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| 1 | Suppression of Jasmonic Acid-Mediated Defense by Viral-Inducible MicroRNA319 Facilitates Virus Infection in Rice显示文摘MicroRNAs (miRNAs ) 是植物开发和主人病毒相互作用的枢轴的调节的人。然而,角色和涉及病毒的感染和主人危险性的特定的 miRNAs 的行动模式仍然保持大部分不清楚。在这研究,我们给那瑞斯看引起 miR319 的增加的累积,但是减少的破旧绝技病毒(RRSV ) 感染调整 miR319 的 TCP (TEOSINTE BRANCHED/CYCLOIDEA/PCF ) 的表示基因,特别 TCP21,在米饭植物。转基因的米饭植物 overexpressing miR319 或 downregulating TCP21 展出了像疾病的显型并且与野类型的植物比较显示出显著地更高的危险性到 RRSV。相反,仅仅温和的疾病症状在感染 RRSV 的线 overexpressing TCP21 并且特别在转基因的植物 overexpressing 被观察 miR319 抵抗的 TCP21。miR319 的 RRSV 感染和 overexpression 在米饭与 JA 生合成和信号相关的基因的 downregulated 表示一起引起了减少的内长的 jasmonic 酸(JA ) 层次。然而,有甲基 jasmonate 的米饭植物的治疗减轻了 RRSV 引起并且减少了病毒累积的疾病症状。一起拿,我们的结果建议由在米饭的 RRSV 感染的 miR319 的正式就职压制调停 JA 的防卫便于病毒感染和症状开发。 | Chao Zhang Zuomei Ding Kangcheng Wu Liang Yang Yang Li Zhen Yang Shan Shi Xiaojuan Liu Shanshan Zhao Zhirui Yang Yu Wang Luping Zheng Juan Wei Zhenguo Du Aihong Zhang Hongqin Miao Yi Li Zujian Wu Jianguo Wu | 2016 | Molecular Plant2016,9,9: | 27 |
| 2 | Control of Deep Tectonics on the Superlarge Deposits in China显示文摘Seventy-three large-superlarge deposits in China were formed in 4 metallogenic epochs, and located in 6metallogenic domains. By combing their time-space distribution and the relevant data of crustal thickness, we discuss the control conditions of deep tectonics on superlarge deposits. The various spatial variation of the crustal thickness where deposits locate is closely related to their different tectonic setting. The crustal thickness of the region where deposits are in the Precambrian metallogenic epoch is 37.1 km and shows double-peak distribution, which is related to the different tectonic-mineralization processes in the Tarim-North China and Yangtze metallogenic domains. The crustal thickness of the region where deposits are in the Paleoproterozoic metallogenic epoch is 43.4 km and shows normal distribution, which is the result of 'pure' mineralization setting. The crustal thickness of the region where deposits are in the Late PalaeozoicEarly Mesozoic metallogenic epoch is about 41.2 km and shows multi-peak distribution, which can be related with dispersing distribution in the metallogenic domain of these superlarge deposits. The crustal thickness of the region where deposits are in the post-Indosinian metallogenic epoch is 37.3 km, and shows skew distribution, which resulted from different tectonic settings in eastern and western China. | YANGLiqiang DENGJun WANGJianguo WEIYanguang WANGJianping WANGQinfei LUPing | 2004 | Acta Geologica Sinica(English Edition)2004,78,2: | 26 |
| 3 | Curculigoside isolated from Curculigo orchioides prevents hydrogen peroxide-induced dysfunction and oxidative damage in calvarial osteoblasts显示文摘反应的氧种类(ROS ) 包括 H2O2,在骨质疏松症的 pathophysiology 起一个关键作用。因此,能禁止 ROS 生产的代理人或抗氧化剂在骨质疏松症的治疗有高临床的价值。Curculigoside (杂种狗) ,酉分的混合物从 Curculigo orchioides Gaertn 的根茎孤立的主要 bioactive 之一,被报导有有势力抗氧化剂和 anti-osteoporotic 性质。然而,没有直接证据与观察 anti-osteoporotic 效果连接杂种狗的抗氧化剂能力,并且相关分子的机制仍然保持不清楚。因此,我们在 calvarial 造骨细胞对氧化应力调查了杂种狗的保护的效果并且讨论了相关机制。造骨细胞生存能力在 48-h 暴露以后显著地减少了到 H2O2 的 400 M,这被发现,与对待车辆的房间相比,并且 H2O2 的细胞毒素的效果显著地被颠倒什么时候有杂种狗的 0.110 M 的 pretreated (P < 0.05 ) 。有杂种狗的 0.110 M 的预告的处理减少了 ROS 生产和类脂化合物 peroxidation,并且增加了抗氧化剂酶的活动,例如 superoxide,在造骨细胞的 dismutase 和谷胱甘肽 peroxidase 由 H2O2 导致了。另外,象碱的磷酸酶,钙免职,和 Runx2 水平那样的区别标记的导致 H2O2 的减小显著地面对杂种狗被恢复。杂种狗也颠倒了细胞外的调整信号的 kinase 1/2,并且原子 factor-B 发信号和 p38 的抑制的导致 H2O2 的刺激激活 mitogen 的蛋白质 kinase 激活。这些结果通过减少 ROS 的生产提供新卓见进杂种狗的造骨细胞保护的机制,建议那条杂种狗可以作为为骨质疏松症和另外的骨头相关的人的疾病的预防和处理的一个对简历安全的代理人被开发。 | Ying Wang Lu Zhao Yin Wang Jinlong Xu Yah Nie Yuanhui Guo Yongtao Tong Luping Qin Qiaoyan Zhang | 2012 | Acta Biochimica et Biophysica Sinica2012,44,5: | 15 |
