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| 1 | Non-alcoholic fatty liver disease and diabetes: From physiopathological interplay to diagnosis and treatment显示文摘Non-alcoholic fatty liver disease(NAFLD)is highly prevalent in patients with diabetes mellitus and increasing evidence suggests that patients with type 2diabetes are at a particularly high risk for developing the progressive forms of NAFLD,non-alcoholic steatohepatitis and associated advanced liver fibrosis.Moreover,diabetes is an independent risk factor for NAFLD progression,and for hepatocellular carcinoma development and liver-related mortality in prospective studies.Notwithstanding,patients with NAFLD have an elevated prevalence of prediabetes.Recent studies have shown that NAFLD presence predicts the development of type2 diabetes.Diabetes and NAFLD have mutual pathogenetic mechanisms and it is possible that genetic and environmental factors interact with metabolic derangements to accelerate NAFLD progression in diabetic patients.The diagnosis of the more advanced stages of NAFLD in diabetic patients shares the same challenges as in non-diabetic patients and it includes imaging and serological methods,although histopathological evaluation is still considered the gold standard diagnostic method.An effective established treatment is not yet available for patients with steatohepatitis and fibrosis and randomized clinical trials including only diabetic patients are lacking.We sought to outline the published data including epidemiology,pathogenesis,diagnosis and treatment of NAFLD in diabetic patients,in order to better understand the interplay between these two prevalent diseases and identify the gaps that still need to be fulfilled in the management of NAFLD in patients with diabetes mellitus. | Nathalie C Leite Cristiane A Villela-Nogueira Claudia R L Cardoso Gil F Salles | 2014 | World Journal of Gastroenterology2014，20，26： | 21 |
| 2 | Theinfluence of Ge-implantation on the electrical characteristics of the ultra-shallow junction formed by using silicide as a diffusion source显示文摘 | HUANGCT LEIT F CHUC H | 1996 | Electron Device Letters1996，17，3： | 1 |
| 3 | Application of chronological load modeling in composite reliability worth evaluation显示文摘 | Mello J C O Pereira M V F Leite da Silva A M | 1997 | Electric Power Systems Research1997，，40： | 1 |
| 4 | Laboratory evaluation of recycled construction and demolition waste for pavements显示文摘 | Leite F D Motta R S Kamilla L V | 2011 | Construction and Building Materials2011，25，6： | 1 |
| 5 | Brown pigment of the nanopowder spinel ferrite prepared by combustion reaction显示文摘 | COSTA A C F M LEITE A M D FERREIRA H S | | 0，，： | 1 |
| 6 | Activation of the PI3K/Akt pathway early during vaccinia and cowpox virus infections is required for both host survival and viral replication 显示文摘 | SOARES J A LEITE F G ANDRADE L G | 2009 | J Virol2009，83，13： | 1 |
| 7 | Antineoplastic activity of selected constituents of Duguetia glabriuscula 显示文摘 | Matos M F Leite L I Brustolim D | 2006 | Fitoterapia2006，77，3： | 1 |
| 8 | Preparation of composite materials Containing iron in a cross-linked resin host based on styrene and divinylbenzene 显示文摘 | De Santa Maria L C Leite M C A M Senna L F | 2003 | European Polymer Journal2003，39，4： | 1 |
| 9 | Complexities of patho- genesis of Mannheimia haemolytica and Haemophilus somnus infections: Challenges and potential opportunities for prevention? 显示文摘 | Czuprynski D J Leite F Sylte M | 2004 | Anim HealthRes Rev2004，5，2： | 1 |
| 10 | Detection of human papillomavirus DNA by the hybrid capture assay显示文摘 | Carvalho M O Almeida R W Leite F M | 2003 | Braz J Infect Dis2003，7，2： | 1 |
| 11 | Detection of field isolates of human and animal group C rotavirus by reverse transcription-polymerase chain reaction and digorigenin-labeled oligonucleotide probes显示文摘 | Alfieri A A Leite J P Alfieri A F | 1999 | J Vriol Methods1999，83，12： | 1 |
| 12 | Evaluation of two guidelines for the management of hyperbilirubinemia in newborn babies weighing less than 2,000 g显示文摘 | Leite M Facchini F | 2004 | Pediatr (Rio J)2004，80，4： | 1 |
| 13 | The effects of skin-toskin contact during acute pain in preterm newborns显示文摘 | CastralTC Warnock F Leite AM etal | 2008 | Eur J Pain2008，12，4： | 1 |
| 14 | Production and characteristics comparison of crude β-glucosidases produced by microorganisms Thermoascus aurantiacus e Aureobasidium pullulans in agricultural wastes显示文摘 | LEITE R S R ALVES-PRADO H F CABRAL H | | 0，，06： | 1 |
| 15 | Crystal growth in colloidal tin oxide nanocrystals induced by coalescence at room temperature显示文摘 | LEITE E R GIRALDI T R PONTERS F M | 2003 | Applied Physical Letter2003，83，8： | 1 |
| 16 | Tracking of clinical and environmental Vibrio cholerae O1 strains by combined analysis of the presence of toxin cassette, plasmid content and ERIC PCR 显示文摘 | Mastrandrea S Leite F | 1997 | FEMS Immunol Med Microbiol1997，19，1： | 1 |
| 17 | Malnutrition as an in- dependent predictor of clinical outcome in critically ill children 显示文摘 | Souza Menezes F Leite HP Koch Nogueira PC | 2012 | Nutri2012，28，3： | 1 |
| 18 | Biosorption of copper by Paenibacillus polymyxa cells and their exopolysaccharide 显示文摘 | ACOSTA M P VALAMAN E LEITE S G F | 2005 | World Jouranal of Microbiology & Biotechnology2005，21，： | 1 |
| 19 | TEM, XRD and AFM study of poly (o-ethoxyaniline) films : new evidence for the formation of conducting islands 显示文摘 | Leite F L Alves WF Mir M | 2008 | Applied Physics A2008，，93： | 1 |
| 20 | Adsorption of chitosan on spin-coated cellulose films显示文摘 | Da Róz A L Leite F L Pereiro L V | 2011 | Carbohyd Polym2011，80，： | 1 |
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