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| 1 | Feeding of Riptortus pedestris on soybean plants, the primary cause of soybean staygreen syndrome in the Huang-Huai-Hai river basin显示文摘Staygreen syndrome or Zhengqing in soybean has recently become a major issue for Chinese growers in the Huang-Huai-Hai river basin.Although previous studies revealed that staygreen can be induced when pods/seeds are damaged, it is unknown whether virus infection or insect infestation causes staygreen.To determine whether viral infection causes staygreen, a survey of soybean staygreen incidence in the Huang-Huai-Hai river basin was conducted in 2016 and 2017.Diseased samples were collected and analyzed using DAS-ELISA for Soybean mosaic virus, Watermelon mosaic virus, Bean pod mottle virus, Cucumber mosaic virus, and Bean common mosaic virus.The survey showed that the severity of soybean staygreen syndrome was most prevalent in Beijing, Henan, Shaanxi, and some parts of Shandong provinces, with yield losses from 0 to nearly 100%, but only a small fraction of samples were positive for the tested viruses.A field cage experiment and an insecticide treatment field trial were conducted to determine the contribution of the bean bug, Riptortus pedestris, to staygreen incidence.The field cage experiment showed that R.pedestris treatment resulted in shorter plants, more empty pods, increased numbers of abnormal seeds, and decreased yields.The field experiment showed that there were fewer R.pedestris and less soybean staygreen incidence in fields treated with insecticide than in untreated control fields.Together, these results suggest that R.pedestris infestation rather than virus infection induces staygreen syndrome and that growers in this region can mitigate staygreen syndrome via bean bug control. | Kai Li Xinxin Zhang Jianqiu Guo Hannah Penn Tingting Wu Lin Li Hong Jiang Lidan Chang Cunxiang Wu Tianfu Han | 2019 | The Crop Journal2019，7，3： | 30 |
| 2 | Bias-drift-free Mach–Zehnder modulators based on a heterogeneous silicon and lithium niobate platform显示文摘Optical modulators have been and will continue to be essential devices for energy-and cost-efficient optical communication networks.Heterogeneous silicon and lithium niobate modulators have demonstrated promising performances of low optical loss,low drive voltage,and large modulation bandwidth.However,DC bias drift is a major drawback of optical modulators using lithium niobate as the active electro-optic material.Here,we demonstrate high-speed and bias-drift-free Mach–Zehnder modulators based on the heterogeneous silicon and lithium niobate platform.The devices combine stable thermo-optic DC biases in silicon and ultra-fast electro-optic modulation in lithium niobate,and exhibit a low insertion loss of 1.8 d B,a low half-wave voltage of 3 V,an electro-optic modulation bandwidth of at least 70 GHz,and modulation data rates up to 128 Gb/s. | SHIHAO SUN MINGBO HE MENGYUE XU SHENGQIAN GAO ZIYAN CHEN XIAN ZHANG ZILIANG RUAN XIONG WU LIDAN ZHOU LIN LIU CHAO LU CHANGJIAN GUO LIU LIU SIYUAN YU XINLUN CAI | 2020 | Photonics Research2020，8，12： | 5 |
| 3 | Severity of early allograft dysfunction following donation after circulatory death liver transplantation:a multicentre study显示文摘Background:Early allograft dysfunction(EAD)is associated with decreased graft and patient survival rates.This study aimed to identify the severity of EAD and develop a predictive model for EAD after donation after circulatory death(DCD)liver transplantation(LT).Furthermore,the influence of operative time on EAD incidence was also evaluated.Methods:In this retrospective,multicentre cohort study,nomograms were established based on a single-centre training cohort(n=321)and validated in a 3-center validation cohort(n=501).Results:The incidence rate of EAD was 46.4%(149/321)in the training cohort and 40.5%(203/501)in the validation cohort.Of the 149 EAD patients in the training cohort,77 patients with either elevated alanine aminotransferase(ALT)or aspartate aminotransferase(AST)were classified as having EAD type A,and the rest of the EAD patients were classified as having EAD type B.Recipients with EAD type B had lower graft and patient survival rates than recipients with EAD type A(P=0.043 and 0.044,respectively).We further developed a nomogram to predict EAD(graft weight,cold ischemia time,donor age,model for end-stage liver disease(MELD)score)and another nomogram to predict