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| 1 | Transcriptome analyses of the Dof-like gene family in grapevine reveal its involvement in berry, flower and seed development显示文摘The Dof(DNA-binding with one finger)protein family spans a group of plant transcription factors involved in the regulation of several functions,such as plant responses to stress,hormones and light,phytochrome signaling and seed germination.Here we describe the Dof-like gene family in grapevine(Vitis vinifera L.),which consists of 25 genes coding for Dof.An extensive in silico characterization of the VviDofL gene family was performed.Additionally,the expression of the entire gene family was assessed in 54 grapevine tissues and organs using an integrated approach with microarray(cv Corvina)and real-time PCR(cv Pinot Noir)analyses.The phylogenetic analysis comparing grapevine sequences with those of Arabidopsis,tomato,poplar and already described Dof genes in other species allowed us to identify several duplicated genes.The diversification of grapevine DofL genes during evolution likely resulted in a broader range of biological roles.Furthermore,distinct expression patterns were identified between samples analyzed,corroborating such hypothesis.Our expression results indicate that several VviDofL genes perform their functional roles mainly during flower,berry and seed development,highlighting their importance for grapevine growth and production.The identification of similar expression profiles between both approaches strongly suggests that these genes have important regulatory roles that are evolutionally conserved between grapevine cvs Corvina and Pinot Noir. | Danielle Costenaro da Silva Vítor da Silveira Falavigna Marianna Fasoli Vanessa Buffon Diogo Denardi Porto Georgios Joannis Pappas Jr Mario Pezzotti Giancarlo Pasquali Luís Fernando Revers | 2016 | Horticulture Research2016，3，1： | 5 |
| 2 | Comparison of gene expression between normalcolon mucosa and colon carcinoma by means of messenger RNA differential display显示文摘 | Wang L Lu W Chen YG Zhou XM Gu JR | 1999 | World Journal of Gastroenterology1999，5，6： | 4 |
| 3 | Study on incisional implantation of tumor cells by carbon dioxide pneumoperitoneum in gastric cancer of a murine model显示文摘 | Wang H Zheng MH Zhang HB Zhu J He JR Lu AG Ji YB Zhang MJ Jiang Y Yu BM Li HW | 1999 | World Journal of Gastroenterology1999，5，6： | 2 |
| 4 | TSC1-mTOR-PLK轴以阶段特异性方式调节从施旺细胞增殖到髓鞘形成的内稳态开关显示文摘恰如其分的外周髓鞘形成取决于雪旺细胞增殖与分化进程间的平衡。丝氨酸/苏氨酸激酶(mTOR)整合多种环境因素,是细胞生长、代谢、发挥作用的中枢调节者。本文报道了一种mTOR的负性调节剂——结节性硬化复合体(TSC1),通过控制细胞增殖和髓鞘稳态,建立了雪旺细胞谱系进展和髓鞘形成的阶段依赖性程序。小鼠雪旺细胞祖细胞中TSC1的解离导致mTOR信号通路激活,继而导致雪旺细胞过量增殖,分化受阻,髓鞘形成减少。转录组分析显示,TSC1突变体中的mTOR活化使得polo样激酶(PLK)依赖性通路和细胞周期调节剂上调。弱化mTOR或者对PLK进行药理抑制部分挽救了因TSC1缺失导致的外周神经发育过程中的髓鞘形成减少。相较之下,成年小鼠成熟雪旺细胞中TSC1缺失可导致髓鞘的过度增殖和过度生长。本文的发现提示了TSC1-mTOR-PLK信号轴在控制雪旺细胞的发育过程中,从增殖到分化和髓鞘内稳态中起到的阶段特异性功能。 | Jiang M Rao R Wang J Wang J1 Xu L Wu LM Chan JR Wang H Lu QR 聂昊(编译) | 2018 | 神经损伤与功能重建2018，13，5： | 2 |
| 5 | Virus - induced gene silencing in plants 显示文摘 | Lu R Martin - Hemandez AM Peart JR | 2003 | Methods2003，30，： | 1 |
| 6 | Power - efficient relay selection in cooperative networks using decentralized distributed space -time block coding显示文摘 | ZHANG Lu Leonard J Cimini Jr | 2008 | EURASIP Journal on Advances in Signal Processing2008，，9： | 1 |
| 7 | Control Charts for Monitoring the Mean and Variance of Autocorrelated Processes显示文摘 | LU C W REYNOLDS M R Jr | 1999 | Journal of Quality Technology1999，，31： | 1 |
| 8 | Isolation and character- ization of a Lactobacillus plantarum bacteriophage, ~JL-1, from a cucumber fermentation显示文摘 | Lu Z Breidt Jr F Fleming H | 2003 | Int J Food Microbiol2003，84，2： | 1 |
| 9 | Bioabsorbable anterior cer- vical plating: initial multicenter clinical and radiographic experience 显示文摘 | Aryan HE Lu DC Acosta Jr FL | 2007 | Spine2007，32，10： | 1 |
| 10 | A calcineurin-dependent transcriptional pathway forcardiac hypertrophy显示文摘 | Molkentin JD Lu JR Antos CL | 1998 | Cell1998，93，： | 1 |
| 11 | Anterior cruciate ligament regeneration using braided biodegradable scaffolds:in vitro optimization studies显示文摘 | Cooper Jr J A | 2005 | Biomaterials2005，26，： | 1 |
| 12 | Multiparametric interative self-organizing MR imaging data analysis technique for assessment of tissue viability in acute cerebral ischemia显示文摘 | Mitsias PD Ewing JR Lu M | 2004 | AJNR2004，25，9： | 1 |
| 13 | Shape memory alloy/ glass composite seal for solid oxide electrolyzer and fuel cells显示文摘 | Story C Lu K Reynolds Jr W T | 2008 | International Journal of Hydrogen Energy2008，33，14： | 1 |
| 14 | Evidence for type Ⅱ cells as cells of origin of K-Ras-induced distal lung adenocarcinoma 显示文摘 | Xu X Rock JR Lu Y | 2012 | Proc Natl Acad Sci U S A2012，109，13： | 1 |
| 15 | Advances in GML for geospatial applications显示文摘 | Lu C T Dos Santos Jr R F Sripada L N | 2007 | Journal of Computer Applications Geoinformatica2007，11，： | 1 |
| 16 | Requirement of the MADS-box transcription factor MEF2C for vascular development显示文摘 | Lin Q Lu JR Yanagisawa H | 1998 | Development1998，125，22： | 1 |
| 17 | A calcineurin dependent transcriptional pathway for cardiac hypertorphy显示文摘 | Molkentin JD Lu JR Antos CL | 1998 | Ceu1998，93，2： | 1 |
| 18 | An investigation of the chemiluminescence reaction in the sodium sychlorite-folic acid-emicarbazide hydrochloride system显示文摘 | Nie F He YH Lu JR | 2000 | Microchemical Journa2000，65，3： | 1 |
| 19 | Diffusive reequilibration of melt and fluid inclusions显示文摘 | Qin Z Lu F Anderson A T JR | 1992 | Am Mineral1992，77，： | 1 |
| 20 | Multiparametric iterative selforganizing MR imaging data analysis technique for assessment of tissue viability in acute cerebral ischemia显示文摘 | Mitsias DP Ewing JR Lu M | 2004 | AJNR2004，25，9： | 1 |
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