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| 1 | 在有分散的胃的息肉的病人的 colorectal 息肉的风险: 盒子控制研究显示文摘 AIM:To assess the risk of colonic polyps,adenomas and advanced neoplastic lesions(ANL) in patients with sporadic gastric polyps,especially those with fundic gland polyps(FGP).METHODS:Clinical records of patients who had performed an upper and a lower digestive endoscopy between September 2007 and August 2008 were retrospectively analyzed.A case-control study was carried out,calling patients with gastric polyps as 'cases' and patients without gastric polyps as 'controls'.The risk of colonic polyps,adenomas and ANL(villous component ≥ 25%,size ≥ 10 mm,or high grade dysplasia) was assessed [odds ratio(OR) and its corresponding 95%CI].RESULTS:Two hundred and forty seven patients were analyzed:78 with gastric polyps(cases) and 169 without gastric polyps(controls).Among the cases,the majority of gastric polyps were FGP(80%,CI:69-88) and hyperplastic(20%,CI:12-31);25% had colonic polyps(25% hyperplastic and 68% adenomas,from which 45% were ANL).Among the controls,20% had colonic polyps(31% hyperplastic and 63% adenomas,from which 41% were ANL).The patients with sporadic FGP had an OR of 1.56(CI:0.80-3.04) for colonic polyps,an OR of 1.78(CI:0.82-3.84) for colonic adenomas,and an OR of 0.80(CI:0.21-2.98) for ANL.Similar results were found in patients with gastric polyps in general.CONCLUSION:The results of this study did not show more risk of colorectal adenomas or ANL neither in patients with sporadic gastric polyps nor in those with FGP. | Daniel Gustavo Cimmino José Manuel Mella Pablo Luna Raquel González Lisandro Pereyra Carolina Fischer Adriana Mohaidle Beatriz Vizcaino Mario Andres Medrano Adrián Hadad Silvia Pedreira Luis Boerr | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，5： | 12 |
| 2 | Identification and Characterization of Sulfur Compounds in Straight-Run Diesel Using Comprehensive Two-Dimensional GC Coupled with TOF MS显示文摘The solid-phase extraction using Pd-Al2O3 as the stationary phase was employed to pre-separate the sulfur compounds in straight-run diesel. The isolating effect was evaluated quantitatively by gas chromatography with a sulfur chemiluminescence detector to harvest a satisfactory result. The identification of the structure of sulfur compounds by comprehensive two-dimensional gas chromatography coupled with the time-of-flight mass spectrometry indicated that cyclo-sulfides, benzothiophenes, dibenzothiophenes, dihydro-benzothiophenes and tetrahydro-dibenzothiophenes were included in straightrun diesel obtained from the Arab medium crude(AM). A total of 259 individual compounds were detected and their molecular structures were identified. The analytical method was approved as an effective way to characterize the composition of sulfur compounds, which reduced the interference of other compounds, facilitated the data presentation and provided more detailed information about molecular composition of sulfur compounds. | Niu Luna Liu Zelong Tian Songbai | 2014 | China Petroleum Processing & Petrochemical Technology2014，16，3： | 10 |
| 3 | PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis显示文摘AIM: To identify gene mutations in PRSS1 and SPINK1 in individuals with early onset idiopathic chronic or recurrent acute pancreatitis.METHODS: The cationic trypsinogen gene(PRSS1; exons 2 and 3) and the serine protease inhibitor Kazal 1 gene(SPINK1; exon 3) were selectively amplified and sequenced from blood samples of 19 patients admitted to the Pancreas Clinic at our institution with chronic pancreatitis and/or idiopathic recurrent acute pancreatitis that were diagnosed or with onset before age 35. Fifty healthy volunteers served as controls. Whole blood samples were collected and gene specific sequences were amplified by polymerase