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| 1 | The Responsivity of the Bacteriorhodopsin Langmuir-Blodgett Film Intermittent Light显示文摘TheResponsivityoftheBacteriorhodopsinLangmuir-BlodgettFilmIntermittentLight￥GuangYuWANG;JianHuaYANG;ZhiGuangZHANG;ShuHuangLIN... | Wang, GY Yang, JH Zhang, ZG Lin, SH Lu, T Li, BF Jiang, L | 1996 | Chinese Chemical Letters1996，7，12： | 12 |
| 2 | The experimental study of genetic engineering human neural stem cells mediated by lentivirus to express multigene显示文摘 | Cai PQ Tang X Lin YQ Martin O Sun GY Xu L Yang YK Zhou TH | 2006 | 中国生物学文摘2006，20，5： | 6 |
| 3 | A prospective, randomized trial of endoscopic hemoclip versus heater probe thermocoagulation for peptic ulcer bleeding显示文摘 | Lin H J Hsieh YH Tseng GY | 2002 | Am J Gastroenterol2002，97，9： | 2 |
| 4 | Effect of hirulog-like peptide on middle cerebral artery occlusion- induced brain injury in mice显示文摘 | Wang RY Lin XJ Yang GY | 2014 | Neuroscience2014，24，277： | 1 |
| 5 | Prone and direct pos- terior approach for management of posterior column tibia1 plateau fractures显示文摘 | Lin KC Tarng YW Lin GY | 2015 | Orthopaedics & Traumatology:Surgery & Research2015，101，4： | 1 |
| 6 | Absence of a genetic relationship between salt tolerance suring seed geminateon and vegetative growth in tomato 显示文摘 | Foolad M R Lin GY | 1997 | Plant Breeding1997，116，： | 1 |
| 7 | A muhicenter study of the as- sociation of serum uric acid, serum creatinine, and diuretic use in hypertensive patients 显示文摘 | Lin CS Hung YJ Chen GY | 2011 | Int J C ardiol2011，148，3： | 1 |
| 8 | Comparative assessment of published atrial fi- brillation stroke risk stratification schemes for predicting stroke, in a non-atrial fibrillation population: The Chin-Shah Community Cohort Study显示文摘 | Lip GY Lin HJ Chien KL | 2013 | Int J Cardi- ol2013，168，1： | 1 |
| 9 | Effects of Ougan juice on P450 activities using a cocktail method 显示文摘 | LIN GY MA JS XU RA | 2012 | Pharmazie2012，67，3： | 1 |
| 10 | Multiple sclerosis presenting initially with a worsening of migraine symptoms显示文摘 | Lin GY Wang CW Chiang Tr | 2013 | J Headache Pain2013，14，： | 1 |
| 11 | The interactions of epigallo-catechin-3-gallate with human whole saliva and parotid saliva显示文摘 | Yao JW Lin CJ Chen GY | 2010 | Arch Oral Biol2010，55，7： | 1 |
| 12 | A 3 - year prospective study of the epidemiology of acute respiratory viral infections in hospitalized chil- dren in Shenzhen, China显示文摘 | He Y Lin GY Wang Q | 2014 | Influenza Other Respir Vir2014，8，4： | 1 |
| 13 | Nonoperative management for extensive hepatic and splenicinjuries with significant hemoperitoneum inadults显示文摘 | Goan GY Huang MS Lin JM | 1998 | J Trauma1998，45，： | 1 |
| 14 | WU polyomavirus infection among children in South China 显示文摘 | Zhuang WL Lu XD Lin GY | 2011 | J Med Viro12011，83，8： | 1 |
| 15 | Dynamic changes in O-GlcNAcylation regulate osteoclast differentiation and bone loss via nucleoporin 153显示文摘Bone mass is maintained by the balance between osteoclast-induced bone resorption and osteoblast-triggered bone formation.In inflammatory arthritis such as rheumatoid arthritis(RA),however,increased osteoclast differentiation and activity skew this balance resulting in progressive bone loss.O-GlcNAcylation is a posttranslational modification with attachment of a single O-linkedβ-D-N-acetylglucosamine(O-GlcNAc)residue to serine or threonine residues of target proteins.Although O-GlcNAcylation is one of the most common protein