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| 1 | Inflammatory bowel disease: Moving toward a stem cell-based therapy显示文摘The incidence and prevalence of Crohn's disease (CD) and ulcerative colitis (UC), the two major forms of inflammatory bowel diseases (IBD), are rising in western countries. The modern hygienic lifestyle is probably at the root of a disease where, in genetically susceptible hosts, the intestinal commensal flora triggers dysregulated immune and inflammatory responses. Current therapies ranging from anti-inflammatory drugs to immunosuppressive regimens, remain inadequate. Advances in our understanding of the cell populations involved in the pathogenetic processes and recent findings on the regenerative, trophic and immunoregulatory potential of stem cells open new paths in IBD therapy. Hematopoietic and mesenchymal stem cells are catalyzing the attention of IBD investigators. This review highlights the pivotal fi ndings for stem cell-based approaches to IBD therapy and collects the encouraging results coming in from clinical trials. | Giacomo Lanzoni Giulia Roda Andrea Belluzzi Enrico Roda Gian Paolo Bagnara | 2008 | World Journal of Gastroenterology2008，14，29： | 9 |
| 2 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 3 | Infammatory bowel disease:moving toward a stem cell-based therapy显示文摘 | Lanzoni G Roda G Belluzzi A | 2008 | World J Gastroenterol2008，14，46： | 1 |
| 4 | Performance evaluation of a polypropylene-based draw-wired fibre for concrete structures 显示文摘 | Lanzoni L Nobili A Tarantino A | 2012 | Construction and Building Materials2012，28，4： | 1 |
| 5 | CHRONIC HEPATITIS C: HEPATIC IRON CONTENT DOES NOT CORRELATE WITH RESPONSE TO ANTIVIRAL THERAPY显示文摘 | Pereira Patricia da Silva Fucuta Silva Ivonete Sandra de Souza E Uehara Silvia Naomi de Oliveira Emori Christini Takemi Lanzoni Valéria Pereira Silva Antonio Eduardo Benedito Ferraz Maria Lucia Gomes | 2009 | Revista do Instituto de Medicina Tropical de S茫o Paulo2009，，6： | 1 |
| 6 | Serum humanepididymis protein 4 vs carbohydrate antigen 125 for ovariancancer diagnosis显示文摘 | Ferrar S Braga F Lanzoni M | 2013 | Clin Pathol2013，66，4： | 1 |
| 7 | An embedded portable biosensor system for bacterial concentration detection显示文摘 | GROSSI M LANZONI M POMPEI A | | 0，，03： | 1 |
| 8 | Anti-atherosclerotic activity of the calcium antagonist lacidipine in cholesterol fed hamsters显示文摘 | Cristofori P Lanzoni A Gavlraghi G | 2000 | J Biomed-Pharmacother2000，54，2： | 1 |
| 9 | C-erbB-2oncoproteinin gastric carcinoma:correlation with clinical stage and progno-sis显示文摘 | Oshima CT Lanzoni VP Iriya K | 2001 | Int J Biol Markers2001，16，4： | 1 |
| 10 | Prophylactic nasal continuous positive airways pressure in newborns of 28-31 weeks gestation:Multicentre randomised controlled clinical trial显示文摘 | Sandri F Ancora G Lanzoni A | 2004 | Arch Dis Child Fetal Neonatal Ed2004，89，5： | 1 |
| 11 | C-erbB-2 oncoprotein in gastric carcinoma: correlation with clinical stage and prognosis显示文摘 | Oshima CT Lanzoni VP Iriya K | 2001 | Int J Biol Markers2001，16，4： | 1 |
| 12 | A randomized double-blind study of the short-time treatment of obese patients with nonalcoholic fatty liver disease with ursodeoxycholic acid显示文摘 | SANTOS V N LANZONI V P SZEINFELS J | 2003 | Braz J Med Biol Res2003，36，6： | 1 |
| 13 | Prophylactic nasal continuous positive airways pressure in newborns of 28 -31 weeks gestation: multicentre randomize controlled clinical trial 显示文摘 | Sandri F Ancora G Lanzoni A | 2004 | Arch Dis Child Fetal Neonatal Ed2004，，5： | 1 |
| 14 | Prophylactic nasal Continuous positive airway pressure in newborns of 28-31 weeks gestation:Multicenter randomized controlled clinical trial显示文摘 | Sandri F Ancora G Lanzoni A | 2004 | Arch Dis Child Fetal Neonatal2004，89，： | 1 |
| 15 | Serum human epididymis protein 4 vs carbohydrate antigen125 for ovarian cancer diagnosis:a systematic review显示文摘 | Ferraro S Braga F Lanzoni M | 2013 | Clin Pathol2013，66，： | 1 |
| 16 | Histological evolution of hepatitis C virus infection after renal transplantation显示文摘 | Silvia Naomi Oliveira Uehara Christini Takemi Emori Patrícia da Silva Fucuta Pereira Renata M. Perez José Osmar Medina Pestana Valéria Pereira Lanzoni Ivonete Sandra Souza e Silva Antonio Eduardo Benedito Silva Maria Lucia Cardoso Gomes Ferraz | 2012 | Clin Transplant2012，，6： | 1 |
| 17 | Comparison of dry sliding friction and wear of Ti6Al4V alloy treated by plasma electrolytic oxidation and PVD coating显示文摘 | L. Ceschini E. Lanzoni C. Martini D. Prandstraller G. Sambogna | 2007 | Wear2007，，1： | 1 |
| 18 | Com- parison of dry sliding friction and wear of Ti6A14V alloy treated by plasma electrolytic oxidation and PVD coating 显示文摘 | CESEHINI L LANZONI E MARTINI C | 2008 | Wear2008，，264： | 1 |
| 19 | Real-time-dimensional echocardiography evaluation of congenital heart disease 显示文摘 | Balestrini L Fleishman C Lanzoni L | 2000 | J AmSoc Echocardiogr2000，13，3： | 1 |
| 20 | Increasing degrees of left ventricular filling impairment modulate left atrial function in humans显示文摘 | Prioli A Marino P Lanzoni L | 1998 | Am J Cardiol1998，82，： | 1 |
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