| 4 | Thin-bed thickness calculation formula and its approximation using peak frequency显示文摘在调节厚度下面的量的厚度评价是在地震探索的大挑战。的大多数研究焦点薄床系数相等的大小和相反的极性是其顶和底部思考。另外的薄床的类型上没有系统的研究。在这篇文章,所有薄床被分类进四种类型:与不相等的大小和相同极性与相等的大小和相反的极性薄床、与不相等的大小和相反的极性薄床、与相等的大小和相同极性薄床、薄床。由分析学习,描述在地震山峰频率和薄床的厚度之间的一般关系的一个方程被导出它在那里的表演并且哪个是在他们之间的一种复杂含蓄的非线性的关系是困难的在实践使用。以便解决这个问题,我们由泰勒扩大简化关系并且为四种类型与不同订单讨论近似公式的精确薄床。与为薄床的厚度计算的传统的振幅方法相比,方法我们在场有更高的精确并且没被顶或底部思考系数的绝对值影响,它因此对在实践的使用方便。 | Sun Luping Zheng Xiaodong Li Jingsong Shou Hao | 2009 | Applied Geophysics2009,6,3: | 13 |
| 5 | Effects of lysedEnterococcus faecalis FK-23 on experimental allergic rhinitis in a murine model显示文摘In the current study,we sought to investigate whether lysed Enterococcus faecalis FK-23(LFK),a heat-killed probiotic preparation,attenuated eosinophil influx into the upper airway and had immunomodulatory activity in a murine allergic rhinitis model.Eighteen BALB/c mice were divided into three groups;the ovalbumin(OVA)-sensitized/challenged group,which received saline orally for 6 weeks(OVA group),the OVA-sensitized/challenged group,which received LFK orally for 6 weeks(LFK-fed group),and the non-sensitized group,which received saline for 6 weeks(saline control group).Nasal rubbing and sneezing were monitored during the study.After the final challenge,interleukin(IL)-4,interferon(IFN)-γ,and OVA-specific IgE levels in the sera and splenocyte culture supernatants were determined,eosinophilic infiltrate into the upper airway was quantified,and splenic CD4+CD25+ regulatory T cells(Tregs) were examined by flow cytometry.We found that nasal rubbing was significantly reduced in LFK-fed mice compared to the OVA group on d 27 and 35,and sneezing was significantly inhibited by LFK administration for 35 d.LFK-fed mice had significantly less eosinophil influx into the nasal mucosa than the OVA group.There were no significant differences between the LFK-fed group and OVA group in the serum and splenocyte culture supernatant levels of IL-4,IFN-γ,and OVA-specific IgE.Interestingly,the LFK-fed mice had a significantly greater percentage of splenic CD4+CD25+ Tregs than OVA group.Our results indicate that oral administration of LFK may alleviate nasal symptoms,reduce nasal eosinophilia,and increase the percentage of CD4+CD25+ Tregs in experimental allergic rhinitis. | Luping Zhu Takashi Shimada Ruoxi Chen Meiping Lu Qingzhao Zhang Wenmin Lu Min Yin Tadao Enomoto Lei Cheng | 2012 | The Journal of Biomedical Research2012,26,3: | 11 |
| 6 | An improved phase measurement method of integrated pulse profile for pulsar显示文摘Integrated profile is one of the basic characteristic of X-ray pulsar.Gaussian function fit is used to model the components of X-ray pulsar profile,and it is combined with Poisson distribution model of X-ray pulsar to analyze Cramér-Rao low bound (CRLB) of phase,phase rate estimation and relation between CRLB and profile components.Then,a time domain method us-ing minimum entropy is proposed for profile phase and phase rate estimation,and its effectiveness is explained using simula-tion examples. | ZHANG Hua XU LuPing | 2011 | Science China(Technological Sciences)2011,54,9: | 10 |
| 7 | Early-onset colorectal cancer:A sporadic or inherited disease?