modifications,its role in bone homeostasis has not been systematically investigated.We demonstrate that dynamic changes in O-GlcNAcylation are required for osteoclastogenesis.Increased O-GlcNAcylation promotes osteoclast differentiation during the early stages,whereas its downregulation is required for osteoclast maturation.At the molecular level,O-GlcNAcylation affects several pathways including oxidative phosphorylation and cell-cell fusion.TNFαfosters the dynamic regulation of O-GlcNAcylation to promote osteoclastogenesis in inflammatory arthritis.Targeted pharmaceutical or genetic inhibition of O-GlcNAc transferase(OGT)or O-GlcNAcase(OGA)arrests osteoclast differentiation during early stages of differentiation and during later maturation,respectively,and ameliorates bone loss in experimental arthritis.Knockdown of NUP153,an O-GlcNAcylation target,has similar effects as OGT inhibition and inhibits osteoclastogenesis.These findings highlight an important role of O-GlcNAcylation in osteoclastogenesis and may offer the potential to therapeutically interfere with pathologic bone resorption. | Yi-Nan Li Chih-Wei Chen Thuong Trinh-Minh Honglin Zhu Alexandru-Emil Matei Andrea-Hermina Györfi Frederic Kuwert Philipp Hubel Xiao Ding Cuong Tran Manh Xiaohan Xu Christoph Liebel Vladyslav Fedorchenko Ruifang Liang Kaiyue Huang Jens Pfannstiel Min-Chuan Huang Neng-Yu Lin Andreas Ramming Georg Schett Jörg H.W.Distler | 2022 | Bone Research2022，10，4： | 1 |
| 16 | A seroepidemiologic study of Chlamydia pneumoniae, Chlamydia trachomatis and Chlamydia psittaci in different populations on the mainland of China显示文摘 | Ni AP Lin GY Yang L | 1996 | Scand J Infect Dis1996，28，6： | 1 |
| 17 | Disseminated angiolymphoid hyperplasia with eosinophilia:a case report显示文摘 | Zhang GY Jiang J Lin T at al | 2003 | Cutis2003，72，： | 1 |
| 18 | Regulation of embryo implantation by nitric oxide in mouse显示文摘Intrauterine injection and zymography were used to investigate the effect of nitric oxide (NO) on embryo implantation in mice. On day 3, one uterine horn of female pregnant mice was injected intraluminally with various doses of nitric oxide synthase (NOS) inhibitor, N-nitro-L-arginine methyl ester (L-NAME), while the contralateral horn served as control. Animals were sacrificed by cervical dislocation on day 7 of gestation, and the number of implanted embryos in each horn was calculated. The results showed that lower doses (0.05mg L-NAME) did not inhibit implantation significantly (P > 0.05), but high doses (0.2 mg L- NAME) resulted in a significant reduction in the number of implanted embryos (P < 0.05). Co-administration of SNP, a generator of NO, with L-NAME would reverse the anti-implantation effect of L-NAME. To further understand the precise mechanism of NO in implantation, matrix metallo-proteinase (MMPs) activities were detected by gelatin zymography. The reduction in the number of implanted | Zhang, X Wang, HM Lin, HY Li, QL Liu, DL Qian, D Liu, GY Zhu, C | 2002 | Chinese Science Bulletin2002，47，17： | 1 |
| 19 | Prone and direct posterior approach for management of posterior column tibial plateau fractures显示文摘 | Lin KC Tarng YW Lin GY | 2015 | Orthop Traumatol Surg Res2015，101，4： | 1 |
| 20 | Association between maternal exlx~ure to elevated ambient sulfer dioxide during pregnancy and term low birth weight 显示文摘 | Lin CM Li CY Yang GY | 2004 | Environ Res2004，96，1： | 1 |
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