chain reaction(PCR). All PCR products were subsequently sequenced in order to identify the presence of any mutations.RESULTS: Nineteen patients with pancreatitis(14 males; median age 24 years, range 15-48 years) were included in this study, of which five showed the presence of gene mutations. Direct sequencing results indicated the presence of two previously unidentified mutations in exon 2 of PRSS1(V39E and N42S) in two patients with recurrent acute pancreatitis. Two cases had the N34 S SPINK1 mutation. Analysis of the relatives of one patient homozygous for this mutation showed that five of the six family members carried the N34 S SPINK1 mutation. Of these members, three were healthy heterozygous carriers and two were homozygotes(one sibling had diabetes, the other was healthy). Another patient was heterozygous for a novel SPINK1 mutation located on exon 3(V46D). All members from this patient's family had normal genotypes, indicating that it was a de novo mutation. No mutations in either gene were present in the control subjects. CONCLUSION: Two novel PRSS1 mutations and one novel SPINK1 mutation were identified in Mexican patients with early onset idiopathic recurrent acute pancreatitis. | Mario Pelaez-Luna Guillermo Robles-Diaz Samuel Canizales-Quinteros Maria T Tusié-Luna | 2014 | World Journal of Gastroenterology2014，20，33： | 7 |
| 4 | Response of testicular antioxidant enzymes to hexachlorocy clohexane is species specific显示文摘Aim:To find out whether the response of testicular oxidative stess parameters to hexachlorocyclohexane(HCH)is species specific.Methods:In rats and mice(n=5in each group).HCHwas administered at a dose of 20mg/kg/day intraperitoneally for 30daysin0.1ml of refined rgoundnut oil.The control groups received equal volume of the vehicle.Animals were sacrificed 24hours after the last injection and various oxidative stress parameters were measured immediately.Results:The level of both endogenous as well as FeSO4and ascorbic acid-stimulated lipid peroxidation was increased significantly in the HCH-treated rats,whereas the pattern was just the reverse in case of mice.Although the level of H2O2content increased inresponse to HCHinboth groups,a totally different trend was observed for the activity of the principal H2O2-metabolising emzyme,catalase,In case of rats,a significant decline inthe activity of catalase was recorded in response to HCH whereas a sharp augmentation in the enzyme activity was noticed im mice,Similarly,the decreased activity of superoxide dismutase observed in rast remained unaltered in mice.Conclusion:HCH induces oxidative stress in the testis of both rats and mice,However,the pattern of response of testicular oxidative stress parameters seems to be species specific. | Luna Samanta G.B.N. Chainy | 2002 | Asian Journal of Andrology2002，4，3： | 6 |
| 5 | Proteomic signatures of infertile men with clinical varicocele and their validation studies reveal mitochondrial dysfunction leading to infertility显示文摘由他们表示的水平的比较 proteomics 和确认与精索静脉曲张在不肥沃的人在精子蛋白质的分发学习主要差别。为每精索静脉曲张结果的学习特定的估计被联合识别不管他们的临床的精索静脉曲张的舞台和对一个侧面的偏重,在人涉及联系精索静脉曲张的不孕的蛋白质。5 关键蛋白质(PKAR1A, AK7, CCT6B, HSPA2,和 ODF2 ) 的表达式层次在压力反应包含了,包括分子的女伴的精子功能被西方的弄污验证。99 蛋白质是在精索静脉曲张组表示的差别。涉及主要精力新陈代谢和关键精子功能的超过 87% DEP 是在精索静脉曲张组的 underexpressed。在精索静脉曲张组影响的关键蛋白质功能是精子发生,精子活动性,和 mitochondrial 机能障碍,它被西方的弄污进一步验证,支持 proteomics 分析。精索静脉曲张是实质上由于损害的血供应的精力剥夺,组织缺氧,和过高热的一个状态,它被类脂化合物新陈代谢, mitochondrial 电子运输链,和克雷布斯周期的下面规定支持酶。支持 proteomic 分析,兴趣的 5 识别蛋白质的表示被西方的弄污验证。这研究向建立 biomarker “ 作出贡献; fingerprint”根据分子的参数估计精子质量。 | Ashok Agarwal Rakesh Sharma Luna Samanta Damayanthi Durairajanayagam Edmund Sabanegh | 2016 | Asian Journal of Andrology2016，18，2： | 6 |
| 6 | Diagnosis of interatrial block显示文摘 | Antoni Bay, s de Luna Adrian Baranchuk Luis Alberto Escobar Robledo Albert Masso van Roessel Manuel Martinez-Selles | 2017 | Journal of Geriatric Cardiology2017，14，3： | 6 |
