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| 1 | 中、重度一氧化碳中毒所致心肌损伤与远期死亡率显示文摘背景:一氧化碳(carbon monoxide,CO)中毒是常见的导致中毒和死亡的原因。心肌损伤为中、重度CO中毒的常见后遗症。此类患者的住院死亡率较低,但是有关心肌损伤的远期结局如何仍属未知。 | Christopher R. Henry Daniel Satran Bruce Lindgren 李呈亿(译) | 2006 | 美国医学会杂志(中文版)2006，25，6： | 17 |
| 2 | Probabilistic routing in intermittently connected networks显示文摘 | Anders Lindgren Avri Doria Olov Schelén | 2003 | ACM SIGMOBILE Mobile Computing and Communications Review2003，，3： | 4 |
| 3 | Cerebral venous thrombosis and heparin-induced thrombocytopenia in an 18-year old male with severe ulcerative colitis显示文摘The risk of thromboembolism is increased in inflammatory bowel disease and its symptoms may be overlooked. Furthermore, its treatment can be complex and is not without complications. We describe a case of an adolescent boy who developed a cerebral sinus venous thrombosis during a relapse of his ulcerative colitis and who, while on treatment with heparin, developed heparin-induced thrombocytopenia (HIT). The treatment was then switched to fondaparinux, a synthetic and selective inhibitor of activated factor . | Gudrun Scheving Thorsteinsson Maria Magnussson Lena M Hallberg Nils Gunnar Wahlgren Fredrik Lindgren Petter Malmborg Thomas H Casswall | 2008 | World Journal of Gastroenterology2008，14，28： | 4 |
| 4 | Efficacy and safety of granulocyte, monocyte/macrophage adsorptive in pediatric ulcerative colitis显示文摘AIM: To investigate efficacy and safety for granulocyte, monocyte apheresis in a population of pediatric patients with ulcerative colitis.METHODS: The ADAPT study was a prospective, openlabel, multicenter study in pediatric patients with moderate, active ulcerative colitis with pediatric ulcerative colitis activity index(PUCAI) of 35-64. Patients received one weekly apheresis with Adacolumn granulocyte, monocyte/macrophage adsorptive(GMA) apheresis over 5 consecutive weeks, optionally followed by up to 3 additional apheresis treatments over 3 consecutive weeks. The primary endpoint was the change in mean PUCAI between baseline and week 12; the secondary endpoint was improvement in PUCAI categorized as(Significant Improvement, PUCAI decrease of ≥ 35), Moderate Improvement(PUCAI decrease of 20 < 35), Small Improvement(PUCAI decrease of 10 < 20) or No change(PUCAI decrease of < 10). RESULTS: Twenty-five patients(mean age 13.5 years; mean weight 47.7 kg) were enrolled. In the intention-to-treat set(ITT), the mean value for PUCAI improvement was 22.3 [95%CI: 12.9-31.6; n = 21]. In the per-protocol(PP) set, the mean improvement was 36.3 [95%CI: 31.4-41.1; n = 8]. Significant Improvement was recorded for 9 out of 20 patients(45%); 5 out of 20 patients(25%) had Moderate Improvement and one patient(5%) had No Change in PUCAI score at week 12. In the PP set, six out