EAD type B(graft weight,cold ischemia time,MELD score).The nomograms for the prediction of EAD and EAD type B had good discrimination[concordance index(C-index)=0.712(0.666-0.758),0.707(0.641-0.773)]and calibration[Hosmer-Lemeshow(HL)P=0.384,P=0.425]in the validation cohort.An increased operative time(>6 h)was associated with increased EAD and EAD type B incidence in the high-risk group(P=0.005,P=0.020,respectively).Conclusions:EAD type B was associated with decreased graft and patient survival rates.The novel nomograms effectively predicted the incidence of EAD and EAD type B in DCD LT patients. | Kun Wang Di Lu Yuhui Liu Wangyao Li Li Zhuang Zhenyu Ma Qinfen Xie Binhua Pan Yichao Wu Junli Chen Lidan Lin Xiaowen Feng Qiang Wei Xuyong Wei Haiyang Xie Zhengxin Wang Shusen Zheng Xiao Xu | 2021 | Hepatobiliary Surgery and Nutrition2021，10，1： | 4 |
| 4 | Protective electrode/electrolyte interphases for high energy lithium-ion batteries with p-toluenesulfonyl fluoride electrolyte additive显示文摘High energy density lithium-ion batteries using Ni-rich cathode(such as LiNi0.6Co0.2Mn0.2O2) suffer from severe capacity decay.P-toluenesulfonyl fluoride(pTSF) has been investigated as a novel film-forming electrolyte additive to enhance the cycling performances of graphite/LiNi0.6Co0.2Mn0.2O2 pouch cell.In comparison with the baseline electrolyte,a small dose of pTSF can significantly improve the cyclic stability of the cell.Theoretical calculations together with experimental results indicate that pTSF would be oxidized and reduced to construct protective interphase film on the surfaces of LiNi0.6Co0.2Mn0.2O2 cathode and graphite anode,respectively.These S-containing surface films derived from pTSF effectively mitigate the decomposition of electrolyte,reduce the interphasial impedance,as well as prevent the dissolution of transition metal ions from Ni-rich cathode upon cycling at high voltage.This finding is beneficial for the practical application of high energy density graphite/LiNi0.6Co0.2Mn0.2O2 cells. | Yanxia Che Xiuyi Lin Lidan Xing Xiongcong Guan Rude Guo Guangyuan Lan Qinfeng Zheng Wenguang Zhang Weishan Li | 2021 | Journal of Energy Chemistry2021，30，1： | 3 |
| 5 | Revealing the critical effect of solid electrolyte interphase on the deposition and detriment of Co(Ⅱ) ions to graphite anode显示文摘'Dissolution,migration,and deposition'of transition metal ions (TMIs) result in capacity degradation of lithium-ion batteries (LIBs).Understanding such detrimental mechanism of TMIs is critical to the development of LIBs with long cycle life.In most previous works,TMIs were directly introduced into the electrolyte to investigate such a detrimental mechanism.In these cases,the TMIs are deposited directly on the fresh anode surface.However,in the practical battery system,the TMIs are deposited on the anode covered with solid electrolyte interphase (SEI) film.Whether the pre-presence of SEI film on anode surface influences the deposition and detriment of TMIs is unclear.In this work,the deposition of Co element on graphite anode with and without SEI film were systematically studied.The results clearly show that,in comparison with that of fresh graphite (SEI-free),the presence of SEI film aggravates the deposition of Co ions due to the Li^(+)–Co^(2+) ion exchange between the SEI and Co^(2+)-containing electrolyte without the driving of the electric field,leading to faster capacity fading of graphite anode.Therefore,how to regulate electrolytes and film-forming additives to design the components of SEI and prevent its exchange with TMIs,is a crucial way to inhibit the deposition and detriment of TMIs on graphite anode. | Qiming Xie Jiawei Chen Lidan Xing Xianggui Zhou Zekai Ma Binhong Wu Yilong Lin Hebing Zhou Weishan Li | 2022 | Journal of Energy Chemistry2022，31，6： | 2 |
| 6 | From Quigley the writer to Murphythe job seeker:Beckett’s evolving vision of char-acters and plots in Murphy显示文摘 | Lin Lidan | 2006 | English Studies2006，87，31： | 1 |
