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| 1 | 蚯蚓(Eiseniafetida)细胞色素P450及抗氧化酶系对环境浓度苯并(a)芘的响应显示文摘以赤子爱胜蚓(Eisenia fetida)为供试生物,草甸棕壤为供试土壤,以蚯蚓微粒体细胞色素P450含量、抗氧化酶系以及谷胱甘肽转移酶活性为指标,进行了土壤中苯并(a)芘[B(a)P]暴露与酶活性的量-效关系研究。结果表明,在接近沈抚灌区实地污染状况B(a)P(0.1~2.0mg.kg-1)暴露下,第1、3、7以及第14d取样时,P450和SOD有较好的响应:SOD在第1、3d显著升高,而在第7、14d时降低;P450总体表现为低浓度B(a)P诱导下降低,高浓度下升高的趋势。CAT、POD以及GST的敏感性相对较差。比照其他4个指标,蚯蚓P450的敏感性更为优异,具有较好的应用前景。指标敏感性总体表现为:P450>SOD>CAT/POD>GST。 | 王磊 宋玉芳 张薇 陈朗 David Freestone M Leigh Ackland | 2009 | 农业环境科学学报2009，28，2： | 12 |
| 2 | 植物CytP450和抗氧化酶对土壤菲、芘暴露的生态毒理响应显示文摘以玉米(ZeamaysL.)为供试植物,草甸棕壤为供试土壤,以微粒体细胞色素P450含量、超氧化物歧化酶(SOD)、过氧化氢酶(CAT)和过氧化物酶(POD)活性为指标,进行了土壤菲、芘暴露的生态毒理响应研究.结果表明,菲、芘暴露均能引起植物代谢解毒和抗氧化防御系统的胁迫响应,不同程度引发植物代谢解毒及抗氧化能力的改变.P450酶活性与低浓度菲、芘单一暴露浓度具有相关性(r=0.834,p<0.01),与菲、芘复合暴露浓度负相关,说明菲、芘复合暴露导致代谢解毒能力下降,对植物的代谢解毒具有协同毒性效应;SOD酶活性与菲、芘单一暴露浓度负相关,CAT酶活性与菲、芘单一暴露浓度正相关,POD酶活性与菲的水溶解度正相关,而与芘的总浓度负相关.SOD、CAT和POD酶活性与菲、芘复合暴露浓度均呈正相关,说明菲、芘复合暴露导致氧化损伤程度减弱,对植物的氧化损伤具有拮抗作用. | 宋玉芳 王磊 李昕馨 张薇 陈朗 Freestone David 吉普辉 Ackland M Leigh | 2009 | 环境科学学报2009，29，2： | 9 |
| 3 | A response to 'Dewey and Vygotsky: Society, experience, and inquiry in educational practice' 显示文摘 | O'Brien Leigh M | 2002 | Educational Researcher2002，31，5： | 1 |
| 4 | The influence of artificial macropores on water and solute transport in ]aboratory soil co]urnns 显示文摘 | Buttle J M Leigh D G | 1997 | Journal of Hydrology1997，17，： | 1 |
| 5 | A Holy Grail of asthma management:toward understanding how long-acting beta(2)-adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids显示文摘 | Giembycz MA Kaur M Leigh R | | 0，，： | 1 |
| 6 | Half-rotation in a kinetically lockedcatenane induced by transition metal ion substitution显示文摘 | Leigh D A Lusby P J Slawin A M | 2012 | Chem Commun2012，48，47： | 1 |
| 7 | Certification of SRM 1589a PCBs, pesticides, PBDEs, and dioxins/furans in human serum显示文摘 | Schantz M Keller J Leigh S | 2007 | Anal Bioanal Chem2007，389，4： | 1 |
| 8 | Online Mathematics Achievement: Effects of Learning Strategies and Seff-Etllcacy显示文摘 | Leigh M Wadsworth Jenefer Husman Mary Anne Duggan M Nan Pennington | 2007 | Joumal of Developmental Education2007，，3： | 1 |
| 9 | The image invention dur- ing the competitive season with an elite union player显示文摘 | LYNNE E LEIGH J RICHARD M | 2004 | Sport Psychol2004，，8： | 1 |
| 10 | Environmental indicators of macroinvertebrate and fish assemblage integrity in urbanizing watersheds 显示文摘 | WALTERS D M ROY A H LEIGH D S | 2009 | Ecological Indicators2009，，9： | 1 |
| 11 | A robust method for quantification of volatile compounds within and between vintages using headspace-solid-phase micro-extraction coupled with GC-MS:applica-tion on Semillon wines显示文摘 | REBIERE L CLARK A C LEIGH M S | 2010 | Anal Chim Acta2010，660，： | 1 |
| 12 | Debt, Equity, and Capital Investment 显示文摘 | Scott B Jackson Timothy M Keune Leigh Salzsieder | 2013 | Journal of Ac- counting and Economies2013，56，： | 1 |
| 13 | Advantages of isothermal titration calorimetry for xylanase kinetics in comparison to chemical-reducing-end assays 显示文摘 | MARTIN J B LEIGH M PETER W | 2011 | Analytical Biochemistry2011，，410： | 1 |
| 14 | Cellulose utilization in forest litter and soil: identification of bacterial and fungal decomposers显示文摘 | Stursov~i M if6tkovi L Leigh BM | 2012 | FEMS Microbiology Ecology2012，80，3： | 1 |
| 15 | PTEN in- duced vascular endothelial growth fator secretion in head and neck squamous cell carcinoma显示文摘 | Mark G S Leigh A B Megan M K | 2005 | Biochem Biophys Res Commun2005，331，3： | 1 |
| 16 | Effects of budesonide and formoterol on allergeninduced airway responses inflammation and airway remodeling in asthma显示文摘 | Leigh R Kelly M | 2010 | J Allergy Clin Immunol2010，125，2： | 1 |
| 17 | AnImprovementtotheInteracting MultipleModel(IMM)Algorithm显示文摘 | LEIGH AJOHNSTON VIKRA M K | 2001 | IEEETransactionsonSignalProcessing2001，49，1： | 1 |
| 18 | Role of gamma-am inobutyric acid in the zona incerta in the control of luteinizing hormone release and ovulation 显示文摘 | Willson C A Jarnes M D Leigh A J | 1990 | Neuroendocrinology1990，52，： | 1 |
| 19 | Real-time monitoring of an industrial batch process显示文摘 | Jalel N A Leigh J I Fiacco M | 2006 | Computers & Chemical Engineering2006，30，10： | 1 |
| 20 | The role of hyaluronic acid in wound healing: assessment of clinical evidence 显示文摘 | Price R D Myers S Leigh M | 2005 | Am J Clin Dermatol2005，6，6： | 1 |
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