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| 1 | A Novel QTL qTGW3 Encodes the GSK3/ SHAGGY-Like Kinase OsGSK5/OsSK41 that Interacts with OsARF4 to Negatively Regulate Grain Size and Weight in Rice显示文摘谷物尺寸和形状在米饭是谷物重量和产量的重要决定因素。这里,我们报导一个新主要量的特点在米饭的地点(QTL ) , qTGW3,那种控制谷物尺寸和重量。这个地点, qTGW3,编码 OsSK41 (也作为 OsGSK5 知道) , GLYCOGEN SYNTHASE KINASE 3/SHAGGY-like 家庭的一个成员。带 OsSK41 的 loss-of-function 等位基因的瑞斯 near-isogenic 线增加了谷物长度和重量。我们证明那 OsSK41 交往与并且 phosphorylates 植物生长素反应因素 4 (OsARF4 ) 。有 OsARF4 的 OsSK41 的合作表示在米饭原物增加 OsARF4 的累积。OsARF4 的功能的损失导致更大的米饭谷物。定序 RNA 分析建议 OsARF4 和 OsSK41 镇压下游的基因的一个普通集合的表示, ? 包括一些植物生长素应答的基因,在米饭谷物开发期间。在 qTGW3 的 OsSK41 的 loss-of-function 形式代表没被指向的基因编辑或 QTL 节节上升广泛地在 OsSK41 功能的米饭 breeding.?Suppression 利用了的稀罕等位基因提高米饭谷物尺寸和重量。因此,我们的学习在米饭谷物开发揭示 OsSK41 的重要角色 ?? 并且在另外的谷物庄稼在米饭并且也许为谷物产量的基因改进提供新候选人基因。 | Zejun Hu Sun-Jie Lu Mei-Jing Wang Haohua He Le Sun Hongru Wang Xue-Huan Liu Ling Jiang Jing-Liang sun Xiaoyun Xin Wei Kong Chengcai Chu Hong-Wei Xue Jinshui Yang Xiaojin Luo Jian-Xiang Liu | 2018 | Molecular Plant2018，11，5： | 47 |
| 2 | Prevalence of high-risk human papillomavirus infection in different cervical lesion among organized health-examination women in Shanghai, China显示文摘背景颈的癌症是从在 worldwide.Human 乳头状瘤病毒( HPV )演的女人之中的癌症的死亡的第二个很普通的原因在颈的 cancer.It 的病原学的一个中央角色是重要的在颈的损害的不同类型描述 HPV 感染的流行并且探索在 HPV 病毒的负担之间的关系并且颈的 lesions.Methods 到的严厉在不同年龄组描述 HPV 感染流行和病毒的负担,我们回顾地调查了女人 w 的 6405 | ZHANG Wen-ying XUE Yue-zhen CHEN Min HAN Ling LUO Man | 2008 | Chinese Medical Journal2008，，16： | 31 |
| 3 | Mutation analysis of APC gene in gastric cancer with microsatellite instability显示文摘AIM: To evaluate the role of APC mutation in gastric carcinogenesis and to correlate APC mutation with microsatellite instability (MSI) in gastric carcinomas. METHODS: APC mutation was measured with multiplex PCR, denaturing gradient gel electrophoresis and DNA sequencing; and MSI was analyzed by PCR-based methods.RESULTS: Sixty-eight cases of sporadic gastric carcinoma were studied for APC mutation at exon 15 and MSI. APC mutaions were detected in 15(22.1%) gastric cancers. Frequence of APC mutation (33.3 %) in intestinal type of gastric cancer was significantly higher than that in diffuse type (13.1 %, P<0.05).On the contrary, no association was observed betweerAPC mutation and tumor size,differentiation, depth of invasion, metastasis or clinical stages.Using five microsatellite markers, MSI in at least one locus was detected in 17 of 68 (25 %) of the tumors analyzed.APC mutations were all detected in MSI-L (only one locus,n=9) or MSS(tumor lacking MSI or stable, n=51), but no mutation was found in MSI-H (≥2 loci, n=8).CONCLUSION: APC mutation is involved in carcinogenesis of intestinal type of gastric cancer and is independent of MSI phenotype but related to the LOH pathway in gastric cancer. | Dian-Chun Fang Yuan-Hui Luo Shi-Ming Yang Xiao-An Li Xian-Long Ling Li Fang Department of Gastroenterology,Southwest Hospital,Third Military Medical University,Chongqing 400038,China | 2002 | World Journal of Gastroenterology2002，8，5： | 34 |