| 7 | Ammonium Ion Adsorption and Settleability Improvement Achieved in a Synthetic Zeolite-Amended Activated Sludge显示文摘Municipal wastewater treatment plants typically exhibit two classic problems: high ammonium concentration in water after conventional biological treatment and,in some cases,poor activated sludge sediment ability.Potential solutions to these problems were investigated by adding a synthetic zeolite obtained from coal fly ash to different steps of activated sludge treatment.The experimental results for ammonium removal fit well with the theoretical adsorption isotherms of the Freundlich model with a maximum adsorption capacity of 13.72 mg·g 1.Utilization of this kind of zeolite to improve activated sludge sediment ability is studied for the first time in this work.It is found that the addition of the zeolite(1 g·L 1) to an activated sludge with settling problems significantly enhances its sediment ability and compact ability.This is confirmed by the sludge volume index(SVI),which was reduced from 163 ml·g 1to 70 ml·g 1,the V60value,which was reduced from 894 ml·L 1to 427 ml·L 1,and the zeta potential(ζ),which was reduced from 19.81 mV to 14.29 mV.The results indicate that the addition of this synthetic zeolite to activated sludge,as an additional waste management practice,has a positive impact on both ammonium removal and sludge settleability. | Emilia Otal Luls F. Vilches Yolanda Luna Rodrigo Poblete Juan M. Garcia-Maya Constantino Ferneindez-Pereira | 2013 | Chinese Journal of Chemical Engineering2013，21，9： | 5 |
| 8 | Assessing the host genetic background effects on type 2 diabetes and obesity development in response to mixed–oral bacteria and high-fat diet using the collaborative cross mouse model显示文摘Background: Host genetic background and sex, play central roles in defining the pathogenesis of type 2 diabetes(T2 D), obesity and infectious diseases. Our previous studies demonstrated the utilization of genetically highly diverse inbred mouse lines, namely collaborative cross(CC), for dissecting host susceptibility for the development of T2 D and obesity, showing significant variations following high-fat(42% fat) diet(HFD). Here, we aimed to assessing the host genetic background and sex effects on T2 D and obesity development in response to oral-mixed bacterial infection and HFD using the CC lines.Materials and Methods: Study cohort consists of 97 mice from 2 CC lines(both sexes), maintained on either HFD or Standard diet(CHD) for 12 weeks. At week 5 a group of mice from each diet were infected with Porphyromonas gingivalis(Pg) and Fusobacterium nucleatum(Fn) bacteria(control groups without infection). Body weight(BW) and glucose tolerance ability were assessed at the end time point of the experiment.Results: The CC lines varied(P <.05) at their BW gain and glucose tolerance ability(with sex effect) in response to diets and/or infection, showing opposite responses despite sharing the same environmental conditions. The combination of diet and infection enhances BW accumulation for IL1912, while restraints it for IL72. As for glucose tolerance ability, only females(both lines) were deteriorated in response to infection.Conclusions: This study emphasizes the power of the CC mouse population for the characterization of host genetic makeup for defining the susceptibility of the individual to development of obesity and/or impaired glucose tolerance. | Luna Karkar Hanifa JAbu-Toamih Atamni Asal Milhem Yael Houri-Haddad Fuad A.Iraqi | 2020 | Animal Models and Experimental Medicine2020，3，2： | 5 |