显示文摘Colorectal cancer is the third most common cancer diagnosed worldwide.Although epidemiology data show a marked variability around the world,its overall incidence rate shows a slow but steady decrease,mainly in developed countries.Conversely,early-onset colorectal cancer appears to display an opposite trend with an overall prevalence in United States and European Union ranging from 3.0% and 8.6%.Colorectal cancer has a substantial proportion of familial cases.In particular,early age at onset is especially suggestive of hereditary predisposition.The clinicopathological and molecular features of colorectal cancer cases show a marked heterogeneity not only between early- and late-onset cases but also within the early-onset group.Two distinct subtypes of early-onset colorectal cancers can be identified:a 'sporadic' subtype,usually without family history,and an inherited subtype arising in the context of well defined hereditary syndromes.The pathogenesis of the early-onset disease is substantially well characterized in the inherited subtype,which is mainly associated to the Lynch syndrome and occasionally to other rare mendelian diseases,whereas in the 'sporadic' subtype the origin of the disease may be attributed to the presence of various common/rare genetic variants,so far largely unidentified,displaying variable penetrance.These variants are thought to act cumulatively to increase the risk of colorectal cancer,and presumably to also anticipate its onset.Efforts are ongoing in the attempt to unravel the intricate genetic basis of this 'sporadic' early-onset disease.A better knowledge of molecular entities and pathways may impact on family-tailored prevention and clinical management strategies. | Vittoria Stigliano Lupe Sanchez-Mete Aline Martayan Marcello Anti | 2014 | World Journal of Gastroenterology2014,20,35: | 10 |
| 8 | 钢筋混凝土结构的耐久性和服役寿命预测(英文)显示文摘介绍了钢筋混凝土结构在氯离子渗透、碳化和冻融侵蚀作用下的耐久性和服役寿命预测模型。过去几年有关组织或国际学术委员会提出了大量的混凝土结构耐久性设计模型。为了在混凝土结构耐久性设计过程中,能够安全地使用此类模型,需要通过分析和比较长期暴露在不同气候条件下的混凝土劣化现场数据,对预测模型的可用性进行验证。在本文中,对混凝土抗氯离子渗透、碳化和冻融侵蚀的各种模型进行了简要阐述。通过暴露时间超过20年的露天场数据,以及约使用了30年的公路桥的现场数据,对包括简单ERFC模型、DuraCrete模型和ClinConc模型在内的3种氯离子渗透模型进行了评估。同时,使用暴露11年的露天场所的现场数据和7~13年的现有建筑的有限数据对一种预测混凝土碳化深度的物理化学模型进行了评价。针对冻融侵蚀的模型,讨论了临界饱和度测量和实际的饱和度测量中的一些问题。根据对结果的比较,可以发现在大多数情况下,简单ERFC模型在大多数情况下对氯离子渗透的预测值高于实际值,而DuraCrete模型的预测值偏低。另外,ClinConc模型对短期f1年)和长期(21年)暴露条件下的预测更合理,预测效果更好。与在挪威获得的暴露级别为XC3现场数据比较,发现Papadakis碳化模型可以较好地预测碳化深度;但是,与暴露级别为XC4级的现场数据比较发现,该模型低估了碳化深度。 | Luping TANG Peter UTGENANNT Dimitrios BOUBITSAS | 2015 | 硅酸盐学报2015,43,10: | 10 |
| 9 | Modeling and Doppler measurement of X-ray pulsar显示文摘Generally,the Doppler caused by the velocity of the detector leads to distortion of the integrated profile of the X-ray pulsar,on the contrary,if the distortion can be used to measure the Doppler,then the velocity of the detector is easy to be solved.In view of this,the correlation of the periodic error arise from the Doppler and the integrated profile was analyzed,then,based on the Poisson distribution model of the X-ray Pulsar,a new signal model and the concept of the profile entropy was defined.Furthermore,the directly cumulated profile of the signal was modeled with the Doppler as a parameter,and then the Doppler was solved via optimal method.Simultaneously,the performance of phase measurement based on this method was studded.The analysis shows that this method can get rid of the periodic error due to the discrete sampling,and can obtain continuous phase estimation.The experiment verification shows the consistency of the theory and the experiment. | ZHANG Hua | 2011 | Science China(Physics,Mechanics & Astronomy)2011,54,6: | 10 |
| 10 | 晚期非小细胞肺癌免疫检查点抑制剂新型生物标志物:血液PD-L1动态检测显示文摘背景免疫检查点抑制剂(immune checkpoint inhibitors,ICIs)具有良好疗效已成为恶性肿瘤治疗领域备受瞩目的翘楚。然而,仅有小部分患者获得长期临床获益。如何选择生物标志物来筛查ICIs治疗优势人群仍是一大热点。方法收集51例晚期恶性肿瘤患者的肿瘤组织和配对血样本,进行PD-L1表达的相关性分析。40例晚期非小细胞肺癌(non-small cell lung cancer,NSCLC)患者接受ICIs治疗,2个月时检测血液PD-L1(bloodPD-L1,bPD-L1)表达的动态变化,包括PD-L1 mRNA、外泌体PD-L1(exosomalPD-L1,exoPD-L1)蛋白和可溶性PD-L1(solublePD-L1,sPD-L1)。应用R软件计算最佳截断值,用于预测最佳客观缓解(best objective response,b OR)、无进展生存期(progression-free survival,PFS)和总生存期(overall survival,OS)。结果51例不同恶性肿瘤患者中,组织PD-L1(tissuePD-L1,tPD-L1)表达阳性患者的PD-L1mRNA表达水平显著升高。40例接受ICIs治疗的晚期NSCLC患者中,bPD-L1 mRNA上调≥2.04的患者b OR、PFS和OS更佳;21例接受ICIs治疗的晚期NSCLC患者中,exoPD-L1上调≥1.86的患者临床获益更大。sPD-L1动态变化与ICIs疗效无显著相关性。PD-L1 mRNA和exoPD-L1联合检测更有利于预测ICIs治疗疗效。结论bPD-L1表达与tPD-L1表达存在正相关;晚期NSCLC患者ICIs治疗初期PD-L1 mRNA和(或)exoPD-L1表达升高,可作为评估临床获益的新型生物标志物。 | Qiao YANG Mingjing CHEN Jiaoyang GU Kai NIU Xianlan ZHAO Linpeng ZHENG Zihan XU Yongxin YU Feng LI Lingxin MENG Zhengtang CHEN Wenlei ZHUO Luping ZHANG Jianguo SUN 杨峤(译) 孙建国(译) | 2021 | 中国肺癌杂志2021,24,12: | 10 |
