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| 1 | Association of farnesyl diphosphate synthase polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis显示文摘 | Liu Y Li M Zhou PR Xing XP Xia WB Xu L Liu H J Zhang ZL LiaoEY Chen DC Liu J Tao TZ Wu W | 2014 | Chinese Medical Journal2014，，4： | 16 |
| 2 | Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels显示文摘 | Fu H Li W Lao Y Luo J Lee NT Kan KK Tsang HW Tsim KW Pang Y Li Z Chang DC Li M Han Y | 2006 | 中国生物学文摘2006，20，10： | 10 |
| 3 | Protective effect of early enteral feeding on postburn impairment of liver function and its mechanism in rats显示文摘AIM To study the protective effect of earlyenteral feeding(EEF)on the postburnimpairment of liver function and its mechanism.METHODS Wistar rats with 30% of total bodysurface area(TBSA)full-thickness burn wereemployed.The effects of EEF on the postburnchanges of gastric intramucosal pH,endotoxinlevels in portal vein,water contents of hepatictissue,blood concentrations of tumor necrosisfactor(TNF-α),plasma activities of alanineaminotransferase(ALT)and asparateaminotransferase(AST),as well as the bloodcontents of total(TB)and direct bilirubin(DB),total protein(TP)and albumin(ALB)wereserially determined within 48h postburn.RESULTS EEF could significantly improvegastric mucosal acidosis,reduce portal veinendotoxin level and water content of hepatictissue,as well as plasma concentrations of TNF-α at all timepoints after severe burns(P<0.01);postburn elevation of the plasma activities ofALT,AST and the contents of TB,DB wereeffectively prevented,whereas the plasmaconcentrations of TP and ALB were markedlyincreased 24 h and 48 h posturn in EEF groupcompared with that of the burn without EEFgroup(P<0.01).CONCLUSION EEF has significant beneficialeffects on the improvement of hepatic function in rats after severe burn,and is probably relatedwith an increase in splanchnic blood flow,reduction of the absorption of gut-originendotoxin and the consequent release ofinflammatory mediators. | Zhu L Yang ZC Li A Cheng DC | 2000 | World Journal of Gastroenterology2000，6，1： | 10 |
| 4 | Reduced gastric acid production in burn shock period and its significance in the prevention and treatment of acute gastric mucosal lesions显示文摘AIM To investigate the changes of gastric acidproduction and its mechanism in shock period ofsevere burn in rats.METHODS A rat model with 30% TBSA full-thickness burn injury was employed and thegastric acid production,together with gastricmucosal blood flow(GMBF)and energy charge(EC)were measured serially within 48hpostburn.RESULTS The gastric acid production in theacute shock period was markedly inhibited aftersevere burn injury.At the 3rd h postburn,thegastric juice volume,total acidity and acidoutput were already significantly decreased(P<0.01),and reached the lowest point,0.63mL/L±0.20mL/L,10.81mmol/L±2.58mmol/L and 2.23mmol/h±0.73mmol/hrespectively,at the 12th h postburn.Althoughrestored to some degree 24 h after thermalinjury,the variables above were stillstatistically lower,compared with those ofcontrol animals at the 48th h postburn.TheGMBF and EC were also significantly reducedafter severe burns,consistent with the trend ofgastric acid production changes.CONCLUSION Gastric acid production,as wellas GMBF and EC was predominantly decreased in the early postburn stage,suggesting that gastricmucosal ischemia and hypoxia with resultantdisturbance in energy metabolism,but notgastric acid proper,might be the decisive factorin the pathogenesis of AGML after thermalinjury,and that the preventive use of anti-aciddrugs during burn shock period wasunreasonable in some respects.Therefore,taking effective measures to improve gastricmucosal blood perfusion as early as possiblepostburn might be more preferable for the AGMLprevention and treatment. | Zhu L Yang ZC Li A Cheng DC | 2000 | World Journal of Gastroenterology2000，6，1： | 7 |
| 5 | Attitudes of Ch-inesemedical students towardthe IIME GlobalMinimum Essential Require-ments显示文摘 | Zhang X Li X Wan X Zeng C Scott CS Schaad DC | 2004 | Teaching and Learning in Medicine2004，16，2： | 1 |
| 6 | Evolution of soil chemical properties in the past 50 years in the Tai Lake Region, China显示文摘 | Wang H Dong YH Li DC Velde B An Q Guo ZX Zuo QD | 2008 | Soil and Tillage Research2008，100，12： | 1 |
| 7 | Attenuation of osteoarthritis via blockade of the SDF - 1/CXCR4 signaling pathway显示文摘 | Wei F Moore DC Li Y | 2012 | Arthritis Res Ther2012，14，： | 1 |
| 8 | Pharmacokinetic/pharmacodynamic model for corticosteroid receptor /gene-mediated mechanism显示文摘 | Sun YN McKay LI Dubois DC | 1999 | J Pharmacol Exp Ther1999，288，： | 1 |
| 9 | Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph nodenega- tire breast carci-noma 显示文摘 | Li HC Can DC Liu Y | 2004 | Breast Cancer Res Treat2004，88，1： | 1 |
| 10 | Clay minerals in a soil chronosequence derived from basalt on Hainan Island, China and its implication for pedogenesis显示文摘 | He Y Li DC Velde B Yang YF Huang CM Gong ZT Zhang GL | 2008 | Geoderma2008，148，： | 1 |
| 11 | Inhibitory effect of medroxyprogesterone acetate on human liver cytochrome P450 enzymes显示文摘 | Zhang JW Liu Y Li W Hao DC Yang L | 2006 | Eur J Clin Pharmacol2006，62，7： | 1 |
| 12 | A new mapping rule for RNA secondary structures with its applications显示文摘 | BAI FL LI DC WANG TM | | 0，，： | 1 |
| 13 | Prognostic value of matrix metalloproteinases(MMP2 and MMP9)in patients with lymph node-negative breast car-cinoma显示文摘 | Li HC Cao DC Liu Y | | 0，，： | 1 |
| 14 | The cancer antiapoptosis mouse survivin gene: characterization of locus and transcriptional requirements of basal and cecycle-dependent expression 显示文摘 | Li F Altieri DC | 1999 | Cancer Res1999，59，13： | 1 |
| 15 | Death receptor 6 induces apoptosis not through type I or type II pathways, but via a unique mitochondria- dependent pathway by interacting with Bax protein显示文摘 | Zeng L Li T Xu DC | 2012 | J Biol Chem2012，287，29： | 1 |
| 16 | One-pot production of hydrocarbons from xylitol by hydroiodic acid reduction显示文摘 | Lv DC Liu YQ Li SR | 2015 | Fuel Processing Technology2015，，131： | 1 |
| 17 | FIZZ1/REL Malpha,novel hypoxia-induced mitogenic factor in lung with vasoconstrictive and angiogenic properties显示文摘 | Li DC Champion HC | 2003 | Circulation Research2003，92，： | 1 |
| 18 | Effects of gastric pacing on gastric emptying and plasma motilin显示文摘 | Yang M Fang DC Li QW | 2004 | World J Gastroenterol2004，10，3： | 1 |
| 19 | Transcriptional analysis of human survivin gene expression显示文摘 | Li F Altieri DC | 1999 | Biochem J1999，344，2： | 1 |
| 20 | Transcriptional analysis of human survivin gene expression显示文摘 | Li F Altieri DC | 1999 | Biochem J1999，344，： | 1 |
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