| 9 | Coexistence of papillary thyroid microcarcinoma and mucosa-associated lymphoid tissue lymphoma in a context of Hashimoto's thyroiditis显示文摘Papillary thyroid cancer(PTC)represents 80%-85%of thyroid cancer and its prevalence has been rising in the last decades.Primary thyroid lymphoma(PTL)accounts for 3%of extranodal lymphomas and about 5%of thyroid malignancies,having a prevalence of one or two cases per million people.Mucosa-Associated Lymphoid Tissue lymphoma represents approximately30%of PTL.Both entities have an indolent course and a very good prognosis.Diagnosis is made by ultrasound and fine needle aspiration(FNA)or surgery specimen pathology.They have also been associated with Hashimoto’s thyroiditis(HT),but pathogenesis and its links remains to be known.Treatment remains controversial and surgery is generally accepted in cases of disease limited to thyroid,as the present.Patients with thyroid nodules should be observed and followed.If there is an enlargement by ultrasound or clinical symptoms,FNA should be performed promptly.Patients with HT deserve additional surveillance,since this condition is associated with both PTC and PTL.In this case,the management with surgery and radioactive iodine ablation therapy was effective for both entities.Patients with thyroid nodules should be properly evaluated with ultrasound and thyroid function tests.If there is an enlargement of the neck,reported by symptoms or ultrasound,it requires further investigation.HT is associated to both PTC and PTL so if the enlargement of the nodules is on this context additional tests such as FNA should be performed.In this case,the patient was managed with surgery and radioactive iodine ablation therapy and it was effective for both entities. | Saul Levy-Blitchtein Stefany Plasencia-Rebata Domingo Morales Luna Juana del Valle Mendoza | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，8： | 5 |
| 10 | Management of oligometastatic non-small cell lung cancer patients:Current controversies and future directions显示文摘Oligometastatic non-small cell lung cancer(NSCLC)describes an intermediate stage of NSCLC between localized and widely-disseminated disease.This stage of NSCLC is characterized by a limited number of metastases and a more indolent tumor biology.Currently,the management of oligometastatic NSCLC involves radical treatment(radiotherapy or surgery)that targets the metastatic lesions and the primary tumor to achieve disease control.This approach offers the potential to achieve prolonged survival in patients who,in the past,would have only received palliative measures.The optimal therapeutic strategies for the different scenarios of oligometastatic disease(intracranial vs extracranial disease,synchronous vs metachronous)remain undefined.Given the lack of head-to-head studies comparing radiotherapy to surgery in these patients,the decision to apply surgery or radiotherapy(with or without systemic treatment)must be based on prognostic factors that allow us to classify patients.This classification will allow us to select the most appropriate therapeutic strategy on an individualized basis.In the future,the molecular or microRNA profiles will likely improve the treatment selection process.The objective of the present article is to review the most relevant scientific evidence on the management of patients with oligometastatic NSCLC,focusing on the role of radiotherapy and surgery.We also discuss areas of controversy and future directions. | Felipe Counago Javier Luna Luis Leonardo Guerrero Blanca Vaquero María Cecilia Guillén-Sacoto Teresa González-Merino Begona Taboada Verónica Díaz Belén Rubio-Viqueira Ana Aurora Díaz-Gavela Francisco JoséMarcos Elia del Cerro | 2019 | World Journal of Clinical Oncology2019，10，10： | 5 |