| 11 | Fast structured illumination microscopy via deep learning显示文摘This study shows that convolutional neural networks(CNNs)can be used to improve the performance of structured illumination microscopy to enable it to reconstruct a super-resolution image using three instead of nine raw frames,which is the standard number of frames required to this end.Owing to the isotropy of the fluorescence group,the correlation between the high-frequency information in each direction of the spectrum is obtained by training the CNNs.A high-precision super-resolution image can thus be reconstructed using accurate data from three image frames in one direction.This allows for gentler super-resolution imaging at higher speeds and weakens phototoxicity in the imaging process. | CHANG LING CHONGLEI ZHANG MINGQUN WANG FANFEI MENG LUPING DU XIAOCONG YUAN | 2020 | Photonics Research2020,8,8: | 8 |
| 12 | Current status of cell-mediated regenerative therapies for human spinal cord injury显示文摘During the past decade, significant advances have been made in refinements for regenerative therapies following human spinal cord injury(SCI).Positive results have been achieved with different types of cells in various clinical studies of SCI.In this review, we summarize recently-completed clinical trials using cellmediated regenerative therapies for human SCI, together with ongoing trials using neural stem cells.Specifically, clinical studies published in Chinese journals are included.These studies show that current transplantation therapies are relatively safe, and have provided varying degrees of neurological recovery.However, many obstacles exist, hindering the introduction of a specifi c clinical therapy, including complications and their causes, selection of the target population, and optimization of transplantation material.Despite these and other challenges, with the collaboration of research groups and strong support from various organizations, cell-mediated regenerative therapies will open new perspectives for SCI treatment. | Tongming Zhu Qisheng Tang Huasong Gao Yiwen Shen Luping Chen Jianhong Zhu | 2014 | Neuroscience Bulletin2014,30,4: | 7 |
| 13 | Ultra-broadband on-chip twisted light emitter for optical communications显示文摘On-chip twisted light emitters are essential components of orbital angular momentum(OAM)communication devices1,2.These devices address the growing demand for high-capacity communication systems by providing an additional degree of freedom for wavelength/frequency division multiplexing(WDM/FDM).Although whispering-gallery-mode-enabled OAM emitters have been shown to possess some advantages3–5,such as compactness and phase accuracy,their inherent narrow bandwidths prevent them from being compatible with WDM/FDM techniques.Here,we demonstrate an ultra-broadband multiplexed OAM emitter that utilizes a novel joint path-resonance phase control concept.The emitter has a micron-sized radius and nanometer-sized features.Coaxial OAM beams are emitted across the entire telecommunication band from 1,450 to 1,650 nm.We applied the emitter to an OAM communication with a data rate of 1.2 Tbit/s assisted by 30-channel optical frequency combs(OFCs).The emitter provides a new solution to further increase capacity in the OFC communication scenario. | Zhenwei Xie Ting Lei Fan Li Haodong Qiu Zecen Zhang Hong Wang Changjun Min Luping Du Zhaohui Li Xiaocong Yuan | 2018 | Light(Science & Applications)2018,7,1: | 7 |
