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96篇 您的检索式:作者名="LINDLEY S"
    题名 作者 年代 出处 被引量
1Streptozotocin-induced type 1 diabetes mel itus alters the morphology,secretory function and acyl lipid contents in the isolated rat parotid salivary gland显示文摘Mahay S Adeghate E Lindley MZ 0,,1:1
2Characterisation and transplantation of enteric nervous system progenitor cells 显示文摘Almond S Lindley RM Kenny SE 2007Gut2007,56,:1
3Characteristics,management and response to alteplase in China versus non-China participants of the ENCHANTED trial显示文摘Background The characteristics of patients with acute ischaemic stroke(AIS)and their management vary across regions,which may influence outcomes.We examined for differential patterns of outcome between China and non-China participants of the ENhanced Control of Hypertension And Thrombolysis strokE stuDy(ENCHANTED),which tested different alteplase doses in AIS.Methods ENCHANTED was an international,multicentre,open,blinded-endpoint trial of the effects of low-dose(0.6 mg/kg)versus standard-dose(0.9 mg/kg)intravenous alteplase on 90-day disability outcomes and symptomatic intracerebral haemorrhage(sICH)in 3310 patients with AIS.Results Participants(n=1419,48%)in China were younger,and more often male,hypertensive and with prior stroke and coronary artery disease,but less likely to have atrial fibrillation and use antihypertensive,antithrombotic and lipid-lowering agents,compared with non-China patients with AIS.Although China participants had more AIS due to large artery occlusion,were treated later and had differing ancillary management,there was no significant difference in 90-day modified Rankin scale scores 2–6(55.6% vs 47.8%;OR,adjusted for baseline and management factors 0.87(95%CI 0.71 to 1.07;p=0.20))and risk of sICH(Safe Implementation of Thrombolysis in Stroke-Monitoring Study criteria:1.4% vs 1.8%;p=0.12)compared with non-China participants.There was no heterogeneity in the treatment effects of low-dose versus standard-dose alteplase between China and non-China participants.Conclusion Patients with AIS recruited to the ENCHANTED trial in China had similar outcomes in response to thrombolysis treatment despite significantly differing demographic,clinical and management factors to patients with AIS in other regions.Lily Song Xia Wang Thompson Robinson Richard I Lindley Hisatomi Arima Pablo M Lavados Xiaoying Chen John Chalmers Craig S Anderson 2017Stroke & Vascular Neurology2017,2,2:1
4Defective suppressor function in CD4^+ CD25^+ T cells from patients with type 1 diabetes显示文摘Lindley S Dayan CM Bishop A 2005Diabetes2005,54,1:1
5Urban particulatepollution reduction by four species of green roof vegetation in aUK city显示文摘Speak A F Rothwell J J Lindley S J al 2012Atmospheric Environment2012,61,:1
6Regulation of eytoehrome P450 2C9 expression in primary cultures of human hepatoeytes显示文摘Sahi J Shord S S Lindley C 2009J Biochem Mol Toxicol2009,23,1:1
7Abilities and skill in basketball显示文摘Starkes J Allard F Lindley S & O'Reilly K 1994International Journal of Sport Psychology1994,25,:1
8Cerebral autoregulation and CO2 reactivity in anterior and posterior cerebral circulation during sevoflurane anesthesia 显示文摘Rozet I Vavilala M S Lindley A M 2006Anesth Analg2006,102,2:1
9CagA/eytotoxie strains of Helieobacter pylori and interleukin - 8 in gastric epithelial cell lines显示文摘Crabtree J E Farmery S M Lindley I J D 1994J ClinPatho1994,47,:1
10Characterisation and transplantation of enteric nervous system progenitor cells显示文摘Almond S Lindley RM Kenny SE 2007Gut2007,56,4:1
11Defective suppressor function in CD4^+ CD25^+ T-cells from patients with type 1 diabetes显示文摘Lindley S Dayan C M Bishop A 2005Diabetes2005,54,1:1
12Dynamic Response of Catabolic Pathways to Autoacidification in Lactococcus lactis: Transcript Profiling and Stability in Relation to Metabolic and Energetic Constraints显示文摘EVEN S LINDLEY N D LOUBIERE P 2002Mol Microbiol2002,45,:1
