|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A long-term follow-up study on hepatitis B surface antigen-positive patients undergoing allogeneic hematopoietic stem cell transplantation显示文摘 | Hui CK Lie A Au WY Leung YH Ma SY Cheung WW Zhang HY Chim CS Kwong YL Liang R Lau GK | 2006 | 中国生物学文摘2006，20，5： | 10 |
| 2 | 成人型梭行细胞横纹肌肉瘤高频发生MYOD1基因反式激活突变显示文摘习惯上将横纹肌肉瘤(RMS)分为以下3型,即腺泡状横纹肌肉瘤(ARMS)、胚胎型横纹肌肉瘤(ERMS)及多形性横纹肌肉瘤(PRMS),而ERMS中包括了梭形细胞RMS。在2013版的WHO软组织及骨肿瘤分类中,梭形细胞RMS已从ERMS中分离出来,其梭形细胞/硬化性RMS被列为一种独立的类型。迄今为止,成人梭形细胞RMS并未被检测到高频发生的基因突变。 | Szuhai K de Jong D Leung A Y 杨文婷(摘译) 余英豪(审校) | 2014 | 临床与实验病理学杂志2014，30，5： | 6 |
| 3 | Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring显示文摘现在有充分证据,对在使肥沃的后代显型的父亲的贡献多于公平 DNA。然而,这 nongenetic 继承的身份和机制糟糕被理解。在这个研究区域的更重要的问题之一是:在精子 DNA methylation 的变化为后代有 phenotypic 后果吗?我们以前报导了肥胖的雄的老鼠的后代与控制相比改变了葡萄糖新陈代谢并且这效果通过 nongenetic 工具被继承。这里,我们用一样的协议在一个新队描述调查进精子 DNA methylation。在高脂肪的节食的雄的老鼠是 30% 比喂控制的男性重在交配的时候(16-19 星期旧, n = 14/14 ) 。一小(0.25%) 在全部的 5-methyl-2 ’ 增加; -deoxycytidine 被液体层析双人脚踏车团 spectrometry 在肥胖的老鼠精子检测。那 retrotransposon DNA methylation 在精子说的有定序的充实蛋白质的染色体(MBD-Seq ) 和 pyrosequencing 揭示了的 methyl-CpG 绑定领域的染色体的重复部分的检查没被肥胖,而是 methylation 在整个染色体在卫星重复影响被增加。然而,从男 27-week-old 后代从的肌肉,肝,和精子的检查肥胖并且控制父亲(从 8 生的 n = 的两个组) 表明正常 DNA methylation 层次在后代开发期间被恢复。而且,没有变化在肥胖的老鼠精子在三个 genomic 印记被发现。我们的调查结果为 transgenerational epigenetic reprogramming 有含意。他们建议 postfertilization 机制为使导致 environmentally 的 DNA methylation 在精子房间改变的一些正常化存在。 | Neil A Youngson Virginie Lecomte Christopher A Maloney Preston Leung Jia Liu Luke B Hesson Fabio Luciani Lutz Krause Margaret J Morris | 2016 | Asian Journal of Andrology2016，18，6： | 3 |
| 4 | Sedated vs unsedated colonoscopy:A prospective study显示文摘AIM:To compare sedated to unsedated colonoscopy in terms of duration,pain and the patient’s willingness to repeat the procedure.METHODS:Consecutive patients who underwent colonoscopies over a 2-year period were invited to participate.All patients who were to undergo our endoscopy unit were offered sedation with standard intravenous sedatives and analgesics,or an unsedated colonoscopy was attempted.Demographic details were recorded.The patient anxiety level prior to the procedure,time to reach the cecum,total discharge time,patient and endoscopist pain assessments,satisfaction after the examination and the patient’s willingness to return for the same procedure in the future were recorded.RESULTS:Among the 403 observed patients,more males were observed in the unsedated group(66.2%vs 55.2%,P=0.04).Additionally,the unsedated group patients were less anxious prior to the procedure(5.1vs 6.0,P<0.01).The colonoscopy completion rates were comparable between the 2 groups(85.9%vs84.2%,P=0.66).The time to reach the cecum was also comparable(12.2 min vs 11.8 min);however,the total discharge times were shorter in the unsedated group(20.7 min vs 83.0 min,P<0.01).Moreover,the average patient pain score(3.4 vs 5.7,P<0.01)was lower in the sedated group,while the satisfaction score(8.8 vs 7.8,P<0.01)was significantly higher.There was no significant difference,however,between the groups in terms of willingness to repeat the procedure if another was required in the future(83.3%vs 77.3%,P=0.17).CONCLUSION:Unsedated colonoscopy is feasible in willing patients.The option saves the endoscopy units up to one hour per patient and does not affect the patient willingness to return to the same physician again for additional colonoscopies if a repeated procedure is needed. | Abdulrahman M Aljebreen Majid A Almadi Felix W Leung | 2014 | World Journal of Gastroenterology2014，20，17： | 3 |
| 5 | 评估内燃机隔振系统功率流传递的一种新模型(英文)显示文摘为准确评估弹性复杂隔振基础条件下振动内燃机的功率流传递水平,采用Mindlin板替代传统的Kirchihoff薄板,建立了一种涵盖多种隔振基础形式的普适模型。运用子结构技术和变分理论,推导了隔振系统的控制方程以及传递到较厚甚至不同配置方式的各向异性复杂梁式基础的功率流。与基于各向同性薄板基础的传统模型相比较,研究了普适隔振系统功率流的传递特性。仿真研究表明,所提模型是有效的,可得到比传统模型更加准确的结果。 | 牛军川 葛培琪 林志华 梁以德 宋孔杰 LIM C W LEUNG A Y T | 2009 | 内燃机学报2009，27，1： | 3 |