| 4 | PVT v2:Improved baselines with Pyramid Vision Transformer显示文摘Transformers have recently lead to encouraging progress in computer vision.In this work,we present new baselines by improving the original Pyramid Vision Transformer(PVT v1)by adding three designs:(i)a linear complexity attention layer,(ii)an overlapping patch embedding,and(iii)a convolutional feed-forward network.With these modifications,PVT v2 reduces the computational complexity of PVT v1 to linearity and provides significant improvements on fundamental vision tasks such as classification,detection,and segmentation.In particular,PVT v2 achieves comparable or better performance than recent work such as the Swin transformer.We hope this work will facilitate state-ofthe-art transformer research in computer vision.Code is available at http://gffzz188fe103f8f1460asc5w99q90nbfo6pkw.ffgz.tsg.suse.edu.cn/whai362/PVT. | Wenhai Wang Enze Xie Xiang Li Deng-Ping Fan Kaitao Song Ding Liang Tong Lu Ping Luo Ling Shao | 2022 | Computational Visual Media2022，8，3： | 30 |
| 5 | Totally percutaneous thoracic endovascular aortic repair with the preclosing technique: a case-control study显示文摘背景常规胸的 endovascular 大动脉的修理(TEVAR ) 在一般或硬膜上的麻醉下面包含腹股沟切口。作为向更少的侵略过程的技术行动,一条全部的经皮的途径是 desirable.In 这研究,我们描述一种 Preclosing 技术并且为大腿骨的存取地点管理调查它的安全和功效,并且当与那些相比传统的外科的缩小的 approaches.Methods Preclosing 技术包含二,评估它的优点或多重在 upsizing 前在大腿骨的动脉部署到 20-25 F 鞘的 6 台 F Perclose Proglide 设备。缝术被固定在过程的结束关上动脉切开术。经历了用在 2009 年 12 月和 2010 年 11 月(组 A ) 之间的 Preclosing 技术的大动脉的修理与那些用相比的胸的 endovascular 的病人的医药记录外科大腿骨从 2008 年 1 月缩小到 2009 年 11 月(组 B ) 。结果措施包括了技术成功的率,早复杂并发症,麻醉方法,过程时间,心脏的照顾单位( CCU )停留,分泌物的从过程的时间,医院停留,过程开销,在二个组之间的医院 cost.Results ,在基线特征没有重要差别,在 endograft 模型或侧面。技术成功率是 100.0%(85/85 ) 在组 A 对(147/151 )97.4% 不在组 B (P 0.05 ).There 是在两个组的存取相关的死亡。与组 B 相比,早复杂并发症的发生是在组 A 的少数, 9.4%(8/85 ) 对 22.5%(34/151 )(P 0.01 ) 。有有意识的镇静的本地麻醉在组 A 更经常被使用, 68.2%(58/85 ) 对 51.7%(78/151 ) 在组 B (P0.01 ) 。过程持续时间更短,(96 琠浩 ? 慷 ? ㄨ ? 2 ? 鰘? 鰘吗?? | NI Zhong-han LUO Jian-fang HUANG Wen-hui LIU Yuan XUE Ling FAN Rui-xin CHEN Ji-yan | 2011 | Chinese Medical Journal2011，，6： | 19 |
| 6 | Variations in net primary productivity and its relationships with warming climate in the permafrost zone of the Tibetan Plateau显示文摘温暖的气候触发的永久冻土降级处于土壤条件导致重要变化,并且进一步在植被上贡献明显的影响。然而,更不在网里关于差别被知道主要生产率(NPP ) 和在在不同植被类型和西藏的高原上的永久冻土地区的各种各样的类型之中的 NPP 和温暖的温度之间的关系。因而,遥远地察觉到陆地表面温度(LST ) 和从 MODIS 站台的 NPP 被用来调查植被 NPP 的反应到温暖气候,并且关联为学习区域被扩大规模。我们的结果从西方显示了 NPP 的著名增加到东方,并且显著地在西藏的高原的永久冻土地区从 2000 ~ 2010 与增加的 LST 一起增加了年度 NPP。同时,为各种各样的植被类型并且在有与温暖温度的关系的永久冻土地区的不同类型的增加的 NPP 被揭示。在连续永久冻土地区的 NPP 有最大的敏感到变化 LST,并且森林 NPP 介绍了最明显的反应。在在各种各样的规模的 NPP 和 LST 之间的积极关联显示了在西藏的高原的永久冻土地区在植被碳隐遁上温暖 LST 的提高的效果。鉴于到在这个高原上温暖温度的 NPP 的著名反应,进一步的遥感需要采用了在植被上揭示永久冻土降级和它的相关效果的地位。 | MAO Dehua LUO Ling WANG Zongming ZHANG Chunhua REN Chunying | 2015 | Journal of Geographical Sciences2015，25，8： | 18 |
| 7 | Prevalence, awareness, treatment, and control of hypertension in the non-dialysis chronic kidney disease patients显示文摘 | ZHENG Ying CAI Guang-yan CHEN Xiang-mei FU Ping CHEN Jiang-hua DING Xiao-qiang YU Xue-qing LIN Hong-li LIU Jian XIE Ru-juan WANG Li-ning NI Zhao-hui LIU Fu-you YIN Ai-ping XING Chang-ying WANG Li SHI Wei LIU Jian-she HE Ya-ni DING Guo-hua LI Wen-ge WU Guang-li MIAO Li-ning CHEN Nan SU Zhen MEI Chang-lin ZHAO Jiu-yang GU Yong BAI Yun-kai LUO Hui-min LIN Shan CHEN Meng-hua GONG Li YANG Yi-bin YANG Xiao-ping LI Ying WAN Jian-xin WANG Nian-song LI Hai-ying XI Chun-sheng HAO Li XU Yan FANG Jing-ai LIU Bi-cheng LI Rong-shan WANG Rong ZHANG Jing-hong WANG Jian-qin LOU Tan-qi SHAO Feng-min MEI Feng LIU Zhi-hong YUAN Wei-jie SUN Shi-ren ZHANG Ling ZHOU Chun-hua CHEN Qin-kai JIA Shun-lian GONG Zhi-feng GUAN Guang-ju XIA Tian ZHONG Liang-bao | 2013 | Chinese Medical Journal2013，，12： | 16 |