| 7 | Development of a dual temperature control system for isoprene biosynthesis in Saccharomyces cerevisiae显示文摘Conflict between cell growth and product accumulation is frequently encountered in the biosynthesis of secondary metabolites. To address the growth-production conflict in yeast strains harboring the isoprene synthetic pathway in the mitochondria, the dynamic control of isoprene biosynthesis was explored. A dual temperature regulation system was developed through engineering and expression regulation of the transcriptional activator Gal4p. A cold-sensitive mutant, Gal4ep19, was created by directed evolution of Gal4p based on an internally developed growth-based high-throughput screening method and expressed under the heat-shock promoter PSSA4 to control the expression of PGAL-driven pathway genes in the mitochondria. Compared to the control strain with constitutively expressed wild-type Gal4p, the dual temperature regulation strategy led to 34.5% and 72% improvements in cell growth and isoprene production, respectively. This study reports the creation of the first cold-sensitive variants of Gal4p by directed evolution and provides a dual temperature control system for yeast engineering that may also be conducive to the biosynthesis of other high-value natural products. | Jiaxi Lin Zhen Yao Xiaomei Lyu Lidan Ye Hongwei Yu | 2022 | Frontiers of Chemical Science and Engineering2022，16，7： | 1 |
| 8 | Improved electrochemical performance of LiNi 0.5 Mn 1.5 O 4 as cathode of lithium ion battery by Co and Cr co-doping显示文摘 | Dongrui Chen Benzhen Li Youhao Liao Hongwei Lan Haibin Lin Lidan Xing Yating Wang Weishan Li | 2014 | Journal of Solid State Electrochemistry2014，，7： | 1 |
| 9 | An improved keyframe extraction methed based on HSV colour space显示文摘 | ZHONG Q U LIN Lidan GAO Tengfei | 2013 | Journal of Software2013，8，7： | 1 |
| 10 | 组蛋白H3泛素化通过影响H3K9甲基化进而调控肝脏发育相关基因表达的机制显示文摘文章简介肝脏的发育是一个多步骤并且受到严格调控的过程。过去的研究主要集中在个体出生前肝细胞如何分裂分化,并且多以转录因子和信号通路为研究对象。相比之下,肝脏在个体出生后直至成熟的过程中,虽然肝脏的发育并未停止,但是研究资料相对匮乏。 | Gaofeng Li Tong Ji Jiang Chen Yufei Fu Lidan Hou Yan Feng Tingyue Zhang Tianyu Song Jie Zhao Yoko Endo Hui Lin 蔡秀军 仓勇 | 2018 | 科学新闻2018，0，4： | 0 |
| 11 | Redesign of a short-chain dehydrogenase/reductase for asymmetric synthesis of ethyl (R)-2-hydroxy-4-phenylbutanoate based on per-residue free energy decomposition and sequence conservatism analysis显示文摘As an important building block for the synthesis of angiotensin-converting enzyme inhibitors,ethyl(R)-2-hy-droxyl-4-phenylbutanoate[(R)-HPBE]has attracted increasing attention.The key to industrial biosynthesis of(R)-HPBE is a biocatalyst that efficiently reduces ethyl 2-oxo-4-phenylbutanoate(OPBE)with high R-enantiose-lectivity.This paper proposed a strategy for identifying key residues involved in enantioselectivity control based on per-residue free energy decomposition and sequence conservatism analysis.Using this strategy,4 noncon-servative sites with high energy contribution to binding of OPBE were chosen as engineering targets,generating variant Mu27 with 99%conversion and 98%(R)ee value at substrate loading of up to 500 mmol/L.MD simu-lations suggested the higher stability and formation probability of Mu27-OPBEproR prereaction state as key rea-sons for the excellent R-enantioselectivity of Mu27 towards OPBE.The success in this study provides a viable approach for rational design of alcohol dehydrogenases with high enantioselectivity towards unnatural substrates. | Bingmei Su Lian Xu Xinqi Xu Lichao Wang Aipeng Li Juan Lin Lidan Ye Hongwei Yu | 2020 | Green Synthesis and Catalysis2020，1，2： | 0 |
| 12 | Whether and When Superhydrophobic/Superoleophobic Surfaces Are Fingerprint Repellent显示文摘Driven by the ever-increasing demand for fingerprint-resistant techniques in modern society,numerous researches have proposed to develop innovative antifingerprint coatings based on superhydrophobic/superoleophobic surface design.However,whether superhydrophobic/superoleophobic surfaces have favorable repellency to the microscopic fingerprint is in fact an open question.Here,we establish a reliable method that enables evaluating the antifingerprint capability of various surfaces in a quantitative way.We show that superhydrophobicity is irrelevant with fingerprint repellency.Regarding superoleophobic surfaces,two distinct wetting states of microscopic fingerprint residues,i.e.,the'repellent'and the“collapsed”states,are revealed.Only in the'repellent'state,in which the fingerprint residues remain atop surface textures upon being pressed,superoleophobic surfaces can bring about favorable antifingerprint repellency,which correlates positively with their receding contact angles.A finger-deformation-dependent intrusion mechanism is proposed to account for the formation of diferent fingerprint wetting states.Our findings offer important insights into the mechanism of fingerprint repellency and will help the design of high-performance antifingerprint surfaces for diverse applications. | Chengjiao Wu Yue Fan Hongxin Wang Juan Li Yuxi Chen Yingke Wang Lin Liu Lidan Zhou Shilin Huang Xuelin Tian | 2023 | Research2023，，1： | 0 |
