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| 1 | 用智能手机高血压指导或追踪应用程序进行家庭血压监测对未控制高血压患者的影响显示文摘移动应用程序(App)可能有助于改善高血压的自我管理。该文旨在探究促进家庭监测和高血压相关行为的人工智能手机指导App与血压追踪App对收缩压水平的影响。设计、设置和参与者:该研究为2组开放性随机临床试验。在2016-2017年招募高血压未控制的参与者,并随访6个月。在2019年4-12月进行数据分析。干预:干预组参与者接受智能手机指导App以促进家庭监测和高血压自我管理相关行为改变,并进行家庭血压监测。 | Persell SD Peprah YA Lipiszko D Lee JY Li JJ Ciolino JD Karmali KN Sato H 袁源(摘译) 练桂丽(审校) | 2020 | 中华高血压杂志2020，28，12： | 11 |
| 2 | Mechanosignaling activation of TGFβmaintains intervertebral disc homeostasis显示文摘Intervertebral disc(IVD) degeneration is the leading cause of disability with no disease-modifying treatment.IVD degeneration is associated with instable mechanical loading in the spine, but little is known about how mechanical stress regulates nucleus notochordal(NC) cells to maintain IVD homeostasis. Here we report that mechanical stress can result in excessive integrin α_vβ_6-mediated activation of transforming growth factor beta(TGFβ), decreased NC cell vacuoles, and increased matrix proteoglycan production, and results in degenerative disc disease(DDD). Knockout of TGFβ type II receptor(TβRII) or integrin α_v in the NC cells inhibited functional activity of postnatal NC cells and also resulted in DDD under mechanical loading.Administration of RGD peptide, TGFβ, and α_vβ_6-neutralizing antibodies attenuated IVD degeneration. Thus,integrin-mediated activation of TGFβ plays a critical role in mechanical signaling transduction to regulate IVD cell function and homeostasis. Manipulation of this signaling pathway may be a potential therapeutic target to modify DDD. | Qin Bian Lei Ma Amit Jain Janet L Crane Khaled Kebaish Mei Wan Zhengdong Zhang X Edward Guo Paul D Sponseller Cheryle A Seguin Lee H Riley Yongjun Wang Xu Cao | 2017 | Bone Research2017，5，1： | 9 |
| 3 | Fabrication of SAW Sensor for Detecting Chemical Agent显示文摘SAW sensors using five different types of polymer to detect of chemical agents(DMMP,CH_3CN,CH_2Cl_2,DCP) have been fabricated and its gas response characteristics were extensively investigated.The polymers used as the sensing material are polyisobutylene(PIB),polyepichlorohydrin(PECH),polydimethylsiloxane(PDMS),polyisoprene(PIP)and polybutadiene(PBD).Their thin films were coated on quartz substrate by spin coating technique.Three types of simulants gases,dimethylmethylphosphonate(DMMP),acetonitrile(CH_3CN)and dichloromethane(CH_2Cl_2),dichloropentane(DCP)were used as target gases,instead of the real nerve,blood,choking and vesicant agents.After spin coating of PIB and PECH,the substrates were heated to 65℃with N_2 flow for 1 h to remove the cyclohexane and ethylacetate which was used as solvent. PDMS was heated to 75℃with N_2 flow for 2 h to remove the ethylacetate which was used as solvent.PBD and PIP on the substrate were heated to 60℃with N_2 flow for 1 h to remove the benzen which was used as solvent.The sensing characteristics of the SAW sensors were measured by using E-5061A network analyzer. | J H Lee B S Joo J S Huh D D Lee | 2006 | 稀有金属材料与工程2006，35，A03： | 3 |
| 4 | Fault detection method with PCA and LDA and its application to induction motor显示文摘A feature extraction and fusion algorithm was constructed by combining principal component analysis(PCA) and linear discriminant analysis(LDA) to detect a fault state of the induction motor.After yielding a feature vector with PCA and LDA from current signal that was measured by an experiment,the reference data were used to produce matching values.In a diagnostic step,two matching values that were obtained by PCA and LDA,respectively,were combined by probability model,and a faulted signal was finally diagnosed.As the proposed diagnosis algorithm brings only merits of PCA and LDA into relief,it shows excellent performance under the noisy environment.The simulation was executed under various noisy conditions in order to demonstrate the suitability of the proposed algorithm and showed more excellent performance than the case just using conventional PCA or LDA. | JUNG D Y LEE S M 王洪梅 KIM J H LEE S H | 2010 | Journal of Central South University2010，17，6： | 3 |