| 8 | Contrast-enhanced ultrasound:Improving the preoperative staging of hepatocellular carcinoma and guiding individual treatment显示文摘AIM:To investigate the clinical role of contrast-enhanced ultrasound(CEUS) combined with contrast-enhanced computed tomography(CE-CT) or magnetic resonance imaging to improve the preoperative staging of hepatocellular carcinoma(HCC) and guide surgical decisionmaking.METHODS:Sixty-nine patients who underwent liver resection for HCC in our center were enrolled prospectively in the study.CEUS and CE-CT/MRI were performed before surgery.Intraoperative ultrasound(IOUS)wascarried out after liver mobilization.Lesions depicted by each imaging modality were counted and mapped.To investigate the impact of tumor size on the study,we divided the patients into two groups,the'Smaller group'(S-group,≤5 cm in diameter)and the'Largergroup'(L-group,>5 cm in diameter).The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of CE-CT/MRI,CEUS,IOUS,CEUS+CE-CT/MRI and the tumor node metastasis staging of tumors were calculated and compared.Changes in the surgical strategy as a result of CEUS and IOUS were analyzed.RESULTS:One hundred and twenty-seven nodules,comprising 94 HCCs confirmed by histopathology and33 benign lesions confirmed by histopathology and follow-up,were identified in 69 patients.The overall diagnostic sensitivity rates of CE-CT/MRI,CEUS,IOUS and CEUS+CE-CT/MRI were 78.7%,89.4%,89.4%and 89.4%,respectively.There was a significant difference between CEUS+CE-CT/MRI and CE-CT/MRI(P=0.046).Combining CEUS with CT or MRI increased,the diagnostic specificity compared with CT/MRI,CEUS and IOUS,and this difference was statistically significant(100%,72.7%,97.0%,and 69.7%,P=0.004,P=0.002,P=0.002,respectively).The diagnostic accuracy was significantly higher for CEUS+CT/MRI compared with CT/MRI(92.1%vs 77.2%,P=0.001).The TNM staging of tumors based on CEUS+CE-CT/MRI approximated to the final pathological TNM staging(P=0.977).There was a significant difference in the accuracy of TNM staging when comparing CEUS+CECT/MRI with CE-CT/MRI(P=0.002).Before surgery,strategies were changed in 15.9%(11/69)of patients as a result of CEUS.Finally,only 5.7%(4/69)of surgical strategies were changed because of IOUS findings.In the S-group,CEUS revealed 12 false positive lesions,including seven false positive lesions that were diagnosedby preoperative imaging examinations and five by IOUS.In contrast,in the L-group,IUOS revealed eight new malignant lesions;six of these lesions were true HCCs that were also identified by preoperative CEUS.CONCLUSION:CEUS combined with CT or MRI improves the accuracy of preoperative staging for hepatocellular carcinoma and may help to guide individualized treatment for patients with HCC.CEUS may better identify non-malignant lesions in patients with small tumors and discover new malignant lesions in patients with large tumors. | Xiao-Yun Zhang Yan Luo Tian-Fu Wen Li Jiang Chuan Li Xiao-Fei Zhong Jing-Yi Zhang Wen-Wu Ling Lu-Nan Yan Yong Zeng Hong Wu | 2014 | World Journal of Gastroenterology2014，20，35： | 16 |
| 9 | Giant photonic spin Hall effect in momentum space in a structured metamaterial with spatially varying birefringence显示文摘The photonic spin Hall effect(SHE)in the reflection and refraction at an interface is very weak because of the weak spin-orbit interaction.Here,we report the observation of a giant photonic SHE in a dielectric-based metamaterial.The metamaterial is structured to create a coordinate-dependent,geometric Pancharatnam–Berry phase that results in an SHE with a spin-dependent splitting in momentum space.It is unlike the SHE that occurs in real space in the reflection and refraction at an interface,which results from the