| 13 | Metasurface-enabled polarization-independent LCoS spatial light modulator for 4K resolution and beyond显示文摘With the distinct advantages of high resolution,small pixel size,and multi-level pure phase modulation,liquid crystal on silicon(LCoS)devices afford precise and reconfigurable spatial light modulation that enables versatile applications ranging from micro-displays to optical communications.However,LCoS devices suffer from a long-standing problem of polarization-dependent response in that they only perform phase modulation on one linear polarization of light,and polarization-independent phase modulation-essential for most applications-have had to use complicated polarization-diversity optics.We propose and demonstrate,for the first time,an LCos device that directly achieves high-performance polarization-independent phase modulation at telecommunication wavelengths with 4K resolution and beyond by embedding a polarization-rotating metasurface between the LCoS backplane and the liquid crystal phase-modulating layer.We verify the device with a number of typical polarization-independent application functions including beam steering,holographical display,and in a key optical switching element-wavelength selective switch(WsS),demonstrating the significant benefits in terms of both configuration simplification and performance improvement. | Zhaoxiang Zhu Yuanhui Wen Jiagi Li Yujie Chen Zenghui Peng Jianxiong Liz Lei Zhu Yunfei Wu Lidan Zhou Lin Liu Liangjia Zong Siyuan Yu | 2023 | Light(Science & Applications)2023，12，7： | 0 |
| 14 | Innovative discontinuous-SEI constructed in ether-based electrolyte to maximize the capacity of hard carbon anode显示文摘Compared with graphite,the lower sodiation potential and larger discharge capacity of hard carbon(HC)makes it the most promising anode material for sodium-ion battery.Utilizing ether-based electrolyte rather than conventional carbonate-based electrolyte,HC achieves superior electrochemical performance.Nevertheless,the mechanism by which ether-based electrolyte improves the properties of HC is still controversial,primarily focusing on whether it forms solid electrolyte interphase(SEI)film.In this work,according to the sodium storage mechanisms in HC at low voltage(<0.1 V),including Na^(+)-diglyme co-interaction into the carbon layer(SEI forbidden)and desolvated Na^(+)insertion in the irregular carbon holes(SEI required),the NaPF6concentration in ether-based electrolyte was regulated,so as to construct a discontinuous-SEI on the surface of the HC anode,which significantly enhances the electrochemical performances of HC.Specifically,with 0.2 M NaPF6ether-based electrolyte,HC deliverers a discharge capacity of 459.7 mA h g^(-1)at 0.1 C and stays at 357.2 mA h g^(-1)after 500 cycles at 1 C,which is substantially higher than that of higher/lower salt concentration electrolytes. | Fanghong Zeng Lidan Xing Wenguang Zhang Zhangyating Xie Mingzhu Liu Xiaoyan Lin Guangxia Tang Changyong Mo Weishan Li | 2023 | Journal of Energy Chemistry2023，，4： | 0 |
| 15 | Wrinkling modes of graphene oxide assembled on curved surfaces显示文摘Assembling two-dimensional(2D)sheets into macroscopic three-dimensional(3D)forms has created a promising material family with rich functionalities.Multiscale wrinkles are intrinsic features of 2D sheets in their 3D assembles.Therefore,the precise wrinkling modulation optimizes the transition of outstanding properties of 2D sheets to expected performances of assembled materials and dominates their fabrication process.The wrinkling evolution of 2D sheets assembling onto flat surfaces has been extensively understood,however,the wrinkling behaviors on the more generally curved surface still remain unclear.Here,we investigate the wrinkling behaviors of graphene oxide sheets assembled onto curved surfaces and reveal the selection rule of wrinkling modes that determined by the curvature mismatch between 2D sheets and target surfaces.We uncover that three wrinkling modes including isotropic cracked land,labyrinth,and anisotropic curtain phases,respectively emerge on flat,spherical,and cylindrical surfaces.A favorable description paradigm is offered to quantitatively measure the complex wrinkling patterns and assess the curvature mismatch constraint underlying the wrinkling mode selection.This research provides a general and quantitative description framework of wrinkling modulation of 2D materials such as high performance graphene fibers,and guides the precise fabrication of particles and functional coatings. | Kaiwen Li Zhanpo Han Lidan Wang Jiaqing Wang Chuanwei Zhang Jiahao Lin Shiyu Luo Li Peng Wenzhang Fang Yingjun Liu Ziliang Wu Yeqiang Tan Chao Gao Zhen Xu | 2023 | Nano Research2023，16，2： | 0 |