| 11 | Noise-like pulse generation from a thulium-doped fiber laser using nonlinear polarization rotation with different net anomalous dispersion显示文摘A mode-locked thulium-doped fiber laser(TDFL) based on nonlinear polarization rotation(NPR) with different net anomalous dispersion is demonstrated. When the cavity dispersion is-1.425 ps^2, the noise-like(NL) pulse with coherence spike width of 406 fs and pulse energy of 12.342 nJ is generated at a center wavelength of 2003.2 nm with 3 dB spectral bandwidth of 23.20 nm. In the experimental period of 400 min, the 3 dB spectral bandwidth variation, the output power fluctuation, and the central wavelength shift are less than 0.06 nm, 0.04 d B, and0.4 nm, respectively, indicating that the NPR-based TDFL operating in the NL regime holds good long-term stability. | Shuo Liu Fengping Yan Yang Li Luna Zhang Zhuoya Bai Hong Zhou Yafei Hou | 2016 | Photonics Research2016，4，6： | 5 |
| 12 | The IBI1 Receptor ofβ-Aminobutyric Acid Interacts with VOZ Transcription Factors to Regulate Abscisic Acid Signaling and Callose-Associated Defense显示文摘Extemal and internal signals can prime the plant immune system for a faster and/or stronger response to pathogen attack.β-aminobutyric acid(BABA)is an endogenous stress metabolite that induces broad-spectrum disease resistance in plants.BABA perception in Arabidopsis is mediated by the aspartyl tRNA synthetase IBI1,which activates priming of multiple immune responses,including callose-associated cell wall defenses that are under control by abscisic acid(ABA).However,the immediate signaling components after BABA perception by IBI1,as well as the regulatory role of ABA therein,remain unknown.Here,we have studied the early signaling events controlling IBI1-dependent BABA-induced resistance(BABAIR),using untargeted transcriptome and protein interaction analyses.Transcriptome analysis revealed that IBI1-dependent expression of BABA-IR against the biotrophic oomycete Hyaloperonospora arabidopsidis is associated with suppression of ABA-inducible abiotic stress genes.Protein interaction studies identified the VOZ1 and VOZ2 transcription factors(TFs)as IBI1-interacting partners,which are transcrip-tionally induced by ABA but suppress pathogen-induced expression of ABA-dependent genes.Furthermore,we show that VOZ TFs require nuclear localization for their contribution to BABA-IR by mediating augmented expression of callose-associated defense.Collectively,our study indicates that the IBI1-VOZ signaling module channels pathogen-induced ABA signaling toward cell wall defense while simultaneously suppressing abiotic stress-responsive genes. | Roland E.Schwarzenbacher Grace Wardell Joost Stassen Emily Guest Peijun Zhang Estrella Luna Jurriaan Ton | 2020 | Molecular Plant2020，13，10： | 4 |
| 13 | 前期动载对低塑性粉土静态和动态强度的影响显示文摘低塑性粉土广泛存在于世界范围内,在地震中容易产生液化现象,然而一些基础设施破坏不仅见于地震中也发生在地震后,这就决定了研究低塑性粉土震后行为的必要性。以美国中部密西西比河沿岸低塑性粉土为试验材料,研究动载对低塑性粉土静态和动态强度的影响。在动三轴仪上对试样施加动载引起超孔隙水压力,排水重固结后,分别对2组震动后试样进行静态和动态三轴强度试验。试验结果表明,当液化水平小于0.70时,前期动载对粉土的不排水剪切强度影响不大;相反地,只有当液化水平大于0.70,密西西比河沿岸粉土的震后重固结体积应变和不排水剪切强度才伴随着液化水平的提高显著增加,但相对于砂土而言,重固结体积应变在较低的液化水平时即有明显增加。与前期动载对不排水剪切强度的影响不同,当动载所引起的液化水平为0.35或轴向应变为0.2%时,抗液化强度达到最大值,若液化水平大于0.35,抗液化强度伴随液化水平提高而降低。如果前期荷载引起较大的压应变,在重固结后第二次动载循环中,轴向压力相比轴向拉力引起较小的超孔隙水压力。 | 王树英 阳军生 LUNA R | 2013 | 岩石力学与工程学报2013，32，2： | 4 |
| 14 | Studying host genetic background effects on multimorbidity of intestinal cancer development,type 2 diabetes and obesity in response to oral bacterial infection and high-fat diet using the collaborative cross(CC)lines显示文摘Background:Multimorbidity of intestinal cancer(IC),type 2 diabetes(T2D)and obesity is a complex set of diseases,affected by environmental and genetic risk factors.High-fat diet(HFD)and oral bacterial infection play important roles in the etiology of these diseases through inflammation and various biological mechanisms.Methods:To study the complexity of this multimorbidity,we used the collaborative cross(CC)mouse genetics reference population.We aimed to study the multimorbidity of IC,T2D,and obesity using