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| 1 | Vasculogenic mimicry is a prognostic factor for postoperative survival in patients with glioblastoma显示文摘A previous report has confirmed the existence and clinical significance of vasculogenic mimicry(VM)in glioma.However,its conclusions about the negative clinical significance of VM in glioblastoma are based on a small group of patients and,thus,might be unconvincing.The aim of the present study was to reevaluate the clinical significance of VM in glioblastoma.Patients were classified as VM-positive or | Wang SY Ke YQ Lu GH Song ZH Yu L Xiao S Sun XL Jiang XD Yang ZL Hu CC | 2013 | 中国神经肿瘤杂志2013，11，3： | 22 |
| 2 | Optical observations of LIGO source GW 170817 by the Antarctic Survey Telescopes at Dome A,Antarctica显示文摘The LIGO detection of gravitational waves(GW) from merging black holes in 2015 marked the beginning of a new era in observational astronomy. The detection of an electromagnetic signal from a GW source is the critical next step to explore in detail the physics involved. The Antarctic Survey Telescopes(AST3),located at Dome A, Antarctica, is uniquely situated for rapid response time-domain astronomy with its continuous night-time coverage during the austral winter. We report optical observations of the GW source(GW 170817) in the nearby galaxy NGC 4993 using AST3. The data show a rapidly fading transient at around 1 day after the GW trigger, with the i-band magnitude declining from 17:23 ± 0:13 magnitude to 17:72 ± 0:09 magnitude in ~1:8 h. The brightness and time evolution of the optical transient associated with GW 170817 are broadly consistent with the predictions of models involving merging binary neutron stars. We infer from our data that the merging process ejected about ~10^(-2) solar mass of radioactive material at a speed of up to 30% the speed of light. | lei hu xuefeng wu igor andreoni michael c.b.ashley jeff cooke xiangqun cui fujia du zigao dai bozhong gu yi hu haiping lu xiaoyan li zhengyang li ensi liang liangduan liu bin ma zhaohui shang tianrui sun n.b.suntzeff charling tao syed a.uddin lifan wang xiaofeng wang haikun wen di xiao jin xu ji yang shihai yang xiangyan yuan hongyan zhou hui zhang jilin zhou zonghong zhu | 2017 | Science Bulletin2017，62，21： | 6 |
| 3 | EXPERIMENTAL INVESTIGATION AND COMPUTER SIMULATION ON DYNAMIC BUCKLING BEHAVIOR OF LIQUID-FILLED CYLINDRICAL SHELLS UNDER AXIAL IMPACT显示文摘This article reports an experimental investigation on the axial impact buckling of thin metalliccylindrical shells fully filled with water.Low velocity impact tests are carried out by DHR-9401 drop hammerrig.The whole process of dynamic buckling is simulated using LS-DYNA computer code.The consistencybetween experimental observation and numerical simulation is quite satisfactory.The investigation indieatesthat quite high internal hydrodynamic pressure occurs inside the shell during the impact process.Under thecombined action of the high internal pressure and axial compression plastic buckling occurs easily in the thin-walled shells and buckling modes take on regular and axisymmetric wrinkles. | Zhang, SY Lei, JP Zhao, LM Cheng, GQ Lu, GY | 2000 | Acta Mechanica Solida Sinica2000，13，2： | 2 |
| 4 | Structural Comparison and Drug Screening of Spike Proteins of Ten SARS-CoV-2 Variants显示文摘SARS-CoV-2(severe acute respiratory syndrome coronavirus 2)has evolved many variants with stronger infectivity and immune evasion than the original strain,including Alpha,Beta,Gamma,Delta,Epsilon,Kappa,lota,Lambda,and 21H strains.Amino acid mutations are enriched in the spike protein of SARS CoV-2.which plays a crucial role in cell infetion.However,the impact of these mutations on protein structure and function is unclear.Understanding the pathophysiology and pandemic feaures of these SARS-CoV-2 variants requires knowledge of the spike protein structures.Here,we obtained the spike protein structures of 10 main globally endemic SARS CoV-2 strains using AlphaFold2.The clustering analysis based on structural similarity revealed the unique features of the mainly pandemic SARS CoV-2 Delta variants.indicating that structural clusters can reflect the current characteristics of the epidemic