| 14 | Dog sciatic nerve gap repaired by artificial tissue nerve graft显示文摘The feasibility of repairing dog sciatic nerve damage by using a biodegradable artificial tissue nerve graft enriched with neuroregenerating factors is investigated. The artificial nerve graft was implanted to a 30 mm gap of the sciatic nerve damage in 7 dogs. The dogs with the same nerve damage that were repaired by interposition of the autologous nerve or were given no treatment served as control group 1 or 2, respectively. The observations include gross and morphological observations, immune reaction, electrophysiological examination, fluorescence tracing of the neuron formation and the number of the neurons at the experimental sites, etc. Results showed that 6 months after the implantation of the graft, the regenerated nerve repaired the damage of the sciatic nerve without occurrence of rejection and obvious inflammatory reaction in all 7 dogs, and the function of the sciatic nerve recovered with the nerve conduction velocity of (23.91±11.35)m/s. The regenerated neurons and the forming of axon could be observed under an electron microscope. This proves that artificial tissue nerve graft transplantation can bridge the damaged nerve ends and promote the nerve regeneration. | GU Xiaosong, ZHANG Peiyun, WANG Xiaodong, DING Fei, PENG Luping and CHENG Hongbing(Nantong Medical College, The Key Laboratory of Neuroregeneration of Jiangsu Province, Nantong 226001, China) | 2003 | Progress in Natural Science:Materials International2003,13,8: | 6 |
| 15 | DCT domain filtering method for multi-antenna code acquisition显示文摘For global navigation satellite system(GNSS) signals in Gaussian and Rayleigh fading channel, a novel signal detection algorithm is proposed. Under the low frequency uncertainty case, after performing discrete cosine transform(DCT) to the outputs of the partial matched filter(PMF) for every antenna, the high order components in the transforming domain will be filtered, then the equalgain(EG) combination for the inverse discrete cosine transform(IDCT) reconstructed signal would be done subsequently. Thus,due to the different frequency distribution characteristics between the noise and signals, after EG combination, the energy of signals has almost no loss and the noise energy is greatly reduced. The theoretical analysis and simulation results show that the detection algorithm can effectively improve the signal-to-noise ratio of the captured signal and increase the probability of detection under the same false alarm probability. In addition, it should be pointed out that this method can also be applied to Rayleigh fading channels with moving antenna. | Xiaojie Li Luping Xu Shibin Song Hua Zhang | 2013 | Journal of Systems Engineering and Electronics2013,24,5: | 6 |
| 16 | Growth and wood properties of a 38-year-old Populus simonii 3 P.nigra plantation established with different densities in semi-arid areas of northeastern China显示文摘To characterize the effects of plantation densities on the growth characteristics(diameter at breast level,tree height and volume)and the common wood properties,38-year-old Populus simonii 9 P.nigra clones planted with four levels of spacing(2 m 92 m,3 m 93 m,4 m 94 m,and 5 m 95 m)in a semi-arid area in northeastern China were examined.The results of ANOVA showed significant differences(P\0.01)for all the investigated growth traits and wood properties under different plantation densities,except for the chemical composition of wood.The repeatability