13Long-term variability in the diversity of North Sea zooplankton显示文摘Lindley J A Batten S D 2002Journal of the Marine Biological Association of the UK2002,82,01:1
14Ondansetron, prochlorpera- zine, and dexamethasone have similar effects on prevention of de-layed chemotherapy - induced nausea and vomiting 显示文摘Lindley C Goodin S McCune J 2006Cancer Treatment Reviews2006,32,:1
15Aspects of Equivalence between Contact Mechanics and Fracture Mechanics:Theoretical Connections and a Life Prediction Methodology for Fretting-fatigue显示文摘Giannakopoulos A E Lindley T C Suresh S 1998Acta Material1998,46,:1
16Prevention of delayed chemotherapy-induced nausea and vomiting after moderately high to highly emetogenic chemotherapy: comparison of ondansetron, prochlorperazine and dexamethasone 显示文摘Lindley C Goodin S McCune J 2005Am J Clin Oncol2005,28,3:1
17Lumbar spinal fusion ver sus anterior lumbar disc replacement:the financial implications显示文摘Patel VV Estes S Lindley EM 2008J Spinal Disord Tech2008,21,7:1
18Smoking influences outcome in patients who had thrombolysed ischaemic stroke:the ENCHANTED study显示文摘Background and purpose As studies vary in defining the prognostic significance of smoking in acute ischaemic stroke(AIS),we aimed to determine the relation of smoking and key outcomes in patient participants who had thrombolysed AIS of the international quasi-factorial randomised Enhanced Control of Hypertension and Thrombolysis Stroke Study(ENCHANTED).Methods Post-hoc analyses of ENCHANTED,an international quasi-factorial randomised evaluation of intravenous alteplase-dose comparison and levels of blood pressure control in patients who had thrombolysed AIS.Multivariable logistic regression models with inverse probability of treatment weighting(IPTW)propensity scores were used to determine associations of self-reported smoking status and clinical outcomes,according to 90-day modified Rankin Scale(mRS)scores and symptomatic intracerebral haemorrhage(sICH).Results Of 4540 patients who had an AIS,there were 1008(22.2%)current smokers who were younger and predominantly male,with more comorbidities of hypertension,coronary artery disease,atrial fibrillation and diabetes mellitus,and greater baseline neurological impairment,compared with non-smokers.In univariate analysis,current smokers had a higher likelihood of a favourable shift in mRS scores(OR 0.88,95%CI 0.77 to 0.99;p=0.038)but this association reversed in a fully adjusted model with IPTW(adjusted OR 1.15,95%CI 1.04 to 1.28;p=0.009).A similar trend was also apparent for dichotomised poor outcome(mRS scores 2–6:OR 1.18,95%CI 1.05 to 1.33;p=0.007),but not with the risk of sICH across standard criteria.Conclusion Smoking predicts poor functional recovery in patients who had thrombolysed AIS.Trial registration number NCT01422616.Lingli Sun Lili Song Jie Yang Richard I Lindley Thompson Robinson Pablo M Lavados Candice Delcourt Hisatomi Arima Bruce Ovbiagele John Chalmers Craig S Anderson Xia Wang 2021Stroke & Vascular Neurology2021,6,3:1
19Testing the iron hypothesis in ecosystems of the equatorial Pacific Ocean 显示文摘Martin J H CoMe K H Johnson K S Fitzwater S E Gordon R M Tanner S J Hunter C N Elrod V A Nowicki J L Coley T L Barber R T Lindley S Watson A J Van Scoy K Law C S Liddicoat M I Ling R Stanton T Stoekel J Collins C Anderson A Bidigare R Ondrusek M Latasa M Millero F J Lee K Yao W Zhang J Z Friederich G Sakamoto C Chavez F Buck K Kolber Z Greene R Falkowski P Chisholm S W Hoge F Swift R Yangel J Turner S Nightingale P Hatton A Liss P Tindale N W 1994Nature1994,371,6493:1
20Probabilistic GIS- based method for delineation of urban flooding risk hotspots显示文摘JALAYER F DE RISI R DE PAOLA F GIUGNI M MANFREDI G GASPAR1NI P TOPA M E YONAS N YESHITELA K NEBEBE A CAVAN G LINDLEY S PRINTZ A RENNER F 2014Natural Hazards2014,73,2:1
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