momentum-dependent gradient of the geometric Rytov–Vladimirskii–Berry phase.We theorize a unified description of the photonic SHE based on the two types of geometric phase gradient,and we experimentally measure the giant spin-dependent shift of the beam centroid produced by the metamaterial at a visible wavelength.Our results suggest that the structured metamaterial offers a potential method of manipulating spin-polarized photons and the orbital angular momentum of light and thus enables applications in spin-controlled nanophotonics. | Xiaohui Ling Xinxing Zhou Xunong Yi Weixing Shu Yachao Liu Shizhen Chen Hailu Luo Shuangchun Wen Dianyuan Fan | 2015 | Light(Science & Applications)2015，4，1： | 15 |
| 10 | Effects of the TREM-1 pathway modulation during empyema in rats显示文摘触发受体的激活面对微生物引起的部件在 myeloid cells-1 (TREM-1 ) 上表示了的背景放大煽动性的反应。学习是在 rats.Methods 成年人男性 Wistar 老鼠在蓄脓症期间调查 TREM-1 小径的调整的效果的礼品的目的受到 Pseudomonas aeruginosa 和葡萄球菌 aureus 的 intrapleural 注射导致的蓄脓症。动物被对待与 LP17 (一个合成 TREM-1 禁止者) ,控制肽,或车辆(正常盐) 。微分房间计数,流动 cytometry 和组织学的检查被执行评估本地煽动性的改变。肿瘤坏死因素的集中--,尽管在肋膜的流出的白血球的每种类型的微分计数没被 LP17 影响,在肋膜的流出和浆液的 interleukin-1 ,和 interleukin-6 被连接酶的 immunosorbent assay.Results 测量,在嗜中性的数字的显著减小在 LP17 被看见由于两个的减小对待老鼠肋膜的流出体积和全部的房间数。LP17 管理在肿瘤坏死因素损害了集中举起 -- ,在肋膜的流出和浆液的 interleukin-l,和 interleukin-6。在 LP17 的幸存率对待老鼠,这被发现在控制 rats.Conclusion 比那高得多由 LP17 的使用的 TREM-1 小径的调整看起来在在在 attenuating 的老鼠的蓄脓症期间有益肋膜、全身的煽动性的回答。 | LUO Ling ZHOU Qiong CHEN Xiao-ju QIN Shou-ming MA Wan-li SHI Huan-zhong | 2010 | Chinese Medical Journal2010，，12： | 15 |
| 11 | A cyclic nucleotide-gated channel mediates cytoplasmic calcium elevation and disease resistance in rice显示文摘The transient elevation of cytoplasmic calcium is essential for pathogen-associated molecular pattern(PAMP)-triggered immunity(PTI).However,the calcium channels responsible for this process have remained unknown.Here,we show that rice CDSI(CELL DEATH and SUSCEPTIBLE to BLAST 1)encoding OsCNGC9;a cyclic nucleotide-gated channel protein,positively regulates the resistance to rice blast disease.We show that OsCNGC9 mediates PAMP-induced Ca2+influx and that this event is critical for PAMPs-triggered ROS burst and induction of PTI-related defense gene expression.We further show that a PTI related receptor-lih cytoplasmic kinase OsRLCK185 physically interacts with and phosphorylates OsCNGC9 to activate its channel activity.Our results suggest a signaling cascade linking pattern recognition to calcium channel activation,which is required for initiation of PTI and disease resistance in rice. | Jiachang Wang Xi Liu An Zhang Yulong Ren Fuqing Wu Gang Wang Yang Xu Cailin Lei Shanshan Zhu Tian Pan Yongfei Wang Huan Zhang Fan Wang Yan-Qiu Tan Yupeng Wang Xin Jin Sheng Luo Chunlei Zhou Xiao Zhang Jinling Liu Shuai Wang Lingzhi Meng Yihua Wang Xi Chen Qibing Lin Xin Zhang Xiuping Guo Zhijun Cheng Jiulin Wang Yunlu Tian Shijia Liu Ling Jiang Chuanyin Wu Ertao Wang Jian-Min Zhou Yong-Fei Wang Haiyang Wang Jianmin Wan | 2019 | Cell Research2019，29，10： | 13 |
| 12 | Parthenogenetic haploid embryonic stem cells produce fertile mice显示文摘 | Haifeng Wan Zhengquan He Mingzhu Dong Tiantian Gu Guan-Zheng Luo Fei Teng Baolong Xia Wei Li Chunjing Feng Xin Li Tianda Li Ling Shua Rui Fu Liu Wang Xiu-Jie Wang Xiao-Yang Zhao Qi Zhou | 2013 | Cell Research2013，23，11： | 13 |