and phenotypic variations of all the traits varied from 0.34 to 0.99 and from 13.45 to 59.65%,respectively.Except for wood density,which was significantly negatively correlated with the growth traits,a positive correlation was observed between the growth traits and all the other wood mechanical properties.However,most of the correlations between the growth traits and the chemical composition of the wood were not significant.The path analysis for the wood mechanical characteristics and the growth in the prediction of volume were significant and ranged from 0.18 to 0.72 for wood density and diameter at breast height,respectively,while those for the chemical composition of wood ranged from 0.001 to 0.336,which showed a low impact on the volume.The highest stand volume(610 m3)per hectare was observed with the 2 m 92 m spacing,which consequently provided a high total price and income,while a high individual volume growth per tree was observed with the 5 m 95 m spacing.The results suggested that for the poplar trees younger than 40 years in a semi-arid area in China,2 m 92 m spacing is suitable for obtaining a high volume per hectare,while 5 m 95 m spacing is best for obtaining a high individual volume per tree. | Ammar Khalil Mohamed Ahmed Zhixiang Fu Changjun Ding Luping Jiang Xidong Han Aiguo Yang Yinghui Ma Xiyang Zhao | 2020 | Journal of Forestry Research2020,31,2: | 6 |
| 17 | Changes in brain activation in stroke patients after mental practice and physical exercise: a functional MRI study显示文摘Mental practice is a new rehabilitation method that refers to the mental rehearsal of motor imagery content with the goal of improving motor performance.However,the relationship between activated regions and motor recovery after mental practice training is not well understood.In this study,15 patients who suffered a first-ever subcortical stroke with neurological deficits affecting the right hand,but no significant cognitive impairment were recruited.10 patients underwent mental practice combined with physical practice training,and 5 patients only underwent physical practice training.We observed brain activation regions after 4 weeks of training,and explored the correlation of activation changes with functional recovery of the affected hands.The results showed that,after 4 weeks of mental practice combined with physical training,the Fugl-Meyer assessment score for the affected right hand was significantly increased than that after 4 weeks of practice training alone.Functional MRI showed enhanced activation in the left primary somatosensory cortex,attenuated activation intensity in the right primary motor cortex,and enhanced right cerebellar activation observed during the motor imagery task using the affected right hand after mental practice training.The changes in brain cortical activity were related to functional recovery of the hand.Experimental findings indicate that cortical and cerebellar functional reorganization following mental practice contributed to the improvement of hand function. | Hua Liu Luping Song Tong Zhang | 2014 | Neural Regeneration Research2014,9,15: | 5 |
| 18 | Emergy-based sustainability assessment of Inner Mongolia显示文摘内部蒙古自治区域(IMAR ) 的综合环境财务从 1987 ~ 2007 与数据基于 emergy 分析在这份报纸被介绍。通过精明的环境、经济的输入和一系列 emergy 指示物,这份报纸讨论 IMAR 资源使用结构,经济状况,和贸易地位。结果证明在 IMAR 使用的超过 85% emergy 从家来源被导出,显示为自足的一个强壮的能力。集中使用的本地非可更新的 emergy,向 IMAR 经济提供大多数驱动力,在 2004 以后在全部的 emergy 使用拿了最大的份额并且在 2007 到达了 58% 。2000 的西方的中国发展计划从 IMAR 迎来了煤和电生产和出口的快速的生长到中国的另外的区域。IMAR 的出口 / 进口 emergy 比率在 2007 到达了 3.46,与出口的煤(3.44 ? 楤敶獲瑩 ? 湡 ? 灳瑡慩? 慰瑴牥 ? 景攠潣祳瑳浥猠牴 ' 壮肭勉硴秤硿爆崫?眠楨档椠 ? 桴 ? 慭湩 ' 獪珷箾 K 映捡潴 ? 湯瘠来瑥瑡潩 ? 慬摮 ' 諡?楤敶獲瑩 ? 湡 ? 灳瑡慩? 楤瑳楲畢楴湯漠 ?题传 | ZHU Luping LI Haitao CHEN Jiquan JOHN Ranjeet LIANG Tao YAN Maochao | 2012 | Journal of Geographical Sciences2012,22,5: | 5 |
