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| 1 | Effects of rare earth La on the microstructure and melting property of(Ag-Cu_(28))-30Sn alloys prepared by mechanical alloying显示文摘To obtain novel intermediate temperature alloy solders with a melting temperature of 400-600°C,nominal(Ag-Cu28)-30Sn alloys without or with a trace addition(0.5 or 1.0 wt.%) of rare earth(RE) element La were prepared by mechanical alloying.The aim of this research is to investigate the effects of the addition of La on the microstructures,alloying process and melting properties of(Ag-Cu28)-30Sn alloys.The results show that the addition of La produces no new phase.A trace amount of La addition can effectively refine the grain size,but the excessive addition of 1.0 wt.% La inhibits the alloying process.The influence of La on the melting temperatures of solder alloys is negligible.However,the trace addition of 0.5 wt.% La can distinctly reduce the fusion zone and improve the melting property of(Ag-Cu28)-30Sn alloys. | LI Liangfeng QIU Tai YANG Jian FENG Yongbao | 2011 | Rare Metals2011，30，1： | 6 |
| 2 | NUMERICAL SIMULATION OF WET STEAM CONDENSING FLOW WITH AN EULERIAN/EULERIAN MODEL显示文摘Wet steam condensing flow in low-pressure steam turbine leads to efficiency losses and blade erosions.In order to investigate this problem by numerical approach, an Eulerian/Eulerian model has been developed, in which the wet steam is regarded as mixture comprising two coupled systems: the vapor phase and the liquid phase.These two systems are both described by conservation equations.High resolution TVD scheme is employed to capture condensing phenomena in wet steam flow.This model has been validated by numerical simulations of condensing flows in 1D and 2D nozzles.Compared with experimental data, a good agreement is observed.This Eulerian/Eulerian model can be extended to 3D calculation of condensing flow. | Li LiangFeng ZhenpingLi GuojunState Key Laboratory of Multiphase Flowin Power Engineering,Xi’ an Jiaotong University,XI’ an 710049, China | 2003 | Chinese Journal of Mechanical Engineering2003，16，2： | 3 |
| 3 | Corynoxine B targets at HMGB1/2 to enhance autophagy forα-synuclein clearance in fly and rodent models of Parkinson's disease显示文摘Parkinson's disease(PD)is the most common neurodegenerative movement disease.It is featured by abnormal alphα-synuclein(α-syn)aggregation in dopaminergic neurons in the substantia nigra.Macroautophagy(autophagy)is an evolutionarily conserved cellular process for degradation of cellular contents,including protein aggregates,to maintain cellular homeostasis.Corynoxine B(Cory B),a natural alkaloid isolated from Uncaria rhynchophylla(Miq.)Jacks.,has been reported to promote the clearance ofα-syn in cell models by inducing autophagy.However,the molecular mechanism by which Cory B induces autophagy is not known,and theα-syn-lowering activity of Cory B has not been verified in animal models.Here,we report that Cory B enhanced the activity of Beclin 1/VPS34 complex and increased autophagy by promoting the interaction between Beclin 1 and HMGB1/2.Depletion of HMGB1/2 impaired Cory B-induced autophagy.We showed for the first time that,similar to HMGB1,HMGB2 is also required for autophagy and depletion of HMGB2 decreased autophagy levels and phosphatidylinositol 3-kinaseⅢactivity both under basal and stimulated conditions.By applying cellular thermal shift assay,surface plasmon resonance,and molecular docking,we confirmed that Cory B directly binds to HMGB1/2 near the C106 site.Furthermore,in vivo studies with a wild-typeα-syn transgenic drosophila model of PD and an A53Tα-syn transgenic mouse model of PD,Cory B enhanced autophagy,promotedα-syn clearance and improved behavioral abnormalities.Taken together,the results of this study reveal that Cory B enhances phosphatidylinositol 3-kinaseⅢactivity/autophagy by binding to HMGB1/2 and that this enhancement is neuroprotective against PD. | Qi Zhu Juxian Song Jia-Yue Chen Zhenwei Yuan Liangfeng Liu Li-Ming Xie Qiwen Liao Richard D.Ye Xiu Chen Yepiao Yan Jieqiong Tan Chris Soon Heng Tan Min Li Jia-Hong Lu | 2023 | Acta Pharmaceutica Sinica B2023，13，6： | 2 |