| 13 | Electro-acupuncture at Conception and Governor vessels and transplantation of umbilical cord bloodderived mesenchymal stem cells for treating cerebral ischemia/reperfusion injury显示文摘Mesenchymal stem cell transplantation is a novel means of treating cerebral ischemia/reperfusion,and can promote angiogenesis and neurological functional recovery.Acupuncture at Conception and Governor vessels also has positive effects as a treatment for cerebral ischemia/reperfusion.Therefore,we hypothesized that electro-acupuncture at Conception and Governor vessels plus mesenchymal stem cell transplantation may have better therapeutic effects on the promotion of angiogenesis and recovery of neurological function than either treatment alone.In the present study,human umbilical cord blood-derived mesenchymal stem cells were isolated,cultured,identified and intracranially transplanted into the striatum and subcortex of rats at24 hours following cerebral ischemia/reperfusion.Subsequently,rats were electro-acupunctured at Conception and Governor vessels at 24 hours after transplantation.Modified neurological severity scores and immunohistochemistry findings revealed that the combined interventions of electro-acupuncture and mesenchymal stem cell transplantation clearly improved neurological impairment and up-regulated vascular endothelial growth factor expression around the ischemic focus.The combined intervention provided a better outcome than mesenchymal stem cell transplantation alone.These findings demonstrate that electro-acupuncture at Conception and Governor vessels and mesenchymal stem cell transplantation have synergetic effects on promoting neurological function recovery and angiogenesis in rats after cerebral ischemia/reperfusion. | Haibo Yu Pengdian Chen Zhuoxin Yang Wenshu Luo Min Pi Yonggang Wu Ling Wang | 2014 | Neural Regeneration Research2014，9，1： | 13 |
| 14 | Reservoir characteristics,formation mechanisms and petroleum exploration potential of volcanic rocks in China显示文摘Characterized by complex lithology and strong heterogeneity, volcanic reservoirs in China developed three reservoir space types: primary pores, secondary pores and fractures. The formation of reservoir space went through the cooling and solidification stage(including blast fragmentation, crystallization differentiation and solidification)and the epidiagenesis stage(including metasomatism, filling, weathering and leaching, formation fluid dissolution and tectonism). Primary pores were formed at the solidification stage, which laid the foundation for the development and transformation of effective reservoirs. Secondary pores were formed at the epidiagenesis stage, with key factors as weathering and leaching, formation fluid dissolution and tectonism. In China, Mesozoic–Cenozoicvolcanic rocks developed in the Songliao Basin and Bohai Bay Basin in the east and Late Paleozoic volcanic rocks developed in the Junggar Basin, Santanghu Basin and Tarim Basin in the west. There are primary volcanic reservoirs and secondary volcanic reservoirs in these volcanic rocks, which have good accumulation conditions and great exploration potential. | Zhi-Guo Mao Ru-Kai Zhu Jing-Lan Luo Jing-Hong Wang Zhan-Hai Du Ling Su Shao-Min Zhang | 2015 | Petroleum Science2015，12，1： | 12 |