of eight patients(75%) showed Significant Improvement; and in two out of eight patients(25%) Moderate Improvement was recorded. The endoscopic activity index(EAI) decreased by 3 points on average. Seven(7) out of 21(33%) patients in ITT and 4 out of 8(50%) patients in PP have used steroids during the clinical investigation. The mean steroid dosage for these patients in the ITT set decreased from a mean 12.4 mg to 10 mg daily on average from Baseline to week 12.CONCLUSION: Adacolumn; GMA apheresis treatment was effective in pediatric patients with moderate active Ulcerative Colitis. No new safety signals were reported. The present data contribute to considering GMA apheresis as a therapeutic option in pediatric patients having failed first line therapy. | Tarja Ruuska Peter Küster Lena Grahnquist Fredrik Lindgren Anne Vibeke Wewer | 2016 | World Journal of Gastroenterology2016，22，17： | 3 |
| 5 | 国际卒中遗传学联盟的推荐意见(第1部分):标准化表型数据收集显示文摘与几乎所有复杂疾病一样,卒中的患病风险和临床转归也是多基因作用的[1]。探索相关基因突变有望为新型个体化治疗方法奠定基础,从而显著减少卒中对全球健康造成的毁灭性影响。为了达到足够的统计学效能以确认多个风险性等位基因,需要很大的样本量。尽管卒中是全世界范围内第二大致死病因和成年人致残的主要原因[2],但没有任何一家研究机构能独立收集到足够的样本。在认识到这一挑战之后,来自世界各地的卒中研究者们于2007年成立了国际卒中遗传学联盟( International Stroke Genetics Consortium, ISGC; http://www. strokegenetics.org),其使命是通过研究在全球多个研究机构入组的患者来识别影响卒中患病风险、临床预后和治疗效果的遗传学因素。尽管先前已取得了一些成功[3-5],仍有大量工作有待进行,这不仅是为了发现风险性等位基因从而达到卒中个体化医疗的最终目标,更是为了开发综合性卒中风险评估手段以及得到足以改变临床实践的结果[6]。根据糖尿病和冠状动脉疾病等其他复杂疾病的研究进展,为了识别与卒中相关的所有基因突变,需要100000~200000个样本。为了达到这个样本量,需要进行更为广泛的协作。 | Jennifer J. Majersik John W.Cole Jonathan Golledge Natalia S. Rost Yu-Feng Yvonne Chan M. Edip Gurol Ame G. Lindgren Daniel Woo Israel Fernandez-Cadenas Donna T. Chen Vincent Thijs Bradford B. Worrall Ayeesha Kamal Paul Bentley Joanna M. Wardlaw Ynte M. Ruigrok Thomas W.K Battey Reinhold Schmidt Joan Montaner Anne-Katrin Giese Jaume Roquer Jordi Jimenez-Conde Chaeyoung Lee Hakan Ay Juan Jose Martin 李海峰 岳耀先 徐军 | 2015 | 国际脑血管病杂志2015，23，9： | 3 |
| 6 | Position and Velocity Estimation Via Bearings-only Observations 显示文摘 | Lindgren A G Gong K F | 1978 | IEEE Transactions on Aerospace and Electronic Systems1978，14，4： | 3 |
| 7 | 医生的继续职业发展是高质量医疗卫生服务的基础显示文摘对医生来说,学习是一个终身的过程。医生的职业发展始于医学院校,延续到行医生涯的结束。在整个职业生涯中,学习一直是医生日常工作中的重要组成部分。近年来,国际上继续医学教育无论从教育理论还是教育形式、内容等方面都随着科学技术的进步和卫生服务需求的提高而快速发展。世界医学教育联合会于2003年3月在丹麦哥本哈根召开的“医学教育的全球标准:为了更好的保健服务”的世界大会上,正式颁布了涵盖医学教育连续统一体的本科医学教育———毕业后医学教育———继续职业发展三个阶段的国际标准,构成了医学教育国际标准的三部曲。 | Stefan Lindgren | 2011 | 中国继续医学教育2011，3，1： | 2 |
| 8 | Productivity changes in Swedish pharamacies 1980–1989: A non-parametric Malmquist approach显示文摘 | R. F?re S. Grosskopf B. Lindgren P. Roos | 1992 | Journal of Productivity Analysis (-)1992，，12： | 2 |
| 9 | Coordination and conformation in PEO, PEGM and PEG systems containing lithium or lanthanum triflate显示文摘 | Annika Bernson Jan Lindgren | 1995 | Polymer1995，，23： | 2 |