CC lines,measuring their responses to HFD and oral bacterial infection.The study used 63 mice of both sexes generated from two CC lines(IL557 and IL711).For 12 weeks,experimental mice were maintained on specific dietary regimes combined with co-infection with oral bacteria Porphyromonas gingivalis and Fusobacterium nucleatum,while control groups were not infected.Body weight(BW)and results of a intraperitoneal glucose tolerance test(IPGTT)were recorded at the end of 12 weeks,after which length and size of the intestines were assessed for polyp counts.Results:Polyp counts ranged between 2 and 10 per CC line.The combination of HFD and infection significantly reduced(P<.01)the colon polyp size of IL557 females to 2.5 cm 2,compared to the other groups.Comparing BW gain,IL557 males on HFD gained 18 g,while the females gained 10 g under the same conditions and showed the highest area under curve(AUC)values of 40000-45000(min mg/dL)in the IPGTT.Conclusion:The results show that mice from different genetic backgrounds respond differently to a high fat diet and oral infection in terms of polyp development and glucose tolerance,and this effect is gender related. | Asal Milhem Hanifa J.Abu Toamih-Atamni Luna Karkar Yael Houri-Haddad Fuad A.Iraqi | 2021 | Animal Models and Experimental Medicine2021，4，1： | 4 |
| 15 | Role of advanced magnetic resonance imaging in the assessment of malignancies of the mediastinum显示文摘In the new era of functional magnetic resonance imaging(MRI), the utility of chest MRI is increasing exponentially due to several advances, including absence of ionizing radiation, excellent tissue contrast and high capability for lesion characterization and treatment monitoring. The application of several of these diagnostic weapons in a multiparametric fashion enables to better characterize thymic epithelial tumors and other mediastinal tumoral lesions, accurate assessment of the invasion of adjacent structures and detection of pathologic lymph nodes and metastasis. Also, 'do not touch lesions' could be identified with the associated impact in the management of those patients. One of the hotspots of the multiparametric chest MR is its ability to detect with acuity early response to treatment in patients with mediastinal malignant neoplasms. This has been related with higher rates of overall survival and progression free survival.Therefore, in this review we will analyze the current functional imaging techniques available(18 F-Fluorodeoxiglucose positron emission tomography/computed tomography, diffusion-weighted imaging, dynamic contrast-enhanced MRI, diffusion tensor imaging and MR spectroscopy) for the evaluation of mediastinal lesions, with a focus in their correct acquisition and post-processing. Also, to review the clinical applications of these techniques in the diagnostic approach of benign and malignant conditions of the mediastinum. | Jordi Broncano Ana María Alvarado-Benavides Sanjeev Bhalla Antonio álvarez-Kindelan Constantine A Raptis Antonio Luna | 2019 | World Journal of Radiology2019，11，3： | 4 |
| 16 | Prediction of sudden death in elderly patients with heart failure显示文摘最,心失败(HF ) 联系了死亡由于突然的心脏的死亡(SCD ) 和变得更坏的 HF,特别地在减少的喷射的情况中部分。预言并且阻止 SCD 是一个重要目标,但是最工作不包括或有先进年龄的很少病人,和在有 HF 的老病人的 SCD 的预防仍然是争论的。处于 SCD 的年度率的最近的减小最近被描述了,但是如果这在先进年龄病人也是真的,它不是清楚的。尽管医生们经常有有 HF 的老病人主要死于泵失败的感觉,年龄与 SCD 被联系,低估 SCD 的重要性。被联系了到 SCD 的另外的临床的变量是症状,纽约心协会功能的类, ischemic 原因,和 comorbidities (长期的妨碍的肺的疾病,肾的机能障碍和糖尿病) 。应该也被考虑的一些测试结果被让喷射室部分和直径, natriuretic 肽,非支撑的室的心悸亢进和自治畸形。所有这些标记的联合可能是最好的选择预言 SCD。不同风险分数被描述了并且尽管为老人口没有特定的,当一个风险预言者和一些与吝啬的年龄在人口被开发,最包括年龄 > 65 年。最后,强调这些分数应该能预言 SCD 的任何类型作为是重要的尽管大多数由于 tachyarrhythmias, bradyarrhythmias 也起一个作用,特别地在情况中老。 | Ana Ayesta Helena Martinez-Sellest Antonio Bayes de Luna Manuel Martinez-Selles | 2018 | Journal of Geriatric Cardiology2018，15，2： | 4 |