| 15 | COVID-19-like symptoms observed in Chinese tree shrews infected with SARS-CoV-2显示文摘Thecoronavirusdisease2019(COVID-19)pandemic continues to pose a global threat to the human population. Identifying animal species susceptible to infection with the SARS-CoV-2/HCoV-19 pathogen is essential for controlling the outbreak and for testing valid prophylactics or therapeutics based on animal model studies. Here,different aged Chinese tree shrews(adult group, 1 year old;old group, 5–6 years old), which are close relatives to primates, were infected with SARS-CoV-2. X-ray, viral shedding, laboratory, and histological analyses were performed on different days postinoculation(dpi). Results showed that Chinese tree shrews could be infected by SARS-CoV-2. Lung infiltrates were visible in X-ray radiographs in most infected animals. Viral RNA was consistently detected in lung tissues from infected animals at 3,5, and 7 dpi, along with alterations in related parameters from routine blood tests and serum biochemistry, including increased levels of aspartate aminotransferase(AST) and blood urea nitrogen(BUN). Histological analysis of lung tissues from animals at 3 dpi(adult group) and 7 dpi(old group) showed thickened alveolar septa and interstitial hemorrhage. Several differences were found between the two different aged groups in regard to viral shedding peak. Our results indicate that Chinese tree shrews have the potential to be used as animal models for SARS-CoV-2 infection. | Ling Xu Dan-Dan Yu Yu-Hua Ma Yu-Lin Yao Rong-Hua Luo Xiao-Li Feng Hou-Rong Cai Jian-Bao Han Xue-Hui Wang Ming-Hua Li Chang-Wen Ke Yong-Tang Zheng Yong-Gang Yao | 2020 | Zoological Research2020，41，5： | 12 |
| 16 | The emergence, development and regional differences of mixed farming of rice and millet in the upper and middle Huai River Valley, China显示文摘Mixed farming of rice and millet is one of the basic agricultural modes in the upper and middle Huai River Valley(HRV). According to the latest data, this agricultural mode appeared during the middle and late Peiligang Culture(7.8–7.0 ka BP) in the upper HRV, and then became a common subsistence economy in the end of the Neolithic(5.0–4.0 ka BP) in both the upper and middle HRV. However, it is still not clear how this mixed farming developed in the upper HRV after its occurrence, nor are the regional differences in the development of mixed farming between the upper and middle HRV during the Neolithic completely understood. In this paper, flotation and starch analyses were conducted on samples from eight archaeological sites in the upper and middle HRV. The results indicate that the mixed farming of rice and millet first appeared in the later phase of the middle Neolithic in the regions of the Peiligang Culture, then developed quite rapidly in the late Neolithic(6.8–5.0 ka BP), finally becoming the main subsistence economy at the end of the Neolithic in the upper HRV. However, there are obvious differences in the emergence and development of agriculture between the middle and upper HRV. Rice farming was the only agricultural system during the middle Neolithic, lasting until the end of the Neolithic, when mixed farming appeared in the middle HRV. Furthermore, although mixed farming appeared in both the upper and middle HRV during the end of the Neolithic, the roles of rice, foxtail millet and broomcorn millet in the subsistence economy were not the same. In general, millet was more widely cultivated than rice in the upper HRV, but rice occupied the same or a slightly more prominent position in the middle HRV at the end of the Neolithic. These results are significant for understanding the process of agricultural development and transformation, as well as human adaptation to climatic and cultural variability duringthe Neolithic. | YANG YuZhang CHENG ZhiJie LI WeiYa YAO Ling LI ZhanYang LUO WuHong YUAN ZengJian ZHANG Juan ZHANG JuZhong | 2016 | Science China Earth Sciences2016，59，9： | 11 |