| 16 | Cysteine mutations impair the structural stability of phosphomannomutase 2(PMM2)in glycosylation-associated metabolic disorders显示文摘Glycosylation is a ubiquitous molecular modification in the process of cellular metabolism regulation,which plays a vital role in maintaining and regulating cellular functions.Deficiency in glycosylation enzymes may jeopardize the glycosylation process and eventually lead to the metabolic disease,manifesting with either a neurologic or multisystem phenotype,which is also known as congenital disorder of glycosylation(CDG).1 It could be classified into type I CDG and type II CDG,and the latter was referred to as the abnormal formation of nascent glycoprotein.Phosphomannomutase 2 CDG(PMM2-CDG),the most prevalent CDG with an incidence rate of 1 in 20,000 individuals,is mainly due to the metabolic disorder of phosphomannomutase 2(PMM2).2 PMM2 participates in the conversion of mannose-6-phosphate to mannose-1-phosphate.The cysteine residues,as one of the least abundant amino acids,have unique attributes to maintain the stability of protein structure,especially for catalytic activity and protein folding.3 Therefore,cysteine mutations have been identified in various diseases including PMM2-CDG.Suggested by the crystal structure of PMM2(PDB ID:7O5Z),4 four cysteine mutations in the hPMM2,C9Y,C103F,C192G,and C241S,have been found in PMM2-CDG.After bioinformatic analysis by PROVEAN,the four cysteine mutations were predicted with“Deleterious”,ranking with the best two were C103F and C192G(C9Y:−5.493,C103F:−6.339,C192G:−11.176,C241S:−2.986).However,the underlying pathological mechanism is still unclear.Among them,C103F and C192G have only been reported in clinical study without a detailed explanation,so they were selected for our research.Two mutants were located near the linker region 1 and 2;C103F was located on the No.4αhelix and C192G was located on the No.7αhelix(Fig.S1A).The purpose of this study was to explore the structure and function roles of PMM2 clinical mutation and investigate the role of cysteine in PMM2 which might provide new insights into preventive and therapeutic strategies for PMM2-CDG. | Yunfan Pan Li Lin Fan Yu Jingmiao Sun Guannan Bai Xinyu He Jianhua Mao Lidan Hu | 2023 | Genes & Diseases2023，10，5： | 0 |
| 17 | E93 promotes transcription of RHG genes to initiate apoptosis during Drosophila salivary gland metamorphosis显示文摘20-hydroxyecdysone(20E)induced transcription factor E93 is important for larval–adult transition,which functions in programmed cell death of larval obsolete tissues,and the formation of adult new tissues.However,the apoptosis-related genes directly regulated by E93 are still ambiguous.In this study,an E93 mutation fly strain was obtained by clustered regularly interspaced palindromic repeats(CRISPR)/CRISPR-associated protein 9-mediated long exon deletion to investigate whether and how E93 induces apoptosis during larval tissues metamorphosis.The transcriptional profile of E93 was consistent with 3 RHG(rpr,hid,and grim)genes and the effector caspase gene drice,and all their expressions peaked at the initiation of apoptosis during the degradation of salivary glands.The transcription expression of 3 RHG genes decreased and apoptosis was blocked in E93 mutation salivary gland during metamorphosis.In contrast,E93 overexpression promoted the transcription of 3 RHG genes,and induced advanced apoptosis in the salivary gland.Moreover,E93 not only enhance the promoter activities of the 3 RHG genes in Drosophila Kc cells in vitro,but also in the salivary gland in vivo.Our results demonstrated that 20E induced E93 promotes the transcription of RHG genes to trigger apoptosis during obsolete tissues degradation at metamorphosis in Drosophila. | Jiahui Zhang Wenhao Zhang Lin Wei Lidan Zhang Jiali Liu Shumin Huang Sheng Li Weike Yang Kang Li | 2023 | Insect Science2023，30，3： | 0 |
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