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| 1 | Genome of Wild Mandarin and Domestication History of Mandarin显示文摘官员(柠檬 reticulata ) 是世界范围的最重要的柠檬庄稼之一。它的驯服被相信发生在华南,它是四几千年的官员耕作的中心之一。我们在 Nanling 区域附近收集了官员的自然野人口并且在附近栽培了 landraces。我们发现柠檬性的酸水平戏剧性地在栽培官员被减少。理解 ? 官员驯服的基因基础,我们 de novo 装配了野官员的一个草稿染色体并且分析了一套 104 个柠檬染色体。我们发现 Mangshan 官员是一种原始类型并且二个独立驯服事件发生了,分别地导致在北方和南方 Nanling 山的二组栽培官员(MD1 和 MD2 ) 。二个瓶颈和有效人口尺寸的二扩大为栽培官员的 MD1 组被识别。然而,在 MD2 组织 ? 在人口尺寸有长、连续的减少。MD1 和 MD2 官员从栽培 pummelo 种类显示出种间的基因渗入的不同模式。我们在官员的驯服期间在选择下面可能在基因在柠檬酸盐内容的规定包含了的 aconitate hydratase (ACO ) 识别了高分叉的一个区域,它是。这研究为现存野官员人口的地理起源提供具体基因证据并且使驯服和官员的进化历史清楚些。 | Lun Wang Fa He Yue Huang Jiaxian He Shuizhi Yang Jiwu Zeng Chongling Deng Xiaolin Jiang Yiwen Fang Shaohua Wen Rangwei Xu Huiwen Yu Xiaoming Yang Guangyan Zhong Chuanwu Chen Xiang Yan Changfu Zhou Hongyan Zhang Zongzhou Xie Robert M. Larkin Xiuxin Deng Qiang Xu | 2018 | Molecular Plant2018，11，8： | 14 |
| 2 | DEVELOPMENT OF COMMON WHEAT GERM-PLASM RESISTANT TO BARLEY YELLOW DWARF VIRUS BY BIOTECHNOLOGY显示文摘Barley yellow dwarf virus (BYDV) is one of the most serious wheat diseases in China. So far no resistance has been described in common wheat. A certain level of BYDV resistance was found in thirteen Triticeae species. Thinopyrum intermedium, two octoploids derived from TH. intermedium/wheat, Zhong 4 awnless and TAF46, and one disomic addition line, L1 derived from TAF46, showed good resistance to BYDV by enzyme linked immunosorbent assay (ELISA). Two wheat/TA. intermedium translocation lines, CPI 119880 and CPI 119899, showing good BYDV resistance were developed from L1 by using both CSph mutant and tissue culture. It is found that their BYDV resistance was controlled by a single dominant gene. Two cDNA probes pEleAcc3 and pPJN8 (E1-T1) were screened for detecting Th. intermedium DNA in wheat background. A specific band for the DNA of Th. intermedium and its derivatives was found in Southern hybridization. It is also possible to determine the size of the alien segment by comparing the relative density | 辛志勇 徐惠君 陈孝 林志珊 周广和 钱幼亭 成卓敏 P. J. LARKIN P. BANKS R. APPELS B. GLARKE AND R. I. S. BRETTELL | 1991 | Science China Chemistry1991，34，9： | 13 |
| 3 | Process parameter dependence of impurity-free interdiffusion in GaAs/AlxGa1-xAs and InyGa1-yAs/GaAs multipla quantum wells显示文摘 | B(u)rkner S Maler M Larkins E C | 1995 | J Electronic Materials1995，24，7： | 2 |
| 4 | Transcript accumulation and utilization of alternate and non-consensus splice sites in rice granule-bound starch synthase are temperature-sensitive and controlled by a single-nucleotide polymorphism显示文摘 | Larkin P D | | 0，，： | 2 |
| 5 | Road induced edge effects on a forest bird community in tropical Asia显示文摘Background: Edge effects cause changes in bird community richness, abundance, and/or distribution within a landscape, but the avian guilds most influenced can vary among regions. Although Southeast Asia has the highest rates of deforestation and projected species loss, and is currently undergoing an explosive growth in road infrastructure, there have been few studies of the effects of forest edges on avian communities in this region.Methods: We examined avian community structure in a dry evergreen forest in northeastern Thailand adjacent to a five-lane highway. We evaluated the richness and abundance of birds in 11 guilds at 24 survey points on three parallel transects perpendicular to the edge. At each point, 10-min surveys were conducted during February-August 2014 and March-August 2015. Vegetation measurements were conducted at 16 of the bird survey points and ambient noise was measured at all 24 survey points.Results: We found a strongly negative response to the forest edge for bark-gleaning, sallying, terrestrial, and understory insectivores and a weakly negative response for arboreal frugivore-insectivores, foliage gleaning insectivores, and raptors. Densities of trees and the percentage canopy cover were higher in the interior, and the ambient noise was lower. In contrast, arboreal nectarivore-insectivores responded positively to the forest edge, where there was a higher vegetation cover in the ground layer, a lower tree density, and a higher level of ambient noise.Conclusion: Planners should avoid road development in forests of high conservation value to reduce impacts on biodiversity. Where avoidance is impossible, a number of potential mitigation methods are available, but more detailed assessments of these are needed before they are applied in this region. | Daphawan Khamcha Richard T.Corlett Larkin A.Powell Tommaso Savini Antony J.Lynam George A.Gale | 2018 | Avian Research2018，9，2： | 2 |