| 4 | SolidEarth: a new Digital Earth system for the modeling and visualization of the whole Earth space显示文摘尽管许多归化为美国人的数字地球系统证明了为建模和与地球表面相关、近表面的 geospatial 对象的可视化相当有用,他们没为在地质或大气的空格当模特儿和应用程序的目的被设计。对能与完整的维数处理 geospatial 信息的一个新数字地球系统有紧迫的需要。在这份报纸,我们在场一个新数字地球系统,称为的 SolidEarth 作为为包括它的表面当模特儿和整个地球空间的可视化的一个其他的虚拟地球,内部、外面的空间。SolidEarth 由四个功能的部件组成:在地理空间当模特儿,在地质的空间当模特儿,在大气的空间当模特儿,并且,综合可视化和分析。SolidEarth 有一个全面处理到第三种空间尺寸和一系列复杂 3D 空间分析功能。因此,它对容量的表示和 inner/ 的视觉分析很相配在地球空间的外部范围。SolidEarth 能在象地球科学研究那样的很多个领域里被使用,教育,数字地球应用程序的构造,和另外的专业版土练习科学。 | Liangfeng ZHU Jianzhong SUN Changling LI Bing ZHANG | 2014 | Frontiers of Earth Science2014，8，4： | 1 |
| 5 | Build-ing 3D solid models of sedimentary stratigraphic systems fromborehole data: An automatic method and case studies显示文摘 | Zhu Liangfeng Zhang Chengjuan Li Mingjiang | 2012 | En-gineering Geology >2012，127，1： | 1 |
| 6 | Research on Systematic Analysis and Countermeasures of the Buildings Construction Safety Problems显示文摘The buildings construction safety problems contain various safety-hidden dangers that caused by the human unsafe behaviors,the substance unsafe conditions,operation environment unsafe factors and management defects.The authors summarize comprehensively the problems of buildings construction safety in China at present based on grasping the whole safety status of buildings construction,and the synthetic countermeasures including the systems about laws,management,technology and education civilization for buildings construction safety management are brought up based on the viewpoint of safety system theory.Then it is thought that building scientific management mechanisms and popularizing effective management methods and measures are the fundamental ways for improving further the level of safety management for buildings construction in China at present. | Shen Liangfeng Li Jie Fan Yeming | 2008 | Engineering Sciences2008，6，1： | 1 |
| 7 | Investigation of rotor–stator interaction broadband noise using a RANS-informed analytical method显示文摘A Reynolds-Averaged Navier Stokes(RANS)-information analytical method for predicting Rotor-Stator Interaction(RSI)broadband noise is established in this paper.First,the turbulence information is deduced from RANS simulation result.Then,the unsteady load on the stator blade is calculated using a strip theory approach based on LINearized SUBsonic unsteady flow in cascade(LINSUB)and 2-D equivalence method.In the end,the sound power of RSI broadband noise is calculated by coupling the unsteady load on the stator blade with acoustic analogy and annular duct mode.The broadband noise model part of the RANS-information analytical method is validated against the upstream sound power of an annular cascade experimental bench.Besides,the RANS-information analytical method is used in predicting RSI broadband noise of a single-stage axial fan acoustic experimental bench,the results illustrate that the RANS-information analytical method can accurately predict the RSI broadband noise in different fan working conditions.After simplification the Wave Leading Edge(WLE)stator blade,the effect of WLE stator blade on RSI broadband noise is studies.Although the simplification may bring some discrepancies,the results illustrate that the RANS-information analytical method has the capability for further studies on the broadband noise reduction with WLE stator blade. | Hang TONG Lin LI Liangfeng WANG Luqin MAO Weiyang QIAO | 2021 | Chinese Journal of Aeronautics2021，34，10： | 1 |
| 8 | Assessing impact of irrigation water on groundwater recharge and quality in arid environment using CFCs, tritium and stable isotopes, in the Zhangye Basin, Northwest China显示文摘 | Dajun Qin Yunping Qian Liangfeng Han Zhimin Wang Chen Li Zhanfeng Zhao | 2011 | Journal of Hydrology2011，，1： | 1 |
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