| 17 | Pilose antler polypeptides ameliorates hypoxic- ischemic encephalopathy by activated neurotrophic factors and SDF1/CXCR4 axis in rats显示文摘Hypoxic-ischemic encephalopathy (催促) 是与高死亡和病态被联系的一个复杂条件。然而,很少有希望的处理为催促存在。在现在的学习,中央目的是识别覆有毛的鹿角多肽(奶头) 的治疗学的效果在上在老鼠催促。Sprague-Dawley (SD ) 老鼠(14 天旧) 被使用并且把组划分了成三包括控制组, hypoxic 局部缺血(嗨) 组和奶头组。在 21 天处理以后,运动活动在对待奶头的老鼠被改进,大脑萎缩被减少,服的浮肿被减轻到某程度。实时量的聚合酶链反应(RT-qPCR ) 分析显示奶头管理减少了在马头鱼尾的怪兽的煽动性的 cytokines 和 apoptosis 基因的表情与相比嗨组。而且,与神经营养的因素有关的基因的 mRNA 表情显著地在马头鱼尾的怪兽被增加。另外,氧化压力标记的表情都在奶头管理以后是下面调整的。而且,奶头起来调整 mRNA 和 SDF1 和 CXCR4 的蛋白质层次,它可以激活 SDF1/CXCR4 轴到节制大脑损害。这些结果建议那个奶头可以潜在地在处理被使用催促。 | Tao Wu Luna Yang Yan Chen Yinhua Ni Jianguo Jiang Wanjing Zhang Qianchen Zhou Xiaojun Zheng Qi Wang Zhengwei Fu Haifeng Li | 2018 | Acta Biochimica et Biophysica Sinica2018，50，3： | 3 |
| 18 | Enhancing sensing capacity of terahertz metamaterial absorbers with a surface-relief design显示文摘Metamaterial absorbers(MAs)serve as important electromagnetic wave-absorbing devices that have captured the attention of researchers for a long term.Functioning as sensitive detectors to determine perturbations in an ambient environment is another significant subsidiary function.Here,we theoretically propose an optimized fabrication method to implement terahertz MAs with fewer steps and also evaluate both absorption and sensing performances of such MAs realized by the new method.Simulation findings demonstrate that such MAs can basically maintain the original absorption features perfectly,including near-complete absorption at resonance as well as strong robustness to wide incident angles.Specifically,the full width at half-maximum and quality factor of the absorption resonances attenuate less than 26%and 8%with this new method,remaining in the ranges of^0.03–0.04 THz and^20–27 for two selected example MAs.More significantly,sensing capacities of this type of MA,in terms of maximum detection range(enhancing at least 9%),observable spectral modulation(increasing at least 6.3%),and refractive index sensitivity,are improved to a large extent because of more intense coupling between resonant field and matter in the case of surface-relief MAs.This stronger coupling results from exposing more spots of the resonantly high field to direct contact with an approaching analyte,which is illustrated by field profiles of the MAs at resonance in this work.Additionally,other desirable absorber features are also explored with such MAs,like functioning as building blocks to configure multiband MAs and strong robustness against fabrication errors.Such new-style terahertz MAs shown in the paper,acting as good examples,not only prove that terahertz MAs can be fabricated by the proposed time-and cost-saving route in contrast to the traditional MA fabrication process,but also can serve as novel platforms to explore other intriguing terahertz photonic effects,such as the field enhancement effect. | WEI WANG FENGPING YAN SIYU TAN HAISU LI XUEMEI DU LUNA ZHANG ZHUOYA BAI DAN CHENG HONG ZHOU YAFEI HOU | 2020 | Photonics Research2020，8，4： | 3 |
| 19 | Linking temporal records显示文摘许多数据集合包含跨越时间的一个长时期的时间的记录;每个记录与一枚时间邮票被联系并且在一特别时间描述一个真实世界的实体的一些方面(例如,在 DBLP 的作者信息) 。在如此的情况中,我们经常希望鉴别随着时间的过去并且那么描述一样的实体的记录能执行有趣的纵的数据分析。然而,存在记录连接技术忽略时间的信息并且突然相信时间的数据。这篇文章学习连接时间的记录。首先,我们使用时间腐烂在实体价值进化上捕获过去的时间的效果。而不是局部地比较每个记录,第二,我们求婚聚类考虑记录的时间顺序并且做全球决定的方法。试验性的结果证明我们的算法显著地在各种各样的时间的数据集合上超过传统的连接方法。 | Pei LI Xin Luna DONG Andrea MAURINO Divesh SRIVASTAVA | 2012 | Frontiers of Computer Science2012，6，3： | 3 |
| 20 | Impact of double helical CT and three-dimensional CT arteriography on surgical planning for hepatic transplantation显示文摘 | H. V. Nghiem C. T. Dimas J. P. McVicar J. D. Perkins J. A. Luna T. C. Winter III A. Harris P. C. Freeny | 1999 | Abdominal Imaging1999，，3： | 2 |
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