| 19 | Discrimination of False Negative Results in RT-PCR Detection of SARS-CoV-2 RNAs in Clinical Specimens by Using an Internal Reference显示文摘Reverse transcription-polymerase chain reaction(RT-PCR)is an essential method for specific diagnosis of SARS-CoV-2 infection.Unfortunately,false negative test results are often reported.In this study,we attempted to determine the principal causes leading to false negative results of RT-PCR detection of SARS-CoV-2 RNAs in respiratory tract specimens.Multiple sputum and throat swab specimens from 161 confirmed COVID-19 patients were tested with a commercialfluorescent RT-PCR kit targeting the ORF1 ab and N regions of SARS-CoV-2 genome.The RNA level of a cellular housekeeping gene ribonuclease P/MRP subunit p30(RPP30)in these specimens was also assessed by RT-PCR.Data for a total of 1052 samples were retrospectively re-analyzed and a strong association between positive results in SARS-CoV-2 RNA tests and high level of RPP30 RNA in respiratory tract specimens was revealed.By using the ROC-AUC analysis,we identified Ct cutoff values for RPP30 RT-PCR which predicted false negative results for SARS-CoV-2 RT-PCR with high sensitivity(95.03%–95.26%)and specificity(83.72%–98.55%)for respective combination of specimen type and ampli-fication reaction.Using these Ct cutoff values,false negative results could be reliably identified.Therefore,the presence of cellular materials,likely infected host cells,are essential for correct SARS-CoV-2 RNA detection by RT-PCR in patient specimens.RPP30 could serve as an indicator for cellular content,or a surrogate indicator for specimen quality.In addition,our results demonstrated that false negativity accounted for a vast majority of contradicting results in SARS-CoV-2 RNA test by RT-PCR. | Yafei Zhang Changtai Wang Mingfeng Han Jun Ye Yong Gao Zhongping Liu Tengfei He Tuantuan Li Mengyuan Xu Luping Zhou Guizhou Zou Mengji Lu Zhenhua Zhang | 2020 | Virologica Sinica2020,35,6: | 5 |
| 20 | Synthesis of nitrogen-doped carbon nanotubes-FePO_4 composite from phosphate residue and its application as effective Fenton-like catalyst for dye degradation显示文摘Phosphate residue is regarded as a hazardous waste, which could potentially create significant environmental and health problems if it is not properly treated and disposed of. In this study, nitrogen-doped carbon nanotubes-FePO_4(NCNTs-FePO_4) composite was successfully synthesized from phosphate residue, and its application as an effective catalyst was explored. Firstly, an effective method was developed to recover FePO_4 from phosphate residue, achieving an impressive FePO_4 mass recovery rate of 98.14%. Then, the NCNTsFePO_4 catalyst was synthesized from the recovered FePO_4 by two main reactions, including surface modification and chemical vapor deposition. Finally, the synthesized NCNTs-FePO_4 was applied to photo-degrade 15 mg/L Rhodamine B(RhB) in a Fenton-like system. The results showed that 98.9% of RhB could be degraded in 60 min, closely following the pseudofirst-order kinetics model. It was found that even after six consecutive cycles, NCNTs-FePO_4 still retained a high catalytic capacity(>50%). Moreover, ·OH radicals participating in the RhB degradation process were evidenced using quenching experiments and electron paramagnetic resonance analysis, and a rational mechanism was proposed. It was demonstrated that the materials synthesized from hazardous phosphate residue can be used as an effective catalyst for dye removal. | Lianmei Wei Yi Zhang Shengwen Chen Luping Zhu Xiaoyu Liu Lingxue Kong Lijun Wang | 2019 | Journal of Environmental Sciences2019,31,2: | 4 |