| 6 | 儿童和成人住院期间心脏骤停时首次确诊的心脏节律与临床结局显示文摘Context: Cardiac arrests in adults are often due to ventricular fibrillation(VF) or pulseless ventricular tachycardia(VT), which are associated with better outcomes than asystole or pulseless electrical activity(PEA). Cardiac arrests in children are typically asystole or PEA. Objective: To test the hypothesis that children have relatively fewer in-hospital cardiac arrests associated with VF or pulseless VT compared with adults and, therefore, worse survival outcomes. Design, Setting, and Patients: A prospective observational study from a multicenter registry(National Registry of Cardiopulmonary Resuscitation) of cardiac arrests in 253 US and Canadian hospitals between January 1, 2000, and March 30, 2004. A total of 36 902 adults(≥ 18 years) and 880 children(<18 years) with pulseless cardiac arrests requiring chest compressions, defibrillation, or both were assessed. Cardiac arrests occurring in the delivery department, neonatal intensive care unit, and in the out-of-hospital setting were excluded. Main Outcome Measure: Survival to hospital discharge. Results: The rate of survival to hospital discharge following pulseless cardiac arrest was higher in children than adults(27% [236/880] vs 18% [6485/36 902]; adjusted odds ratio[OR], 2.29; 95% confidence interval[CI], 1.95- 2.68). Of these survivors, 65% (154/236) of children and 73% (4737/6485) of adults had good neurological outcome. The prevalence of VF or pulseless VT as the first documented pulseless rhythm was 14% (120/880) in children and 23% (8361/36 902) in adults(OR, 0.54; 95% CI, 0.44- 0.65; P<.001). The prevalence of asystole was 40% (350) in children and 35% (13 024) in adults(OR, 1.20; 95% CI, 1.10- 1.40; P=.006), whereas the prevalence of PEA was 24% (213) in children and 32% (11 963) in adults(OR, 0.67; 95% CI, 0.57- 0.78; P< .001). After adjustment for differences in preexisting conditions, interventions in place at time of arrest, witnessed and/or monitored status, time to defibrillation of VF or pulseless VT, intensive care unit location of arrest, and duration of cardiopulmonary resuscitation, only first documented pulseless arrest rhythm remained significantly associated with differential survival to discharge(24% [135/563] in children vs 11% [2719/24 987] in adults with asystole and PEA; adjusted OR, 2.73; 95% CI, 2.23- 3.32). Conclusions: In this multicenter registry of in-hospital cardiac arrest, the first documented pulseless arrest rhythm was typically asystole or PEA in both children and adults. Because of better survival after asystole and PEA, children had better outcomes than adults despite fewer cardiac arrests due to VF or pulseless VT. | Nadkarni V. M Larkin G. L Peberdy M. A 刘宇(译) 马超(校) | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，5： | 2 |
| 7 | In vitro corneal pathogenicity of Acanthamoeba显示文摘 | Larkin DF Berry M Easty DL | 1991 | Eye1991，5，5： | 1 |
| 8 | Epothilones in the treatment of cancer 显示文摘 | Larkin J M Kaye S B | 2006 | Expert Opin Investig Drugs2006，15，6： | 1 |
| 9 | Loop electrosurgical excision procedure of the cervix and time of delivery in subsequent pregnancy 显示文摘 | Sciscione A Larkin M OShea A | 2004 | Am J Obstet Gynecol2004，190，3： | 1 |
| 10 | Identification and characterization of cells infiltrating the graft and aqueous humour in rat corneal allograft rejection 显示文摘 | Larkin DFP Calder VL Lightman SL | 1997 | Clin Exp Immunol1997，107，： | 1 |
| 11 | Recognizing and treating syphilis in pregnancy 显示文摘 | Larkin JA Lit L Toney JA | 1998 | Medscape Womens Health1998，3，1： | 1 |
| 12 | Cytoktne and chemokine expression kinetics after corneal transplantation 显示文摘 | King WJ Comer RM Hudde T Larkin DF George AJ | 2000 | Transplantation2000，70，8： | 1 |
| 13 | First documented rhythm and clinical outcome from in-hospital cardiac arrest among children and adults 显示文摘 | Nadkarni VM Larkin GL Peberdy MA | 2006 | JAMA2006，295，1： | 1 |
| 14 | Effective tumor treatment using optimized ultrasound-mediated delivery of bleomycin 显示文摘 | Larkin J O Casey G D Tangney M et ol | 2008 | Ultrasound Med Biol2008，34，3： | 1 |
| 15 | Effect of successive watermelon plantings on Fusarium oxysporum and other microorganisms in soils suppressive and conducive to Fusarium wilt of watermelon 显示文摘 | Larkin R Hopkins D Martin F | 1993 | Phytopathology1993，83，10： | 1 |
| 16 | Positive and negative regulation of the IL-27 receptor during lymphoid cell activation 显示文摘 | VILLARINO A V LARKIN J 3RD SARIS C J | 2005 | J Inmmnol2005，174，12： | 1 |
| 17 | Membrane transport proteins in human melanoma: associations withturnout aggressiveness and metastasis显示文摘 | Walsh N Kennedy S Larkin AM | | Br J Cancer0，102，： | 1 |
| 18 | Partial characterization of the acidic and basic polypeptides of glycinin 显示文摘 | Moreira M A Hermodson M A Larkins B A | 1979 | Journal of Biological Chemistry1979，254，： | 1 |
| 19 | ClustalW2 and ClustalX version 2 显示文摘 | Larkin M A Blackshields G Brown N P | 2007 | Bioinformatics2007，23，： | 1 |
| 20 | Low-dose thalidomide seems to be effective in multiple myeloma显示文摘 | | 1999 | Lancet1999，354，9182： | 1 |
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