| 10 | Hepatic and extrahepatic malignancies in primary sclerosing cholangitis显示文摘 | Annika Bergquist Anders Ekbom Rolf Olsson Dan Kornfeldt Lars L??f ?ke Danielsson Rolf Hultcrantz Stefan Lindgren Hanne Prytz Hanna Sandberg-Gertzén Sven Almer Fredrik Granath Ulrika Broomé | 2002 | Journal of Hepatology2002，，3： | 2 |
| 11 | Increased risk of cirrhosis and hepatocellular cancer during long-term follow-up of patients with biopsy-proven NAFLD显示文摘 | Kristina ? nnerhag Peter M Nilsson Stefan Lindgren | 2014 | Scandinavian Journal of Gastroenterology2014，，9： | 2 |
| 12 | 国际卒中遗传学联盟的推荐意见(第2部分):生物样本的采集和储存显示文摘在2003年人类基因组测序以及全基因组基因分型技术发展的共同促进下,人类遗传学的进步已使我们识别出2000多个与性状相关的基因突变。由于这些突变大多数对疾病风险仅有微小的独立影响,因此成功的遗传学研究需要很大的样本量(包含数以千计、万计或者十万计的病例和对照)才能达到足够的研究效能。如此大的样本量积累需要依赖在人类遗传学研究乃至在临床研究中史无前例的大规模国际协作。现在已有许多常见疾病的专病联盟将大量独立机构和合作者联合起来。每个联盟均面临至少2个基本问题:如何整合具有足够数量、同质性和表型质量高的研究样本以及如何储存和分析来自入组受试者的生物样本,有时可能需要在数年间反复进行。 | Thomas W.K.Battey Valerie Valant Sylvia Baedorf Kassis Christina Kourkoulis Chaeyoung Lee Christopher D. Anderson Guido J. Falcone Jordi Jimenez-Conde Israel Fernandez-Cadenas Guillaume Pare Tatjana Rundek Michael L. James Robin Lemmens Tsong-Hai Lee Turgut Tatlisumak Steven J. Kittner Arne Lindgren Farrah J. Mateen Aaron L. Berkowitz Elizabeth G. Holliday Jennifer Majersik 李海峰 姜平 岳耀先 | 2015 | 国际脑血管病杂志2015，23，9： | 2 |
| 13 | 病变广泛的轻/中度活动性溃疡性结肠炎患者接受美沙拉嗪口服和灌肠联合治疗优于单纯口服治疗:一项随机、双盲、安慰剂对照研究 | Marteau P. Probert C.S. Lindgren S. 赵菊辉 | 2005 | 世界核心医学期刊文摘(胃肠病学分册)2005，0，10： | 2 |
| 14 | Direct Electron Transfer Between Heme-Containing Enzymes and Electrodes asBasis for Third Generation Biosensors 显示文摘 | Gorton L Lindgren A Larsson T | 1999 | Anal Chim Acta1999，400，： | 2 |
| 15 | Acute myelogenous leukemia with t (6 ; 9 ) ( p23 ; q34 ) and marrow basophilia : an overview 显示文摘 | Chi Y Lindgren V Quigley S | 2008 | Arch Pathol Lab Med2008，132，11： | 1 |
| 16 | Incidence of intracerebral and subarachnoid hemorrhage in southern Sweden显示文摘 | Lindgren A Stahl N | 2000 | J Neurol Neurosurg Psychiatry2000，69，5： | 1 |
| 17 | Productivity changes in Swedish pharmacies 1980-1989:a non-parametric malmquist approach显示文摘 | GROSSKOPF LINDGREN ROSS | 1992 | Journal of Productivity Analysis1992，，3： | 1 |
| 18 | Using single family in reforestation: gene diversity concerns 显示文摘 | Kang K S Lai H L Lindgren D | 2002 | Silvae Genetica2002，51，23： | 1 |
| 19 | Dexmedetomidine at-tenuates sympathoadrenal responses to tracheal intubation andreduces the need for thiopentone and peroperative fentanyl显示文摘 | Scheinin B Lindgren L Randell T | 1992 | Br J Anaesth1992，68，2： | 1 |
| 20 | Tissue plasminogen activator and plasminogen activator inhibitor-1 in stroke patients 显示文摘 | Lindgren A Lindoff C Norrving B | 1996 | Stroke1996，27，6： | 1 |
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