| 17 | Clinical Value of Whole-body Magnetic Resonance Diffusion Weighted Imaging on Detection of Malignant Metastases显示文摘Objective To evaluate the value of whole-body diffusion weighted imaging(WB-DWI) on detection of malignant metastasis.Methods Forty-six patients with malignant tumors underwent WB-DWI examinations between April 2007 and August 2007 in our hospital.Before WB-DWI examination,the primary cancers of all the patients were confirmed by pathology,and the TNM-stage was assessed with conventional magnetic resonance imaging(MRI) or computed tomography(CT).WB-DWI was performed using short TI inversion recovery echo-planar imaging(STIR-EPI) sequence.Abnormal high signal intensities on WB-DWI were considered as metastases.The results of WB-DWI were compared with other imaging modalities.For the assessment of the diagnostic capability of WB-DWI,WB-DWI were compared with CT for demonstrating mediastinal lymph node metastases and lung metastases,and with conventional MRI for demonstrating metastases in other locations.Results WB-DWI demonstrated 143 focuses,14 of which were diagnosed to be benign lesions in routine imaging.The number of bone metastases depicted on WB-DWI and routine imaging was 85 and 86;lymph node metastases was 17 and 18;liver metastases was 14 and 14;lung metastases was 4 and 8;and brain metastases was 6 and 8,respectively.WB-DWI failed to detect 12 metastatic lesions including 3 osteoplastic bone metastases,4 lung metastases,3 mediastinal lymph node metastases,and 2 brain metastases.Four metastatic lesions including 2 deltopectoral lymph nodes and 2 rib metastases were detected with WB-DWI alone,all of which evolved greatly during clinical follow-up for more than 6 months.WB-DWI had higher detection rates for metastatic lesions in liver,bone,and lymph nodes than those in lung and brain(χ2=30,P<0.001).Conclusions WB-DWI could detect most of metastatic lesions that were diagnosed with conventional MRI and CT.The limitations of WB-DWI might be had high false-positive rate and low efficiency in detecting mediastinal lymph node,brain,and lung metastases. | Cheng Li Zhen-sheng Liu Xian-mao Du Ling He Jian Chen Wei Wang Fei Sun Fang Du Zhi-gang Luo Zhen-long Xue Yi Zhao Chang-wu Zhou | 2009 | Chinese Medical Sciences Journal2009，24，2： | 11 |
| 18 | Amelioration of influenza virus-induced reactive oxygen species formation by epigallocatechin gallate derived from green tea显示文摘瞄准: 学习是否 epigallocatechin gallate (EGCG ) ,绿导出茶的多酚,在 vitro 并且在 vivo 的施加的反流行性感冒 A 病毒活动。 | Jia-xin LING Fei WEI Ning LI Jin-lin LI Liang-jun CHEN Yuan-yuan LIU Fan LUO Hai-rong XIONG Wei HOU Zhan-qiu YANG | 2012 | Acta Pharmacologica Sinica2012，33，12： | 11 |
| 19 | Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells显示文摘 | Peng-fei GE Ji-zhou ZHANG Xiao-fei WANG Fan-kai MENG Wen-chen LI Yong-xin LUAN Feng LING Yi-nan LUO | 2009 | Acta Pharmacologica Sinica2009，30，7： | 11 |
| 20 | A novel polyaniline/mesoporous carbon nano-composite electrode for asymmetric supercapacitor显示文摘polyaniline/mesoporous 碳(PANI/CMK-3 )nano 合成的一篇小说与用作支持的 mesoporous 碳(CMK-3 ) 被准备。电气化学的不对称的电容器被分别地把合成的 PANI/CMK-3 和 CMK-3 用作积极、否定的电极成功地设计了。结果证明不对称的电容器的分泌物电容能在 5 mA/cm2 的当前的密度和 1.4 V 的房间电压下面到达 87.4 F/g。不对称的电容器的精力密度直到有 206 W/kg 的力量密度的 23.8 Wh/kg。而且,用这 PANI/CMK-3 的 PANI/CMK-3CMK-3 不对称的电容器 nano 合成能快速被激活并且拥有高 chargedischarge 效率。 | Jian Jun Cai Ling Bin Kong Jing Zhang Yong Chun Luo Long Kang | 2010 | Chinese Chemical Letters2010，21，12： | 11 |
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