| 6 | 危重患者抗菌药物持续静脉滴注或延长滴注时间:系统综述和meta分析显示文摘危重患者抗菌药物持续静脉滴注或延长滴注时间:系统综述和meta分析
摘译:本研究对入住ICU危重患者使用以药物代谢动力学为基础的方法行抗菌药物持续静脉滴注或延长静脉滴注时间,并与传统间歇性静脉滴注抗菌药物进行比较,观察包括病死率在内的各种预后变化。 | 罗勇 Chant C Leung A Frienrich J O | 2014 | 临床误诊误治2014，27，8： | 3 |
| 7 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 3 |
| 8 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 2 |
| 9 | Solution procedure of residue harmonic balance method and its applications显示文摘This paper presents a simple and rigorous solution procedure of residue harmonic balance for predicting the accurate approximation of certain autonomous ordinary differential systems.In this solution procedure,no small parameter is assumed.The harmonic residue of balance equation is separated in two parts at each step.The first part has the same number of Fourier terms as the present order of approximation and the remaining part is used in the subsequent improvement.The corrections are governed by linear ordinary differential equation so that they can be solved easily by means of harmonic balance method again.Three kinds of different differential equations involving general,fractional and delay ordinary differential systems are given as numerical examples respectively.Highly accurate limited cycle frequency and amplitude are captured.The results match well with the exact solutions or numerical solutions for a wide range of control parameters.Comparison with those available shows that the residue harmonic balance solution procedure is very effective for these autonomous differential systems.Moreover,the present method works not only in predicting the amplitude but also the frequency of bifurcated period solution for delay ordinary differential equation. | GUO ZhongJin LEUNG A Y T MA XiaoYan | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，8： | 2 |
| 10 | Size distributions of maternal and fetal DNA in maternal plasma显示文摘 | Chan K C ZhangJ Hui A B Wong N Lau T K Leung T N | 2004 | Clin Chem2004，50，： | 1 |
| 11 | Structure of the 2 promoters of the human LCK gene differential accumulation of 2 classes of LCK transcripts in T-cells 显示文摘 | Takadera T Leung S Gernone A | 1989 | Mol Cell Biol1989，9，： | 1 |
| 12 | Sex differences in schizophrenia, a review of the literature显示文摘 | Leung A Chue P | 2000 | Acta Psychiatr Scand Suppl2000，，： | 1 |
| 13 | Stochastic spline ritz method based on stochastic variational principle 显示文摘 | Yang L F Leung A Y T Yan L B | 2005 | Engineering Structures2005，27，3： | 1 |
| 14 | Photofluxonic detection: A new mechanism for infrared detection in superconducting thin film显示文摘 | Kadin A M Leung M Smith A D | 1990 | Appl Phys Lett1990，7，26： | 1 |
| 15 | Smoothing Newton method for solving two-and three-dimensional frictional contact problems显示文摘 | Leung A Y T | 1998 | Int J Numer Meth Engng1998，41，： | 1 |
| 16 | A prospective randomized study of chemotherapy adjunctive to definitive radiotherapy in advanced nasopharyngeal carcinoma显示文摘 | Chan A T Teo P M Leung T W | 1995 | Int J Radiat Oncol Biol Phys1995，33，3： | 1 |
| 17 | Effect of supplementation of leukemia inhibitory factor and epidermal growth factor on murine embryonic development in vitro, implantation, and outcome of offspring显示文摘 | Cheung L P Leung H Y Bongso A | 2003 | Fertil Steril2003，80，2： | 1 |
| 18 | Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong显示文摘 | Donnelly C A Ghani A C Leung G M | 2003 | Lancet2003，361，： | 1 |
| 19 | Total laparoscopic hysterectomy versus total abdominal hysterectomy for obese women with endometrial cancer显示文摘 | Obermair A Manolitsas TP Leung Y | 2005 | Int J Gynecol Cancer2005，15，2： | 1 |
| 20 | Strong association of SYT-SSX fusion type and morphologic epithelial differentiation in synovial sarcoma显示文摘 | Antoneseu CR Kawai A Leung DH | 2000 | Diaga Mol Pathol2000，9，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员