the quality of these publications. Finally, the sample selection of satisfactory age groups in these studies enables the formulation of specific guidelines for this age group, thus avoiding the need for adaptation of prescriptions initially made for adults, but for children use. | Maria Luísa Cordeiro Santos Ronaldo Teixeira da Silva Júnior Breno Bittencourt de Brito Filipe Antônio França da Silva Hanna Santos Marques Vinícius Lima de SouzaGonçalves Talita Costa dos Santos Carolina Ladeia Cirne Natália Oliveira e Silva Márcio Vasconcelos Oliveira Fabrício Freire de Melo | 2022 | World Journal of Clinical Pediatrics2022，11，2： | 2 |
| 3 | Testicular myeloid sarcoma : case report 显示文摘 | Zago LB Ladeia AA Etchebehere RM | 2013 | Rev Bras Hematol Hemoter2013，35，1： | 1 |
| 4 | Studies of Gene Variants Related to Inflammation, Oxidative Stress, Dyslipidemia, and Obesity: Implications for a Nutrigenetic Approach显示文摘 | Maira Ladeia R. Curti Patrícia Jacob Maria Carolina Borges Marcelo Macedo Rogero Sandra Roberta G. Ferreira Jordi Salas Salvado | 2011 | Journal of Obesity2011，，： | 1 |
| 5 | A palm oil - rich diet may reduce serum lipids in healthy young individuals显示文摘 | Ladeia A M Costa- Matos E Barata - Passos R | 2008 | Nutrition2008，24，1： | 1 |
| 6 | Endothelial dysfunction is correlated with microalbuminuria in children with shortduration type 1 diabetes 显示文摘 | Ladeia AM Ladeia-Frota C Pinho L | 2005 | Diabetes Care2005，28，： | 1 |
| 7 | Risk of coronary graft disease following heart transplantation显示文摘 | Le Bidois J Ladeia A Vouhe P | 1993 | Noppon Kyobu Gakkai Zasshi1993，42，10： | 1 |
| 8 | Testicular myeloid sarcoma: case report显示文摘 | Zago LB Ladeia AA Etchebehere RM | 2013 | Rev Bras Hematol Hemoter2013，35，1： | 1 |
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