more accurately than those based on the protein sequence.The analysis of the binding afinities of ACE2-RBD,antibody-NTD,and antibody-RBD complexes in the different variants revealed that the recognition of antibodies against SI NTD and RBD was decreased in the variants,especally the Delta variant compared with the original strain,which may induce the immune evasion of SARS-CoV-2 variants.Furthermore,by virtual screening the ZINC database against a high-accuracy predicted structure of Delta spike protein and experimental validation,we identified multiple compounds that target S1 NTD and RBD,which might contribute towards the development of clinical anti-SARS-CoV-2 medicines.Our findings provided a basic foundation for future in vitro and in vivo investigations that might speed up the development of potential therapies for the SARS-CoV-2 va riants. | Qiangzhen Yang Xuemin Jian Ali Alamdar Shah Syed Aamir Fahira Chenxiang Zheng zijia Zhu Ke Wang Jinmai Zhang Yangin Wen Zhiqiang Li Dun Pan Tingting Lu Zhuo Wang Yongyong Shi | 2022 | Research2022，，2： | 2 |
| 5 | The 'stone-like' pattern of LC3A expression and its elinicopathologic significance in hepato-cellular carcinoma显示文摘 | Xi SY Lu JB Chen JW | 2013 | Biochem Biophys Res Commun2013，431，4： | 1 |
| 6 | Bupivacaine induces reactive oxy- gen species production via activation of the AMP-activated pro- tein kinase-dependent pathway显示文摘 | Lu J Xu SY Zhang QO | 2011 | Pharmacology2011，87，34： | 1 |
| 7 | Outcome of intensive integrated intervention in participants with impaired glucose regulation in China显示文摘 | Lu YH Lu JM Wang SY | 2011 | Adv Ther2011，28，6： | 1 |
| 8 | The effect of miR-7 on behavior and global protein expression in glioma cell lines显示文摘 | Lu ZJ Liu SY Yao YQ | | 0，，： | 1 |
| 9 | Cerebrospinal Fluid Markers of Alzheimer' s Disease Pathology and Microglial Activation are Associated with Ahered White Matter Microstructure in Asymptomatic Adults at Risk for Alzheimer' s Disease显示文摘 | Melah KE Lu SY Hoscheidt SM | 2015 | J Alzheirners Dis2015，50，3： | 1 |
| 10 | Changes in extratempo- ral integrity and cognition in temporal lobe epilepsy: a dif- fusion tensor imaging study 显示文摘 | Wang XQ Lang SY Hong LU | 2010 | Neurol India2010，58，6： | 1 |
| 11 | Interaction of Heliothis armigera nuclear polyhedrosis viral capsid protein with its host actin显示文摘 | Lu SY Qi Y P Ge G Q | 2002 | J Biochem Mol Biol2002，35，6： | 1 |
| 12 | Effectiveness of interventions for hypeen- sion care in the community-a meta-analvsis of controlled studies in China 显示文摘 | LU ZX Cao SY Chai Y | 2012 | BMC Healh Serv Res2012，12，： | 1 |
| 13 | Hydroxysafflor yellow A suppresses inflammatory responses of BV2 microglia after xygen-glucose deprivation显示文摘 | Li J Zhang SY Lu M | 2013 | Neuroscience Letters2013，535，： | 1 |
| 14 | Post-conditioning protects car- diomyocytes from apoptosis via PKC-interacting with calcium-sens- ing receptors to inhibit endo (sarco)plasmic reticulum-mitochondria crosstalk显示文摘 | Dong SY Teng ZY Lu FH | 2010 | Mol Cell Biochem2010，341，： | 1 |
| 15 | Related Articles, Links A clinical study of endodontic flare- ups 显示文摘 | Yeh SJ Lin YT Lu SY | 1994 | Changgeng Yi Xue Za Zhi1994，17，2： | 1 |
| 16 | Superantigen-SEB gene modified tumor vaccine for hepatocellular carcinoma:an in vitro study显示文摘 | Lu SY SUI YF LI ZS | 2004 | World J Gastroenterol2004，10，： | 1 |
| 17 | Endocrine-disrupting activity in carbendazim-induced reproductive and developmental toxicity in rats 显示文摘 | Lu SY Liao JW Kuo ML | 2004 | J Toxicol Environ Health A2004，67，： | 1 |
| 18 | Syk tyrosine kinase mediates Epstein-Barr virus latent membrane protein 2A-induced cell migration in epithelial cells显示文摘 | Lu J Lin WH Chen SY | 2006 | J Biol Chem2006，281，： | 1 |
| 19 | Dioxins and their fingerprint in size- classified fly ash fractions from municipal solid waste incinerators in China:mechanical grate and fluidized bed units 显示文摘 | Lu SY Du Y Yan J H et ol | 2012 | J Air Waste Manag Assoe2012，62，6： | 1 |
| 20 | Striatal,ven-tral mesencephalic and cortical transplants into the in-tact rat striatum:A neuroanato mical study显示文摘 | Lu SY Shiplesy MT Norman AB | 1991 | Exp Neurol1991，113，： | 1 |
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