| 5 | DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice显示文摘 | Meira Lisiane B Bugni James M Green Stephanie L Lee Chung-Wei Pang Bo Borenshtein Diana Rickman Barry H Rogers Arlin B Moroski-Erkul Catherine A McFaline Jose L Schauer David B Dedon Peter C Fox James G Samson Leona D | 2008 | Journal of Clinical Investigation2008，，7： | 2 |
| 6 | 韩国青春期女孩人乳头瘤病毒疫苗接种与严重不良事件的关联显示文摘人乳头瘤病毒(HPV)疫苗接种是预防宫颈癌最有效的措施之一,但公众对疫苗接种不良事件的担忧阻碍着HPV疫苗的推广应用。2016年6月,韩国将HPV疫苗纳入国家免疫规划,在12~13岁女孩中推行两剂次的二价或四价HPV疫苗接种。为增强公众对HPV疫苗的信心并补充韩国HPV疫苗的安全性数据,韩国成均馆大学利用免疫登记信息系统及国家卫生信息系统,开展了一项全国性队列研究以评估HPV疫苗接种与严重不良事件之间的关联性。 | Yoon D Lee JH Lee H 陈诗敏(编译) | 2021 | 中华医学杂志2021，101，24： | 2 |
| 7 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 8 | Detailed characterization of anodic bonding process between glass and thin-film coated silicon substrates 显示文摘 | Thomas M H Lee Lee D H Y | 2002 | Sensors and Actuators A2002，86，： | 2 |
| 9 | A study on a platinum-silicon carbide Schottky diodes as a hydrogen gas sensor 显示文摘 | Kim C K Lee J H Lee Y H Cho N I and Kim D J | 2000 | Sensors and Actuators B2000，66，： | 2 |
| 10 | A novel PWM scheme for a three-level voltage source inverter with GTO thyristors 显示文摘 | Lee Y H Suh B S Hyun D S | 1996 | IEEE Trans on Ind Appl1996，32，2： | 1 |
| 11 | Biotin synthase from Escherichia coli,an investigation of the low molecular weight and protein components required for activity in Vitro显示文摘 | Sanyal L Lee S L Flint D H | 1994 | J Am Chem Soc1994，116，： | 1 |
| 12 | Evaluation of seismic performance of multistory building structures based on the equivalent responses 显示文摘 | LEE D G CHOI W H CHEONG M C | 2006 | Engineering Structures2006，28，6： | 1 |
| 13 | Effects of thermal and chemical surface-flame interaction on flame quenching显示文摘 | KIM K T LEE D H KWON S | 2006 | Combust and Flame2006，146，： | 1 |
| 14 | Antiferroelectricity in multi- ferroic BiCrO3 epitaxial films 显示文摘 | Kim D H Lee H N Varela M | 2006 | Appl Phys Lett2006，89，16： | 1 |
| 15 | Hydrogen from natural gas:part I-autothermal reforming in an integrated fuel processor显示文摘 | LEE S H D APPLEGATE D V AHMED S | 2005 | Int J Hydrogen Energy2005，30，8： | 1 |
| 16 | Formation of ultrafine ferrite by strain- induced dynamic transformation in plain low carbon steel 显示文摘 | Choi J K Seo D H Lee J S | 2003 | ISIJ International2003，43，5： | 1 |
| 17 | Effect of dietary essential fatty acids on growth, body composition and blood chemistry of juvenile starry flounder Platichthys stellatus 显示文摘 | Lee S M Lee J H Kim K D | 2003 | Aquaculture2003，225，： | 1 |
| 18 | Chemical omposition of precipitation and wet deposition of major ions on Korea peninsula显示文摘 | Lee K B Hong H S Lee S D | 2000 | Atmospheric Environment2000，34，： | 1 |
| 19 | Composition and accumulation of secondary carotenoids in Chlorococcum sp显示文摘 | LEE Y K NG M L PHANG S M | 1997 | J Appl Phycol1997，9，： | 1 |
| 20 | Algorithms for non-negative matrix factorization 显示文摘 | Seung H S | 2001 | Advances in Neural Information Processing Systems2001，13，： | 1 |
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