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| 1 | Prophylactic transcatheter arterial embolization reduces rebleeding in non-variceal upper gastrointestinal bleeding: A meta-analysis显示文摘BACKGROUND Despite the improvement in the endoscopic hemostasis of non-variceal upper gastrointestinal bleeding(NVUGIB),rebleeding remains a major concern.AIM To assess the role of prophylactic transcatheter arterial embolization(PTAE)added to successful hemostatic treatment among NVUGIB patients.METHODS We searched three databases from inception through October 19th,2020.Randomized controlled trials(RCTs)and observational cohort studies were eligible.Studies compared patients with NVUGIB receiving PTAE to those who did not get PTAE.Investigated outcomes were rebleeding,mortality,reintervention,need for surgery and transfusion,length of hospital(LOH),and intensive care unit(ICU)stay.In the quantitative synthesis,odds ratios(ORs)and weighted mean differences(WMDs)were calculated with the random-effects model and interpreted with 95%confidence intervals(CIs).RESULTS We included a total of 3 RCTs and 9 observational studies with a total of 1329 patients,with 486 in the intervention group.PTAE was associated with lower odds of rebleeding(OR=0.48,95%CI:0.29–0.78).There was no difference in the 30-d mortality rates(OR=0.82,95%CI:0.39–1.72)between the PTAE and control groups.Patients who underwent PTAE treatment had a lower chance for reintervention(OR=0.48,95%CI:0.31–0.76)or rescue surgery(OR=0.35,95%CI:0.14–0.92).The LOH and ICU stay was shorter in the PTAE group,but the difference was non-significant[WMD=-3.77,95%CI:(-8.00)–0.45;WMD=-1.33,95%CI:(-2.84)–0.18,respectively].CONCLUSION PTAE is associated with lower odds of rebleeding and any reintervention in NVUGIB.However,further RCTs are needed to have a higher level of evidence. | Eszter Boros Zoltán Sipos Péter Hegyi Brigitta Teutsch Levente Frim Szilárd Váncsa Szabolcs Kiss FanniDembrovszky Eduard Oštarijaš Andrew Shawyer Bálint Erőss | 2021 | World Journal of Gastroenterology2021，27，40： | 2 |
| 2 | Influence of temperature, humidity and defect location on ddamination in plastic IC packages 显示文摘 | TAY A A O LINT Y | 1999 | IEEE Trans Compon Packg Technol1999，22，4： | 1 |
| 3 | Market entry,phased rollout or abandonment? A real option approach显示文摘 | Penning E Lint O | 2000 | European Journal of Operational Research2000，124，1： | 1 |
| 4 | Market entry,phased rollout or abandonment? A real option approach显示文摘 | Pennings E Lint O | 2000 | European Journal of Operational Research2000，124，1： | 1 |
| 5 | Market entry, phased rollout or abandonment? A real option approach显示文摘 | PENNINGS E LINT O | 2000 | European Journal of Operational Reseach2000，，124： | 1 |
| 6 | An option approach to the new product development process :a case study at phillips electronics 显示文摘 | Lint O Pennings E | 2007 | R&D Management2007，31，2： | 1 |
| 7 | Developing an integrated framework for feature-based early manufacturing cost estimation显示文摘 | YANG C O LINT S | 1997 | International Journal of Manufacturing Technology1997，13，9： | 1 |
| 8 | The recently chosen digital video standard:playing the game within the game显示文摘 | Pennings E | 2003 | Technovation2003，23，4： | 1 |
| 9 | The option value of advanced R&D显示文摘 | Pennings E Lint O | 1997 | European Journal of Operational Research1997，103，： | 1 |
| 10 | Molecular cloning and charac- terization of a novel transglutaminase cDNA from a hu- man prostate cDNA library显示文摘 | Grant F J Taylor D A Sheppard P O Mathewes S L Lint W Vanaja E | 1994 | Biochem Biophys Res Commun1994，203，： | 1 |
| 11 | Market entry,phased roll out or abandonment? A real option approach显示文摘 | PENNINGS E LINT O | 2000 | Euro J Operational Res2000，124，： | 1 |
| 12 | The option value of advanced R&D显示文摘 | Pennings E Lint O | 1997 | European Journal of Operational Research1997，103，： | 1 |
| 13 | Market entry,phased rollout or abandonment? A real option approach显示文摘 | Pennings E Lint O | 2000 | European Journal of Operational Research2000，，124： | 1 |
| 14 | Market entry, phased rollout or abandonment? a real option approach 显示文摘 | Pennings E Lint O | 2000 | European Journal of Operational Research2000，124，： | 1 |
| 15 | Effects of humic substance characteristics on UF performance显示文摘 | LIN C F LINT Y HAO O J | 2000 | Wat Res2000，34，4： | 1 |
| 16 | R&D as an option on market introduction 显示文摘 | Lint O Pennings E | 1998 | R&D Management1998，，4： | 1 |
| 17 | R&D as an option on market introduction显示文摘 | Lint O Pennings E | 1998 | R&D Management1998，28，： | 1 |
| 18 | Effects of humic substance characteristics on LTF performance显示文摘 | LIN C F LINT Y HAO O J | 2000 | Water Research2000，34，4： | 1 |
| 19 | Market entry, phased rollout or abandonment? A real option approach 显示文摘 | Pennings E Lint O | 2000 | European Journal of Operational Research2000，124，1： | 1 |
| 20 | R&D as an option on markct introduction 显示文摘 | Lint O Pennings E | 1998 | R & D Management1998，28，： | 1 |
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